Propagation of Rex regulog to Streptococcus pneumoniae TIGR4

Reference regulog properties
Source regulog:	Rex - Streptococcaceae
Regulator type:	Transcription factor
Regulator family:	Rex
Regulation mode:	repressor
Biological process:	Energy metabolism
Effector:	NADH
Phylum:	Firmicutes
Propagated regulon:
Target genome	Streptococcus pneumoniae TIGR4
Orthologous TF(s)	SP_1090
Regulated genes	12

Built upon 161 sites [see more]

Predicted regulatory interactions in *Streptococcus pneumoniae TIGR4*
	Locus tag	Position	Score	Sequence
Position: -114 Score: 5.1 Sequence: TTGTGATATACTTCACAT Locus tag: SP_0285
	SP_0285	-114	5.1	TTGTGATATACTTCACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhB1
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
Streptococcus agalactiae 2603V/R	SAG0054	-118	4.4	TTAAGAATATTTTCAAAA
		-73	4.8	TTGTGAAGAATAATACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0062	-76	5.1	TTGTGAAAAGATATACAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0046	-80	5.1	TTGTGAAAAAGTATACAA
Streptococcus gordonii str. Challis substr. CH1	SGO_0565	-52	5.2	TTGTGATATAATTAACAT
Streptococcus mitis B6	smi_0275	-114	5.1	TTGTGATATACTTCACAT
Streptococcus pneumoniae TIGR4	SP_0285	-114	5.1	TTGTGATATACTTCACAT
Streptococcus pyogenes M1 GAS	SPy0044	-67	5	TTGTGAAAAGATGTACAA
Streptococcus sanguinis SK36	SSA_1917	-51	5.2	TTGTGATATAATTAACAT
Streptococcus suis 05ZYH33	SSU05_0279	-82	5.2	TTGTGATATTCTTAACAA

Position: -62 Score: 4.5 Sequence: AAGTGATAAAATGAACAA Locus tag: SP_0605
	SP_0605	-62	4.5	AAGTGATAAAATGAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: fba
Ortholog function: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)
Streptococcus gallolyticus UCN34	GALLO_0255	-60	4.2	TTGTGATAAAATGTACGT
Streptococcus gordonii str. Challis substr. CH1	SGO_1745	-61	4.6	AAGTGATAAAATAAACAA
Streptococcus mutans UA159	SMU.99	-61	4.6	AAGTGATAAAATAAACAA
Streptococcus pneumoniae TIGR4	SP_0605	-62	4.5	AAGTGATAAAATGAACAA
Streptococcus sanguinis SK36	SSA_1992	-62	4.6	AAGTGATAAAATAAACAA

Position: -28 Score: 5.1 Sequence: TTGATAAAAACATCACAA Locus tag: SP_1009
	SP_1009	-28	5.1	TTGATAAAAACATCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: hemH
Ortholog function: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1)
Streptococcus mitis B6	smi_1138	-28	5.1	TTGATAAAAACATCACAA
Streptococcus pneumoniae TIGR4	SP_1009	-28	5.1	TTGATAAAAACATCACAA

Position: -94 Score: 5.2 Sequence: TTGTGAAAATAATCTCAA Locus tag: SP_1119
	SP_1119	-94	5.2	TTGTGAAAATAATCTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: gapN
Ortholog function: Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
Streptococcus pneumoniae TIGR4	SP_1119	-94	5.2	TTGTGAAAATAATCTCAA
Streptococcus sanguinis SK36	SSA_0774	-91	4.5	TTGTGAAAAAATTCTTTA

Position: -114 Score: 4.3 Sequence: TTGTTACTCTTTTCTCAA Locus tag: SP_1421
	SP_1421	-114	4.3	TTGTTACTCTTTTCTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pncB
Ortholog function: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)
Lactococcus lactis subsp. cremoris SK11	LACR_1202	-218	4	TTGTAGTATAAAAAACAT
Lactococcus lactis subsp. lactis Il1403	L107468	-181	3.9	TTGTAGTACAAAAAACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1714	-39	4.7	ATGTTATAATAGTAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1574	-39	4.3	ATGGTATAATAATAACAA
Streptococcus mitis B6	smi_1492	-114	4.3	TTGTTACTCTTTTCTCAA
Streptococcus mutans UA159	SMU.464	-265	4.3	GTGTTATAATAGTAACAA
Streptococcus pneumoniae TIGR4	SP_1421	-114	4.3	TTGTTACTCTTTTCTCAA
Streptococcus pyogenes M1 GAS	SPy1653	-39	4.7	ATGTTATAATAGTAACAA

Position: -193 Score: 4.4 Sequence: AAGTTAGAATTTTCACAA Locus tag: SP_1469
	SP_1469	-193	4.4	AAGTTAGAATTTTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: noxE
Ortholog function: NADH oxidase (EC 1.6.99.3)
Streptococcus agalactiae 2603V/R	SAG0958	-165	4.3	TTGTGAATTTGTGAAAAA
		-59	4.7	TTGTGAATAATGTTATAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0909	-23	4.6	TTGTGAAATGAGGAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1023	-81	4.3	TTGTGAAATGAGGAACAT
Streptococcus pyogenes M1 GAS	SPy1150	-23	4.6	TTGTGAAATGAGGAACAA
Streptococcus thermophilus CNRZ1066	str1281	-91	4.6	TTGTTCAAAAAGTAACAA
Streptococcus uberis 0140J	SUB0877	-170	4.6	TTGTGAATTTATGAACTA
		-24	4.7	TTGTGAAAAGAGGAACAA

Position: -55 Score: 4.2 Sequence: AAGTTACTCTTTTCACAA Locus tag: SP_2012
	SP_2012	-55	4.2	AAGTTACTCTTTTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: gap
Ortholog function: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
Streptococcus agalactiae 2603V/R	SAG1768	-76	4.4	AAGTTAATCTTTTCACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1936	-78	4.7	AAGTTAATCTTTTCACAA
Streptococcus gordonii str. Challis substr. CH1	SGO_0207	-158	4	ATTTGAAAGAATGAACAA
Streptococcus mutans UA159	SMU.360	-81	4.7	AAGTTAATCTTTTCACAA
Streptococcus pyogenes M1 GAS	SPy0274	-79	4.7	AAGTTAATCTTTTCACAA
Streptococcus sanguinis SK36	SSA_2108	-157	4.8	TAGTGAAAGAATTCATAA
Streptococcus thermophilus CNRZ1066	str1788	-50	4.7	AAGTTAATCTTTTCACAA
Streptococcus uberis 0140J	SUB1630	-78	4.7	AAGTTAATCTTTTCACAA

Position: -208 Score: 4.5 Sequence: TTGTGAAATAAAAAATAT Position: -190 Score: 5.1 Sequence: TTGAAATAAATTTCACAA Position: -140 Score: 5.1 Sequence: ATGAGAAAAGTTTCACAA Position: -96 Score: 4.6 Sequence: TTATGAAACTGTTTACAA Position: -52 Score: 5.8 Sequence: TTGTGAAAAAATTAACAA Locus tag: SP_2026
	SP_2026	-208	4.5	TTGTGAAATAAAAAATAT
		-190	5.1	TTGAAATAAATTTCACAA
		-140	5.1	ATGAGAAAAGTTTCACAA
		-96	4.6	TTATGAAACTGTTTACAA
		-52	5.8	TTGTGAAAAAATTAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhE
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)
Streptococcus agalactiae 2603V/R	SAG0053	-113	5.2	TTGAAAAAAAGTTCACAA
		-90	5.5	TTGTGAAACTATTTACAA
		-35	5.6	TTGTGAAACATTTAACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0061	-112	5.2	TTGAAAAAAACTTCACAA
		-89	5.4	TTGTGAAATGATTTACAA
		-34	5.5	TTGTGAAACTTTTAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0043	-112	5	TTGAAAAAAACATCACAA
		-89	5.4	TTGTGAAATGATTTACAA
		-34	5.5	TTGTGAAACTTTTAACAA
Streptococcus gordonii str. Challis substr. CH1	SGO_0113	-140	5.1	TTGAAATATATTTCACAA
		-51	5.8	TTGTGAAAAAATTAACAA
Streptococcus mitis B6	smi_0231	-209	4.5	TTGTGAAATAAAAAATAT
		-191	5.1	TTGAAATAATTTTCACAA
		-141	5.4	ATGAGAAAAATTTCACAA
		-97	4.6	TTATGAAACTGTTTACAA
		-53	5.8	TTGTGAAAAAATTAACAA
Streptococcus pneumoniae TIGR4	SP_2026	-208	4.5	TTGTGAAATAAAAAATAT
		-190	5.1	TTGAAATAAATTTCACAA
		-140	5.1	ATGAGAAAAGTTTCACAA
		-96	4.6	TTATGAAACTGTTTACAA
		-52	5.8	TTGTGAAAAAATTAACAA
Streptococcus sanguinis SK36	SSA_0068	-226	4.3	ATGTGAAATCTTTAAAAT
		-156	5	TTGTTATGTATTTCACAA
		-67	5.7	TTGTGAAATATTTAACAA
Streptococcus suis 05ZYH33	SSU05_0280	-129	4.5	TTGGGGAAAAGTTAACAA
Streptococcus uberis 0140J	SUB0063	-116	5.2	TTGAAAAAAAGTTCACAA
		-93	5.5	TTGTGAAACTATTTACAA
		-38	5.5	TTGTGAAACTTTTAACAA

Position: -96 Score: 5 Sequence: AAGTTAAAAAAATCACAA Locus tag: SP_2055
	SP_2055	-96	5	AAGTTAAAAAAATCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhB2
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
Streptococcus mitis B6	smi_0203	-95	5	AAGTTAAAAAAATCACAA
Streptococcus pneumoniae TIGR4	SP_2055	-96	5	AAGTTAAAAAAATCACAA

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of Rex regulog to Streptococcus pneumoniae TIGR4

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --