Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of SgaR regulog to Streptococcus pyogenes MGAS5005

Reference regulog properties
Source regulog: SgaR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: BglG
Regulation mode: repressor
Biological process: Ascorbate utilization
Effector: HPr, phosphocarrier protein; SgaB, ascorbate-specific PTS system EIIB component
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes MGAS5005
Orthologous TF(s) M5005_Spy_0155
Regulated genes 3
Built upon 19 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes MGAS5005
Locus tag Position Score Sequence
Position: -104
Score: 5
Sequence: AACACTTCTTTGTGTG
Locus tag: M5005_Spy_0148
M5005_Spy_0148 -104 5 AACACTTCTTTGTGTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: sgaT
Ortholog function: Ascorbate-specific PTS system, EIIC component
Streptococcus agalactiae 2603V/R SAG1815 -100 4.2 CACACTTAAGTGTGTA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2013 -104 5 AACACTTCTTTGTGTG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0168 -105 5.4 AACACATTACTGTGTG
Streptococcus gallolyticus UCN34 GALLO_2127 -100 5 CACACTTCCTTGTGTT
Streptococcus mutans UA159 SMU.270 -101 5.3 AACACTTGTATGTGTG
Streptococcus pyogenes M1 GAS SPy0174 -110 5 AACACTTCTTTGTGTG
Streptococcus sanguinis SK36 SSA_2093 -99 3.9 AACAGTCGCCTGTGTA
Streptococcus suis 05ZYH33 SSU05_2063 -93 5.2 AACACAAGCCTGTGCT
Streptococcus uberis 0140J SUB1727 -105 5.5 AACACAGAACTGTGTG
Position: -48
Score: 3.8
Sequence: AAAAATGGTGTGTGTT
Locus tag: M5005_Spy_0150
M5005_Spy_0150 -48 3.8 AAAAATGGTGTGTGTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: sgaC
Ortholog function: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)
Streptococcus agalactiae 2603V/R SAG1813 -100 4.2 CACACTTAAGTGTGTA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2011 -104 5 AACACTTCTTTGTGTG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0170 -105 5.4 AACACATTACTGTGTG
Streptococcus gallolyticus UCN34 GALLO_2125 -100 5 CACACTTCCTTGTGTT
Streptococcus mutans UA159 SMU.272 -101 5.3 AACACTTGTATGTGTG
Streptococcus pyogenes M1 GAS SPy0176 -110 5 AACACTTCTTTGTGTG
Streptococcus sanguinis SK36 SSA_2091 -99 3.9 AACAGTCGCCTGTGTA
Streptococcus suis 05ZYH33 SSU05_2061 -93 5.2 AACACAAGCCTGTGCT
Streptococcus uberis 0140J SUB1725 -105 5.5 AACACAGAACTGTGTG
Position: -95
Score: 5.6
Sequence: AACACAGATCTGTGTG
Locus tag: M5005_Spy_0156
M5005_Spy_0156 -95 5.6 AACACAGATCTGTGTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: sgaG
Ortholog function: Predicted L-ascorbate-6-phosphate lactonase (EC 3.1.1.-)
Streptococcus agalactiae 2603V/R SAG1800 -92 5.4 AACACATAAATGTGTG
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2006 -94 5.5 AACACAGAACTGTGTG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0175 -92 5.1 AACACAAGAGTGTGTG
Streptococcus mitis B6 smi_0226 -94 5.7 AACACAAACCTGTGTT
Streptococcus mutans UA159 SMU.290 -100 5.7 AACACAAGCTTGTGTT
Streptococcus pneumoniae TIGR4 SP_2031 -94 5.7 AACACAAACCTGTGTT
Streptococcus pyogenes M1 GAS SPy0182 -95 5.6 AACACAGATCTGTGTG
Streptococcus sanguinis SK36 SSA_2076 -96 5.8 AACACAGACCTGTGTT
Streptococcus suis 05ZYH33 SSU05_2055 -92 5.7 AACACAAGCCTGTGTT
Streptococcus uberis 0140J SUB1720 -92 5.3 AACACTTACATGTGTG
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