Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of MtaR regulog to Streptococcus pneumoniae SP14-BS69

Reference regulog properties
Source regulog: MtaR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LysR
Regulation mode: repressor
Biological process: Methionine metabolism
Effector: Homocysteine
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pneumoniae SP14-BS69
Orthologous TF(s) CGSSp14BS69_01979
Regulated genes 5
Built upon 72 sites [see more]
Predicted regulatory interactions in Streptococcus pneumoniae SP14-BS69
Locus tag Position Score Sequence
Position: -99
Score: 6.5
Sequence: TATAGTTTTAAACTATA
Locus tag: CGSSp14BS69_08425
CGSSp14BS69_08425 -99 6.5 TATAGTTTTAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metQ
Ortholog function: Methionine ABC transporter, substrate-binding protein
Streptococcus mitis B6 smi_1944 -99 6.2 TATAGCTTTAAACTATA
Streptococcus pneumoniae TIGR4 SP_0149 -99 6.5 TATAGTTTTAAACTATA
Position: -156
Score: 6.4
Sequence: TATAGTTTCAAACTATA
Locus tag: CGSSp14BS69_04233
CGSSp14BS69_04233 -156 6.4 TATAGTTTCAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: fhs
Ortholog function: Formate--tetrahydrofolate ligase (EC 6.3.4.3)
Streptococcus gordonii str. Challis substr. CH1 SGO_1210 -42 4.8 TTTTGTTATAATCTATA
Streptococcus mitis B6 smi_1192 -157 6.4 TATAGTTTCAAACTATA
Streptococcus pneumoniae TIGR4 SP_1229 -156 6.4 TATAGTTTCAAACTATA
Streptococcus uberis 0140J SUB0942 -129 4.6 TAAAGATATACACTATA
Position: -93
Score: 6.2
Sequence: TATAGTTTGAAACTATA
Locus tag: CGSSp14BS69_02594
CGSSp14BS69_02594 -93 6.2 TATAGTTTGAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metB
Ortholog function: Cystathionine gamma-synthase (EC 2.5.1.48)
Streptococcus gallolyticus UCN34 GALLO_1768 -140 5.2 TATAGTTTTTACTTATA
Streptococcus gordonii str. Challis substr. CH1 SGO_1636 -101 6.1 TATAGTTTCAGACTATA
Streptococcus mitis B6 smi_1508 -93 6.2 TATAGTTTGAAACTATA
Streptococcus pneumoniae TIGR4 SP_1525 -93 6.2 TATAGTTTGAAACTATA
Streptococcus sanguinis SK36 SSA_1737 -44 6.4 TATAGTTTCAAACTATA
Streptococcus thermophilus CNRZ1066 str0352 -130 5.9 TATAGTAATAAACTATA
Position: -91
Score: 5.2
Sequence: TATAAGTTAAAACTATA
Locus tag: CGSSp14BS69_13605
CGSSp14BS69_13605 -91 5.2 TATAAGTTAAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: COG1912
Ortholog function: Conserved hypothetical protein
Streptococcus gordonii str. Challis substr. CH1 SGO_0468 -30 4.5 TAAAGTTCAGGACTATA
Streptococcus mitis B6 smi_1812 -91 4.6 TATAAGGTAAAACTATA
Streptococcus mutans UA159 SMU.1936c -110 5.4 TATAGGTAATAACTATA
Streptococcus pneumoniae TIGR4 SP_0481 -64 4.6 TATAAGGTAAAACTATA
Streptococcus thermophilus CNRZ1066 str0304 -100 4.5 CATAGCCAAAGGCTATA
Streptococcus uberis 0140J SUB0314 -106 6.3 TATAGTTTTAGACTATA
Position: -98
Score: 6.2
Sequence: TATAGTTTGAAACTATA
Locus tag: CGSSp14BS69_07248
CGSSp14BS69_07248 -98 6.2 TATAGTTTGAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: folD
Ortholog function: Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
Streptococcus mitis B6 smi_0869 -35 6.2 TATAGTTTGAAACTATA
Streptococcus mutans UA159 SMU.572 -93 4.6 TATAATATTTAAATATA
Streptococcus pneumoniae TIGR4 SP_0825 -98 6.3 TATAGTTTAAAGCTATA
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