Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of Rex regulog to Streptococcus pneumoniae TIGR4

Reference regulog properties
Source regulog: Rex - Streptococcaceae
Regulator type: Transcription factor
Regulator family: Rex
Regulation mode: repressor
Biological process: Energy metabolism
Effector: NADH
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pneumoniae TIGR4
Orthologous TF(s) SP_1090
Regulated genes 12
Built upon 161 sites [see more]
Predicted regulatory interactions in Streptococcus pneumoniae TIGR4
Locus tag Position Score Sequence
Position: -114
Score: 5.1
Sequence: TTGTGATATACTTCACAT
Locus tag: SP_0285
SP_0285 -114 5.1 TTGTGATATACTTCACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhB1
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
Streptococcus agalactiae 2603V/R SAG0054 -118 4.4 TTAAGAATATTTTCAAAA
-73 4.8 TTGTGAAGAATAATACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0062 -76 5.1 TTGTGAAAAGATATACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0046 -80 5.1 TTGTGAAAAAGTATACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0565 -52 5.2 TTGTGATATAATTAACAT
Streptococcus mitis B6 smi_0275 -114 5.1 TTGTGATATACTTCACAT
Streptococcus pneumoniae TIGR4 SP_0285 -114 5.1 TTGTGATATACTTCACAT
Streptococcus pyogenes M1 GAS SPy0044 -67 5 TTGTGAAAAGATGTACAA
Streptococcus sanguinis SK36 SSA_1917 -51 5.2 TTGTGATATAATTAACAT
Streptococcus suis 05ZYH33 SSU05_0279 -82 5.2 TTGTGATATTCTTAACAA
Position: -62
Score: 4.5
Sequence: AAGTGATAAAATGAACAA
Locus tag: SP_0605
SP_0605 -62 4.5 AAGTGATAAAATGAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: fba
Ortholog function: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)
Streptococcus gallolyticus UCN34 GALLO_0255 -60 4.2 TTGTGATAAAATGTACGT
Streptococcus gordonii str. Challis substr. CH1 SGO_1745 -61 4.6 AAGTGATAAAATAAACAA
Streptococcus mutans UA159 SMU.99 -61 4.6 AAGTGATAAAATAAACAA
Streptococcus pneumoniae TIGR4 SP_0605 -62 4.5 AAGTGATAAAATGAACAA
Streptococcus sanguinis SK36 SSA_1992 -62 4.6 AAGTGATAAAATAAACAA
Position: -28
Score: 5.1
Sequence: TTGATAAAAACATCACAA
Locus tag: SP_1009
SP_1009 -28 5.1 TTGATAAAAACATCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: hemH
Ortholog function: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1)
Streptococcus mitis B6 smi_1138 -28 5.1 TTGATAAAAACATCACAA
Streptococcus pneumoniae TIGR4 SP_1009 -28 5.1 TTGATAAAAACATCACAA
Position: -94
Score: 5.2
Sequence: TTGTGAAAATAATCTCAA
Locus tag: SP_1119
SP_1119 -94 5.2 TTGTGAAAATAATCTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: gapN
Ortholog function: Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
Streptococcus pneumoniae TIGR4 SP_1119 -94 5.2 TTGTGAAAATAATCTCAA
Streptococcus sanguinis SK36 SSA_0774 -91 4.5 TTGTGAAAAAATTCTTTA
Position: -114
Score: 4.3
Sequence: TTGTTACTCTTTTCTCAA
Locus tag: SP_1421
SP_1421 -114 4.3 TTGTTACTCTTTTCTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pncB
Ortholog function: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)
Lactococcus lactis subsp. cremoris SK11 LACR_1202 -218 4 TTGTAGTATAAAAAACAT
Lactococcus lactis subsp. lactis Il1403 L107468 -181 3.9 TTGTAGTACAAAAAACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1714 -39 4.7 ATGTTATAATAGTAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1574 -39 4.3 ATGGTATAATAATAACAA
Streptococcus mitis B6 smi_1492 -114 4.3 TTGTTACTCTTTTCTCAA
Streptococcus mutans UA159 SMU.464 -265 4.3 GTGTTATAATAGTAACAA
Streptococcus pneumoniae TIGR4 SP_1421 -114 4.3 TTGTTACTCTTTTCTCAA
Streptococcus pyogenes M1 GAS SPy1653 -39 4.7 ATGTTATAATAGTAACAA
Position: -193
Score: 4.4
Sequence: AAGTTAGAATTTTCACAA
Locus tag: SP_1469
SP_1469 -193 4.4 AAGTTAGAATTTTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: noxE
Ortholog function: NADH oxidase (EC 1.6.99.3)
Streptococcus agalactiae 2603V/R SAG0958 -165 4.3 TTGTGAATTTGTGAAAAA
-59 4.7 TTGTGAATAATGTTATAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0909 -23 4.6 TTGTGAAATGAGGAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1023 -81 4.3 TTGTGAAATGAGGAACAT
Streptococcus pyogenes M1 GAS SPy1150 -23 4.6 TTGTGAAATGAGGAACAA
Streptococcus thermophilus CNRZ1066 str1281 -91 4.6 TTGTTCAAAAAGTAACAA
Streptococcus uberis 0140J SUB0877 -170 4.6 TTGTGAATTTATGAACTA
-24 4.7 TTGTGAAAAGAGGAACAA
Position: -55
Score: 4.2
Sequence: AAGTTACTCTTTTCACAA
Locus tag: SP_2012
SP_2012 -55 4.2 AAGTTACTCTTTTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: gap
Ortholog function: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
Streptococcus agalactiae 2603V/R SAG1768 -76 4.4 AAGTTAATCTTTTCACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1936 -78 4.7 AAGTTAATCTTTTCACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0207 -158 4 ATTTGAAAGAATGAACAA
Streptococcus mutans UA159 SMU.360 -81 4.7 AAGTTAATCTTTTCACAA
Streptococcus pyogenes M1 GAS SPy0274 -79 4.7 AAGTTAATCTTTTCACAA
Streptococcus sanguinis SK36 SSA_2108 -157 4.8 TAGTGAAAGAATTCATAA
Streptococcus thermophilus CNRZ1066 str1788 -50 4.7 AAGTTAATCTTTTCACAA
Streptococcus uberis 0140J SUB1630 -78 4.7 AAGTTAATCTTTTCACAA
Position: -208
Score: 4.5
Sequence: TTGTGAAATAAAAAATAT
Position: -190
Score: 5.1
Sequence: TTGAAATAAATTTCACAA
Position: -140
Score: 5.1
Sequence: ATGAGAAAAGTTTCACAA
Position: -96
Score: 4.6
Sequence: TTATGAAACTGTTTACAA
Position: -52
Score: 5.8
Sequence: TTGTGAAAAAATTAACAA
Locus tag: SP_2026
SP_2026 -208 4.5 TTGTGAAATAAAAAATAT
-190 5.1 TTGAAATAAATTTCACAA
-140 5.1 ATGAGAAAAGTTTCACAA
-96 4.6 TTATGAAACTGTTTACAA
-52 5.8 TTGTGAAAAAATTAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhE
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)
Streptococcus agalactiae 2603V/R SAG0053 -113 5.2 TTGAAAAAAAGTTCACAA
-90 5.5 TTGTGAAACTATTTACAA
-35 5.6 TTGTGAAACATTTAACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0061 -112 5.2 TTGAAAAAAACTTCACAA
-89 5.4 TTGTGAAATGATTTACAA
-34 5.5 TTGTGAAACTTTTAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0043 -112 5 TTGAAAAAAACATCACAA
-89 5.4 TTGTGAAATGATTTACAA
-34 5.5 TTGTGAAACTTTTAACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0113 -140 5.1 TTGAAATATATTTCACAA
-51 5.8 TTGTGAAAAAATTAACAA
Streptococcus mitis B6 smi_0231 -209 4.5 TTGTGAAATAAAAAATAT
-191 5.1 TTGAAATAATTTTCACAA
-141 5.4 ATGAGAAAAATTTCACAA
-97 4.6 TTATGAAACTGTTTACAA
-53 5.8 TTGTGAAAAAATTAACAA
Streptococcus pneumoniae TIGR4 SP_2026 -208 4.5 TTGTGAAATAAAAAATAT
-190 5.1 TTGAAATAAATTTCACAA
-140 5.1 ATGAGAAAAGTTTCACAA
-96 4.6 TTATGAAACTGTTTACAA
-52 5.8 TTGTGAAAAAATTAACAA
Streptococcus sanguinis SK36 SSA_0068 -226 4.3 ATGTGAAATCTTTAAAAT
-156 5 TTGTTATGTATTTCACAA
-67 5.7 TTGTGAAATATTTAACAA
Streptococcus suis 05ZYH33 SSU05_0280 -129 4.5 TTGGGGAAAAGTTAACAA
Streptococcus uberis 0140J SUB0063 -116 5.2 TTGAAAAAAAGTTCACAA
-93 5.5 TTGTGAAACTATTTACAA
-38 5.5 TTGTGAAACTTTTAACAA
Position: -96
Score: 5
Sequence: AAGTTAAAAAAATCACAA
Locus tag: SP_2055
SP_2055 -96 5 AAGTTAAAAAAATCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhB2
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
Streptococcus mitis B6 smi_0203 -95 5 AAGTTAAAAAAATCACAA
Streptococcus pneumoniae TIGR4 SP_2055 -96 5 AAGTTAAAAAAATCACAA