Propagation of CtsR regulog to Streptococcus pyogenes MGAS10750
| Source regulog: | CtsR - Streptococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | CtsR |
| Regulation mode: | repressor |
| Biological process: | Heat shock response |
| Effector: | Heat shock |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Streptococcus pyogenes MGAS10750 |
| Orthologous TF(s) | MGAS10750_Spy1858 |
| Regulated genes | 4 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -125
Score: 6.6 Sequence: TATGATTTGACCTTTATTGACCAA
Locus tag: MGAS10750_Spy0324
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| MGAS10750_Spy0324 | -125 | 6.6 | TATGATTTGACCTTTATTGACCAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: clpP | ||||
| Ortholog function: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_0700 | -110 | 6.8 | TTTTCTTTGACCTTTTTTGACCAA |
| Lactococcus lactis subsp. lactis Il1403 | L72391 | -110 | 6.8 | TATTCTTTGACCTTTTTTGACCAA |
| Streptococcus agalactiae 2603V/R | SAG1585 | -67 | 6.6 | TATTATTTGACCTTTGTTGACCAA |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0439 | -125 | 6.5 | TATCATTTGACCTTTCTTGACCAA |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1614 | -93 | 6.8 | TATCATTTGACCTTTTTTGACCAA |
| Streptococcus gallolyticus UCN34 | GALLO_1763 | -127 | 7 | TTTTATTTGACCTTTTTTGACCAA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1632 | -103 | 6.6 | AAAAATTTGACCTTTATTGACCAA |
| Streptococcus mitis B6 | smi_1417 | -89 | 6.8 | AAAAATTTGACCTTTTTTGACCAA |
| Streptococcus mutans UA159 | SMU.1672 | -68 | 6.8 | AAATATTTGACCTTTTTTGACCAA |
| Streptococcus pneumoniae TIGR4 | SP_0746 | -89 | 6.8 | AAAAATTTGACCTTTTTTGACCAA |
| Streptococcus pyogenes M1 GAS | SPy0395 | -125 | 6.6 | TATGATTTGACCTTTATTGACCAA |
| Streptococcus sanguinis SK36 | SSA_1731 | -103 | 6.6 | TTCTATTTGACCTTTTTTGACCAA |
| Streptococcus suis 05ZYH33 | SSU05_1550 | -67 | 6.1 | TTTTTATTGACCAATTTTGACTAT |
| Streptococcus thermophilus CNRZ1066 | str0356 | -67 | 6.2 | TTTTATTTGACCTAATTTGACTAA |
| Streptococcus uberis 0140J | SUB0429 | -98 | 6.7 | TATTATTTGACCTTATTTGACCAA |
|
Position: -172
Score: 5.8 Sequence: TTTTGTTTCACCTTTACTGACCTT
Locus tag: MGAS10750_Spy0786
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| MGAS10750_Spy0786 | -172 | 5.8 | TTTTGTTTCACCTTTACTGACCTT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: clpL | ||||
| Ortholog function: ATP-dependent Clp protease, ATP-binding subunit | ||||
| Streptococcus agalactiae 2603V/R | SAG1303 | -144 | 6.3 | TATTTATTGACCTTTACTGACTAA |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0851 | -180 | 6.4 | TTTTGTTTGACCTTAACTGACCAA |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1072 | -181 | 6.3 | TTTTGTTTGACCTTTACTGACCTT |
| Streptococcus gallolyticus UCN34 | GALLO_1249 | -190 | 6.6 | AAATATTTGACTTTTACTGACCAA |
| Streptococcus mitis B6 | smi_1765 | -276 | 6.3 | AAATCCTTGACCTTTTCTGACTAA |
| Streptococcus pneumoniae TIGR4 | SP_0338 | -275 | 6.5 | AAACTCTTGACCTTTTCTGACCAA |
| Streptococcus pyogenes M1 GAS | SPy0888 | -172 | 6.3 | TTTTGTTTGACCTTTACTGACCTT |
| Streptococcus suis 05ZYH33 | SSU05_0389 | -254 | 6.1 | AAACTATTGACTTTTACTGACCAA |
| Streptococcus suis 05ZYH33 | SSU05_0390 | -254 | 6.1 | AAACTATTGACTTTTACTGACCAA |
| Streptococcus suis 05ZYH33 | SSU05_0391 | -254 | 6.1 | AAACTATTGACTTTTACTGACCAA |
| Streptococcus thermophilus CNRZ1066 | str1614 | -84 | -0.1 | TTGGTCAGTAAAAGTCAATTTTTA |
| Streptococcus uberis 0140J | SUB0776 | -152 | 6.9 | TTTTTCTTGACCTTTTTTGACCAA |
|
Position: -62
Score: 6.7 Sequence: TAAAGTTTGACCATTTTTGACTAA
Locus tag: MGAS10750_Spy1347
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| MGAS10750_Spy1347 | -62 | 6.7 | TAAAGTTTGACCATTTTTGACTAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: clpE | ||||
| Ortholog function: ATP-dependent Clp protease, ATP-binding subunit ClpE | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_0578 | -119 | -0.4 | ATGGTCAAATATGGTCAAGCTTTT |
| Lactococcus lactis subsp. lactis Il1403 | L0221 | -117 | -0.9 | ATGGTCAAATATGGTCAAACTTTT |
| Streptococcus agalactiae 2603V/R | SAG0488 | -65 | 6.3 | TAAAGTTTGACTATATTTGACTAT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1496 | -62 | 6.7 | TAAAGTTTGACCATTTTTGACTAA |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0605 | -63 | 6.7 | TAAAGTTTGACCATTTTTGACTAA |
| Streptococcus gallolyticus UCN34 | GALLO_0612 | -65 | 5.7 | TGAAGTTTGACTATCTTTGACCTT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0688 | -65 | 6.9 | TAAAGTTTGACTATTTTTGACCAA |
| Streptococcus mitis B6 | smi_0865 | -62 | 6.3 | TAGAATTTGACTATTTTTGACCTT |
| Streptococcus mutans UA159 | SMU.562 | -74 | 6.6 | TAAAGTTTGACCATTATTGACCAT |
| Streptococcus pneumoniae TIGR4 | SP_0820 | -62 | 6.3 | TAGAATTTGACTATTTTTGACCTT |
| Streptococcus pyogenes M1 GAS | SPy1509 | -62 | 6.7 | TAAAGTTTGACCATTTTTGACTAA |
| Streptococcus sanguinis SK36 | SSA_0669 | -73 | 6.2 | AAAACTTTGACTATTTTTGACCTT |
| Streptococcus thermophilus CNRZ1066 | str0602 | -75 | 6.5 | ATAGATTTGACCTTTTTTGACCAA |
| Streptococcus uberis 0140J | SUB1281 | -61 | 6.7 | TAAAGTTTGACCATTTTTGACTAA |
|
Position: -107
Score: 6.9 Sequence: TTTTTCTTGACTATTTTTGACCAA
Locus tag: MGAS10750_Spy1856
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| MGAS10750_Spy1856 | -107 | 6.9 | TTTTTCTTGACTATTTTTGACCAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: groS | ||||
| Ortholog function: Heat shock protein 60 family co-chaperone GroES | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_0439 | -95 | 5.9 | TTTCTCTTGACTAAATCTGACCAT |
| Lactococcus lactis subsp. lactis Il1403 | L198515 | -96 | 5.9 | TTTCTCTTGACTAAATCTGACCAT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_2041 | -106 | 6.9 | TTTTTCTTGACTATTTTTGACCAA |
| Streptococcus gallolyticus UCN34 | GALLO_0124 | -134 | 6.8 | TTTTTCTTGACTATTTCTGACCAA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1886 | -96 | 6.9 | TTTTTCTTGACTATTTTTGACCAA |
| Streptococcus mitis B6 | smi_0481 | -102 | 6.8 | TTTTTCTTGACTATTTCTGACCAA |
| Streptococcus mutans UA159 | SMU.1955 | -91 | 6.9 | TTTTTCTTGACTATTTTTGACCAA |
| Streptococcus pneumoniae TIGR4 | SP_1907 | -102 | 6.2 | TTTTTCTTGATTATTTCTGACCAA |
| Streptococcus pyogenes M1 GAS | SPy2072 | -107 | 6.9 | TTTTTCTTGACTATTTTTGACCAA |
| Streptococcus sanguinis SK36 | SSA_0225 | -97 | 6.8 | TTTTTCTTGACTATTTCTGACCAA |
| Streptococcus suis 05ZYH33 | SSU05_0147 | -66 | 6.5 | ATGTTCTTGACTATTTTTGACCAA |
| Streptococcus uberis 0140J | SUB1742 | -108 | 6.6 | TTTTTCTTGACTAATTTTGACCAA |