Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of LacR regulog to Streptococcus pneumoniae SP6-BS73

Reference regulog properties
Source regulog: LacR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: DeoR
Regulation mode: repressor
Biological process: Lactose utilization; Galactose utilization
Effector: D-galactose-6-phosphate
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pneumoniae SP6-BS73
Orthologous TF(s) CGSSp6BS73_03556
Regulated genes 5
Built upon 37 sites [see more]
Predicted regulatory interactions in Streptococcus pneumoniae SP6-BS73
Locus tag Position Score Sequence
Position: -199
Score: 6.4
Sequence: ACACAACAA-(1)-AATATAAAA
Position: -189
Score: 6.4
Sequence: AATATAAAA-(1)-AAGAGACAA
Position: -164
Score: 6.4
Sequence: AACAGAAAG-(1)-AATTAACAA
Locus tag: CGSSp6BS73_02862
CGSSp6BS73_02862 -199 6.4 ACACAACAA-(1)-AATATAAAA
-189 6.4 AATATAAAA-(1)-AAGAGACAA
-164 6.4 AACAGAAAG-(1)-AATTAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: gatA
Ortholog function: Galactose-specific PTS, EIIA component (EC 2.7.1.69)
Streptococcus agalactiae 2603V/R SAG1935 -137 9.1 AATAAACAA-(1)-AATAAACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1766 -155 8.6 ATAAAACAA-(1)-AATAAACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1522 -117 6.5 GAAAAAAAC-(1)-AACAAATAA
Streptococcus pyogenes M1 GAS SPy1711 -166 7.2 AACAAAATA-(1)-ACAAAACAA
-156 8.2 ACAAAACAA-(1)-AACAAACAT
Streptococcus uberis 0140J SUB1460 -155 8.8 AAATAACAA-(1)-AACAAACAA
-145 8.8 AACAAACAA-(1)-AAATAACAA
Position: -155
Score: 6.5
Sequence: AGTAAACTA-(1)-AAACAACAA
Locus tag: CGSSp6BS73_03556
CGSSp6BS73_03556 -155 6.5 AGTAAACTA-(1)-AAACAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: lacR
Ortholog function: Lactose utilization transcriptional regulator LacR, DeoR family
Lactococcus lactis subsp. cremoris SK11 LACR_D07 -105 -1.4 TTGTTTGAA-(1)-TTGTTTGTT
Streptococcus agalactiae 2603V/R SAG1936 -91 -2.3 TTGTTTATT-(1)-TTGTTTATT
Streptococcus gallolyticus UCN34 GALLO_0176 -201 -1.1 TTTTTTAAT-(1)-TTGTTTGTT
-191 -1.6 TTGTTTGTT-(1)-TTTTATGTT
Streptococcus mitis B6 smi_1041 -76 -2.3 TTGTTTTCT-(1)-TTGTTTTTT
Streptococcus pneumoniae TIGR4 SP_1182 -88 -0.6 ATTTTTGTT-(1)-TTGTTTTAT
-78 -1.4 TTGTTTTAT-(1)-TTGTTGTTT
Streptococcus pyogenes M1 GAS SPy1924 -113 -1.4 TTGTTAATT-(1)-TTGTTTTTT
Position: -205
Score: 6.3
Sequence: ACTAAAAAA-(1)-TTTAAAAAA
Locus tag: CGSSp6BS73_03581
CGSSp6BS73_03581 -205 6.3 ACTAAAAAA-(1)-TTTAAAAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: lacT
Ortholog function: Lactose utilization transcriptional antiterminator LacT, BglG family
Streptococcus gallolyticus UCN34 GALLO_1046 -197 7.8 AAAACAAAA-(1)-AATAAACAA
Streptococcus sanguinis SK36 SSA_1695 -79 6.3 TTAAAACAA-(2)-AAATAATAT
Streptococcus suis 05ZYH33 SSU05_1039 -7 7.2 ATTAAACAT-(1)-AATAAACGA
Position: -153
Score: 7.1
Sequence: AGTAAAAAA-(1)-AAATAACAA
Position: -149
Score: 6.4
Sequence: AAAAATAAA-(1)-AACAAAAAC
Position: -146
Score: 6.9
Sequence: AATAAATAA-(1)-AAAAACAAA
Position: -143
Score: 8.1
Sequence: AAATAACAA-(1)-AACAAACAC
Locus tag: CGSSp6BS73_03606
CGSSp6BS73_03606 -153 7.1 AGTAAAAAA-(1)-AAATAACAA
-149 6.4 AAAAATAAA-(1)-AACAAAAAC
-146 6.9 AATAAATAA-(1)-AAAAACAAA
-143 8.1 AAATAACAA-(1)-AACAAACAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: lacA
Ortholog function: Galactose-6-phosphate isomerase, LacA subunit (EC 5.3.1.26)
Lactococcus lactis subsp. cremoris SK11 LACR_D06 -214 8.6 AACAAATAA-(1)-AAAAAACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1526 -117 6.5 GAAAAAAAC-(1)-AACAAATAA
Streptococcus mitis B6 smi_1026 -281 8.1 AAAACACAA-(1)-AACAAACAT
Streptococcus pneumoniae TIGR4 SP_1193 -143 8.8 AAATAACAA-(1)-AACAAACAA
Streptococcus suis 05ZYH33 SSU05_1043 -7 7.2 ATTAAACAT-(1)-AATAAACGA
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