Propagation of Rex regulog to Streptococcus pneumoniae CDC1873-00
| Source regulog: | Rex - Streptococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | Rex |
| Regulation mode: | repressor |
| Biological process: | Energy metabolism |
| Effector: | NADH |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Streptococcus pneumoniae CDC1873-00 |
| Orthologous TF(s) | SpneCDC1_010100003085 |
| Regulated genes | 12 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -307
Score: 4.3 Sequence: TTGTTGAAATTGGAACAA
Locus tag: SpneCDC1_010100000820
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| SpneCDC1_010100000820 | -307 | 4.3 | TTGTTGAAATTGGAACAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: pgk | ||||
| Ortholog function: Phosphoglycerate kinase (EC 2.7.2.3) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_0248 | -91 | 4.5 | TTGTGATATAATTAACCT |
| Lactococcus lactis subsp. lactis Il1403 | L0010 | -91 | 4.5 | TTGTGATATAATTAACCT |
| Streptococcus agalactiae 2603V/R | SAG1766 | -84 | 4.7 | TTGTGAAAAAGTAATCAA |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0272 | -96 | 4.3 | TTGTGAAATAGTTAATTT |
| Streptococcus gallolyticus UCN34 | GALLO_1995 | -137 | 4.4 | TTGTAAAATGATACAGAA |
| -47 | 4.5 | TTGTGATATAATTAGCAT | ||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0209 | -46 | 4.7 | TTGTGATATAATTATCAT |
| Streptococcus mutans UA159 | SMU.361 | -47 | 4.7 | TTGTGATATAATTATCAT |
| Streptococcus sanguinis SK36 | SSA_0302 | -87 | 4.5 | TTGTGAAAATTTTCTTTA |
| Streptococcus suis 05ZYH33 | SSU05_0157 | -87 | 4.4 | TTGTGAAAAAAATATCTT |
| Streptococcus uberis 0140J | SUB1629 | -96 | 4.5 | TTGTGAAAAAAATAATTT |
|
Position: -62
Score: 4.5 Sequence: AAGTGATAAAATGAACAA
Locus tag: SpneCDC1_010100001315
|
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| SpneCDC1_010100001315 | -62 | 4.5 | AAGTGATAAAATGAACAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: fba | ||||
| Ortholog function: Fructose-bisphosphate aldolase class II (EC 4.1.2.13) | ||||
| Streptococcus gallolyticus UCN34 | GALLO_0255 | -60 | 4.2 | TTGTGATAAAATGTACGT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1745 | -61 | 4.6 | AAGTGATAAAATAAACAA |
| Streptococcus mutans UA159 | SMU.99 | -61 | 4.6 | AAGTGATAAAATAAACAA |
| Streptococcus pneumoniae TIGR4 | SP_0605 | -62 | 4.5 | AAGTGATAAAATGAACAA |
| Streptococcus sanguinis SK36 | SSA_1992 | -62 | 4.6 | AAGTGATAAAATAAACAA |
|
Position: -28
Score: 5.1 Sequence: TTGATAAAAACATCACAA
Locus tag: SpneCDC1_010100002610
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| SpneCDC1_010100002610 | -28 | 5.1 | TTGATAAAAACATCACAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: hemH | ||||
| Ortholog function: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1) | ||||
| Streptococcus mitis B6 | smi_1138 | -28 | 5.1 | TTGATAAAAACATCACAA |
| Streptococcus pneumoniae TIGR4 | SP_1009 | -28 | 5.1 | TTGATAAAAACATCACAA |
|
Position: -57
Score: 5 Sequence: TTGTTGATTTTTTCACAA
Locus tag: SpneCDC1_010100003085
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| SpneCDC1_010100003085 | -57 | 5 | TTGTTGATTTTTTCACAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: rex | ||||
| Ortholog function: Redox-sensitive transcriptional regulator Rex, Rex family | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1156 | -74 | 5.3 | TTGATAAAATTATCACAA |
| Lactococcus lactis subsp. lactis Il1403 | L71932 | -75 | 5.3 | TTGATAAAATTATCACAA |
| Streptococcus agalactiae 2603V/R | SAG1100 | -36 | 4.5 | TAATAAAATTTTTAACAA |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1050 | -31 | 4.4 | TAGTTGCATATTTCACAA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1228 | -54 | 4.7 | TAGTTGATTTTTTCACAA |
| Streptococcus mitis B6 | smi_1188 | -57 | 5 | TTGTTGATTTTTTCACAA |
| Streptococcus mutans UA159 | SMU.1053 | -117 | 4.4 | TTGTTATAAAAAAAACTA |
| -58 | 4.5 | ATGTTGCATTTTTCACAA | ||
| Streptococcus pneumoniae TIGR4 | SP_1090 | -57 | 5 | TTGTTGATTTTTTCACAA |
| Streptococcus pyogenes M1 GAS | SPy1120 | -76 | 4.5 | ATGTTGCATTTTTCACAA |
| Streptococcus sanguinis SK36 | SSA_1216 | -55 | 4.7 | TAGTTGATTTTTTCACAA |
| Streptococcus suis 05ZYH33 | SSU05_1069 | -100 | 4.5 | CTGTTGATTTTTTCACAA |
| Streptococcus thermophilus CNRZ1066 | str1463 | -39 | 4.6 | TTGTTGCAATCTTCACAA |
| Streptococcus uberis 0140J | SUB0845 | -52 | 4.4 | TTGTTACAATAGTAACAT |
|
Position: -94
Score: 5.2 Sequence: TTGTGAAAATAATCTCAA
Locus tag: SpneCDC1_010100003265
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| SpneCDC1_010100003265 | -94 | 5.2 | TTGTGAAAATAATCTCAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: gapN | ||||
| Ortholog function: Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9) | ||||
| Streptococcus pneumoniae TIGR4 | SP_1119 | -94 | 5.2 | TTGTGAAAATAATCTCAA |
| Streptococcus sanguinis SK36 | SSA_0774 | -91 | 4.5 | TTGTGAAAAAATTCTTTA |
|
Position: -193
Score: 4.4 Sequence: AAGTTAGAATTTTCACAA
Locus tag: SpneCDC1_010100007028
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| SpneCDC1_010100007028 | -193 | 4.4 | AAGTTAGAATTTTCACAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: noxE | ||||
| Ortholog function: NADH oxidase (EC 1.6.99.3) | ||||
| Streptococcus agalactiae 2603V/R | SAG0958 | -165 | 4.3 | TTGTGAATTTGTGAAAAA |
| -59 | 4.7 | TTGTGAATAATGTTATAA | ||
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0909 | -23 | 4.6 | TTGTGAAATGAGGAACAA |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1023 | -81 | 4.3 | TTGTGAAATGAGGAACAT |
| Streptococcus pyogenes M1 GAS | SPy1150 | -23 | 4.6 | TTGTGAAATGAGGAACAA |
| Streptococcus thermophilus CNRZ1066 | str1281 | -91 | 4.6 | TTGTTCAAAAAGTAACAA |
| Streptococcus uberis 0140J | SUB0877 | -170 | 4.6 | TTGTGAATTTATGAACTA |
| -24 | 4.7 | TTGTGAAAAGAGGAACAA | ||
|
Position: -114
Score: 4.3 Sequence: TTGTTACTCTTTTCTCAA
Locus tag: SpneCDC1_010100007213
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| SpneCDC1_010100007213 | -114 | 4.3 | TTGTTACTCTTTTCTCAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: pncB | ||||
| Ortholog function: Nicotinate phosphoribosyltransferase (EC 2.4.2.11) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1202 | -218 | 4 | TTGTAGTATAAAAAACAT |
| Lactococcus lactis subsp. lactis Il1403 | L107468 | -181 | 3.9 | TTGTAGTACAAAAAACAT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1714 | -39 | 4.7 | ATGTTATAATAGTAACAA |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1574 | -39 | 4.3 | ATGGTATAATAATAACAA |
| Streptococcus mitis B6 | smi_1492 | -114 | 4.3 | TTGTTACTCTTTTCTCAA |
| Streptococcus mutans UA159 | SMU.464 | -265 | 4.3 | GTGTTATAATAGTAACAA |
| Streptococcus pneumoniae TIGR4 | SP_1421 | -114 | 4.3 | TTGTTACTCTTTTCTCAA |
| Streptococcus pyogenes M1 GAS | SPy1653 | -39 | 4.7 | ATGTTATAATAGTAACAA |
|
Position: -55
Score: 4.2 Sequence: AAGTTACTCTTTTCACAA
Locus tag: SpneCDC1_010100007913
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| SpneCDC1_010100007913 | -55 | 4.2 | AAGTTACTCTTTTCACAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: gap | ||||
| Ortholog function: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) | ||||
| Streptococcus agalactiae 2603V/R | SAG1768 | -76 | 4.4 | AAGTTAATCTTTTCACAT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1936 | -78 | 4.7 | AAGTTAATCTTTTCACAA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0207 | -158 | 4 | ATTTGAAAGAATGAACAA |
| Streptococcus mutans UA159 | SMU.360 | -81 | 4.7 | AAGTTAATCTTTTCACAA |
| Streptococcus pyogenes M1 GAS | SPy0274 | -79 | 4.7 | AAGTTAATCTTTTCACAA |
| Streptococcus sanguinis SK36 | SSA_2108 | -157 | 4.8 | TAGTGAAAGAATTCATAA |
| Streptococcus thermophilus CNRZ1066 | str1788 | -50 | 4.7 | AAGTTAATCTTTTCACAA |
| Streptococcus uberis 0140J | SUB1630 | -78 | 4.7 | AAGTTAATCTTTTCACAA |
|
Position: -190
Score: 5.1 Sequence: TTGAAATAAATTTCACAA
Position: -140
Score: 5.1 Sequence: ATGAGAAAAGTTTCACAA
Position: -96
Score: 4.6 Sequence: TTATGAAACTGTTTACAA
Position: -52
Score: 5.8 Sequence: TTGTGAAAAAATTAACAA
Locus tag: SpneCDC1_010100007973
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| SpneCDC1_010100007973 | -190 | 5.1 | TTGAAATAAATTTCACAA | |
| -140 | 5.1 | ATGAGAAAAGTTTCACAA | ||
| -96 | 4.6 | TTATGAAACTGTTTACAA | ||
| -52 | 5.8 | TTGTGAAAAAATTAACAA | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: adhE | ||||
| Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10) | ||||
| Streptococcus agalactiae 2603V/R | SAG0053 | -113 | 5.2 | TTGAAAAAAAGTTCACAA |
| -90 | 5.5 | TTGTGAAACTATTTACAA | ||
| -35 | 5.6 | TTGTGAAACATTTAACAA | ||
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0061 | -112 | 5.2 | TTGAAAAAAACTTCACAA |
| -89 | 5.4 | TTGTGAAATGATTTACAA | ||
| -34 | 5.5 | TTGTGAAACTTTTAACAA | ||
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0043 | -112 | 5 | TTGAAAAAAACATCACAA |
| -89 | 5.4 | TTGTGAAATGATTTACAA | ||
| -34 | 5.5 | TTGTGAAACTTTTAACAA | ||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0113 | -140 | 5.1 | TTGAAATATATTTCACAA |
| -51 | 5.8 | TTGTGAAAAAATTAACAA | ||
| Streptococcus mitis B6 | smi_0231 | -209 | 4.5 | TTGTGAAATAAAAAATAT |
| -191 | 5.1 | TTGAAATAATTTTCACAA | ||
| -141 | 5.4 | ATGAGAAAAATTTCACAA | ||
| -97 | 4.6 | TTATGAAACTGTTTACAA | ||
| -53 | 5.8 | TTGTGAAAAAATTAACAA | ||
| Streptococcus pneumoniae TIGR4 | SP_2026 | -208 | 4.5 | TTGTGAAATAAAAAATAT |
| -190 | 5.1 | TTGAAATAAATTTCACAA | ||
| -140 | 5.1 | ATGAGAAAAGTTTCACAA | ||
| -96 | 4.6 | TTATGAAACTGTTTACAA | ||
| -52 | 5.8 | TTGTGAAAAAATTAACAA | ||
| Streptococcus sanguinis SK36 | SSA_0068 | -226 | 4.3 | ATGTGAAATCTTTAAAAT |
| -156 | 5 | TTGTTATGTATTTCACAA | ||
| -67 | 5.7 | TTGTGAAATATTTAACAA | ||
| Streptococcus suis 05ZYH33 | SSU05_0280 | -129 | 4.5 | TTGGGGAAAAGTTAACAA |
| Streptococcus uberis 0140J | SUB0063 | -116 | 5.2 | TTGAAAAAAAGTTCACAA |
| -93 | 5.5 | TTGTGAAACTATTTACAA | ||
| -38 | 5.5 | TTGTGAAACTTTTAACAA | ||
|
Position: -96
Score: 5 Sequence: AAGTTAAAAAAATCACAA
Locus tag: SpneCDC1_010100008128
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| SpneCDC1_010100008128 | -96 | 5 | AAGTTAAAAAAATCACAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: adhB2 | ||||
| Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent | ||||
| Streptococcus mitis B6 | smi_0203 | -95 | 5 | AAGTTAAAAAAATCACAA |
| Streptococcus pneumoniae TIGR4 | SP_2055 | -96 | 5 | AAGTTAAAAAAATCACAA |
|
Position: -114
Score: 5.1 Sequence: TTGTGATATACTTCACAT
Locus tag: SpneCDC1_010100008356
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| SpneCDC1_010100008356 | -114 | 5.1 | TTGTGATATACTTCACAT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: adhB1 | ||||
| Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent | ||||
| Streptococcus agalactiae 2603V/R | SAG0054 | -118 | 4.4 | TTAAGAATATTTTCAAAA |
| -73 | 4.8 | TTGTGAAGAATAATACAA | ||
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0062 | -76 | 5.1 | TTGTGAAAAGATATACAA |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0046 | -80 | 5.1 | TTGTGAAAAAGTATACAA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0565 | -52 | 5.2 | TTGTGATATAATTAACAT |
| Streptococcus mitis B6 | smi_0275 | -114 | 5.1 | TTGTGATATACTTCACAT |
| Streptococcus pneumoniae TIGR4 | SP_0285 | -114 | 5.1 | TTGTGATATACTTCACAT |
| Streptococcus pyogenes M1 GAS | SPy0044 | -67 | 5 | TTGTGAAAAGATGTACAA |
| Streptococcus sanguinis SK36 | SSA_1917 | -51 | 5.2 | TTGTGATATAATTAACAT |
| Streptococcus suis 05ZYH33 | SSU05_0279 | -82 | 5.2 | TTGTGATATTCTTAACAA |