Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of CcpA regulog to Streptococcus pyogenes MGAS5005

Reference regulog properties
Source regulog: CcpA - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LacI
Regulation mode:
Biological process: Global catabolite repression
Effector: Fructose-1,6-bisphosphate; HPr, phosphocarrier protein
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes MGAS5005
Orthologous TF(s) M5005_Spy_0424
Regulated genes 81
Built upon 968 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes MGAS5005
Locus tag Position Score Sequence
Position: -208
Score: 4.7
Sequence: AAGAAAGCGGTTTCAG
Locus tag: M5005_Spy_0039
M5005_Spy_0039 -208 4.7 AAGAAAGCGGTTTCAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhE
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10)
Streptococcus agalactiae 2603V/R SAG0053 -146 5.1 ATTAAAGCGCTTTCAA
Streptococcus mitis B6 smi_0231 -95 4.4 ATGAAACTGTTTACAA
-73 3.7 AATAATGCGTTATAAT
Streptococcus pneumoniae TIGR4 SP_2026 -94 4.4 ATGAAACTGTTTACAA
-72 3.7 AATAATGCGTTATAAT
Streptococcus sanguinis SK36 SSA_0068 -109 4 GTGAAAGTGTTTACAA
Position: -44
Score: 4.6
Sequence: TTGTAACCGATTACAA
Locus tag: M5005_Spy_0040
M5005_Spy_0040 -44 4.6 TTGTAACCGATTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhB1
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1)
Lactococcus lactis subsp. cremoris SK11 LACR_1990 -44 4.6 AAGAATGCGTTTACAA
Lactococcus lactis subsp. lactis Il1403 L55758 -43 5.1 AAGAAAGCGTTTACAA
Streptococcus agalactiae 2603V/R SAG0054 -49 4.9 ATGTAAACGATTACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0062 -52 4.5 TTGTAAACGGTTACAG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0046 -56 4.5 TTGTAAACGGTTGCAA
Streptococcus mitis B6 smi_0275 -130 4.1 TGGAAAAGGCTTTCTT
Streptococcus pneumoniae TIGR4 SP_0285 -130 4.1 TGGAAAAGGCTTTCTT
Streptococcus pyogenes M1 GAS SPy0044 -44 4.6 TTGTAACCGATTACAA
Streptococcus sanguinis SK36 SSA_1917 -78 4.6 TTGTAAACGTTTCCTA
Streptococcus suis 05ZYH33 SSU05_0279 -197 4.8 AAGAAAACGCTTCCAT
Streptococcus thermophilus CNRZ1066 str0880 -50 4.3 ATGTAAGCGTTGATAT
Streptococcus thermophilus CNRZ1066 str0881 -50 4.3 ATGTAAGCGTTGATAT
Streptococcus thermophilus CNRZ1066 str0882 -50 4.3 ATGTAAGCGTTGATAT
Position: -28
Score: 4.6
Sequence: CAGAAAACGATTTCAA
Locus tag: M5005_Spy_0094
M5005_Spy_0094 -28 4.6 CAGAAAACGATTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ackA
Ortholog function: Acetate kinase (EC 2.7.2.1)
Lactococcus lactis subsp. cremoris SK11 LACR_2294 -30 4.3 AATAAAACGCATACAT
Lactococcus lactis subsp. cremoris SK11 LACR_2295 -129 4.4 ATGCAAACGCTTTTTA
Lactococcus lactis subsp. lactis Il1403 L0224 -30 4.3 AATAAAACGCATACAT
Lactococcus lactis subsp. lactis Il1403 L73818 -129 4.5 TTGAAAAGGTTTTTAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0142 -28 4.9 TAGAAAACGATTTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0124 -28 4.6 CAGAAAACGATTTCAA
Streptococcus gallolyticus UCN34 GALLO_0095 -25 4.4 ATGAAAGCGCTTTAGA
Streptococcus gordonii str. Challis substr. CH1 SGO_1916 -26 4.6 CTGAAAACGCTTAAAA
Streptococcus mitis B6 smi_0214 -90 5 ATGAAAACGCTTAAAA
Streptococcus mutans UA159 SMU.1978 -28 4.3 TCGTAAACGATTTCAT
Streptococcus pneumoniae TIGR4 SP_2044 -30 4.9 TTGAAAACGCTTAAAA
Streptococcus pyogenes M1 GAS SPy0109 -28 4.6 CAGAAAACGATTTCAA
Streptococcus sanguinis SK36 SSA_0192 -26 4.6 TTGAAAACGCTTAAAG
3 4.3 TCGAAAACGATTTCTA
Streptococcus suis 05ZYH33 SSU05_0135 -27 4.5 AGGAAAACGCTTTAAA
Streptococcus thermophilus CNRZ1066 str1857 0 4.9 TTGAAAGCGTTTTATA
Streptococcus uberis 0140J SUB0126 -28 4.6 CAGAAAACGATTTCAA
Position: -160
Score: 4.9
Sequence: ATGAAAACGCTGTCAT
Locus tag: M5005_Spy_0116
M5005_Spy_0116 -160 4.9 ATGAAAACGCTGTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: atoE
Ortholog function: Short chain fatty acids transporter
Streptococcus pyogenes M1 GAS SPy0137 -190 4.9 ATGAAAACGCTGTCAT
Position: -37
Score: 4.5
Sequence: ATGTAAGCGTTTCAAT
Locus tag: M5005_Spy_0119
M5005_Spy_0119 -37 4.5 ATGTAAGCGTTTCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: atoB
Ortholog function: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9)
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1437 -80 4.2 TTGCAAACGCTTTTAG
-39 5.1 TAGAAAGCGCTTTCTA
Streptococcus pyogenes M1 GAS SPy0140 -37 4.5 ATGTAAGCGTTTCAAT
Position: -75
Score: 5.1
Sequence: TTTAAAACGCTTTCAT
Locus tag: M5005_Spy_0148
M5005_Spy_0148 -75 5.1 TTTAAAACGCTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: sgaT
Ortholog function: Ascorbate-specific PTS system, IIC component
Streptococcus agalactiae 2603V/R SAG1815 -71 4.9 TTTAAAACGCTTACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2013 -171 4 TTTAAAGAGTTTTAAA
-75 5.1 TTTAAAACGCTTTCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0168 -76 5 TTTAAAACGCTTACAT
Streptococcus gallolyticus UCN34 GALLO_2127 -71 4.3 TTGTTTGCGCTTACAT
Streptococcus mitis B6 smi_0219 -60 4.4 TTGTTTACGCTTTCAA
Streptococcus mutans UA159 SMU.270 -72 4.2 TTGTTAGCATTTTCAA
Streptococcus pyogenes M1 GAS SPy0174 -81 5.1 TTTAAAACGCTTTCAT
Streptococcus sanguinis SK36 SSA_2093 -70 4.6 TTGTTATCGCTTTCAA
Streptococcus suis 05ZYH33 SSU05_2063 -64 4 TTGTTTCCGCTTACAT
Streptococcus uberis 0140J SUB1727 -76 4.5 TTTAAAACGCTTTCAC
Position: -52
Score: 4.3
Sequence: TAGAAAAGGTTATCAT
Locus tag: M5005_Spy_0185
M5005_Spy_0185 -52 4.3 TAGAAAAGGTTATCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pgi
Ortholog function: Glucose-6-phosphate isomerase (EC 5.3.1.9)
Lactococcus lactis subsp. cremoris SK11 LACR_2470 -148 4 AAATAAGTGCTTACAT
Lactococcus lactis subsp. lactis Il1403 L0012 -148 4.7 AAATAAGCGCTTACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1988 -120 4.8 TTGAAAACCTTTTCAA
-51 4.3 TAGAAAAGGTTATCAT
Streptococcus gallolyticus UCN34 GALLO_2098 -105 4.2 TGGTAAACGCTTTATT
Streptococcus gordonii str. Challis substr. CH1 SGO_0154 -85 4.6 TTGGAAGCGTTTTAAA
-44 3.8 CGTAAAGCGTTATCAT
Streptococcus mitis B6 smi_0157 -44 4 AAGTAAGCGTTATGAT
Streptococcus mutans UA159 SMU.307 -85 4.9 ATGAAAGCGTTTTATA
Streptococcus pyogenes M1 GAS SPy0215 -121 4.2 ACGAAAACCTTTTCAA
-52 4.3 TAGAAAAGGTTATCAT
Streptococcus sanguinis SK36 SSA_2183 -52 4.6 TTGGAAGCGTTTTAAA
-11 4.1 ATGAAAGCGATATGAT
Streptococcus suis 05ZYH33 SSU05_2051 32 3.9 GATAAAGCGTTATCAT
Position: -81
Score: 5
Sequence: TTGAAAGCGCTTTATT
Locus tag: M5005_Spy_0212
M5005_Spy_0212 -81 5 TTGAAAGCGCTTTATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nanE
Ortholog function: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1959 -81 4.9 TTGAAAACGCTTTATT
Streptococcus pyogenes M1 GAS SPy0251 -81 5 TTGAAAGCGCTTTATT
Position: -40
Score: 4.8
Sequence: ATGTAAGCGCTAACAA
Locus tag: M5005_Spy_0340
M5005_Spy_0340 -40 4.8 ATGTAAGCGCTAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: lctO
Ortholog function: Lactate 2-monooxygenase (EC 1.13.12.4)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0467 -43 4.5 TTGTAAGCGCTCACAA
Streptococcus mitis B6 smi_1435 -33 4.5 AAGCAAACGCTTACTT
Streptococcus pneumoniae TIGR4 SP_0715 -34 4.5 AAGCAAACGCTTACTT
Streptococcus pyogenes M1 GAS SPy0414 -34 4.8 ATGTAAGCGCTAACAA
Position: -117
Score: 4.3
Sequence: TTGTAACCACTTTCAA
Position: -84
Score: 4.6
Sequence: TTGAAAAAGTTTTCAA
Locus tag: M5005_Spy_0423
M5005_Spy_0423 -117 4.3 TTGTAACCACTTTCAA
-84 4.6 TTGAAAAAGTTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pepQ
Ortholog function: Xaa-Pro dipeptidase (EC 3.4.13.9)
Lactococcus lactis subsp. cremoris SK11 LACR_1813 -136 4.4 CTGTAAACCTTTTCAA
Lactococcus lactis subsp. lactis Il1403 L96847 -173 4.1 ATGAAAACCATTTTTA
-137 4.4 CTGTAAACCTTTTCAA
Streptococcus agalactiae 2603V/R SAG0706 -151 4.3 TTGGAAACACTTTCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0544 -151 4 AAAATTACGCTTTCAA
-117 4.3 TTGTAACCACTTTCAA
-84 4.6 TTGAAAAAGTTTTCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0771 -142 4.5 AAAATAACGTTTTCAT
-98 4.3 TTGGAAACACTTTCAA
Streptococcus mutans UA159 SMU.1592 -106 4.8 TTGAAAACACTTTCAA
Streptococcus pyogenes M1 GAS SPy0513 -117 4.3 TTGTAACCACTTTCAA
-84 4.6 TTGAAAAAGTTTTCAA
Streptococcus sanguinis SK36 SSA_1577 -97 4.6 TTGTAAACACTTTCAA
Streptococcus suis 05ZYH33 SSU05_1373 -135 4.5 TTGAAACCACTTTCAA
Streptococcus thermophilus CNRZ1066 str0629 -134 3.8 TATTCATCGCTTACAA
Streptococcus uberis 0140J SUB0535 -115 4.5 TTGAAACCACTTTCAA
Position: -105
Score: 4.6
Sequence: TTGAAAACTTTTTCAA
Position: -72
Score: 4.3
Sequence: TTGAAAGTGGTTACAA
Locus tag: M5005_Spy_0424
M5005_Spy_0424 -105 4.6 TTGAAAACTTTTTCAA
-72 4.3 TTGAAAGTGGTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ccpA
Ortholog function: Carbon catabolism global transcriptional regulator CcpA, LacI family
Lactococcus lactis subsp. cremoris SK11 LACR_1812 -93 4.4 TTGAAAAGGTTTACAG
Lactococcus lactis subsp. lactis Il1403 L0143 -93 4.4 TTGAAAAGGTTTACAG
-57 4.1 TAAAAATGGTTTTCAT
Streptococcus agalactiae 2603V/R SAG0707 -74 4.3 TTGAAAGTGTTTCCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0545 -105 4.6 TTGAAAACTTTTTCAA
-72 4.3 TTGAAAGTGGTTACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1410 -105 4.6 TTGAAAACTTTTTCAA
-72 4.3 TTGAAAGTGGTTACAA
Streptococcus gallolyticus UCN34 GALLO_1582 -122 4.7 AATTAAACGCTTACAA
-71 4.3 TTGAAAGTGTTTCCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0773 -82 4.3 TTGAAAGTGTTTCCAA
-38 4.5 ATGAAAACGTTATTTT
Streptococcus mitis B6 smi_0284 -113 4.6 TTGAAAGTGTTTACAA
Streptococcus mutans UA159 SMU.1591 -72 4.8 TTGAAAGTGTTTTCAA
Streptococcus pneumoniae TIGR4 SP_1999 -150 4.6 TTGAAAGTGTTTACAA
Streptococcus pyogenes M1 GAS SPy0514 -105 4.6 TTGAAAACTTTTTCAA
-72 4.3 TTGAAAGTGGTTACAA
Streptococcus sanguinis SK36 SSA_1576 -81 4.6 TTGAAAGTGTTTACAA
Streptococcus thermophilus CNRZ1066 str0630 -41 4.8 TTGAAAGTGTTTTCAA
Streptococcus uberis 0140J SUB0536 -72 4.5 TTGAAAGTGGTTTCAA
Position: -16
Score: 4.1
Sequence: ATGAAAGGGATTTTTT
Locus tag: M5005_Spy_0438
M5005_Spy_0438 -16 4.1 ATGAAAGGGATTTTTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: rnc
Ortholog function: Ribonuclease III (EC 3.1.26.3)
Streptococcus agalactiae 2603V/R SAG0723 -94 4.6 AAGGAAACGTTTTCTT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0572 -16 4.1 ATGAAAGGGGTTTTTT
Streptococcus gallolyticus UCN34 GALLO_1551 -90 4 GAAAAAGCGTTTTAAT
-56 4.1 AAAGAAACGTTTTAAT
Streptococcus pyogenes M1 GAS SPy0531 -16 4.1 ATGAAAGGGATTTTTT
Streptococcus suis 05ZYH33 SSU05_1192 -142 4.2 ATGTAAATGTTTGCAA
Streptococcus suis 05ZYH33 SSU05_1191 -142 4.2 ATGTAAATGTTTGCAA
Position: -210
Score: 4
Sequence: TTGAAAACGCTTGACA
Position: -173
Score: 4.2
Sequence: ATTAAAGCGTTCTCAG
Position: 7
Score: 3.9
Sequence: TTAAACGCGTTTTAAA
Locus tag: M5005_Spy_0474
M5005_Spy_0474 -210 4 TTGAAAACGCTTGACA
-173 4.2 ATTAAAGCGTTCTCAG
7 3.9 TTAAACGCGTTTTAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: licT
Ortholog function: Beta-glucoside bgl operon transcriptional antiterminator, BglG family
Streptococcus agalactiae 2603V/R SAG0789 -171 4 ATTAAGACGTTTTCAG
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0582 -173 4.2 ATTAAAGCGTTCTCAG
7 3.9 TTAAACGCGTTTTAAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1377 -174 4.3 ATGAAAACGTTATTAG
Streptococcus pneumoniae TIGR4 SP_0576 -169 4.3 ATAAAAACGGTTACAG
Streptococcus pyogenes M1 GAS SPy0571 -173 4.2 ATTAAAGCGTTCTCAG
Streptococcus suis 05ZYH33 SSU05_1491 -104 4 TTGAAAATGGTTACAG
-36 4 ATGTTATCGCTTTAAG
Position: -99
Score: 4.3
Sequence: TTTGAACCGTTTTCAT
Locus tag: M5005_Spy_0524
M5005_Spy_0524 -99 4.3 TTTGAACCGTTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kduD
Ortholog function: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127)
Streptococcus agalactiae 2603V/R SAG1904 -59 4.8 ATTATAGCGCTTTCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0650 -99 4.3 TTTGAACCGTTTTCAT
Streptococcus pyogenes M1 GAS SPy0636 -99 4.3 TTTGAACCGTTTTCAT
Streptococcus suis 05ZYH33 SSU05_1225 -85 3.9 TAAAAACCGTTGACAA
-42 4.4 TTGTAAACGCTTTACA
Position: -131
Score: 4.6
Sequence: TTGACACCGTTTTCAT
Locus tag: M5005_Spy_0534
M5005_Spy_0534 -131 4.6 TTGACACCGTTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: butA
Ortholog function: 2,3-butanediol dehydrogenase, S-alcohol forming, (R)-acetoin-specific (EC 1.1.1.4) / Acetoin (diacetyl) reductase (EC 1.1.1.5)
Lactococcus lactis subsp. lactis Il1403 L118271 -129 4.9 AAGAAAACGCTTTAAA
Streptococcus agalactiae 2603V/R SAG0523 -131 4.6 TTGACACCGTTTTCAT
Streptococcus gallolyticus UCN34 GALLO_0485 -46 4.6 TTGTAAGCGCTATAAT
Streptococcus thermophilus CNRZ1066 str0909 -124 4.9 TTGACAACGTTTTCAT
Streptococcus thermophilus CNRZ1066 str0910 -124 4.9 TTGACAACGTTTTCAT
Position: -48
Score: 4
Sequence: TAGAAATCGATATAAT
Locus tag: M5005_Spy_0555
M5005_Spy_0555 -48 4 TAGAAATCGATATAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yuel
Ortholog function: Conserved hypothetical protein
Streptococcus agalactiae 2603V/R SAG0627 -117 4 GTGAAACCGCTTTATT
Streptococcus gordonii str. Challis substr. CH1 SGO_1427 -107 4.2 AAATAAGCGTTTTTTT
Streptococcus mitis B6 smi_1160 -55 4.7 AAGTAATCGCTTTCTT
Streptococcus pneumoniae TIGR4 SP_1127 -55 4.7 AAGTAATCGCTTTCTT
Streptococcus pyogenes M1 GAS SPy0729 -48 4 TAGAAATCGATATAAT
Streptococcus sanguinis SK36 SSA_0885 -99 4.5 AAGAAAACGATTCCAA
Streptococcus thermophilus CNRZ1066 str0634 -59 4.1 ATGAAAAGGAATTCAA
Position: -194
Score: 4
Sequence: ATTATATCGATTTCTA
Locus tag: M5005_Spy_0556
M5005_Spy_0556 -194 4 ATTATATCGATTTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: eno
Ortholog function: Enolase (EC 4.2.1.11)
Streptococcus agalactiae 2603V/R SAG0628 -96 4 AATAAAGCGGTTTCAC
Streptococcus gordonii str. Challis substr. CH1 SGO_1426 -63 4.2 AAAAAAACGCTTATTT
Streptococcus mitis B6 smi_1159 -124 4.7 AAGAAAGCGATTACTT
Streptococcus pneumoniae TIGR4 SP_1128 -124 4.7 AAGAAAGCGATTACTT
Streptococcus pyogenes M1 GAS SPy0731 -194 4 ATTATATCGATTTCTA
Streptococcus sanguinis SK36 SSA_0886 -125 4.5 TTGGAATCGTTTTCTT
Streptococcus suis 05ZYH33 SSU05_1503 -115 4 AGGAAGGCGTTTACAT
Streptococcus thermophilus CNRZ1066 str0635 -165 4.1 TTGAATTCCTTTTCAT
Position: -188
Score: 4.6
Sequence: AAGAAAGGGTTTACAT
Locus tag: M5005_Spy_0562
M5005_Spy_0562 -188 4.6 AAGAAAGGGTTTACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: sagA
Ortholog function: Streptolysin S precursor
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0705 -181 4.6 AAGAAAGGGTTTACAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0490 -209 4.5 AAGAAAGCATTTACAT
Streptococcus pyogenes M1 GAS SPy0738 -188 4.6 AAGAAAGGGTTTACAT
Position: 19
Score: 4.1
Sequence: AAATTAGCGCTTTAAT
Locus tag: M5005_Spy_0579
M5005_Spy_0579 19 4.1 AAATTAGCGCTTTAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: atpA
Ortholog function: ATP synthase alpha chain (EC 3.6.3.14)
Lactococcus lactis subsp. cremoris SK11 LACR_1935 -135 4.3 TATCAAACGCTTACAA
Streptococcus agalactiae 2603V/R SAG0861 -93 4.5 ATGAAAACGTAATCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1544 -96 4.6 TTAAAATCGCTTACAA
Streptococcus mitis B6 smi_1311 -93 4.5 CATTAAACGCTTTCAA
Streptococcus mutans UA159 SMU.1530 -161 4.1 TTAAAAGCGTCTTCTA
Streptococcus pneumoniae TIGR4 SP_1510 -93 4.3 TATTAAACGCTTCCAA
Streptococcus sanguinis SK36 SSA_0786 -194 4.5 TTTTAATCGCTTTCTT
-95 4.4 CAAAAAACGCTTACAA
Streptococcus suis 05ZYH33 SSU05_1174 -92 4.7 AATTAAACGCTTACAA
Streptococcus uberis 0140J SUB0670 -94 4.4 AAGAAAGCGTAATCAA
Position: -60
Score: 4.7
Sequence: TTGTAAACGATTTCAG
Locus tag: M5005_Spy_0660
M5005_Spy_0660 -60 4.7 TTGTAAACGATTTCAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: fruR
Ortholog function: Fructose utilization transcriptional regulator FruR, DeoR family
Lactococcus lactis subsp. cremoris SK11 LACR_1031 -25 4.2 TTGTAAACGAATTCAG
Lactococcus lactis subsp. lactis Il1403 L0031 -25 4.2 TTGTAAACGAATTCAG
Streptococcus agalactiae 2603V/R SAG1348 -30 4.7 TTGCAAACGATTTCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0811 -60 4.1 CTGTAACCGATTTCAG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1106 -62 4.4 CTGTAAACGATTTCAG
Streptococcus gallolyticus UCN34 GALLO_1319 -30 4.4 CTGTAAACGATTTCAG
Streptococcus gordonii str. Challis substr. CH1 SGO_1111 -27 4 ATGTAAGCTGTTTCAG
Streptococcus mutans UA159 SMU.870 22 4.4 GTGTAAACGATTTCAA
Streptococcus pyogenes M1 GAS SPy0853 -60 4.7 TTGTAAACGATTTCAG
Streptococcus suis 05ZYH33 SSU05_0822 14 4.2 TTGTAAACGGTTGCAG
Streptococcus thermophilus CNRZ1066 str0399 -109 3.8 AGGTTAGCGTTTTATA
-27 4.5 TTGTAAACGATTACAG
Streptococcus uberis 0140J SUB0748 -60 4.4 TTGTAACCGATTTCAG
Position: -116
Score: 4.9
Sequence: TTTAAATCGCTTTCAT
Locus tag: M5005_Spy_0678
M5005_Spy_0678 -116 4.9 TTTAAATCGCTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yhcR
Ortholog function: 5'-nucleotidase (EC 3.1.3.5)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0825 -116 4.9 TTTAAAGCGATTTCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1088 -135 4.6 TTTTAAACGTTTTCAG
Streptococcus pyogenes M1 GAS SPy0872 -116 4.9 TTTAAATCGCTTTCAT
Position: -171
Score: 4
Sequence: AAGTAAGTGCTTATAT
Position: -61
Score: 4
Sequence: AAGTTGGCGCTTTCAT
Locus tag: M5005_Spy_0695
M5005_Spy_0695 -171 4 AAGTAAGTGCTTATAT
-61 4 AAGTTGGCGCTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: rpiA
Ortholog function: Ribose 5-phosphate isomerase A (EC 5.3.1.6)
Streptococcus agalactiae 2603V/R SAG1183 -110 4.6 AAGAAAATGTTTTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1165 -61 4.3 AAGTTTGCGCTTTCAT
Streptococcus gordonii str. Challis substr. CH1 SGO_1265 -120 4.3 AGGAAAATGCTTTCAT
Streptococcus pneumoniae TIGR4 SP_0828 -53 4.4 ATAAAAGCCTTTACAT
Streptococcus pyogenes M1 GAS SPy0889 -171 4 AAGTAAGTGCTTATAT
Streptococcus sanguinis SK36 SSA_1261 -66 4.7 AAGAAAACACTTTCAT
Streptococcus thermophilus CNRZ1066 str1121 -94 4.5 TTGATAGCCTTTTCAT
Position: -79
Score: 4.7
Sequence: TAGAAAGCGATTTAAT
Locus tag: M5005_Spy_0751
M5005_Spy_0751 -79 4.7 TAGAAAGCGATTTAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: acoA
Ortholog function: Acetoin dehydrogenase E1 component alpha-subunit (EC 1.2.4.-)
Streptococcus agalactiae 2603V/R SAG0878 -81 4.2 AAGAAAGCGGTTCAAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1250 -67 4.7 AAGAAAGCGATTTAAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1222 -90 3.9 TTAAAAAAGCTTTTAT
-67 4.5 AAGAAAGCGATTAAAA
Streptococcus gallolyticus UCN34 GALLO_0867 -99 5 TTTAAAACGTTTTCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1133 -63 4.4 TTGACAGGGTTTTCAT
Streptococcus mutans UA159 SMU.127 -51 4.1 TAGAAAGCGGTTCAAA
Streptococcus pyogenes M1 GAS SPy1026 -79 4.7 TAGAAAGCGATTTAAT
Streptococcus sanguinis SK36 SSA_1178 -63 3.8 TTGACAGTGCTTACAG
Streptococcus suis 05ZYH33 SSU05_1841 -36 4.2 AAGAAAACGGTTCAAT
Streptococcus thermophilus CNRZ1066 str1051 -96 4.2 ATGTAAGGCTTTTCAT
Streptococcus uberis 0140J SUB1103 -80 4.6 TAGAAAGCGGTTTTAA
Position: -97
Score: 4.2
Sequence: ATGTAAGGGTTTATAA
Locus tag: M5005_Spy_0757
M5005_Spy_0757 -97 4.2 ATGTAAGGGTTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: hyl
Ortholog function: Hyaluronate lyase precursor (EC 4.2.2.1)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0654 -99 4.3 TTTGAACCGTTTTCAT
Streptococcus pneumoniae TIGR4 SP_0314 -128 4.8 TAGAAACCGTTTACAA
Streptococcus pyogenes M1 GAS SPy1032 -97 4.2 ATGTAAGGGTTTATAA
Streptococcus suis 05ZYH33 SSU05_1215 -102 4.8 TATAAAACGCTTACAT
Streptococcus suis 05ZYH33 SSU05_1214 -102 4.8 TATAAAACGCTTACAT
Streptococcus suis 05ZYH33 SSU05_1213 -102 4.8 TATAAAACGCTTACAT
Streptococcus suis 05ZYH33 SSU05_1212 -102 4.8 TATAAAACGCTTACAT
Position: -119
Score: 5.1
Sequence: TTTAAAACGTTTTCAT
Locus tag: M5005_Spy_0780
M5005_Spy_0780 -119 5.1 TTTAAAACGTTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ptsA
Ortholog function: Predicted mannose/fructose-specific PTS system, IIA component
Streptococcus agalactiae 2603V/R SAG1951 -108 4.8 TTTAAACCGCTTTCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1215 -119 5.1 TTTAAAACGTTTTCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1187 -16 5 TTAAAAACGTTTTCAT
Streptococcus pyogenes M1 GAS SPy1057 -119 5.1 TTTAAAACGTTTTCAT
Position: -59
Score: 4.9
Sequence: TTGAAATCGATTTCAT
Locus tag: M5005_Spy_0790
M5005_Spy_0790 -59 4.9 TTGAAATCGATTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: gabD
Ortholog function: Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)
Streptococcus agalactiae 2603V/R SAG1124 -53 4.8 TTGTAATCGATTTCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1202 -56 4.9 TTGAAATCGATTTCAA
Streptococcus gallolyticus UCN34 GALLO_0925 -146 4.1 ACGATAGCGTTTACTT
-132 4.1 TTGAAACCGTTTCCTG
Streptococcus mutans UA159 SMU.2127 -57 4.8 TTGAAATCGGTTTCAA
Streptococcus pyogenes M1 GAS SPy1067 -59 4.9 TTGAAATCGATTTCAT
Streptococcus uberis 0140J SUB1058 -56 4.3 TTGAAATCGTTACCAA
Position: -41
Score: 4.7
Sequence: TTGAAAACCCTTTCTT
Locus tag: M5005_Spy_0834
M5005_Spy_0834 -41 4.7 TTGAAAACCCTTTCTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: adh
Ortholog function: Alcohol dehydrogenase, Zn-dependent (EC 1.1.1.1)
Streptococcus agalactiae 2603V/R SAG1637 -66 4.8 TTGTAACCGCTTTCTT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0045 -43 4.7 ATGTAATCGATTACAT
Streptococcus mitis B6 smi_0203 -59 4.7 TTGAAAAGGCTTACAA
Streptococcus pyogenes M1 GAS SPy1111 -83 4.7 TTGAAAACCCTTTCTT
Position: -168
Score: 4.7
Sequence: AAGAAAGGGTTTTCAA
Locus tag: M5005_Spy_0835
M5005_Spy_0835 -168 4.7 AAGAAAGGGTTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: aphA
Ortholog function: Class B acid phosphatase precursor (EC 3.1.3.2)
Streptococcus agalactiae 2603V/R SAG0635 -80 4.8 ATGATATCGCTTTCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1259 -80 4.8 ATGATATCGCTTTCAT
Streptococcus pyogenes M1 GAS SPy1113 -168 4.7 AAGAAAGGGTTTTCAA
-60 4.3 TTGAAACCGCTTTACT
Position: -123
Score: 4.2
Sequence: TTGGAAGCGTTATCAG
Locus tag: M5005_Spy_0873
M5005_Spy_0873 -123 4.2 TTGGAAGCGTTATCAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: ldh
Ortholog function: L-lactate dehydrogenase (EC 1.1.1.27)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0911 -123 3.9 CTGGAAGCGTTATCAG
Streptococcus gordonii str. Challis substr. CH1 SGO_1232 -116 4.6 CTAAAAACGTTTACAT
Streptococcus pneumoniae TIGR4 SP_1220 -117 4.3 ACTAAAACGTTTACAT
Streptococcus pyogenes M1 GAS SPy1151 -123 4.2 TTGGAAGCGTTATCAG
Streptococcus sanguinis SK36 SSA_1221 -114 4.3 GTAAAAACGTTTACAT
Streptococcus suis 05ZYH33 SSU05_1076 -113 4.6 ATGTAAACATTTTCAA
Streptococcus thermophilus CNRZ1066 str1280 -115 4.5 TTTAAAACGCTTTCAC
Position: -52
Score: 4.9
Sequence: TTATAAGCGCTTTCAT
Locus tag: M5005_Spy_0900
M5005_Spy_0900 -52 4.9 TTATAAGCGCTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: citN
Ortholog function: Mg2+/citrate complex secondary transporter
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0992 -56 4.6 TTCTAAGCGCTTTCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0988 -54 4.4 TTGCGAACGCTTTCAT
Streptococcus mutans UA159 SMU.1013c -160 3.9 TTTAAAATGTTTTTTT
-115 5 TTTTAAGCGCTTTCAT
Streptococcus pyogenes M1 GAS SPy1180 -122 4 TAAAAATGGTTTTCAA
-52 4.9 TTATAAGCGCTTTCAT
Position: -35
Score: 4.9
Sequence: ATGAAAGCGTTTATAA
Locus tag: M5005_Spy_0938
M5005_Spy_0938 -35 4.9 ATGAAAGCGTTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pgm
Ortholog function: Phosphoglucomutase (EC 5.4.2.2)
Streptococcus agalactiae 2603V/R SAG1066 -35 4.9 ATGAAAGCGTTTATAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1043 -34 4.7 ATGAAAGCGGTTAAAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0941 0 4.7 ATGAAAGCGGTTAAAA
Streptococcus gallolyticus UCN34 GALLO_1123 -39 4.6 ATGAAAGCGTTTAGAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1215 -83 4.4 ATGAAAGCGATTAGAT
Streptococcus mitis B6 smi_1173 -40 4.5 ATGTAAACGATTAAAA
Streptococcus mutans UA159 SMU.1077 -55 4.7 ATGAAAGCGGTTAAAT
Streptococcus pyogenes M1 GAS SPy1224 -35 4.9 ATGAAAGCGTTTATAA
Streptococcus sanguinis SK36 SSA_1204 -137 4 ATTTCATCGTTTTCTA
Streptococcus suis 05ZYH33 SSU05_0686 -40 4.8 ATGAAAGCGTTTAATA
Streptococcus thermophilus CNRZ1066 str0787 -33 4.8 ATGTAAGCGTTTAAAA
Streptococcus uberis 0140J SUB0946 -34 4.5 ATGAAAGCGGTTAATA
Position: -223
Score: 4.4
Sequence: TTGAAATGGTTTACAA
Position: -32
Score: 4.2
Sequence: ATGTAAGCACTGTCAA
Locus tag: M5005_Spy_0945
M5005_Spy_0945 -223 4.4 TTGAAATGGTTTACAA
-32 4.2 ATGTAAGCACTGTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: coaA
Ortholog function: Pantothenate kinase (EC 2.7.1.33)
Lactococcus lactis subsp. cremoris SK11 LACR_1533 -68 4.1 TTTAATACGCTTACAG
Lactococcus lactis subsp. lactis Il1403 L66222 -68 4.1 TTTAATACGCTTACAG
Streptococcus agalactiae 2603V/R SAG0951 -60 4.5 TTGAAACGGTTTTCAA
-29 3.9 TTATAATAGCTTTCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1052 -199 3.9 TTTTAAAGGTTTCCAA
-32 4.2 ATGTAAGCACTGTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0931 -223 4.4 TTGAAATGGTTTACAA
Streptococcus gallolyticus UCN34 GALLO_1139 -69 4.4 TTGTAACGGTTTTCAA
-47 3.8 ATTAAAGTGCTATAAT
Streptococcus gordonii str. Challis substr. CH1 SGO_1077 -74 4.1 TGTAAATCGTTTACAT
Streptococcus mitis B6 smi_0883 -64 4.5 AAGAAACCGCTTTATT
Streptococcus mutans UA159 SMU.1126 -52 4.5 TTGAAACGGTTTTCAA
Streptococcus pneumoniae TIGR4 SP_0839 -64 4.5 AAGAAACCGCTTTATT
Streptococcus pyogenes M1 GAS SPy1233 -223 4.4 TTGAAATGGTTTACAA
-32 4.2 ATGTAAGCACTGTCAA
Streptococcus sanguinis SK36 SSA_1033 -64 4.3 TGTAAATCGTTTTCAT
Streptococcus suis 05ZYH33 SSU05_1088 -89 4.7 CTAAAAACGTTTTCAA
-32 4 ATTGAAACGCTTACCT
Streptococcus thermophilus CNRZ1066 str0799 -45 4.3 TTGATAAGGCTTACAT
Streptococcus uberis 0140J SUB0955 -219 4.4 TTGAAATGGTTTACAA
Position: -77
Score: 4.3
Sequence: ATGAGAACGTATTCAT
Locus tag: M5005_Spy_0985
M5005_Spy_0985 -77 4.3 ATGAGAACGTATTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: phnA
Ortholog function: Zn-ribbon-containing protein involved in phosphonate metabolism
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1091 -77 4.5 ATGATAACGTATTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0885 -81 4.5 ATGATAACGTATTCAT
Streptococcus mitis B6 smi_0673 -111 3.9 TTGATATCGGTTTTTT
Streptococcus pneumoniae TIGR4 SP_1602 -111 3.9 TTGATATCGGTTTTTT
Streptococcus pyogenes M1 GAS SPy1277 -77 4.3 ATGAGAACGTATTCAT
Streptococcus uberis 0140J SUB0993 -88 4.2 CTGATAACGCATTCAT
Position: -163
Score: 4.3
Sequence: ATGAAAGCGATTACGA
Locus tag: M5005_Spy_1067
M5005_Spy_1067 -163 4.3 ATGAAAGCGATTACGA
Supported by regulated orthologs from reference regulons
Ortholog gene name: malX
Ortholog function: Maltose/maltodextrin ABC transporter, substrate-binding protein
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1305 -178 4.2 TTGTAAGCGATTACGA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1266 -190 4.3 CTGTAAGCGATTGCAT
Streptococcus mitis B6 smi_0133 -151 4 GATAAAGCGTTTACTT
-98 4.2 TTGCAACCGCTTTCTG
Streptococcus pneumoniae TIGR4 SP_2108 -98 4.4 TTGCAACCGTTTTCTA
Streptococcus pyogenes M1 GAS SPy1306 -163 4.3 ATGAAAGCGATTACGA
Streptococcus suis 05ZYH33 SSU05_2133 -110 4.6 ATAAAAACGCTTGCAA
-100 4.1 TTGCAAACGGATTCAA
Position: -34
Score: 5.1
Sequence: TAGAAAGCGTTTTCTA
Locus tag: M5005_Spy_1083
M5005_Spy_1083 -34 5.1 TAGAAAGCGTTTTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: celR
Ortholog function: Cellobiose utilization transcriptional regulator CelR, BglG family
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1400 -48 4.5 TTGTAAAGGTTTTCTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1282 -31 5.1 AAGAAAGCGTTTTCTA
Streptococcus gallolyticus UCN34 GALLO_1212 -56 4.9 ATGTAAGCGTTTTTAT
Streptococcus gordonii str. Challis substr. CH1 SGO_1579 -61 4.3 TTGATGGCGTTTTCAT
Streptococcus mutans UA159 SMU.1599 -55 4.8 TTGTAAGCGCTTTTTT
Streptococcus pneumoniae TIGR4 SP_0306 -90 4.5 TTGGAAACGCTTTATT
Streptococcus pyogenes M1 GAS SPy1325 -34 5.1 TAGAAAGCGTTTTCTA
Streptococcus suis 05ZYH33 SSU05_2076 -67 4.7 CAGAAATCGCTTTCAT
Streptococcus uberis 0140J SUB0530 -65 4.2 TTGAAAGCGTATACAC
Position: -168
Score: 5
Sequence: ATGTAAACGCTTTAAA
Locus tag: M5005_Spy_1086
M5005_Spy_1086 -168 5 ATGTAAACGCTTTAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pnuC
Ortholog function: Ribosyl nicotinamide transporter
Streptococcus pyogenes M1 GAS SPy1329 -168 5 ATGTAAACGCTTTAAA
Position: -53
Score: 4.3
Sequence: CTGTAAGCGCTTAATA
Locus tag: M5005_Spy_1093
M5005_Spy_1093 -53 4.3 CTGTAAGCGCTTAATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: SPy1339
Ortholog function: Dihydrolipoamide acyltransferase
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1320 -54 4.2 CTGAAAGCGCTTAATG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1291 -44 3.8 CTGTAAGCCCTTAATA
Streptococcus mutans UA159 SMU.799c -109 4.3 TAGGAAACGCTTCCAA
Streptococcus pyogenes M1 GAS SPy1339 -53 4.3 CTGTAAGCGCTTAATA
Position: -6
Score: 4
Sequence: TTTAAAATGCTTAAAA
Locus tag: M5005_Spy_1116
M5005_Spy_1116 -6 4 TTTAAAATGCTTAAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: udk
Ortholog function: Uridine kinase (EC 2.7.1.48) [C1]
Lactococcus lactis subsp. cremoris SK11 LACR_1825 -94 4.2 ATGTGAACGCTTAAAA
Lactococcus lactis subsp. lactis Il1403 L108994 -95 4.2 ATGTGAACGCTTAAAA
Streptococcus agalactiae 2603V/R SAG0826 -88 4.5 TTTAGAGCGTTTTCAA
Streptococcus gallolyticus UCN34 GALLO_0750 -79 4.1 AAGTAAGAGTTTTCAG
Position: -58
Score: 4.3
Sequence: TTGTAAGGGTTATCAT
Locus tag: M5005_Spy_1121
M5005_Spy_1121 -58 4.3 TTGTAAGGGTTATCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ptsH
Ortholog function: Phosphotransferase system, HPr-related protein
Streptococcus agalactiae 2603V/R SAG0821 -60 3.8 TTGTAAGGGTTACCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1421 -167 4 AAGAAAACGAATAAAA
-58 4.3 TTGTAAGGGTTATCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0764 -136 4.2 AAGAAAACTGTTTCAT
-58 4.3 TTGTAAGGGTTATCAT
Streptococcus gallolyticus UCN34 GALLO_0744 -200 4.4 ATGAAAACGCTCAAAA
-122 3.8 AAGAAAGCGCGCACAA
-58 4.3 TTGTAAGGGTTATCAT
Streptococcus gordonii str. Challis substr. CH1 SGO_1556 -90 4.4 TTGAAAAAGATTTCAA
-55 4.3 TTGTAAGGGTTATCAA
Streptococcus mitis B6 smi_1045 -196 4.2 TATAAATCGTTTTTAA
Streptococcus mutans UA159 SMU.674 -60 4.3 TTGTAAGGGTTATCAT
Streptococcus pyogenes M1 GAS SPy1373 -58 4.3 TTGTAAGGGTTATCAT
Streptococcus sanguinis SK36 SSA_0772 -90 4.4 TTGAAAAAGATTTCAA
Streptococcus suis 05ZYH33 SSU05_1201 -91 4.5 TTGAAAATGATTTCAA
Streptococcus thermophilus CNRZ1066 str1265 -56 4.3 TTGTAAGGGTTATCAT
Streptococcus uberis 0140J SUB1223 -137 3.8 AAGAAAACATTTCAAA
-60 3.9 TTGTAAGGGTTACCAT
Position: -53
Score: 4
Sequence: ATTAAAAGGTTTATAA
Locus tag: M5005_Spy_1154
M5005_Spy_1154 -53 4 ATTAAAAGGTTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: rheA
Ortholog function: Cold-shock DEAD-box protein A
Streptococcus agalactiae 2603V/R SAG0777 -142 4.2 ATGAAAGCGTGTTATT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1455 -146 4.2 ATGAAAACGTGTTATT
-53 4 ATTAAAAGGTTTATAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0646 -135 4.5 ATAAAAACACTTTCAT
-53 4 ATTAAAAGGTTTATAA
Streptococcus gallolyticus UCN34 GALLO_0655 -139 4.2 ATGAAAACGTGTTATT
-116 3.9 ATGAAACTGTTTCCTA
Streptococcus mutans UA159 SMU.611 -127 3.9 TTGAAAACGATCATTT
Streptococcus pyogenes M1 GAS SPy1415 -199 3.7 CAAAAAACGATATCTT
-53 4 ATTAAAAGGTTTATAA
Streptococcus suis 05ZYH33 SSU05_1574 -166 4.4 ATGAAAACGTATTATT
Streptococcus uberis 0140J SUB1250 -70 4.5 ATAAAAACCTTTTCAT
Position: -78
Score: 4.4
Sequence: TTGAAAGGGCTTGCAT
Locus tag: M5005_Spy_1161
M5005_Spy_1161 -78 4.4 TTGAAAGGGCTTGCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: fdhC
Ortholog function: Predicted formate transporter
Lactococcus lactis subsp. cremoris SK11 LACR_1054 -28 4.3 ATAAATACGCTTTCAG
Lactococcus lactis subsp. lactis Il1403 L195318 -29 4.3 ATAAATACGCTTTCAG
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1466 -51 4 ATGGAAGGGCTTGCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0639 -51 4.1 CTGAAAGTGCTTGCAT
Streptococcus pyogenes M1 GAS SPy1424 -78 4.4 TTGAAAGGGCTTGCAT
Streptococcus uberis 0140J SUB1260 -78 4 ATGGAAGGGCTTGCAT
Position: -90
Score: 4.3
Sequence: CTGAAAACATTTACAA
Locus tag: M5005_Spy_1255
M5005_Spy_1255 -90 4.3 CTGAAAACATTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: typA
Ortholog function: GTP-binding protein TypA/BipA
Lactococcus lactis subsp. cremoris SK11 LACR_2298 -167 3.8 TATTTAGCGATTTTAT
-71 4 TTGTAAACGTGTGCAT
Streptococcus agalactiae 2603V/R SAG0473 -96 4 ATGAAAACATTTACAC
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1513 -90 4.3 CTGAAAACATTTACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0589 -75 4.6 TTGAAAACATTTACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0669 -97 4 ATGAAAACATTTACAC
Streptococcus mutans UA159 SMU.546 -95 4.3 TTTAAAACATTTACAT
Streptococcus sanguinis SK36 SSA_0650 33 4 ATGAAAACATTTACAC
Streptococcus suis 05ZYH33 SSU05_0468 -89 4.3 CTGAAAACATTTACAA
Streptococcus thermophilus CNRZ1066 str0729 -89 4.3 TGAAAAACGTTTACAA
Streptococcus uberis 0140J SUB1296 -94 4.3 CTGAAAACATTTACAA
Position: -60
Score: 4.5
Sequence: TAGAAAGCGATTCCAT
Locus tag: M5005_Spy_1258
M5005_Spy_1258 -60 4.5 TAGAAAGCGATTCCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yvaA
Ortholog function: Bacterial conserved protein of unknown function (DUF910) family
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1516 -42 4.5 TAGAAAGCGATTCCAT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0586 -60 4.2 CAGAAAGCGATTGCAT
Streptococcus mutans UA159 SMU.541 -58 3.9 AGGCAAGCGCTTGCAA
Streptococcus pyogenes M1 GAS SPy1530 -60 4.5 TAGAAAGCGATTCCAT
Streptococcus thermophilus CNRZ1066 str0727 -58 4 CTATAAAGGTTTTCAA
Position: -182
Score: 4.2
Sequence: AAGTAAACGAATACAA
Position: -136
Score: 4.1
Sequence: ATGTAAGCGATTACTC
Locus tag: M5005_Spy_1275
M5005_Spy_1275 -182 4.2 AAGTAAACGAATACAA
-136 4.1 ATGTAAGCGATTACTC
Supported by regulated orthologs from reference regulons
Ortholog gene name: arcA
Ortholog function: Arginine deiminase (EC 3.5.3.6)
Streptococcus agalactiae 2603V/R SAG2163 -177 5 TAGAAATCGCTTTCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1548 -183 4.2 AAGTAAACGAATACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0568 -179 4.6 AAGAAAACGTATACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1593 -168 4.5 AAGAAAACGCTTCAAA
Streptococcus pyogenes M1 GAS SPy1547 -182 4.2 AAGTAAACGAATACAA
Streptococcus sanguinis SK36 SSA_0737 -169 4.9 AAGAAAACGCTTTAAA
Streptococcus suis 05ZYH33 SSU05_0624 -60 4.7 ATGTGAGCGTTTTCAA
Streptococcus uberis 0140J SUB1328 -189 4.5 AAGTAAACGTATACAT
Position: -88
Score: 4.3
Sequence: AGAAAAACGCTTTCTT
Locus tag: M5005_Spy_1291
M5005_Spy_1291 -88 4.3 AGAAAAACGCTTTCTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: cas3
Ortholog function: CRISPR-associated helicase Cas3
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0548 -88 4.7 ATGTATGCGTTTACAT
Streptococcus pyogenes M1 GAS SPy1567 -82 4.3 AGAAAAACGCTTTCTT
Position: -58
Score: 4.5
Sequence: ATGAAAGCGCTTGATA
Locus tag: M5005_Spy_1310
M5005_Spy_1310 -58 4.5 ATGAAAGCGCTTGATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: msmX
Ortholog function: Multiple sugar ABC transporter, membrane-spanning permease protein MsmF
Lactococcus lactis subsp. lactis Il1403 L129753 -62 4.3 AAGAAAGCGCAAACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1583 -77 4.7 ATGAAAAGGCTTTCTA
-10 4.4 ATGAAAGCGCTTGTTA
Streptococcus mitis B6 smi_1995 -69 4.6 ATGTAATCGTTATCAA
Streptococcus pneumoniae TIGR4 SP_0090 -38 4.6 ATGTAATCGTTATCAA
Streptococcus pyogenes M1 GAS SPy1595 -125 4.7 ATGAAAAGGCTTTCTA
-58 4.5 ATGAAAGCGCTTGATA
Position: -55
Score: 4.7
Sequence: TTGAAAAGGTTTACAA
Locus tag: M5005_Spy_1315
M5005_Spy_1315 -55 4.7 TTGAAAAGGTTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: araR
Ortholog function: Arabinoside utilization transcriptional regulator AraR, GntR family
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1589 -55 4.7 TTGAAAAGGTTTACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1508 -55 4.5 TAGAAAAGGTTTACAA
Streptococcus pyogenes M1 GAS SPy1602 -55 4.7 TTGAAAAGGTTTACAA
Position: -93
Score: 4.7
Sequence: TTGTAAACCTTTTCAA
Locus tag: M5005_Spy_1316
M5005_Spy_1316 -93 4.7 TTGTAAACCTTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: SPy1603
Ortholog function: Conserved hypothetical protein
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1590 -92 4.7 TTGTAAACCTTTTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1509 -94 4.5 TTGTAAACCTTTTCTA
Streptococcus pyogenes M1 GAS SPy1603 -66 4.7 TTGTAAACCTTTTCAA
Position: -35
Score: 4
Sequence: AAGTAAGCGCTTCAAG
Locus tag: M5005_Spy_1325
M5005_Spy_1325 -35 4 AAGTAAGCGCTTCAAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: raiA
Ortholog function: Ribosome-associated protein Y
Lactococcus lactis subsp. cremoris SK11 LACR_0667 -133 4.4 ATGAAAGCTGTTTCAT
Lactococcus lactis subsp. lactis Il1403 L32389 -133 4.4 ATGAAAGCTGTTTCAT
Streptococcus agalactiae 2603V/R SAG0338 -60 4.6 ATGAAAGCGGTTATAA
-36 4.7 TAGAAAGCGTTAACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1681 -64 4.5 ATGAAAGCGGTATAAT
-35 4.2 AAGAAAGCGCTTCAAG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1545 -36 4.9 AAGAAAGCGTTTTAAA
Streptococcus gallolyticus UCN34 GALLO_0504 -59 3.8 ATGAAAGCAGTATAAT
-34 4.8 AAGAAAGCGCTTTATA
Streptococcus gordonii str. Challis substr. CH1 SGO_0610 -63 4.7 ATGAAAGCGTTATAAT
Streptococcus mitis B6 smi_2056 -57 4.7 ATGAAAGCGTTATAAT
Streptococcus mutans UA159 SMU.500 -58 4.5 ATGAAAGCGATATAAT
Streptococcus pneumoniae TIGR4 SP_2206 -57 4.7 ATGAAAGCGTTATAAT
Streptococcus pyogenes M1 GAS SPy1613 -64 3.8 ATGAAAGCAGTATAAT
-35 4 AAGTAAGCGCTTCAAG
Streptococcus sanguinis SK36 SSA_1834 -60 4.7 ATGAAAGCGTTATAAT
Streptococcus suis 05ZYH33 SSU05_0439 -42 4.5 AAGAAAACGGTTGCAA
Streptococcus thermophilus CNRZ1066 str0370 -57 3.9 ATGAAAAGGATATAAT
-34 4.7 AAGAAAACGCTAACAA
Streptococcus uberis 0140J SUB1375 -59 4.4 ATGAAAACGGTATAAT
Position: -70
Score: 4.4
Sequence: TTTTTAGCGTTTTCTT
Locus tag: M5005_Spy_1344
M5005_Spy_1344 -70 4.4 TTTTTAGCGTTTTCTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: atoB
Ortholog function: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1700 -69 4.2 TTTTGAGCGTTTTCTT
-38 4.8 CAGAAAGCGCTTTCTA
Streptococcus pyogenes M1 GAS SPy1637 -70 4.4 TTTTTAGCGTTTTCTT
-39 3.9 TGGAAAGCGCTTTTCT
Streptococcus uberis 0140J SUB1394 -40 5.1 AAGAAAGCGCTTTCTA
Position: -46
Score: 4.6
Sequence: TAGAAAACGTTTAATT
Locus tag: M5005_Spy_1375
M5005_Spy_1375 -46 4.6 TAGAAAACGTTTAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: tkt
Ortholog function: Transketolase (EC 2.2.1.1)
Streptococcus pyogenes M1 GAS SPy_1676 -46 4.6 TAGAAAACGTTTAATT
Streptococcus uberis 0140J SUB1427 -103 3.9 TAAAAAAGGATTTCTA
-46 3.9 CGGAAAACGTTTAATT
Position: -48
Score: 3.9
Sequence: GGTAAAACGCTTTCAT
Locus tag: M5005_Spy_1378
M5005_Spy_1378 -48 3.9 GGTAAAACGCTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: hcaD
Ortholog function: NADH peroxidase (EC 1.11.1.1)
Streptococcus agalactiae 2603V/R SAG0276 -46 4.6 TTGTTACCGTTTTCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1739 -39 4.5 AGTAAAACGTTTTCAT
Streptococcus pyogenes M1 GAS SPy1681 -47 3.9 GGTAAAACGCTTTCAT
Streptococcus suis 05ZYH33 SSU05_0720 -66 4.4 TTGCAAGCCTTTTCAA
Position: -31
Score: 4.6
Sequence: AGGAAAACGCTTACTT
Locus tag: M5005_Spy_1381
M5005_Spy_1381 -31 4.6 AGGAAAACGCTTACTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: glpK
Ortholog function: Glycerol kinase (EC 2.7.1.30)
Streptococcus agalactiae 2603V/R SAG0273 -31 5 AAGAAAACGCTTACTT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1742 -32 4.9 AAGAAAACGCTTACTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1603 -59 4.6 TAGAAAGCGCTTGCTA
Streptococcus gordonii str. Challis substr. CH1 SGO_0632 -74 4.8 AAGAAAGCGTTTTATT
Streptococcus mitis B6 smi_2035 -76 4.8 AAGAAAGCGCTTTATT
Streptococcus pneumoniae TIGR4 SP_2186 -75 4.8 AAGAAAGCGCTTTATT
Streptococcus pyogenes M1 GAS SPy1684 -31 4.6 AGGAAAACGCTTACTT
Streptococcus sanguinis SK36 SSA_1826 -74 4.8 AAGAAAGCGTTTTATT
Streptococcus suis 05ZYH33 SSU05_0722 0 5 ATGGAAGCGTTTTCAA
Streptococcus uberis 0140J SUB1433 -30 4.3 AAGAAACCGCTTACCT
Position: -76
Score: 4.2
Sequence: TTGTAAACGGTTACCA
Locus tag: M5005_Spy_1401
M5005_Spy_1401 -76 4.2 TTGTAAACGGTTACCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: gatA
Ortholog function: PTS system, galactose-specific IIA component (EC 2.7.1.69)
Streptococcus gordonii str. Challis substr. CH1 SGO_1522 -54 4.4 AAGAAAGCGTTTTACT
Streptococcus pyogenes M1 GAS SPy1711 -76 4.2 TTGTAAACGGTTACCA
Streptococcus uberis 0140J SUB1460 -75 4.3 TTGCAAACGATTACTA
Position: -176
Score: 4.2
Sequence: TGGTAACCGTTTACAA
Locus tag: M5005_Spy_1402
M5005_Spy_1402 -176 4.2 TGGTAACCGTTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: lacR2
Ortholog function: Lactose phosphotransferase system transcriptional regulator LacR, DeoR family
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1767 -173 3.9 CGGTAACCGTTTACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0452 -159 4 TGTTAATCGTTTACAA
Streptococcus pyogenes M1 GAS SPy1712 -176 4.2 TGGTAACCGTTTACAA
Streptococcus uberis 0140J SUB1461 -156 4.3 TAGTAATCGTTTGCAA
Position: -131
Score: 4.4
Sequence: GTGAAAACGTTTTAAA
Locus tag: M5005_Spy_1479
M5005_Spy_1479 -131 4.4 GTGAAAACGTTTTAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: manL
Ortholog function: PTS system, mannose-specific IIAB components
Lactococcus lactis subsp. cremoris SK11 LACR_1863 -87 4.3 ATGAAAACATTTGCAA
Lactococcus lactis subsp. lactis Il1403 L1762179 -87 4.3 ATGAAAACATTTGCAA
Streptococcus agalactiae 2603V/R SAG0361 -130 4.7 CTGAAAACGTTTTAAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1806 -131 4.4 GTGAAAACGTTTTAAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0423 -131 4.4 GTGAAAACGTTTTAAA
Streptococcus gallolyticus UCN34 GALLO_0350 -128 4.5 TTGAAAACGTTTTACA
Streptococcus gordonii str. Challis substr. CH1 SGO_1679 -80 4.6 CTGAAAACGTTTTATA
Streptococcus mitis B6 smi_0274 -124 4.2 ATTTAAATGTTTTCTT
-77 4.6 ATGAAAACGGTTTATA
Streptococcus mutans UA159 SMU.1877 -105 4.4 ATGTAAACGTTTTACA
Streptococcus pneumoniae TIGR4 SP_0284 -68 4.6 ATGAAAACGGTTTATA
Streptococcus pyogenes M1 GAS SPy1738 -131 4.4 GTGAAAACGTTTTAAA
Streptococcus sanguinis SK36 SSA_1918 -71 4.9 ATGAAAACGTTTTATA
Streptococcus suis 05ZYH33 SSU05_1778 -91 4.2 CTGTAATCGTTTTATA
-59 4.4 ATGAAAGCCCATTCAA
Streptococcus thermophilus CNRZ1066 str0333 -139 4.5 ATGATAACGCTTTATA
Streptococcus uberis 0140J SUB1482 -130 5 TTGAAAACGTTTTAAA
Position: -36
Score: 4
Sequence: ATGAAAGCGCAAATAA
Locus tag: M5005_Spy_1512
M5005_Spy_1512 -36 4 ATGAAAGCGCAAATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: codY
Ortholog function: Amino acid metabolism global transcriptional regulator CodY, CodY family
Streptococcus gallolyticus UCN34 GALLO_1876 -112 4.6 AAGAATGCGTTTACAA
Streptococcus mutans UA159 SMU.1824c -112 4.6 ATAAAAGGGCTTTCAT
Streptococcus pneumoniae TIGR4 SP_1584 -28 4.3 ATGATAGCGATTAAAT
Streptococcus pyogenes M1 GAS SPy1777 -36 4 ATGAAAGCGCAAATAA
Position: -65
Score: 4.2
Sequence: AATAAAACGTTTACCA
Position: 0
Score: 4.2
Sequence: ATGAAAACGTTAAGAA
Locus tag: M5005_Spy_1598
M5005_Spy_1598 -65 4.2 AATAAAACGTTTACCA
0 4.2 ATGAAAACGTTAAGAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: SPy1879
Ortholog function: Predicted membrane protein
Streptococcus agalactiae 2603V/R SAG1765 -65 4.8 AATAAAACGTTTACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1933 -110 3.9 AGGAAAACGTCTTCTT
Streptococcus gallolyticus UCN34 GALLO_1994 -157 4.1 AAGAAAACATTTTATT
-86 4.2 TGGTAAACGCATTCAT
Streptococcus pyogenes M1 GAS SPy1879 -65 4.2 AATAAAACGTTTACCA
Position: -107
Score: 4.2
Sequence: TGGAAAACGCTTTAAG
Locus tag: M5005_Spy_1607
M5005_Spy_1607 -107 4.2 TGGAAAACGCTTTAAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: fbaA
Ortholog function: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)
Lactococcus lactis subsp. cremoris SK11 LACR_2168 -100 4.4 AATAAAGCGGTTACTT
Lactococcus lactis subsp. lactis Il1403 L0009 -100 4.4 AATAAAGCGGTTACTT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0336 -107 4 GAGAAAACGCTTTAAG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1717 -19 4 GAGAAAACGCTTTAAG
Streptococcus mitis B6 smi_0695 -137 4.6 TAGAAAGGGTTTACAT
Streptococcus pyogenes M1 GAS SPy1889 -107 4.2 TGGAAAACGCTTTAAG
Streptococcus thermophilus CNRZ1066 str1899 -106 4.6 ATCAAAACGCTTACAA
-44 4.2 ATGTAAACGGGTTCAA
Position: -65
Score: 4.7
Sequence: TTAAAAACGCTTTAAA
Locus tag: M5005_Spy_1612
M5005_Spy_1612 -65 4.7 TTAAAAACGCTTTAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ropA
Ortholog function: Cell division trigger factor (EC 5.2.1.8)
Streptococcus agalactiae 2603V/R SAG0105 -65 4.2 TGTAAAACGTTTTAAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0327 22 4.7 TTAAAAACGCTTTAAA
Streptococcus mutans UA159 SMU.91 -161 4.6 ATGAAAAGGATTTCAT
Streptococcus pneumoniae TIGR4 SP_0400 -53 3.9 TAGAAAATGTTATAAT
Streptococcus pyogenes M1 GAS SPy1896 -65 4.7 TTAAAAACGCTTTAAA
Streptococcus suis 05ZYH33 SSU05_0328 -65 4 TTGAAATCCTTGTCAA
Position: -145
Score: 4.8
Sequence: TTGTAAACGTTTTATT
Position: -131
Score: 4.3
Sequence: TTTAAAACATTTTCTA
Locus tag: M5005_Spy_1639
M5005_Spy_1639 -145 4.8 TTGTAAACGTTTTATT
-131 4.3 TTTAAAACATTTTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: lacR2
Ortholog function: Lactose phosphotransferase system transcriptional regulator LacR, DeoR family
Streptococcus agalactiae 2603V/R SAG1936 -199 4 AGTTAAGCGGTTACAT
Streptococcus gallolyticus UCN34 GALLO_0176 -269 4.5 TTAAAAACGTTTTTTT
Streptococcus pyogenes M1 GAS SPy1924 -145 4.8 TTGTAAACGTTTTATT
-131 4.3 TTTAAAACATTTTCTA
Position: -155
Score: 4.4
Sequence: AAGAAAACGCTTTACA
Position: -101
Score: 4.3
Sequence: ATGCAAGCGATTGCAT
Locus tag: M5005_Spy_1693
M5005_Spy_1693 -155 4.4 AAGAAAACGCTTTACA
-101 4.3 ATGCAAGCGATTGCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ptsG
Ortholog function: PTS system glucose-specific EIICBA component (EC 2.7.1.69)
Streptococcus agalactiae 2603V/R SAG1959 -92 4.4 AAGTAAGGGTTTACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0222 -154 4.4 AAGAAAACGCTTTACA
-49 4.1 ATGATAGCGATTACCT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1783 -158 4.4 AAGAAAACGCTTTACA
Streptococcus gordonii str. Challis substr. CH1 SGO_0505 -96 4 ATGAAAACCCTTTACA
-47 4.7 ATGCAAACGATTTCAT
Streptococcus mitis B6 smi_1404 -103 4.4 ATAAAAGCCTTTACAA
Streptococcus mutans UA159 SMU.2047 -43 4.5 ATGCAAACGTTTGCAT
Streptococcus pneumoniae TIGR4 SP_0758 -102 4.4 ATAAAAGCCTTTACAA
Streptococcus pyogenes M1 GAS SPy1986 -155 4.4 AAGAAAACGCTTTACA
-101 4.3 ATGCAAGCGATTGCAT
Streptococcus sanguinis SK36 SSA_1809 -193 4 ATGCAATCGTTTTCGT
-103 4.4 ATAAAAGCCTTTACAA
-54 4.1 ATGCAAACGATTTCAC
Streptococcus thermophilus CNRZ1066 str0189 -72 4.4 AAGAAAACGCTTTACA
-21 3.9 ATGCAAACGCTCGCAT
Streptococcus thermophilus CNRZ1066 str0190 -72 4.4 AAGAAAACGCTTTACA
-21 3.9 ATGCAAACGCTCGCAT
Streptococcus thermophilus CNRZ1066 str0191 -72 4.4 AAGAAAACGCTTTACA
-21 3.9 ATGCAAACGCTCGCAT
Streptococcus uberis 0140J SUB0236 -120 4.3 TAGAAAACGCTTTACA
Position: -30
Score: 4.1
Sequence: TAGCAACCGCTTTTAT
Locus tag: M5005_Spy_1697
M5005_Spy_1697 -30 4.1 TAGCAACCGCTTTTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pabB
Ortholog function: Para-aminobenzoate synthase component I (EC 4.1.3.-); Anthranilate/para-aminobenzoate synthases component I/ Chorismate binding enzyme, putative
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0217 -24 4.1 TAGCAACCGCTTTTAT
Streptococcus gordonii str. Challis substr. CH1 SGO_0307 -98 4.8 ATAAAACCGTTTTCAT
-48 4 AAGAAAACGATTATTG
Streptococcus pyogenes M1 GAS SPy1990 -30 4.1 TAGCAACCGCTTTTAT
Streptococcus sanguinis SK36 SSA_0413 -147 4 ATTTATTCGATTTCAT
-44 4.3 ATAAATCCGTTTTCAT
Position: -90
Score: 4.9
Sequence: ATGTAAACGATTACAA
Locus tag: M5005_Spy_1746
M5005_Spy_1746 -90 4.9 ATGTAAACGATTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: celX
Ortholog function: Cellobiose-specific PTS system, IIA component (EC 2.7.1.69)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0172 -79 4.8 AAGAAAACGATTACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1811 -85 4.9 ATGTAAACGATTACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1791 -64 5.1 ATAAAAGCGCTTTCAT
-41 3.8 AAATAAACGTTGTTAA
Streptococcus pyogenes M1 GAS SPy2052 -90 4.9 ATGTAAACGATTACAA
Streptococcus sanguinis SK36 SSA_0282 -66 4.1 AATAAATCACTTTCAA
Position: -235
Score: 5
Sequence: TTGTAAACGCTTTAAT
Locus tag: M5005_Spy_1768
M5005_Spy_1768 -235 5 TTGTAAACGCTTTAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ahpC
Ortholog function: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
Streptococcus agalactiae 2603V/R SAG1833 -77 4.9 ATGTAAACGTTTTTAT
Streptococcus uberis 0140J SUB1752 -80 4.3 AATCAAGCGCTTTCTT
Position: -111
Score: 4.3
Sequence: TTGCAATCGATTACAA
Locus tag: M5005_Spy_1784
M5005_Spy_1784 -111 4.3 TTGCAATCGATTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: treP
Ortholog function: Trehalose-specific PTS system, IIABC components (EC 2.7.1.69)
Streptococcus agalactiae 2603V/R SAG0192 -93 4.9 ATGTAATCGTTTACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2069 -111 4.3 TTGCAATCGATTACAA
Streptococcus gallolyticus UCN34 GALLO_2175 -82 4.4 TGGAAAACGATTACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1653 -89 4.1 TTGGTATCGTTTACAA
Streptococcus mutans UA159 SMU.2038 -77 4.8 TTGTAATCGTTTACAA
Streptococcus pneumoniae TIGR4 SP_1884 -63 4.1 TTGGTATCGTTTACAA
Streptococcus pyogenes M1 GAS SPy2097 -111 4.3 TTGCAATCGATTACAA
Streptococcus sanguinis SK36 SSA_1752 -30 4.3 TTGGAATCGATTACAA
Streptococcus suis 05ZYH33 SSU05_0231 -128 4.2 TTGAAATCGGATACAA
Streptococcus uberis 0140J SUB1763 -118 4.3 TTGGAATCGATTACAA
Position: -115
Score: 4.3
Sequence: TTGTAATCGATTGCAA
Locus tag: M5005_Spy_1785
M5005_Spy_1785 -115 4.3 TTGTAATCGATTGCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: treR
Ortholog function: Trehalose utilization transcriptional regulator TreR, GntR family
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2070 -115 4.3 TTGTAATCGATTGCAA
Streptococcus gallolyticus UCN34 GALLO_2176 -129 4.4 TTGTAATCGTTTTCCA
Streptococcus gordonii str. Challis substr. CH1 SGO_1654 -106 4.1 TTGTAAACGATACCAA
Streptococcus mutans UA159 SMU.2040 -112 4.8 TTGTAAACGATTACAA
Streptococcus pneumoniae TIGR4 SP_1885 -137 4.1 TTGTAAACGATACCAA
Streptococcus pyogenes M1 GAS SPy2099 -115 4.3 TTGTAATCGATTGCAA
Streptococcus sanguinis SK36 SSA_1753 -104 4.3 TTGTAATCGATTCCAA
Streptococcus suis 05ZYH33 SSU05_0232 -118 4.2 TTGTATCCGATTTCAA
Streptococcus uberis 0140J SUB1764 -117 4.3 TTGTAATCGATTCCAA
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