Propagation of CmbR regulog to Lactococcus lactis subsp. cremoris SK11

Reference regulog properties
Source regulog:	CmbR - Streptococcaceae
Regulator type:	Transcription factor
Regulator family:	LysR
Regulation mode:	repressor (activator)
Biological process:	Cysteine metabolism
Effector:	O-acetyl-L-serine
Phylum:	Firmicutes
Propagated regulon:
Target genome	Lactococcus lactis subsp. cremoris SK11
Orthologous TF(s)	LACR_0375, LACR_1649
Regulated genes	8

Built upon 104 sites [see more]

Predicted regulatory interactions in *Lactococcus lactis subsp. cremoris SK11*
	Locus tag	Position	Score	Sequence
Position: -171 Score: 4.4 Sequence: ACTATTTAAAAATTCTATAAC Locus tag: LACR_0068
	LACR_0068	-171	4.4	ACTATTTAAAAATTCTATAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysD
Ortholog function: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49)
Lactococcus lactis subsp. cremoris SK11	LACR_0068	-171	4.4	ACTATTTAAAAATTCTATAAC
Lactococcus lactis subsp. lactis Il1403	L75975	-172	4.2	TCCATTAAAAAATCATATCGA

Position: -106 Score: 4.4 Sequence: TTTATTTGTTATTCTTATAGC Position: -77 Score: 5.1 Sequence: GCTATAAGTTTTTTTTATGGC Locus tag: LACR_1009
	LACR_1009	-106	4.4	TTTATTTGTTATTCTTATAGC
		-77	5.1	GCTATAAGTTTTTTTTATGGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyA
Ortholog function: Cystine ABC transporter, substrate-binding protein
Lactococcus lactis subsp. cremoris SK11	LACR_1009	-77	5.1	GCTATAAGTTTTTTTTATGGC
Lactococcus lactis subsp. lactis Il1403	L162009	-77	5.1	GCTATAAGTTTTTTTTATGGC
Streptococcus agalactiae 2603V/R	SAG0290	-96	5.5	TTGATATAAAATCTTTATCAC
		-75	4.7	CTGATAAGGAAATACTATTAT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1582	-98	4.7	TTGATACTATTTTCTTATTGC
		-76	4.2	TTGATAGAGAAATGATATTAT
Streptococcus gallolyticus UCN34	GALLO_0414	-100	5.2	CTGATAGTTTTTTCTTATCAA
Streptococcus mutans UA159	SMU.459	-102	5.8	GTGATAGAAAAATATTATCAC
		-80	5	GTGATAGGAAAAAACTATTAT
Streptococcus uberis 0140J	SUB1416	-98	4.5	GTCATATAAATAGCTAATTAC
		-76	4.2	TTGATAGAAAAATGGTATTAT

Position: -224 Score: 4.7 Sequence: GTAAAATAAATATTTTATAAT Locus tag: LACR_1010
	LACR_1010	-224	4.7	GTAAAATAAATATTTTATAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyB
Ortholog function: Cystine ABC transporter, permease protein
Lactococcus lactis subsp. cremoris SK11	LACR_1010	-77	5.1	GCTATAAGTTTTTTTTATGGC
Lactococcus lactis subsp. lactis Il1403	L163056	-77	5.1	GCTATAAGTTTTTTTTATGGC
Streptococcus agalactiae 2603V/R	SAG0291	-96	5.5	TTGATATAAAATCTTTATCAC
		-75	4.7	CTGATAAGGAAATACTATTAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1719	-99	5.3	GTGATAAGTTTTGCTTATTGC
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1580	-106	5	GCGATAGGCTTTTCTTATCGT
Streptococcus gallolyticus UCN34	GALLO_0415	-100	5.2	CTGATAGTTTTTTCTTATCAA
Streptococcus gordonii str. Challis substr. CH1	SGO_0578	-170	4.7	GTCATAAAATTTGCTTATACC
		-148	4.3	TTGATAAATAATTTATACTGT
Streptococcus mitis B6	smi_1382	-164	4.7	GAGATAGTTTTTACTTATCTC
		-142	5	TTGATAGATAAAATATATAGC
Streptococcus mutans UA159	SMU.460	-102	5.8	GTGATAGAAAAATATTATCAC
		-80	5	GTGATAGGAAAAAACTATTAT
Streptococcus pneumoniae TIGR4	SP_1461	-164	4.3	GAAATAGTTTTTATCTATCTC
		-142	5.2	TTGATAGATAAAATATATAAC
Streptococcus sanguinis SK36	SSA_1868	-250	5.4	GTGATATACTTTTCTTATCGC
		-228	5.3	GTGATAAGAAAAATATATTAG
Streptococcus thermophilus CNRZ1066	str1653	-217	5.8	GTGATATGATTTACTTATCAC
Streptococcus uberis 0140J	SUB1415	-80	4.8	GTGATAGGCTTTAACTATTGC

Position: -39 Score: 4.7 Sequence: TTGATAAGATAGACCTATTAA Locus tag: LACR_1368
	LACR_1368	-39	4.7	TTGATAAGATAGACCTATTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Lactococcus lactis subsp. cremoris SK11	LACR_1368	-39	4.7	TTGATAAGATAGACCTATTAA
Lactococcus lactis subsp. lactis Il1403	L0100	-76	4.1	ATCATATTAAAAATGTATTAT
		-39	4.7	TTGATAAGATAGACCTATTAA
Streptococcus agalactiae 2603V/R	SAG2049	-109	4.1	GCTAAAAATATAAAATATTAA
Streptococcus gallolyticus UCN34	GALLO_1316	-221	4.2	ATAATAAATTTTATTAATCTA
		-172	4.6	GTTATAGTTAAAAACTATAAT
Streptococcus gordonii str. Challis substr. CH1	SGO_0310	-182	4.2	GTTATAGTTTTTGATTATACC
Streptococcus mutans UA159	SMU.873	-188	4.6	GTTATAGATGAAAACTATAAC
Streptococcus pneumoniae TIGR4	SP_0585	-218	4.9	CTTATAAGAATTACTAATAAC
Streptococcus sanguinis SK36	SSA_0416	-182	4.3	GTCATAATTTCTACCTATAGC
Streptococcus suis 05ZYH33	SSU05_1774	-237	4.3	TTCATAGATAAAATCTATACC
Streptococcus thermophilus CNRZ1066	str0785	-119	4.2	GCTATACAAATATCTAATTAA

Position: -136 Score: 4.5 Sequence: ATCATAAATCTTTTTTATGGT Locus tag: LACR_2344
	LACR_2344	-136	4.5	ATCATAAATCTTTTTTATGGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: gshT
Ortholog function: Predicted glutathione ABC transporter, substrate-binding protein
Lactococcus lactis subsp. cremoris SK11	LACR_2344	-136	4.5	ATCATAAATCTTTTTTATGGT
Lactococcus lactis subsp. lactis Il1403	L121253	-136	4.7	GTCATAAATCTTTTTTATGGT

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of CmbR regulog to Lactococcus lactis subsp. cremoris SK11

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --