Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of CmbR regulog to Streptococcus agalactiae 2603V/R

Reference regulog properties
Source regulog: CmbR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LysR
Regulation mode: repressor (activator)
Biological process: Cysteine metabolism
Effector: O-acetyl-L-serine
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus agalactiae 2603V/R
Orthologous TF(s) SAG1176, SAG1367
Regulated genes 6
Built upon 104 sites [see more]
Predicted regulatory interactions in Streptococcus agalactiae 2603V/R
Locus tag Position Score Sequence
Position: -96
Score: 5.5
Sequence: TTGATATAAAATCTTTATCAC
Position: -75
Score: 4.7
Sequence: CTGATAAGGAAATACTATTAT
Locus tag: SAG0290
SAG0290 -96 5.5 TTGATATAAAATCTTTATCAC
-75 4.7 CTGATAAGGAAATACTATTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyA
Ortholog function: Cystine ABC transporter, substrate-binding protein
Lactococcus lactis subsp. cremoris SK11 LACR_1009 -77 5.1 GCTATAAGTTTTTTTTATGGC
Lactococcus lactis subsp. lactis Il1403 L162009 -77 5.1 GCTATAAGTTTTTTTTATGGC
Streptococcus agalactiae 2603V/R SAG0290 -96 5.5 TTGATATAAAATCTTTATCAC
-75 4.7 CTGATAAGGAAATACTATTAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1582 -98 4.7 TTGATACTATTTTCTTATTGC
-76 4.2 TTGATAGAGAAATGATATTAT
Streptococcus gallolyticus UCN34 GALLO_0414 -100 5.2 CTGATAGTTTTTTCTTATCAA
Streptococcus mutans UA159 SMU.459 -102 5.8 GTGATAGAAAAATATTATCAC
-80 5 GTGATAGGAAAAAACTATTAT
Streptococcus uberis 0140J SUB1416 -98 4.5 GTCATATAAATAGCTAATTAC
-76 4.2 TTGATAGAAAAATGGTATTAT
Position: -97
Score: 4.9
Sequence: GTAATAGTTTTTCTTTATCAT
Locus tag: SAG1306
SAG1306 -97 4.9 GTAATAGTTTTTCTTTATCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: mmuP
Ortholog function: Predicted S-methylmethionine permease
Streptococcus agalactiae 2603V/R SAG1306 -97 4.9 GTAATAGTTTTTCTTTATCAT
Streptococcus thermophilus CNRZ1066 str0583 -22 4.8 GTGATAGTTTTTCTCTATCTC
Position: -109
Score: 4.1
Sequence: GCTAAAAATATAAAATATTAA
Locus tag: SAG2049
SAG2049 -109 4.1 GCTAAAAATATAAAATATTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Lactococcus lactis subsp. cremoris SK11 LACR_1368 -39 4.7 TTGATAAGATAGACCTATTAA
Lactococcus lactis subsp. lactis Il1403 L0100 -76 4.1 ATCATATTAAAAATGTATTAT
-39 4.7 TTGATAAGATAGACCTATTAA
Streptococcus agalactiae 2603V/R SAG2049 -109 4.1 GCTAAAAATATAAAATATTAA
Streptococcus gallolyticus UCN34 GALLO_1316 -221 4.2 ATAATAAATTTTATTAATCTA
-172 4.6 GTTATAGTTAAAAACTATAAT
Streptococcus gordonii str. Challis substr. CH1 SGO_0310 -182 4.2 GTTATAGTTTTTGATTATACC
Streptococcus mutans UA159 SMU.873 -188 4.6 GTTATAGATGAAAACTATAAC
Streptococcus pneumoniae TIGR4 SP_0585 -218 4.9 CTTATAAGAATTACTAATAAC
Streptococcus sanguinis SK36 SSA_0416 -182 4.3 GTCATAATTTCTACCTATAGC
Streptococcus suis 05ZYH33 SSU05_1774 -237 4.3 TTCATAGATAAAATCTATACC
Streptococcus thermophilus CNRZ1066 str0785 -119 4.2 GCTATACAAATATCTAATTAA
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