Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of CmbR regulog to Streptococcus pyogenes MGAS10750

Reference regulog properties
Source regulog: CmbR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LysR
Regulation mode: repressor (activator)
Biological process: Cysteine metabolism
Effector: O-acetyl-L-serine
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes MGAS10750
Orthologous TF(s) MGAS10750_Spy0793, MGAS10750_Spy0725
Regulated genes 5
Built upon 104 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes MGAS10750
Locus tag Position Score Sequence
Position: -75
Score: 4.5
Sequence: TTGATAGGAATCAATTATTAG
Locus tag: MGAS10750_Spy0265
MGAS10750_Spy0265 -75 4.5 TTGATAGGAATCAATTATTAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: gshT
Ortholog function: Predicted glutathione ABC transporter, substrate-binding protein
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0381 -75 5 TTGATAGGAATTAATTATTAG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1680 -41 5 ATGATAAACTAATCTTATGAA
Streptococcus gallolyticus UCN34 GALLO_1845 -122 6 GTGATAAGTTTTATTTATCAC
Streptococcus mitis B6 smi_1945 -99 5.1 GCCATAAAGAAAACCTATCAC
Streptococcus mutans UA159 SMU.1942c -98 6 GTGATAGAATTTTCTTATCAC
-76 4.6 GTGATAGAAATTATATAATAG
Streptococcus pyogenes M1 GAS SPy0317 -75 4.5 TTGATAGGAATCAATTATTAG
Streptococcus thermophilus CNRZ1066 str0296 -98 5.7 GTGATAGTATTTTCTTATCAC
Streptococcus uberis 0140J SUB0365 -93 4.9 GTGATAGAGAACTATTATCAT
-71 4.2 GCGATAGTGAATCACTATTAG
Position: -10
Score: 4.7
Sequence: TTGATAAAATATGACTATGAA
Locus tag: MGAS10750_Spy1084
MGAS10750_Spy1084 -10 4.7 TTGATAAAATATGACTATGAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: dfpB
Ortholog function: Phosphopantothenoylcysteine synthetase (EC 6.3.2.5)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1040 -10 4.4 ATGATAAAATATGGCTATGAA
Streptococcus pyogenes M1 GAS SPy1221 -16 4.7 TTGATAAAATATGACTATGAA
Position: -115
Score: 5.2
Sequence: GTGATATGGATTTATTATCAG
Locus tag: MGAS10750_Spy1438
MGAS10750_Spy1438 -115 5.2 GTGATATGGATTTATTATCAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysK
Ortholog function: Cysteine synthase (EC 2.5.1.47)
Lactococcus lactis subsp. lactis Il1403 L0089 -79 5.3 GCTATAAAAAAATCTTATAGC
Lactococcus lactis subsp. lactis Il1403 L0088 -87 4.5 ATCATAAATTTTTTTTAGAGC
Streptococcus mitis B6 smi_2060 -98 5.3 GATATAAAAAAATCCTATCAC
Streptococcus thermophilus CNRZ1066 str0366 -16 5.2 ATGATAAAATTTTTTTATGGA
Streptococcus uberis 0140J SUB1379 -104 5.1 ATGATAAGCCTTTCCTATCAC
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