Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of PflR regulog to Streptococcus pneumoniae SP14-BS69

Reference regulog properties
Source regulog: PflR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: DeoR
Regulation mode: repressor
Biological process: Formate metabolism
Effector:
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pneumoniae SP14-BS69
Orthologous TF(s) CGSSp14BS69_07935
Regulated genes 3
Built upon 28 sites [see more]
Predicted regulatory interactions in Streptococcus pneumoniae SP14-BS69
Locus tag Position Score Sequence
Position: -37
Score: 5.7
Sequence: AAGAAATAAAAATATTTTCGA
Position: -20
Score: 4.5
Sequence: TCGAAAGAAAGGTGCTTACGA
Locus tag: CGSSp14BS69_07905
CGSSp14BS69_07905 -37 5.7 AAGAAATAAAAATATTTTCGA
-20 4.5 TCGAAAGAAAGGTGCTTACGA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pflB
Ortholog function: Pyruvate formate-lyase (EC 2.3.1.54)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0175 -41 4.9 AAGAAACATTTATAATTTCGT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1808 -42 5.1 AAGAAAGTTATTTAATTTCGT
Streptococcus gordonii str. Challis substr. CH1 SGO_1788 -39 5.6 AAGAAATAAAAATAATTTCAT
Streptococcus mutans UA159 SMU.493 -41 5.1 AAGAAATTTAATATATTACGA
Streptococcus pneumoniae TIGR4 SP_0251 -37 5.7 AAGAAATAAAAATATTTTCGA
Streptococcus pyogenes M1 GAS SPy2049 -41 4.4 AAGAAACGTTTATAATTTCGT
Streptococcus sanguinis SK36 SSA_0285 -39 5.3 AAGAAATAAATTAAATTTCAT
Streptococcus uberis 0140J SUB0160 -42 5.3 AAGAAACAAAAATGTTTACGA
Position: -82
Score: 5.9
Sequence: ACGAAAGAAAAACAATTACGA
Locus tag: CGSSp14BS69_07935
CGSSp14BS69_07935 -82 5.9 ACGAAAGAAAAACAATTACGA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pflR
Ortholog function: Pyruvate-formate lyase operon transcriptional regulator, DeoR family
Streptococcus agalactiae 2603V/R SAG0326 -82 5.7 ACGTAACAAAGTCAATTACGA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0170 -80 6.1 ACGTAAATAAATCAATTACGA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1814 -83 6.1 ACGTAAATAAATCAATTACGA
Streptococcus gordonii str. Challis substr. CH1 SGO_1793 -79 5.8 ACGCAATAAATACAATTACGA
Streptococcus mutans UA159 SMU.491 -85 6 ACGAAACAAAATCAATTACGA
Streptococcus pneumoniae TIGR4 SP_0246 -82 5.9 ACGAAAGAAAAACAATTACGA
Streptococcus pyogenes M1 GAS SPy2054 -83 6.1 ACGTAAATAAATCAATTACGA
Streptococcus sanguinis SK36 SSA_0278 -85 5.6 TAGAAAGAAAAACAATTACGA
Streptococcus suis 05ZYH33 SSU05_0706 -91 4.9 AAGAAAGTTTTACAATTACGA
Streptococcus uberis 0140J SUB0157 -86 6 ACGTAAATAAATCAATTACGT
Position: -60
Score: 5.2
Sequence: TCGTAATTGTTTTTCTTTCGT
Locus tag: CGSSp14BS69_07940
CGSSp14BS69_07940 -60 5.2 TCGTAATTGTTTTTCTTTCGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pflA
Ortholog function: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4)
Streptococcus agalactiae 2603V/R SAG0325 -59 4.8 TCGTAATTGACTTTGTTACGT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0169 -63 5.8 TCGTAATTGATTTATTTACGT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1815 34 5.8 TCGTAATTGATTTATTTACGT
Streptococcus gordonii str. Challis substr. CH1 SGO_1794 -60 5.2 TCGTAATTGTATTTATTGCGT
Streptococcus mutans UA159 SMU.490 -66 5.1 TCGTAATTGATTTTGTTTCGT
Streptococcus pneumoniae TIGR4 SP_0245 -60 5.2 TCGTAATTGTTTTTCTTTCGT
Streptococcus pyogenes M1 GAS SPy2055 -63 5.8 TCGTAATTGATTTATTTACGT
Streptococcus sanguinis SK36 SSA_0277 -33 4.9 TCGTAATTGTTTTTCTTTCTA
Streptococcus suis 05ZYH33 SSU05_0705 -61 5 TCGTAATTGTAAAACTTTCTT
Streptococcus uberis 0140J SUB0156 -61 5.9 ACGTAATTGATTTATTTACGT
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