Propagation of CmbR regulog to Streptococcus thermophilus LMG 18311

Reference regulog properties
Source regulog:	CmbR - Streptococcaceae
Regulator type:	Transcription factor
Regulator family:	LysR
Regulation mode:	repressor (activator)
Biological process:	Cysteine metabolism
Effector:	O-acetyl-L-serine
Phylum:	Firmicutes
Propagated regulon:
Target genome	Streptococcus thermophilus LMG 18311
Orthologous TF(s)	stu0520, stu0872
Regulated genes	12

Built upon 104 sites [see more]

Predicted regulatory interactions in *Streptococcus thermophilus LMG 18311*
	Locus tag	Position	Score	Sequence
Position: -97 Score: 5.7 Sequence: GTGATAGTATTTTCTTATCAC Locus tag: stu0291
	stu0291	-97	5.7	GTGATAGTATTTTCTTATCAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: gshT
Ortholog function: Predicted glutathione ABC transporter, substrate-binding protein
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0381	-75	5	TTGATAGGAATTAATTATTAG
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1680	-41	5	ATGATAAACTAATCTTATGAA
Streptococcus gallolyticus UCN34	GALLO_1845	-122	6	GTGATAAGTTTTATTTATCAC
Streptococcus mitis B6	smi_1945	-99	5.1	GCCATAAAGAAAACCTATCAC
Streptococcus mutans UA159	SMU.1942c	-98	6	GTGATAGAATTTTCTTATCAC
		-76	4.6	GTGATAGAAATTATATAATAG
Streptococcus pyogenes M1 GAS	SPy0317	-75	4.5	TTGATAGGAATCAATTATTAG
Streptococcus thermophilus CNRZ1066	str0296	-98	5.7	GTGATAGTATTTTCTTATCAC
Streptococcus uberis 0140J	SUB0365	-93	4.9	GTGATAGAGAACTATTATCAT
		-71	4.2	GCGATAGTGAATCACTATTAG

Position: -98 Score: 5.7 Sequence: GTGATAGTATTTTCTTATCAC Locus tag: stu0296
	stu0296	-98	5.7	GTGATAGTATTTTCTTATCAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: gshT
Ortholog function: Predicted glutathione ABC transporter, substrate-binding protein
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0381	-75	5	TTGATAGGAATTAATTATTAG
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1680	-41	5	ATGATAAACTAATCTTATGAA
Streptococcus gallolyticus UCN34	GALLO_1845	-122	6	GTGATAAGTTTTATTTATCAC
Streptococcus mitis B6	smi_1945	-99	5.1	GCCATAAAGAAAACCTATCAC
Streptococcus mutans UA159	SMU.1942c	-98	6	GTGATAGAATTTTCTTATCAC
		-76	4.6	GTGATAGAAATTATATAATAG
Streptococcus pyogenes M1 GAS	SPy0317	-75	4.5	TTGATAGGAATCAATTATTAG
Streptococcus thermophilus CNRZ1066	str0296	-98	5.7	GTGATAGTATTTTCTTATCAC
Streptococcus uberis 0140J	SUB0365	-93	4.9	GTGATAGAGAACTATTATCAT
		-71	4.2	GCGATAGTGAATCACTATTAG

Position: -132 Score: 4.5 Sequence: GTTATAGTAATAAACTATATC Locus tag: stu0352
	stu0352	-132	4.5	GTTATAGTAATAAACTATATC
Supported by regulated orthologs from reference regulons
Ortholog gene name: metB1
Ortholog function: Cystathionine gamma-synthase (EC 2.5.1.48)
Lactococcus lactis subsp. lactis Il1403	L0102	-132	4.3	GCCATAGGCAAGTTTTATTAT
Streptococcus gallolyticus UCN34	GALLO_1768	-142	5	GTTATAGTTTTTACTTATAGC
Streptococcus mutans UA159	SMU.1675	-110	4.3	CTTATAGTTTCTTTTTATAGC
Streptococcus suis 05ZYH33	SSU05_1562	-120	5.1	GTTATAAAGAAAAACTATAAC
Streptococcus thermophilus CNRZ1066	str0352	-132	4.5	GTTATAGTAATAAACTATATC

Position: -16 Score: 5.2 Sequence: ATGATAAAATTTTTTTATGGA Locus tag: stu0367
	stu0367	-16	5.2	ATGATAAAATTTTTTTATGGA
Supported by regulated orthologs from reference regulons
Ortholog gene name: COG1739
Ortholog function: Conserved hypothetical protein
Streptococcus thermophilus CNRZ1066	str0367	-16	5.2	ATGATAAAATTTTTTTATGGA

Position: -108 Score: 5.3 Sequence: TTTATAAAAATTTCATATCAG Locus tag: stu0452
	stu0452	-108	5.3	TTTATAAAAATTTCATATCAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: homR
Ortholog function: Homocysteine biosynthesis transcriptional regulato HomR, LysR family
Streptococcus gallolyticus UCN34	GALLO_1277	-175	4.4	ATAATCTAAATTTTTTATTAT
		-113	5.9	GTTATAAAAAAATCTTATCAC
Streptococcus mutans UA159	SMU.930c	-175	5.3	GCTATAAATTTTATTTATGAC
		-110	5	GCCATAAGAAAAAGTTATCAC
Streptococcus thermophilus CNRZ1066	str0452	-108	5.3	TTTATAAAAATTTCATATCAG

Position: -22 Score: 4.8 Sequence: GTGATAGTTTTTCTCTATCTC Locus tag: stu0583
	stu0583	-22	4.8	GTGATAGTTTTTCTCTATCTC
Supported by regulated orthologs from reference regulons
Ortholog gene name: mmuP
Ortholog function: Predicted S-methylmethionine permease
Streptococcus agalactiae 2603V/R	SAG1306	-97	4.9	GTAATAGTTTTTCTTTATCAT
Streptococcus thermophilus CNRZ1066	str0583	-22	4.8	GTGATAGTTTTTCTCTATCTC

Position: -119 Score: 4.2 Sequence: GCTATACAAATATCTAATTAA Locus tag: stu0785
	stu0785	-119	4.2	GCTATACAAATATCTAATTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Lactococcus lactis subsp. cremoris SK11	LACR_1368	-39	4.7	TTGATAAGATAGACCTATTAA
Lactococcus lactis subsp. lactis Il1403	L0100	-76	4.1	ATCATATTAAAAATGTATTAT
		-39	4.7	TTGATAAGATAGACCTATTAA
Streptococcus agalactiae 2603V/R	SAG2049	-109	4.1	GCTAAAAATATAAAATATTAA
Streptococcus gallolyticus UCN34	GALLO_1316	-221	4.2	ATAATAAATTTTATTAATCTA
		-172	4.6	GTTATAGTTAAAAACTATAAT
Streptococcus gordonii str. Challis substr. CH1	SGO_0310	-182	4.2	GTTATAGTTTTTGATTATACC
Streptococcus mutans UA159	SMU.873	-188	4.6	GTTATAGATGAAAACTATAAC
Streptococcus pneumoniae TIGR4	SP_0585	-218	4.9	CTTATAAGAATTACTAATAAC
Streptococcus sanguinis SK36	SSA_0416	-182	4.3	GTCATAATTTCTACCTATAGC
Streptococcus suis 05ZYH33	SSU05_1774	-237	4.3	TTCATAGATAAAATCTATACC
Streptococcus thermophilus CNRZ1066	str0785	-119	4.2	GCTATACAAATATCTAATTAA

Position: -83 Score: 4.6 Sequence: GTTATAACTTTATTTTATAGG Locus tag: stu0790
	stu0790	-83	4.6	GTTATAACTTTATTTTATAGG
Supported by regulated orthologs from reference regulons
Ortholog gene name: dfpB
Ortholog function: Phosphopantothenoylcysteine synthetase (EC 6.3.2.5)
Lactococcus lactis subsp. lactis Il1403	L167675	-59	4.8	TTGAAAAAATATTTTTATTAG
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0944	-177	4.7	TTGATAGTATCATTATATCAC
		-10	4.3	CTGATAAAATATGGCTATGAA
Streptococcus thermophilus CNRZ1066	str0790	-83	4.3	GTTATAACTTTATTTTATATG

Position: -237 Score: 4.8 Sequence: GTTATATCTTTTCTTTATCAC Position: -215 Score: 5.2 Sequence: TTGATAAAAAATACATATTAT Locus tag: stu1582
	stu1582	-237	4.8	GTTATATCTTTTCTTTATCAC
		-215	5.2	TTGATAAAAAATACATATTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: str1582
Ortholog function: Predicted polar amino acid ABC transporter, permease protein 1
Streptococcus gallolyticus UCN34	GALLO_1237	-96	5.3	GCTATAAAAATTATTTATGGC
Streptococcus gordonii str. Challis substr. CH1	SGO_0985	-139	5.2	CTTATAAATTTTTTCTATCAG
		-117	4.9	CCGATAAAATATACATATTAT
Streptococcus mitis B6	smi_1436	-102	5.5	ATGATAAAAAATCCTTATAAC
		-80	4.4	GCAATAAAAAATAGATATTAT
Streptococcus pneumoniae TIGR4	SP_0711	-140	4.4	GCAATAAAAAATAGATATTAT
Streptococcus thermophilus CNRZ1066	str1582	-237	4.8	GTTATATCTTTTCTTTATCAC
		-215	5.2	TTGATAAAAAATACATATTAT

Position: -100 Score: 5.6 Sequence: GTGATATGATTTCCTTATCAC Locus tag: stu1653
	stu1653	-100	5.6	GTGATATGATTTCCTTATCAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyB
Ortholog function: Cystine ABC transporter, permease protein
Lactococcus lactis subsp. cremoris SK11	LACR_1010	-77	5.1	GCTATAAGTTTTTTTTATGGC
Lactococcus lactis subsp. lactis Il1403	L163056	-77	5.1	GCTATAAGTTTTTTTTATGGC
Streptococcus agalactiae 2603V/R	SAG0291	-96	5.5	TTGATATAAAATCTTTATCAC
		-75	4.7	CTGATAAGGAAATACTATTAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1719	-99	5.3	GTGATAAGTTTTGCTTATTGC
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1580	-106	5	GCGATAGGCTTTTCTTATCGT
Streptococcus gallolyticus UCN34	GALLO_0415	-100	5.2	CTGATAGTTTTTTCTTATCAA
Streptococcus gordonii str. Challis substr. CH1	SGO_0578	-170	4.7	GTCATAAAATTTGCTTATACC
		-148	4.3	TTGATAAATAATTTATACTGT
Streptococcus mitis B6	smi_1382	-164	4.7	GAGATAGTTTTTACTTATCTC
		-142	5	TTGATAGATAAAATATATAGC
Streptococcus mutans UA159	SMU.460	-102	5.8	GTGATAGAAAAATATTATCAC
		-80	5	GTGATAGGAAAAAACTATTAT
Streptococcus pneumoniae TIGR4	SP_1461	-164	4.3	GAAATAGTTTTTATCTATCTC
		-142	5.2	TTGATAGATAAAATATATAAC
Streptococcus sanguinis SK36	SSA_1868	-250	5.4	GTGATATACTTTTCTTATCGC
		-228	5.3	GTGATAAGAAAAATATATTAG
Streptococcus thermophilus CNRZ1066	str1653	-217	5.8	GTGATATGATTTACTTATCAC
Streptococcus uberis 0140J	SUB1415	-80	4.8	GTGATAGGCTTTAACTATTGC

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of CmbR regulog to Streptococcus thermophilus LMG 18311

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --