Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of CopR regulog to Lactococcus lactis subsp. cremoris SK11

Reference regulog properties
Source regulog: CopR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: CopY
Regulation mode: repressor
Biological process: Copper homeostasis
Effector: Copper ion, (Cu2+)
Phylum: Firmicutes
Propagated regulon:
Target genome Lactococcus lactis subsp. cremoris SK11
Orthologous TF(s) LACR_0889
Regulated genes 6
Built upon 39 sites [see more]
Predicted regulatory interactions in Lactococcus lactis subsp. cremoris SK11
Locus tag Position Score Sequence
Position: -45
Score: 5.9
Sequence: TCGTTTACAATTGTAAACAT
Locus tag: LACR_0072
LACR_0072 -45 5.9 TCGTTTACAATTGTAAACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yahC
Ortholog function: Hypothetical protein
Lactococcus lactis subsp. cremoris SK11 LACR_0072 -45 5.9 TCGTTTACAATTGTAAACAT
Lactococcus lactis subsp. lactis Il1403 L200005 -45 5.9 TCGTTTACAATTGTAAACAT
Position: -106
Score: 5.8
Sequence: ATGTTTACATGTGTAAATTT
Locus tag: LACR_0427
LACR_0427 -106 5.8 ATGTTTACATGTGTAAATTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ydiD
Ortholog function: FMN-dependent NADH-azoreductase
Lactococcus lactis subsp. cremoris SK11 LACR_0427 -106 5.8 ATGTTTACATGTGTAAATTT
Lactococcus lactis subsp. lactis Il1403 L186107 -106 5.8 ATGTTTACATGTGTAAATTT
Position: -53
Score: 5
Sequence: GTGTTTACGCGTGTAAACTT
Locus tag: LACR_0889
LACR_0889 -53 5 GTGTTTACGCGTGTAAACTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: copR
Ortholog function: Copper transport transcriptional regulator CopR, CopY family
Lactococcus lactis subsp. cremoris SK11 LACR_0889 -53 5 GTGTTTACGCGTGTAAACTT
Lactococcus lactis subsp. lactis Il1403 L45109 -53 5.5 GTGTTTACACGTGTAAACTT
Streptococcus agalactiae 2603V/R SAG0384 -66 5.8 CGGTTTACAAATGTAGATTT
-34 5.3 TGGTTTACAAACGTAAATCG
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1771 -73 5.7 TTATTTACAAATGTAGTTAA
-41 6.3 TAATTTACAAATGTAAATTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0447 -65 6.2 TTGTTTACAAATGTAAACAA
Streptococcus gallolyticus UCN34 GALLO_0378 -75 5.6 TCGTTGACAAATGTAAACGA
-43 5.7 AAATCTACAAATGTAAATCA
Streptococcus gordonii str. Challis substr. CH1 SGO_0289 -75 6.1 TTGTTTACAAATGTAAATGT
-34 6 AGATTTACAAATGTAGATTT
Streptococcus mitis B6 smi_1434 -73 6 TAGTTGACAAATGTAGATTT
-33 6 TAATTGACAAATGTAGATTT
Streptococcus mutans UA159 SMU.424 -63 5.8 TTGTTGACAAATGTAGACAA
-31 5.4 GTATCTACAAATGTAGATGA
Streptococcus pneumoniae TIGR4 SP_0727 -67 6 TAATTGACAAATGTAGATTT
-27 6 TAATTGACAAATGTAGATTT
Streptococcus pyogenes M1 GAS SPy1717 -73 5.7 TTATTTACAAATGTAGTTAA
-41 5.9 TAATTTACAAACGTAAATAT
Streptococcus thermophilus CNRZ1066 str1586 -100 5.3 AAATCTATAAATGTAGATAA
-46 5.9 AAATCTACAAATGTAAACAA
Streptococcus uberis 0140J SUB1464 -66 5.9 ATATTTACAATTGTAGATAT
-34 6.1 ATATTTACAAATGTAAACAA
Position: -54
Score: 6.1
Sequence: AAGTTTACAATTGTAAACTA
Locus tag: LACR_0891
LACR_0891 -54 6.1 AAGTTTACAATTGTAAACTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: copA
Ortholog function: Copper-translocating P-type ATPase (EC 3.6.3.4)
Lactococcus lactis subsp. cremoris SK11 LACR_0891 -54 6.1 AAGTTTACAATTGTAAACTA
Lactococcus lactis subsp. lactis Il1403 L45966 -53 5.5 GTGTTTACACGTGTAAACTT
Position: -65
Score: 5.6
Sequence: AGGTTTACAATCGTAAACTT
Locus tag: LACR_0920
LACR_0920 -65 5.6 AGGTTTACAATCGTAAACTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: copB
Ortholog function: Copper-translocating P-type ATPase (EC 3.6.3.4)
Lactococcus lactis subsp. cremoris SK11 LACR_0920 -65 5.6 AGGTTTACAATCGTAAACTT
Lactococcus lactis subsp. lactis Il1403 L70979 -62 6.1 TAGTTTACAATTGTAAACTA
Position: -72
Score: 6.2
Sequence: TAGTTTACAAGTGTAAATTT
Locus tag: LACR_2184
LACR_2184 -72 6.2 TAGTTTACAAGTGTAAATTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: cinD
Ortholog function: Copper-induced nitroreductase
Lactococcus lactis subsp. cremoris SK11 LACR_2184 -72 6.2 TAGTTTACAAGTGTAAATTT
-45 5.6 AAGATTACAGATGTAAACAA
Lactococcus lactis subsp. lactis Il1403 L174788 -73 6.2 TAGTTTACAAGTGTAAATTT
-46 5.6 AAGATTACATATGTAAACAA
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