Propagation of CmbR regulog to Streptococcus pneumoniae CDC0288-04
| Source regulog: | CmbR - Streptococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | LysR |
| Regulation mode: | repressor (activator) |
| Biological process: | Cysteine metabolism |
| Effector: | O-acetyl-L-serine |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Streptococcus pneumoniae CDC0288-04 |
| Orthologous TF(s) | SP28804_0586, SpneCD_010100002715 |
| Regulated genes | 8 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -100
Score: 4.9 Sequence: ATGATTAAGTTTTTCTATCAC
Locus tag: SpneCD_010100000035
|
||||
| SpneCD_010100000035 | -100 | 4.9 | ATGATTAAGTTTTTCTATCAC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: gshT | ||||
| Ortholog function: Predicted glutathione ABC transporter, substrate-binding protein | ||||
| Streptococcus gallolyticus UCN34 | GALLO_1847 | -98 | 5.2 | GTGATAAAAAAAATCTATTGG |
| -61 | 5 | AGGATAGAATAATCTTATCAC | ||
| Streptococcus mitis B6 | smi_1579 | -101 | 5.1 | ATGATTAAGTTTTTTTATCAC |
| Streptococcus pneumoniae TIGR4 | SP_0620 | -100 | 4.9 | ATGATTAAGTTTTTCTATCAC |
| Streptococcus thermophilus CNRZ1066 | str0908 | -101 | 5.2 | TTGATAGATATTGTTTATCAG |
|
Position: -250
Score: 4.5 Sequence: GTTATAGTCTTTTCTAATAAC
Position: -217
Score: 4.9 Sequence: CTTATAAGAATTACTAATAAC
Locus tag: SpneCD_010100000200
|
||||
| SpneCD_010100000200 | -250 | 4.5 | GTTATAGTCTTTTCTAATAAC | |
| -217 | 4.9 | CTTATAAGAATTACTAATAAC | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metE | ||||
| Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1368 | -39 | 4.7 | TTGATAAGATAGACCTATTAA |
| Lactococcus lactis subsp. lactis Il1403 | L0100 | -76 | 4.1 | ATCATATTAAAAATGTATTAT |
| -39 | 4.7 | TTGATAAGATAGACCTATTAA | ||
| Streptococcus agalactiae 2603V/R | SAG2049 | -109 | 4.1 | GCTAAAAATATAAAATATTAA |
| Streptococcus gallolyticus UCN34 | GALLO_1316 | -221 | 4.2 | ATAATAAATTTTATTAATCTA |
| -172 | 4.6 | GTTATAGTTAAAAACTATAAT | ||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0310 | -182 | 4.2 | GTTATAGTTTTTGATTATACC |
| Streptococcus mutans UA159 | SMU.873 | -188 | 4.6 | GTTATAGATGAAAACTATAAC |
| Streptococcus pneumoniae TIGR4 | SP_0585 | -218 | 4.9 | CTTATAAGAATTACTAATAAC |
| Streptococcus sanguinis SK36 | SSA_0416 | -182 | 4.3 | GTCATAATTTCTACCTATAGC |
| Streptococcus suis 05ZYH33 | SSU05_1774 | -237 | 4.3 | TTCATAGATAAAATCTATACC |
| Streptococcus thermophilus CNRZ1066 | str0785 | -119 | 4.2 | GCTATACAAATATCTAATTAA |
|
Position: -145
Score: 4.6 Sequence: GATATAAAAATAGACTATAAC
Locus tag: SpneCD_010100005335
|
||||
| SpneCD_010100005335 | -145 | 4.6 | GATATAAAAATAGACTATAAC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metA | ||||
| Ortholog function: Homoserine O-succinyltransferase (EC 2.3.1.46) | ||||
| Lactococcus lactis subsp. lactis Il1403 | L0101 | -132 | 4.3 | GCCATAGGCAAGTTTTATTAT |
| Streptococcus gallolyticus UCN34 | GALLO_0824 | -107 | 4.3 | ATTATAGCTAAAAACTATAAC |
| Streptococcus pneumoniae TIGR4 | SP_1576 | -145 | 4.6 | GATATAAAAATAGACTATAAC |
| Streptococcus suis 05ZYH33 | SSU05_1306 | -46 | 4.7 | GTTATAGCCAAAACTTATAAC |
|
Position: -103
Score: 5.2 Sequence: TCCATAAAAAATGTTTATCAC
Locus tag: SpneCD_010100005677
|
||||
| SpneCD_010100005677 | -103 | 5.2 | TCCATAAAAAATGTTTATCAC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: yvdE | ||||
| Ortholog function: Predicted glutamine amidotransferase, class I | ||||
| Streptococcus gallolyticus UCN34 | GALLO_1848 | -98 | 5.2 | GTGATAAAAAAAATCTATTGG |
| -61 | 5 | AGGATAGAATAATCTTATCAC | ||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0167 | -97 | 5.5 | TTGATAAAAAATTTTTATAAG |
| Streptococcus pneumoniae TIGR4 | SP_2072 | -64 | 5.2 | TCCATAAAAAATGTTTATCAC |
| Streptococcus sanguinis SK36 | SSA_2164 | -100 | 5.8 | CTGATAAAAAATTTTTATAAC |
| Streptococcus suis 05ZYH33 | SSU05_1773 | -95 | 5.3 | CTGATAGTTATTTTTTATCAA |
|
Position: -98
Score: 4.6 Sequence: GATATATAGAAATCCTATCGC
Locus tag: SpneCD_010100006442
|
||||
| SpneCD_010100006442 | -98 | 4.6 | GATATATAGAAATCCTATCGC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysK | ||||
| Ortholog function: Cysteine synthase (EC 2.5.1.47) | ||||
| Lactococcus lactis subsp. lactis Il1403 | L0089 | -79 | 5.3 | GCTATAAAAAAATCTTATAGC |
| Lactococcus lactis subsp. lactis Il1403 | L0088 | -87 | 4.5 | ATCATAAATTTTTTTTAGAGC |
| Streptococcus mitis B6 | smi_2060 | -98 | 5.3 | GATATAAAAAAATCCTATCAC |
| Streptococcus thermophilus CNRZ1066 | str0366 | -16 | 5.2 | ATGATAAAATTTTTTTATGGA |
| Streptococcus uberis 0140J | SUB1379 | -104 | 5.1 | ATGATAAGCCTTTCCTATCAC |
|
Position: -177
Score: 4.6 Sequence: ATTATAAAAATATCTTAACTC
Position: -102
Score: 4.8 Sequence: ATGGTAAAAAATCCTTATAAC
Position: -80
Score: 4.4 Sequence: GCAATAAAAAATAGATATTAT
Locus tag: SpneCD_010100009120
|
||||
| SpneCD_010100009120 | -177 | 4.6 | ATTATAAAAATATCTTAACTC | |
| -102 | 4.8 | ATGGTAAAAAATCCTTATAAC | ||
| -80 | 4.4 | GCAATAAAAAATAGATATTAT | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: str1582 | ||||
| Ortholog function: Predicted polar amino acid ABC transporter, permease protein 1 | ||||
| Streptococcus gallolyticus UCN34 | GALLO_1237 | -96 | 5.3 | GCTATAAAAATTATTTATGGC |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0985 | -139 | 5.2 | CTTATAAATTTTTTCTATCAG |
| -117 | 4.9 | CCGATAAAATATACATATTAT | ||
| Streptococcus mitis B6 | smi_1436 | -102 | 5.5 | ATGATAAAAAATCCTTATAAC |
| -80 | 4.4 | GCAATAAAAAATAGATATTAT | ||
| Streptococcus pneumoniae TIGR4 | SP_0711 | -140 | 4.4 | GCAATAAAAAATAGATATTAT |
| Streptococcus thermophilus CNRZ1066 | str1582 | -237 | 4.8 | GTTATATCTTTTCTTTATCAC |
| -215 | 5.2 | TTGATAAAAAATACATATTAT | ||
|
Position: -142
Score: 5.2 Sequence: TTGATAGATAAAATATATAAC
Locus tag: SpneCD_010100010773
|
||||
| SpneCD_010100010773 | -142 | 5.2 | TTGATAGATAAAATATATAAC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: tcyB | ||||
| Ortholog function: Cystine ABC transporter, permease protein | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1010 | -77 | 5.1 | GCTATAAGTTTTTTTTATGGC |
| Lactococcus lactis subsp. lactis Il1403 | L163056 | -77 | 5.1 | GCTATAAGTTTTTTTTATGGC |
| Streptococcus agalactiae 2603V/R | SAG0291 | -96 | 5.5 | TTGATATAAAATCTTTATCAC |
| -75 | 4.7 | CTGATAAGGAAATACTATTAT | ||
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1719 | -99 | 5.3 | GTGATAAGTTTTGCTTATTGC |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1580 | -106 | 5 | GCGATAGGCTTTTCTTATCGT |
| Streptococcus gallolyticus UCN34 | GALLO_0415 | -100 | 5.2 | CTGATAGTTTTTTCTTATCAA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0578 | -170 | 4.7 | GTCATAAAATTTGCTTATACC |
| -148 | 4.3 | TTGATAAATAATTTATACTGT | ||
| Streptococcus mitis B6 | smi_1382 | -164 | 4.7 | GAGATAGTTTTTACTTATCTC |
| -142 | 5 | TTGATAGATAAAATATATAGC | ||
| Streptococcus mutans UA159 | SMU.460 | -102 | 5.8 | GTGATAGAAAAATATTATCAC |
| -80 | 5 | GTGATAGGAAAAAACTATTAT | ||
| Streptococcus pneumoniae TIGR4 | SP_1461 | -164 | 4.3 | GAAATAGTTTTTATCTATCTC |
| -142 | 5.2 | TTGATAGATAAAATATATAAC | ||
| Streptococcus sanguinis SK36 | SSA_1868 | -250 | 5.4 | GTGATATACTTTTCTTATCGC |
| -228 | 5.3 | GTGATAAGAAAAATATATTAG | ||
| Streptococcus thermophilus CNRZ1066 | str1653 | -217 | 5.8 | GTGATATGATTTACTTATCAC |
| Streptococcus uberis 0140J | SUB1415 | -80 | 4.8 | GTGATAGGCTTTAACTATTGC |