Propagation of CmbR regulog to Streptococcus sanguinis SK36

Reference regulog properties
Source regulog:	CmbR - Streptococcaceae
Regulator type:	Transcription factor
Regulator family:	LysR
Regulation mode:	repressor (activator)
Biological process:	Cysteine metabolism
Effector:	O-acetyl-L-serine
Phylum:	Firmicutes
Propagated regulon:
Target genome	Streptococcus sanguinis SK36
Orthologous TF(s)	SSA_1068, SSA_1245
Regulated genes	7

Built upon 104 sites [see more]

Predicted regulatory interactions in *Streptococcus sanguinis SK36*
	Locus tag	Position	Score	Sequence
Position: -182 Score: 4.3 Sequence: GTCATAATTTCTACCTATAGC Position: -99 Score: 4.1 Sequence: GTTATAGTTTTAGACTATATC Locus tag: SSA_0416
	SSA_0416	-182	4.3	GTCATAATTTCTACCTATAGC
		-99	4.1	GTTATAGTTTTAGACTATATC
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Lactococcus lactis subsp. cremoris SK11	LACR_1368	-39	4.7	TTGATAAGATAGACCTATTAA
Lactococcus lactis subsp. lactis Il1403	L0100	-76	4.1	ATCATATTAAAAATGTATTAT
		-39	4.7	TTGATAAGATAGACCTATTAA
Streptococcus agalactiae 2603V/R	SAG2049	-109	4.1	GCTAAAAATATAAAATATTAA
Streptococcus gallolyticus UCN34	GALLO_1316	-221	4.2	ATAATAAATTTTATTAATCTA
		-172	4.6	GTTATAGTTAAAAACTATAAT
Streptococcus gordonii str. Challis substr. CH1	SGO_0310	-182	4.2	GTTATAGTTTTTGATTATACC
Streptococcus mutans UA159	SMU.873	-188	4.6	GTTATAGATGAAAACTATAAC
Streptococcus pneumoniae TIGR4	SP_0585	-218	4.9	CTTATAAGAATTACTAATAAC
Streptococcus sanguinis SK36	SSA_0416	-182	4.3	GTCATAATTTCTACCTATAGC
Streptococcus suis 05ZYH33	SSU05_1774	-237	4.3	TTCATAGATAAAATCTATACC
Streptococcus thermophilus CNRZ1066	str0785	-119	4.2	GCTATACAAATATCTAATTAA

Position: -100 Score: 4.8 Sequence: CTGATAAAGAAAAGCTATCAC Locus tag: SSA_0588
	SSA_0588	-100	4.8	CTGATAAAGAAAAGCTATCAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: gshT
Ortholog function: Predicted glutathione ABC transporter, substrate-binding protein
Streptococcus gordonii str. Challis substr. CH1	SGO_0457	-85	4.7	GCAATAAATAAAATTTATACC
Streptococcus sanguinis SK36	SSA_0588	-100	4.8	CTGATAAAGAAAAGCTATCAC

Position: -228 Score: 5.3 Sequence: GTGATAAGAAAAATATATTAG Locus tag: SSA_1868
	SSA_1868	-228	5.3	GTGATAAGAAAAATATATTAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyB
Ortholog function: Cystine ABC transporter, permease protein
Lactococcus lactis subsp. cremoris SK11	LACR_1010	-77	5.1	GCTATAAGTTTTTTTTATGGC
Lactococcus lactis subsp. lactis Il1403	L163056	-77	5.1	GCTATAAGTTTTTTTTATGGC
Streptococcus agalactiae 2603V/R	SAG0291	-96	5.5	TTGATATAAAATCTTTATCAC
		-75	4.7	CTGATAAGGAAATACTATTAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1719	-99	5.3	GTGATAAGTTTTGCTTATTGC
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1580	-106	5	GCGATAGGCTTTTCTTATCGT
Streptococcus gallolyticus UCN34	GALLO_0415	-100	5.2	CTGATAGTTTTTTCTTATCAA
Streptococcus gordonii str. Challis substr. CH1	SGO_0578	-170	4.7	GTCATAAAATTTGCTTATACC
		-148	4.3	TTGATAAATAATTTATACTGT
Streptococcus mitis B6	smi_1382	-164	4.7	GAGATAGTTTTTACTTATCTC
		-142	5	TTGATAGATAAAATATATAGC
Streptococcus mutans UA159	SMU.460	-102	5.8	GTGATAGAAAAATATTATCAC
		-80	5	GTGATAGGAAAAAACTATTAT
Streptococcus pneumoniae TIGR4	SP_1461	-164	4.3	GAAATAGTTTTTATCTATCTC
		-142	5.2	TTGATAGATAAAATATATAAC
Streptococcus sanguinis SK36	SSA_1868	-250	5.4	GTGATATACTTTTCTTATCGC
		-228	5.3	GTGATAAGAAAAATATATTAG
Streptococcus thermophilus CNRZ1066	str1653	-217	5.8	GTGATATGATTTACTTATCAC
Streptococcus uberis 0140J	SUB1415	-80	4.8	GTGATAGGCTTTAACTATTGC

Position: -194 Score: 5.3 Sequence: TTGATAAAAATTACCTATCTC Position: -59 Score: 5.1 Sequence: TTGATAAATATTTTTAATCAG Locus tag: SSA_2105
	SSA_2105	-194	5.3	TTGATAAAAATTACCTATCTC
		-59	5.1	TTGATAAATATTTTTAATCAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyD
Ortholog function: Predicted uroporphyrinogen-III decarboxylase
Streptococcus gallolyticus UCN34	GALLO_1275	-104	4.9	GCTATAAGCAAATCTTATGGC
Streptococcus mutans UA159	SMU.932	-168	5	GTGATAACTTTTTCTTATGGC
		-103	5.3	GTCATAAATAAAATTTATAGC
Streptococcus sanguinis SK36	SSA_2105	-194	5.3	TTGATAAAAATTACCTATCTC
		-59	5.1	TTGATAAATATTTTTAATCAG
Streptococcus sanguinis SK36	SSA_2102	-194	5.3	TTGATAAAAATTACCTATCTC
		-59	5.1	TTGATAAATATTTTTAATCAG

Position: -100 Score: 5.8 Sequence: CTGATAAAAAATTTTTATAAC Locus tag: SSA_2164
	SSA_2164	-100	5.8	CTGATAAAAAATTTTTATAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: yvdE
Ortholog function: Predicted glutamine amidotransferase, class I
Streptococcus gallolyticus UCN34	GALLO_1848	-98	5.2	GTGATAAAAAAAATCTATTGG
		-61	5	AGGATAGAATAATCTTATCAC
Streptococcus gordonii str. Challis substr. CH1	SGO_0167	-97	5.5	TTGATAAAAAATTTTTATAAG
Streptococcus pneumoniae TIGR4	SP_2072	-64	5.2	TCCATAAAAAATGTTTATCAC
Streptococcus sanguinis SK36	SSA_2164	-100	5.8	CTGATAAAAAATTTTTATAAC
Streptococcus suis 05ZYH33	SSU05_1773	-95	5.3	CTGATAGTTATTTTTTATCAA

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of CmbR regulog to Streptococcus sanguinis SK36

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --