Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of CmbR regulog to Streptococcus pneumoniae SP19-BS75

Reference regulog properties
Source regulog: CmbR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LysR
Regulation mode: repressor (activator)
Biological process: Cysteine metabolism
Effector: O-acetyl-L-serine
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pneumoniae SP19-BS75
Orthologous TF(s) CGSSp19BS75_03732, CGSSp19BS75_05082
Regulated genes 4
Built upon 104 sites [see more]
Predicted regulatory interactions in Streptococcus pneumoniae SP19-BS75
Locus tag Position Score Sequence
Position: -251
Score: 4.5
Sequence: GTTATAGTCTTTTCTAATAAC
Position: -218
Score: 4.9
Sequence: CTTATAAGAATTACTAATAAC
Locus tag: CGSSp19BS75_05552
CGSSp19BS75_05552 -251 4.5 GTTATAGTCTTTTCTAATAAC
-218 4.9 CTTATAAGAATTACTAATAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Lactococcus lactis subsp. cremoris SK11 LACR_1368 -39 4.7 TTGATAAGATAGACCTATTAA
Lactococcus lactis subsp. lactis Il1403 L0100 -76 4.1 ATCATATTAAAAATGTATTAT
-39 4.7 TTGATAAGATAGACCTATTAA
Streptococcus agalactiae 2603V/R SAG2049 -109 4.1 GCTAAAAATATAAAATATTAA
Streptococcus gallolyticus UCN34 GALLO_1316 -221 4.2 ATAATAAATTTTATTAATCTA
-172 4.6 GTTATAGTTAAAAACTATAAT
Streptococcus gordonii str. Challis substr. CH1 SGO_0310 -182 4.2 GTTATAGTTTTTGATTATACC
Streptococcus mutans UA159 SMU.873 -188 4.6 GTTATAGATGAAAACTATAAC
Streptococcus pneumoniae TIGR4 SP_0585 -218 4.9 CTTATAAGAATTACTAATAAC
Streptococcus sanguinis SK36 SSA_0416 -182 4.3 GTCATAATTTCTACCTATAGC
Streptococcus suis 05ZYH33 SSU05_1774 -237 4.3 TTCATAGATAAAATCTATACC
Streptococcus thermophilus CNRZ1066 str0785 -119 4.2 GCTATACAAATATCTAATTAA
Position: -99
Score: 5.3
Sequence: CCCATAAAAAAAACTTATCAC
Locus tag: CGSSp19BS75_11243
CGSSp19BS75_11243 -99 5.3 CCCATAAAAAAAACTTATCAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: gshT
Ortholog function: Predicted glutathione ABC transporter, substrate-binding protein
Streptococcus mitis B6 smi_1946 -99 5.1 GCCATAAAGAAAACCTATCAC
Streptococcus pneumoniae TIGR4 SP_0148 -99 5.3 CCCATAAAAAAAACTTATCAC
Position: -142
Score: 5.2
Sequence: TTGATAGATAAAATATATAAC
Locus tag: CGSSp19BS75_06972
CGSSp19BS75_06972 -142 5.2 TTGATAGATAAAATATATAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyB
Ortholog function: Cystine ABC transporter, permease protein
Lactococcus lactis subsp. cremoris SK11 LACR_1010 -77 5.1 GCTATAAGTTTTTTTTATGGC
Lactococcus lactis subsp. lactis Il1403 L163056 -77 5.1 GCTATAAGTTTTTTTTATGGC
Streptococcus agalactiae 2603V/R SAG0291 -96 5.5 TTGATATAAAATCTTTATCAC
-75 4.7 CTGATAAGGAAATACTATTAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1719 -99 5.3 GTGATAAGTTTTGCTTATTGC
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1580 -106 5 GCGATAGGCTTTTCTTATCGT
Streptococcus gallolyticus UCN34 GALLO_0415 -100 5.2 CTGATAGTTTTTTCTTATCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0578 -170 4.7 GTCATAAAATTTGCTTATACC
-148 4.3 TTGATAAATAATTTATACTGT
Streptococcus mitis B6 smi_1382 -164 4.7 GAGATAGTTTTTACTTATCTC
-142 5 TTGATAGATAAAATATATAGC
Streptococcus mutans UA159 SMU.460 -102 5.8 GTGATAGAAAAATATTATCAC
-80 5 GTGATAGGAAAAAACTATTAT
Streptococcus pneumoniae TIGR4 SP_1461 -164 4.3 GAAATAGTTTTTATCTATCTC
-142 5.2 TTGATAGATAAAATATATAAC
Streptococcus sanguinis SK36 SSA_1868 -250 5.4 GTGATATACTTTTCTTATCGC
-228 5.3 GTGATAAGAAAAATATATTAG
Streptococcus thermophilus CNRZ1066 str1653 -217 5.8 GTGATATGATTTACTTATCAC
Streptococcus uberis 0140J SUB1415 -80 4.8 GTGATAGGCTTTAACTATTGC
Position: -103
Score: 5.2
Sequence: TCCATAAAAAATGTTTATCAC
Locus tag: CGSSp19BS75_02688
CGSSp19BS75_02688 -103 5.2 TCCATAAAAAATGTTTATCAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: yvdE
Ortholog function: Predicted glutamine amidotransferase, class I
Streptococcus gallolyticus UCN34 GALLO_1848 -98 5.2 GTGATAAAAAAAATCTATTGG
-61 5 AGGATAGAATAATCTTATCAC
Streptococcus gordonii str. Challis substr. CH1 SGO_0167 -97 5.5 TTGATAAAAAATTTTTATAAG
Streptococcus pneumoniae TIGR4 SP_2072 -64 5.2 TCCATAAAAAATGTTTATCAC
Streptococcus sanguinis SK36 SSA_2164 -100 5.8 CTGATAAAAAATTTTTATAAC
Streptococcus suis 05ZYH33 SSU05_1773 -95 5.3 CTGATAGTTATTTTTTATCAA