Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of LacR regulog to Streptococcus agalactiae 2603V/R

Reference regulog properties
Source regulog: LacR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: DeoR
Regulation mode: repressor
Biological process: Lactose utilization; Galactose utilization
Effector: D-galactose-6-phosphate
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus agalactiae 2603V/R
Orthologous TF(s) SAG1936
Regulated genes 4
Built upon 37 sites [see more]
Predicted regulatory interactions in Streptococcus agalactiae 2603V/R
Locus tag Position Score Sequence
Position: -69
Score: 9
Sequence: TACAAACAA-(1)-AACAAACAA
Locus tag: SAG1931
SAG1931 -69 9 TACAAACAA-(1)-AACAAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: lacA
Ortholog function: Galactose-6-phosphate isomerase, LacA subunit (EC 5.3.1.26)
Streptococcus agalactiae 2603V/R SAG1931 -69 9 TACAAACAA-(1)-AACAAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0453 -45 8.3 AACAAACAA-(1)-ATCGAACAA
Streptococcus gallolyticus UCN34 GALLO_0177 -136 8.2 AACATAAAA-(1)-AACAAACAA
-126 8.2 AACAAACAA-(1)-ATTAAAAAA
-116 7.5 ATTAAAAAA-(1)-ATTAAACAA
Streptococcus pyogenes M1 GAS SPy1708 -166 7.2 AACAAAATA-(1)-ACAAAACAA
-156 8.2 ACAAAACAA-(1)-AACAAACAT
Streptococcus uberis 0140J SUB1457 -53 8.3 ACCAAACAA-(1)-AACAAACAC
Position: -137
Score: 9.1
Sequence: AATAAACAA-(1)-AATAAACAA
Position: -127
Score: 7.9
Sequence: AATAAACAA-(1)-ATAAAATAA
Position: -123
Score: 7.1
Sequence: AACAAAATA-(1)-AATAAAAAA
Locus tag: SAG1935
SAG1935 -137 9.1 AATAAACAA-(1)-AATAAACAA
-127 7.9 AATAAACAA-(1)-ATAAAATAA
-123 7.1 AACAAAATA-(1)-AATAAAAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: gatA
Ortholog function: Galactose-specific PTS, EIIA component (EC 2.7.1.69)
Streptococcus agalactiae 2603V/R SAG1935 -137 9.1 AATAAACAA-(1)-AATAAACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1766 -155 8.6 ATAAAACAA-(1)-AATAAACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1522 -117 6.5 GAAAAAAAC-(1)-AACAAATAA
Streptococcus pyogenes M1 GAS SPy1711 -166 7.2 AACAAAATA-(1)-ACAAAACAA
-156 8.2 ACAAAACAA-(1)-AACAAACAT
Streptococcus uberis 0140J SUB1460 -155 8.8 AAATAACAA-(1)-AACAAACAA
-145 8.8 AACAAACAA-(1)-AAATAACAA
Position: -138
Score: 6.8
Sequence: ATTATACAA-(1)-ACAAAATAA
Position: -136
Score: 6
Sequence: TATACAAAA-(1)-AAAATAAAA
Position: -133
Score: 7.5
Sequence: ACAAAACAA-(1)-ATAAAACAT
Position: -128
Score: 6.2
Sequence: ACAAAATAA-(1)-ACATTACAA
Position: -123
Score: 6.1
Sequence: ATAAAACAT-(1)-ACAAGACAT
Position: 19
Score: 6.6
Sequence: TACAAAAAA-(1)-AATAGAAAA
Locus tag: SAG1936
SAG1936 -138 6.8 ATTATACAA-(1)-ACAAAATAA
-136 6 TATACAAAA-(1)-AAAATAAAA
-133 7.5 ACAAAACAA-(1)-ATAAAACAT
-128 6.2 ACAAAATAA-(1)-ACATTACAA
-123 6.1 ATAAAACAT-(1)-ACAAGACAT
19 6.6 TACAAAAAA-(1)-AATAGAAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: lacR
Ortholog function: Lactose utilization transcriptional regulator LacR, DeoR family
Lactococcus lactis subsp. cremoris SK11 LACR_D07 -105 -1.4 TTGTTTGAA-(1)-TTGTTTGTT
Streptococcus agalactiae 2603V/R SAG1936 -91 -2.3 TTGTTTATT-(1)-TTGTTTATT
Streptococcus gallolyticus UCN34 GALLO_0176 -201 -1.1 TTTTTTAAT-(1)-TTGTTTGTT
-191 -1.6 TTGTTTGTT-(1)-TTTTATGTT
Streptococcus mitis B6 smi_1041 -76 -2.3 TTGTTTTCT-(1)-TTGTTTTTT
Streptococcus pneumoniae TIGR4 SP_1182 -88 -0.6 ATTTTTGTT-(1)-TTGTTTTAT
-78 -1.4 TTGTTTTAT-(1)-TTGTTGTTT
Streptococcus pyogenes M1 GAS SPy1924 -113 -1.4 TTGTTAATT-(1)-TTGTTTTTT
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