Propagation of Rex regulog to Streptococcus pneumoniae SP19-BS75

Reference regulog properties
Source regulog:	Rex - Streptococcaceae
Regulator type:	Transcription factor
Regulator family:	Rex
Regulation mode:	repressor
Biological process:	Energy metabolism
Effector:	NADH
Phylum:	Firmicutes
Propagated regulon:
Target genome	Streptococcus pneumoniae SP19-BS75
Orthologous TF(s)	CGSSp19BS75_02273
Regulated genes	12

Built upon 161 sites [see more]

Predicted regulatory interactions in *Streptococcus pneumoniae SP19-BS75*
	Locus tag	Position	Score	Sequence
Position: -62 Score: 4.5 Sequence: AAGTGATAAAATGAACAA Locus tag: CGSSp19BS75_05467
	CGSSp19BS75_05467	-62	4.5	AAGTGATAAAATGAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: fba
Ortholog function: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)
Streptococcus gallolyticus UCN34	GALLO_0255	-60	4.2	TTGTGATAAAATGTACGT
Streptococcus gordonii str. Challis substr. CH1	SGO_1745	-61	4.6	AAGTGATAAAATAAACAA
Streptococcus mutans UA159	SMU.99	-61	4.6	AAGTGATAAAATAAACAA
Streptococcus pneumoniae TIGR4	SP_0605	-62	4.5	AAGTGATAAAATGAACAA
Streptococcus sanguinis SK36	SSA_1992	-62	4.6	AAGTGATAAAATAAACAA

Position: -114 Score: 5.1 Sequence: TTGTGATATACTTCACAT Locus tag: CGSSp19BS75_11893
	CGSSp19BS75_11893	-114	5.1	TTGTGATATACTTCACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhB1
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
Streptococcus agalactiae 2603V/R	SAG0054	-118	4.4	TTAAGAATATTTTCAAAA
		-73	4.8	TTGTGAAGAATAATACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0062	-76	5.1	TTGTGAAAAGATATACAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0046	-80	5.1	TTGTGAAAAAGTATACAA
Streptococcus gordonii str. Challis substr. CH1	SGO_0565	-52	5.2	TTGTGATATAATTAACAT
Streptococcus mitis B6	smi_0275	-114	5.1	TTGTGATATACTTCACAT
Streptococcus pneumoniae TIGR4	SP_0285	-114	5.1	TTGTGATATACTTCACAT
Streptococcus pyogenes M1 GAS	SPy0044	-67	5	TTGTGAAAAGATGTACAA
Streptococcus sanguinis SK36	SSA_1917	-51	5.2	TTGTGATATAATTAACAT
Streptococcus suis 05ZYH33	SSU05_0279	-82	5.2	TTGTGATATTCTTAACAA

Position: -114 Score: 4.3 Sequence: TTGTTACTCTTTTCTCAA Locus tag: CGSSp19BS75_06837
	CGSSp19BS75_06837	-114	4.3	TTGTTACTCTTTTCTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pncB
Ortholog function: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)
Lactococcus lactis subsp. cremoris SK11	LACR_1202	-218	4	TTGTAGTATAAAAAACAT
Lactococcus lactis subsp. lactis Il1403	L107468	-181	3.9	TTGTAGTACAAAAAACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1714	-39	4.7	ATGTTATAATAGTAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1574	-39	4.3	ATGGTATAATAATAACAA
Streptococcus mitis B6	smi_1492	-114	4.3	TTGTTACTCTTTTCTCAA
Streptococcus mutans UA159	SMU.464	-265	4.3	GTGTTATAATAGTAACAA
Streptococcus pneumoniae TIGR4	SP_1421	-114	4.3	TTGTTACTCTTTTCTCAA
Streptococcus pyogenes M1 GAS	SPy1653	-39	4.7	ATGTTATAATAGTAACAA

Position: -55 Score: 4.2 Sequence: AAGTTACTCTTTTCACAA Locus tag: CGSSp19BS75_02368
	CGSSp19BS75_02368	-55	4.2	AAGTTACTCTTTTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: gap
Ortholog function: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
Streptococcus agalactiae 2603V/R	SAG1768	-76	4.4	AAGTTAATCTTTTCACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1936	-78	4.7	AAGTTAATCTTTTCACAA
Streptococcus gordonii str. Challis substr. CH1	SGO_0207	-158	4	ATTTGAAAGAATGAACAA
Streptococcus mutans UA159	SMU.360	-81	4.7	AAGTTAATCTTTTCACAA
Streptococcus pyogenes M1 GAS	SPy0274	-79	4.7	AAGTTAATCTTTTCACAA
Streptococcus sanguinis SK36	SSA_2108	-157	4.8	TAGTGAAAGAATTCATAA
Streptococcus thermophilus CNRZ1066	str1788	-50	4.7	AAGTTAATCTTTTCACAA
Streptococcus uberis 0140J	SUB1630	-78	4.7	AAGTTAATCTTTTCACAA

Position: -190 Score: 5.1 Sequence: TTGAAATAAATTTCACAA Position: -140 Score: 5.1 Sequence: ATGAGAAAAGTTTCACAA Position: -96 Score: 4.6 Sequence: TTATGAAACTGTTTACAA Position: -52 Score: 5.8 Sequence: TTGTGAAAAAATTAACAA Locus tag: CGSSp19BS75_02438
	CGSSp19BS75_02438	-190	5.1	TTGAAATAAATTTCACAA
		-140	5.1	ATGAGAAAAGTTTCACAA
		-96	4.6	TTATGAAACTGTTTACAA
		-52	5.8	TTGTGAAAAAATTAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhE
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)
Streptococcus agalactiae 2603V/R	SAG0053	-113	5.2	TTGAAAAAAAGTTCACAA
		-90	5.5	TTGTGAAACTATTTACAA
		-35	5.6	TTGTGAAACATTTAACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0061	-112	5.2	TTGAAAAAAACTTCACAA
		-89	5.4	TTGTGAAATGATTTACAA
		-34	5.5	TTGTGAAACTTTTAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0043	-112	5	TTGAAAAAAACATCACAA
		-89	5.4	TTGTGAAATGATTTACAA
		-34	5.5	TTGTGAAACTTTTAACAA
Streptococcus gordonii str. Challis substr. CH1	SGO_0113	-140	5.1	TTGAAATATATTTCACAA
		-51	5.8	TTGTGAAAAAATTAACAA
Streptococcus mitis B6	smi_0231	-209	4.5	TTGTGAAATAAAAAATAT
		-191	5.1	TTGAAATAATTTTCACAA
		-141	5.4	ATGAGAAAAATTTCACAA
		-97	4.6	TTATGAAACTGTTTACAA
		-53	5.8	TTGTGAAAAAATTAACAA
Streptococcus pneumoniae TIGR4	SP_2026	-208	4.5	TTGTGAAATAAAAAATAT
		-190	5.1	TTGAAATAAATTTCACAA
		-140	5.1	ATGAGAAAAGTTTCACAA
		-96	4.6	TTATGAAACTGTTTACAA
		-52	5.8	TTGTGAAAAAATTAACAA
Streptococcus sanguinis SK36	SSA_0068	-226	4.3	ATGTGAAATCTTTAAAAT
		-156	5	TTGTTATGTATTTCACAA
		-67	5.7	TTGTGAAATATTTAACAA
Streptococcus suis 05ZYH33	SSU05_0280	-129	4.5	TTGGGGAAAAGTTAACAA
Streptococcus uberis 0140J	SUB0063	-116	5.2	TTGAAAAAAAGTTCACAA
		-93	5.5	TTGTGAAACTATTTACAA
		-38	5.5	TTGTGAAACTTTTAACAA

Position: -96 Score: 5 Sequence: AAGTTAAAAAAATCACAA Locus tag: CGSSp19BS75_02598
	CGSSp19BS75_02598	-96	5	AAGTTAAAAAAATCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhB2
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
Streptococcus mitis B6	smi_0203	-95	5	AAGTTAAAAAAATCACAA
Streptococcus pneumoniae TIGR4	SP_2055	-96	5	AAGTTAAAAAAATCACAA

Position: -57 Score: 5 Sequence: TTGTTGATTTTTTCACAA Locus tag: CGSSp19BS75_02273
	CGSSp19BS75_02273	-57	5	TTGTTGATTTTTTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: rex
Ortholog function: Redox-sensitive transcriptional regulator Rex, Rex family
Lactococcus lactis subsp. cremoris SK11	LACR_1156	-74	5.3	TTGATAAAATTATCACAA
Lactococcus lactis subsp. lactis Il1403	L71932	-75	5.3	TTGATAAAATTATCACAA
Streptococcus agalactiae 2603V/R	SAG1100	-36	4.5	TAATAAAATTTTTAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1050	-31	4.4	TAGTTGCATATTTCACAA
Streptococcus gordonii str. Challis substr. CH1	SGO_1228	-54	4.7	TAGTTGATTTTTTCACAA
Streptococcus mitis B6	smi_1188	-57	5	TTGTTGATTTTTTCACAA
Streptococcus mutans UA159	SMU.1053	-117	4.4	TTGTTATAAAAAAAACTA
		-58	4.5	ATGTTGCATTTTTCACAA
Streptococcus pneumoniae TIGR4	SP_1090	-57	5	TTGTTGATTTTTTCACAA
Streptococcus pyogenes M1 GAS	SPy1120	-76	4.5	ATGTTGCATTTTTCACAA
Streptococcus sanguinis SK36	SSA_1216	-55	4.7	TAGTTGATTTTTTCACAA
Streptococcus suis 05ZYH33	SSU05_1069	-100	4.5	CTGTTGATTTTTTCACAA
Streptococcus thermophilus CNRZ1066	str1463	-39	4.6	TTGTTGCAATCTTCACAA
Streptococcus uberis 0140J	SUB0845	-52	4.4	TTGTTACAATAGTAACAT

Position: -28 Score: 5.1 Sequence: TTGATAAAAACATCACAA Locus tag: CGSSp19BS75_12463
	CGSSp19BS75_12463	-28	5.1	TTGATAAAAACATCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: hemH
Ortholog function: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1)
Streptococcus mitis B6	smi_1138	-28	5.1	TTGATAAAAACATCACAA
Streptococcus pneumoniae TIGR4	SP_1009	-28	5.1	TTGATAAAAACATCACAA

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of Rex regulog to Streptococcus pneumoniae SP19-BS75

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --