Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of CmbR regulog to Streptococcus uberis 0140J

Reference regulog properties
Source regulog: CmbR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LysR
Regulation mode: repressor (activator)
Biological process: Cysteine metabolism
Effector: O-acetyl-L-serine
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus uberis 0140J
Orthologous TF(s) SUB0728, SUB1044
Regulated genes 5
Built upon 104 sites [see more]
Predicted regulatory interactions in Streptococcus uberis 0140J
Locus tag Position Score Sequence
Position: -93
Score: 4.9
Sequence: GTGATAGAGAACTATTATCAT
Locus tag: SUB0365
SUB0365 -93 4.9 GTGATAGAGAACTATTATCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: gshT
Ortholog function: Predicted glutathione ABC transporter, substrate-binding protein
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0381 -75 5 TTGATAGGAATTAATTATTAG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1680 -41 5 ATGATAAACTAATCTTATGAA
Streptococcus gallolyticus UCN34 GALLO_1845 -122 6 GTGATAAGTTTTATTTATCAC
Streptococcus mitis B6 smi_1945 -99 5.1 GCCATAAAGAAAACCTATCAC
Streptococcus mutans UA159 SMU.1942c -98 6 GTGATAGAATTTTCTTATCAC
-76 4.6 GTGATAGAAATTATATAATAG
Streptococcus pyogenes M1 GAS SPy0317 -75 4.5 TTGATAGGAATCAATTATTAG
Streptococcus thermophilus CNRZ1066 str0296 -98 5.7 GTGATAGTATTTTCTTATCAC
Streptococcus uberis 0140J SUB0365 -93 4.9 GTGATAGAGAACTATTATCAT
-71 4.2 GCGATAGTGAATCACTATTAG
Position: 0
Score: 4.3
Sequence: ATGATAGAATATGATTTTAAA
Locus tag: SUB0427
SUB0427 0 4.3 ATGATAGAATATGATTTTAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metC
Ortholog function: L-cysteine desulfhydrase
Streptococcus agalactiae 2603V/R SAG1587 -152 4.5 ATGATAAATTAAAATAATAAA
Streptococcus gallolyticus UCN34 GALLO_1767 -142 5 GTTATAGTTTTTACTTATAGC
Streptococcus mutans UA159 SMU.1674 -110 4.3 CTTATAGTTTCTTTTTATAGC
Streptococcus suis 05ZYH33 SSU05_1561 -120 5.1 GTTATAAAGAAAAACTATAAC
Streptococcus thermophilus CNRZ1066 str0353 -132 4.5 GTTATAGTAATAAACTATATC
Position: -104
Score: 5.1
Sequence: ATGATAAGCCTTTCCTATCAC
Locus tag: SUB1379
SUB1379 -104 5.1 ATGATAAGCCTTTCCTATCAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysK
Ortholog function: Cysteine synthase (EC 2.5.1.47)
Lactococcus lactis subsp. lactis Il1403 L0089 -79 5.3 GCTATAAAAAAATCTTATAGC
Lactococcus lactis subsp. lactis Il1403 L0088 -87 4.5 ATCATAAATTTTTTTTAGAGC
Streptococcus mitis B6 smi_2060 -98 5.3 GATATAAAAAAATCCTATCAC
Streptococcus thermophilus CNRZ1066 str0366 -16 5.2 ATGATAAAATTTTTTTATGGA
Streptococcus uberis 0140J SUB1379 -104 5.1 ATGATAAGCCTTTCCTATCAC
Position: -80
Score: 4.8
Sequence: GTGATAGGCTTTAACTATTGC
Locus tag: SUB1415
SUB1415 -80 4.8 GTGATAGGCTTTAACTATTGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyB
Ortholog function: Cystine ABC transporter, permease protein
Lactococcus lactis subsp. cremoris SK11 LACR_1010 -77 5.1 GCTATAAGTTTTTTTTATGGC
Lactococcus lactis subsp. lactis Il1403 L163056 -77 5.1 GCTATAAGTTTTTTTTATGGC
Streptococcus agalactiae 2603V/R SAG0291 -96 5.5 TTGATATAAAATCTTTATCAC
-75 4.7 CTGATAAGGAAATACTATTAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1719 -99 5.3 GTGATAAGTTTTGCTTATTGC
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1580 -106 5 GCGATAGGCTTTTCTTATCGT
Streptococcus gallolyticus UCN34 GALLO_0415 -100 5.2 CTGATAGTTTTTTCTTATCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0578 -170 4.7 GTCATAAAATTTGCTTATACC
-148 4.3 TTGATAAATAATTTATACTGT
Streptococcus mitis B6 smi_1382 -164 4.7 GAGATAGTTTTTACTTATCTC
-142 5 TTGATAGATAAAATATATAGC
Streptococcus mutans UA159 SMU.460 -102 5.8 GTGATAGAAAAATATTATCAC
-80 5 GTGATAGGAAAAAACTATTAT
Streptococcus pneumoniae TIGR4 SP_1461 -164 4.3 GAAATAGTTTTTATCTATCTC
-142 5.2 TTGATAGATAAAATATATAAC
Streptococcus sanguinis SK36 SSA_1868 -250 5.4 GTGATATACTTTTCTTATCGC
-228 5.3 GTGATAAGAAAAATATATTAG
Streptococcus thermophilus CNRZ1066 str1653 -217 5.8 GTGATATGATTTACTTATCAC
Streptococcus uberis 0140J SUB1415 -80 4.8 GTGATAGGCTTTAACTATTGC
Position: -98
Score: 4.5
Sequence: GTCATATAAATAGCTAATTAC
Locus tag: SUB1416
SUB1416 -98 4.5 GTCATATAAATAGCTAATTAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyA
Ortholog function: Cystine ABC transporter, substrate-binding protein
Lactococcus lactis subsp. cremoris SK11 LACR_1009 -77 5.1 GCTATAAGTTTTTTTTATGGC
Lactococcus lactis subsp. lactis Il1403 L162009 -77 5.1 GCTATAAGTTTTTTTTATGGC
Streptococcus agalactiae 2603V/R SAG0290 -96 5.5 TTGATATAAAATCTTTATCAC
-75 4.7 CTGATAAGGAAATACTATTAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1582 -98 4.7 TTGATACTATTTTCTTATTGC
-76 4.2 TTGATAGAGAAATGATATTAT
Streptococcus gallolyticus UCN34 GALLO_0414 -100 5.2 CTGATAGTTTTTTCTTATCAA
Streptococcus mutans UA159 SMU.459 -102 5.8 GTGATAGAAAAATATTATCAC
-80 5 GTGATAGGAAAAAACTATTAT
Streptococcus uberis 0140J SUB1416 -98 4.5 GTCATATAAATAGCTAATTAC
-76 4.2 TTGATAGAAAAATGGTATTAT
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