Propagation of CmbR regulog to Streptococcus pneumoniae G54

Reference regulog properties
Source regulog:	CmbR - Streptococcaceae
Regulator type:	Transcription factor
Regulator family:	LysR
Regulation mode:	repressor (activator)
Biological process:	Cysteine metabolism
Effector:	O-acetyl-L-serine
Phylum:	Firmicutes
Propagated regulon:
Target genome	Streptococcus pneumoniae G54
Orthologous TF(s)	SPG_0617, SPG_0853
Regulated genes	8

Built upon 104 sites [see more]

Predicted regulatory interactions in *Streptococcus pneumoniae G54*
	Locus tag	Position	Score	Sequence
Position: -99 Score: 5.3 Sequence: CCCATAAAAAAAACTTATCAC Locus tag: SPG_0150
	SPG_0150	-99	5.3	CCCATAAAAAAAACTTATCAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: gshT
Ortholog function: Predicted glutathione ABC transporter, substrate-binding protein
Streptococcus mitis B6	smi_1946	-99	5.1	GCCATAAAGAAAACCTATCAC
Streptococcus pneumoniae TIGR4	SP_0148	-99	5.3	CCCATAAAAAAAACTTATCAC

Position: -251 Score: 4.5 Sequence: GTTATAGTCTTTTCTAATAAC Position: -218 Score: 4.9 Sequence: CTTATAAGAATTACTAATAAC Locus tag: SPG_0534
	SPG_0534	-251	4.5	GTTATAGTCTTTTCTAATAAC
		-218	4.9	CTTATAAGAATTACTAATAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Lactococcus lactis subsp. cremoris SK11	LACR_1368	-39	4.7	TTGATAAGATAGACCTATTAA
Lactococcus lactis subsp. lactis Il1403	L0100	-76	4.1	ATCATATTAAAAATGTATTAT
		-39	4.7	TTGATAAGATAGACCTATTAA
Streptococcus agalactiae 2603V/R	SAG2049	-109	4.1	GCTAAAAATATAAAATATTAA
Streptococcus gallolyticus UCN34	GALLO_1316	-221	4.2	ATAATAAATTTTATTAATCTA
		-172	4.6	GTTATAGTTAAAAACTATAAT
Streptococcus gordonii str. Challis substr. CH1	SGO_0310	-182	4.2	GTTATAGTTTTTGATTATACC
Streptococcus mutans UA159	SMU.873	-188	4.6	GTTATAGATGAAAACTATAAC
Streptococcus pneumoniae TIGR4	SP_0585	-218	4.9	CTTATAAGAATTACTAATAAC
Streptococcus sanguinis SK36	SSA_0416	-182	4.3	GTCATAATTTCTACCTATAGC
Streptococcus suis 05ZYH33	SSU05_1774	-237	4.3	TTCATAGATAAAATCTATACC
Streptococcus thermophilus CNRZ1066	str0785	-119	4.2	GCTATACAAATATCTAATTAA

Position: -100 Score: 4.9 Sequence: ATGATTAAGTTTTTCTATCAC Locus tag: SPG_0563
	SPG_0563	-100	4.9	ATGATTAAGTTTTTCTATCAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: gshT
Ortholog function: Predicted glutathione ABC transporter, substrate-binding protein
Streptococcus gallolyticus UCN34	GALLO_1847	-98	5.2	GTGATAAAAAAAATCTATTGG
		-61	5	AGGATAGAATAATCTTATCAC
Streptococcus mitis B6	smi_1579	-101	5.1	ATGATTAAGTTTTTTTATCAC
Streptococcus pneumoniae TIGR4	SP_0620	-100	4.9	ATGATTAAGTTTTTCTATCAC
Streptococcus thermophilus CNRZ1066	str0908	-101	5.2	TTGATAGATATTGTTTATCAG

Position: -102 Score: 4.8 Sequence: ATGGTAAAAAATCCTTATAAC Position: -80 Score: 4.4 Sequence: GCAATAAAAAATAGATATTAT Locus tag: SPG_0645
	SPG_0645	-102	4.8	ATGGTAAAAAATCCTTATAAC
		-80	4.4	GCAATAAAAAATAGATATTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: str1582
Ortholog function: Predicted polar amino acid ABC transporter, permease protein 1
Streptococcus gallolyticus UCN34	GALLO_1237	-96	5.3	GCTATAAAAATTATTTATGGC
Streptococcus gordonii str. Challis substr. CH1	SGO_0985	-139	5.2	CTTATAAATTTTTTCTATCAG
		-117	4.9	CCGATAAAATATACATATTAT
Streptococcus mitis B6	smi_1436	-102	5.5	ATGATAAAAAATCCTTATAAC
		-80	4.4	GCAATAAAAAATAGATATTAT
Streptococcus pneumoniae TIGR4	SP_0711	-140	4.4	GCAATAAAAAATAGATATTAT
Streptococcus thermophilus CNRZ1066	str1582	-237	4.8	GTTATATCTTTTCTTTATCAC
		-215	5.2	TTGATAAAAAATACATATTAT

Position: -142 Score: 5.2 Sequence: TTGATAGATAAAATATATAAC Locus tag: SPG_1387
	SPG_1387	-142	5.2	TTGATAGATAAAATATATAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyB
Ortholog function: Cystine ABC transporter, permease protein
Lactococcus lactis subsp. cremoris SK11	LACR_1010	-77	5.1	GCTATAAGTTTTTTTTATGGC
Lactococcus lactis subsp. lactis Il1403	L163056	-77	5.1	GCTATAAGTTTTTTTTATGGC
Streptococcus agalactiae 2603V/R	SAG0291	-96	5.5	TTGATATAAAATCTTTATCAC
		-75	4.7	CTGATAAGGAAATACTATTAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1719	-99	5.3	GTGATAAGTTTTGCTTATTGC
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1580	-106	5	GCGATAGGCTTTTCTTATCGT
Streptococcus gallolyticus UCN34	GALLO_0415	-100	5.2	CTGATAGTTTTTTCTTATCAA
Streptococcus gordonii str. Challis substr. CH1	SGO_0578	-170	4.7	GTCATAAAATTTGCTTATACC
		-148	4.3	TTGATAAATAATTTATACTGT
Streptococcus mitis B6	smi_1382	-164	4.7	GAGATAGTTTTTACTTATCTC
		-142	5	TTGATAGATAAAATATATAGC
Streptococcus mutans UA159	SMU.460	-102	5.8	GTGATAGAAAAATATTATCAC
		-80	5	GTGATAGGAAAAAACTATTAT
Streptococcus pneumoniae TIGR4	SP_1461	-164	4.3	GAAATAGTTTTTATCTATCTC
		-142	5.2	TTGATAGATAAAATATATAAC
Streptococcus sanguinis SK36	SSA_1868	-250	5.4	GTGATATACTTTTCTTATCGC
		-228	5.3	GTGATAAGAAAAATATATTAG
Streptococcus thermophilus CNRZ1066	str1653	-217	5.8	GTGATATGATTTACTTATCAC
Streptococcus uberis 0140J	SUB1415	-80	4.8	GTGATAGGCTTTAACTATTGC

Position: -145 Score: 4.6 Sequence: GATATAAAAATAGACTATAAC Locus tag: SPG_1502
	SPG_1502	-145	4.6	GATATAAAAATAGACTATAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: metA
Ortholog function: Homoserine O-succinyltransferase (EC 2.3.1.46)
Lactococcus lactis subsp. lactis Il1403	L0101	-132	4.3	GCCATAGGCAAGTTTTATTAT
Streptococcus gallolyticus UCN34	GALLO_0824	-107	4.3	ATTATAGCTAAAAACTATAAC
Streptococcus pneumoniae TIGR4	SP_1576	-145	4.6	GATATAAAAATAGACTATAAC
Streptococcus suis 05ZYH33	SSU05_1306	-46	4.7	GTTATAGCCAAAACTTATAAC

Position: -103 Score: 5.2 Sequence: TCCATAAAAAATGTTTATCAC Locus tag: SPG_2011
	SPG_2011	-103	5.2	TCCATAAAAAATGTTTATCAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: yvdE
Ortholog function: Predicted glutamine amidotransferase, class I
Streptococcus gallolyticus UCN34	GALLO_1848	-98	5.2	GTGATAAAAAAAATCTATTGG
		-61	5	AGGATAGAATAATCTTATCAC
Streptococcus gordonii str. Challis substr. CH1	SGO_0167	-97	5.5	TTGATAAAAAATTTTTATAAG
Streptococcus pneumoniae TIGR4	SP_2072	-64	5.2	TCCATAAAAAATGTTTATCAC
Streptococcus sanguinis SK36	SSA_2164	-100	5.8	CTGATAAAAAATTTTTATAAC
Streptococcus suis 05ZYH33	SSU05_1773	-95	5.3	CTGATAGTTATTTTTTATCAA

Position: -98 Score: 4.6 Sequence: GATATATAGAAATCCTATCGC Locus tag: SPG_2156
	SPG_2156	-98	4.6	GATATATAGAAATCCTATCGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysK
Ortholog function: Cysteine synthase (EC 2.5.1.47)
Lactococcus lactis subsp. lactis Il1403	L0089	-79	5.3	GCTATAAAAAAATCTTATAGC
Lactococcus lactis subsp. lactis Il1403	L0088	-87	4.5	ATCATAAATTTTTTTTAGAGC
Streptococcus mitis B6	smi_2060	-98	5.3	GATATAAAAAAATCCTATCAC
Streptococcus thermophilus CNRZ1066	str0366	-16	5.2	ATGATAAAATTTTTTTATGGA
Streptococcus uberis 0140J	SUB1379	-104	5.1	ATGATAAGCCTTTCCTATCAC

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of CmbR regulog to Streptococcus pneumoniae G54

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --