Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of MtaR regulog to Streptococcus pneumoniae R6

Reference regulog properties
Source regulog: MtaR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LysR
Regulation mode: repressor
Biological process: Methionine metabolism
Effector: Homocysteine
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pneumoniae R6
Orthologous TF(s) spr0593
Regulated genes 6
Built upon 72 sites [see more]
Predicted regulatory interactions in Streptococcus pneumoniae R6
Locus tag Position Score Sequence
Position: -99
Score: 6.5
Sequence: TATAGTTTTAAACTATA
Locus tag: spr0147
spr0147 -99 6.5 TATAGTTTTAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metQ
Ortholog function: Methionine ABC transporter, substrate-binding protein
Streptococcus mitis B6 smi_1944 -99 6.2 TATAGCTTTAAACTATA
Streptococcus pneumoniae TIGR4 SP_0149 -99 6.5 TATAGTTTTAAACTATA
Position: -64
Score: 4.6
Sequence: TATAAGGTAAAACTATA
Locus tag: spr0428
spr0428 -64 4.6 TATAAGGTAAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: COG1912
Ortholog function: Conserved hypothetical protein
Streptococcus gordonii str. Challis substr. CH1 SGO_0468 -30 4.5 TAAAGTTCAGGACTATA
Streptococcus mitis B6 smi_1812 -91 4.6 TATAAGGTAAAACTATA
Streptococcus mutans UA159 SMU.1936c -110 5.4 TATAGGTAATAACTATA
Streptococcus pneumoniae TIGR4 SP_0481 -64 4.6 TATAAGGTAAAACTATA
Streptococcus thermophilus CNRZ1066 str0304 -100 4.5 CATAGCCAAAGGCTATA
Streptococcus uberis 0140J SUB0314 -106 6.3 TATAGTTTTAGACTATA
Position: -35
Score: 6.2
Sequence: TATAGTTTGAAACTATA
Locus tag: spr0729
spr0729 -35 6.2 TATAGTTTGAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: folD
Ortholog function: Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
Streptococcus mitis B6 smi_0869 -35 6.2 TATAGTTTGAAACTATA
Streptococcus mutans UA159 SMU.572 -93 4.6 TATAATATTTAAATATA
Streptococcus pneumoniae TIGR4 SP_0825 -98 6.3 TATAGTTTAAAGCTATA
Position: -156
Score: 6.4
Sequence: TATAGTTTCAAACTATA
Locus tag: spr1109
spr1109 -156 6.4 TATAGTTTCAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: fhs
Ortholog function: Formate--tetrahydrofolate ligase (EC 6.3.4.3)
Streptococcus gordonii str. Challis substr. CH1 SGO_1210 -42 4.8 TTTTGTTATAATCTATA
Streptococcus mitis B6 smi_1192 -157 6.4 TATAGTTTCAAACTATA
Streptococcus pneumoniae TIGR4 SP_1229 -156 6.4 TATAGTTTCAAACTATA
Streptococcus uberis 0140J SUB0942 -129 4.6 TAAAGATATACACTATA
Position: -93
Score: 6.2
Sequence: TATAGTTTGAAACTATA
Locus tag: spr1377
spr1377 -93 6.2 TATAGTTTGAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metB
Ortholog function: Cystathionine gamma-synthase (EC 2.5.1.48)
Streptococcus gallolyticus UCN34 GALLO_1768 -140 5.2 TATAGTTTTTACTTATA
Streptococcus gordonii str. Challis substr. CH1 SGO_1636 -101 6.1 TATAGTTTCAGACTATA
Streptococcus mitis B6 smi_1508 -93 6.2 TATAGTTTGAAACTATA
Streptococcus pneumoniae TIGR4 SP_1525 -93 6.2 TATAGTTTGAAACTATA
Streptococcus sanguinis SK36 SSA_1737 -44 6.4 TATAGTTTCAAACTATA
Streptococcus thermophilus CNRZ1066 str0352 -130 5.9 TATAGTAATAAACTATA
Position: -109
Score: 5.4
Sequence: TATAATTGAAAACTATA
Locus tag: spr1434
spr1434 -109 5.4 TATAATTGAAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metA
Ortholog function: Homoserine O-succinyltransferase (EC 2.3.1.46)
Streptococcus gallolyticus UCN34 GALLO_0824 -105 5.9 TATAGCTAAAAACTATA
-71 5.4 TATAATTGAAAACTATA
Streptococcus gordonii str. Challis substr. CH1 SGO_1002 -97 5.6 CATAGTTTCAGGCTATA
-63 5.4 TATAATTGAAAACTATA
Streptococcus mutans UA159 SMU.1466 -102 5.3 TATAGTTGGAACCTATA
-68 5.2 TATATTTGATAACTATA
Streptococcus pneumoniae TIGR4 SP_1576 -109 5.4 TATAATTGAAAACTATA
Streptococcus sanguinis SK36 SSA_1420 -145 5.8 CATAGTTTCTAACTATA
-111 5.4 TATAATTGAAAACTATA
Streptococcus thermophilus CNRZ1066 str1222 -103 5.6 TATAGTTTAAAGTTATA