Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of CtsR regulog to Streptococcus pyogenes MGAS10270

Reference regulog properties
Source regulog: CtsR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: CtsR
Regulation mode: repressor
Biological process: Heat shock response
Effector: Heat shock
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes MGAS10270
Orthologous TF(s) MGAS10270_Spy1832
Regulated genes 3
Built upon 68 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes MGAS10270
Locus tag Position Score Sequence
Position: -172
Score: 6.3
Sequence: TTTTGTTTGACCTTTACTGACCTT
Locus tag: MGAS10270_Spy0752
MGAS10270_Spy0752 -172 6.3 TTTTGTTTGACCTTTACTGACCTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: clpL
Ortholog function: ATP-dependent Clp protease, ATP-binding subunit
Streptococcus agalactiae 2603V/R SAG1303 -144 6.3 TATTTATTGACCTTTACTGACTAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0851 -180 6.4 TTTTGTTTGACCTTAACTGACCAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1072 -181 6.3 TTTTGTTTGACCTTTACTGACCTT
Streptococcus gallolyticus UCN34 GALLO_1249 -190 6.6 AAATATTTGACTTTTACTGACCAA
Streptococcus mitis B6 smi_1765 -276 6.3 AAATCCTTGACCTTTTCTGACTAA
Streptococcus pneumoniae TIGR4 SP_0338 -275 6.5 AAACTCTTGACCTTTTCTGACCAA
Streptococcus pyogenes M1 GAS SPy0888 -172 6.3 TTTTGTTTGACCTTTACTGACCTT
Streptococcus suis 05ZYH33 SSU05_0389 -254 6.1 AAACTATTGACTTTTACTGACCAA
Streptococcus suis 05ZYH33 SSU05_0390 -254 6.1 AAACTATTGACTTTTACTGACCAA
Streptococcus suis 05ZYH33 SSU05_0391 -254 6.1 AAACTATTGACTTTTACTGACCAA
Streptococcus thermophilus CNRZ1066 str1614 -84 -0.1 TTGGTCAGTAAAAGTCAATTTTTA
Streptococcus uberis 0140J SUB0776 -152 6.9 TTTTTCTTGACCTTTTTTGACCAA
Position: -62
Score: 6.7
Sequence: TAAAGTTTGACCATTTTTGACTAA
Locus tag: MGAS10270_Spy1256
MGAS10270_Spy1256 -62 6.7 TAAAGTTTGACCATTTTTGACTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: clpE
Ortholog function: ATP-dependent Clp protease, ATP-binding subunit ClpE
Lactococcus lactis subsp. cremoris SK11 LACR_0578 -119 -0.4 ATGGTCAAATATGGTCAAGCTTTT
Lactococcus lactis subsp. lactis Il1403 L0221 -117 -0.9 ATGGTCAAATATGGTCAAACTTTT
Streptococcus agalactiae 2603V/R SAG0488 -65 6.3 TAAAGTTTGACTATATTTGACTAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1496 -62 6.7 TAAAGTTTGACCATTTTTGACTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0605 -63 6.7 TAAAGTTTGACCATTTTTGACTAA
Streptococcus gallolyticus UCN34 GALLO_0612 -65 5.7 TGAAGTTTGACTATCTTTGACCTT
Streptococcus gordonii str. Challis substr. CH1 SGO_0688 -65 6.9 TAAAGTTTGACTATTTTTGACCAA
Streptococcus mitis B6 smi_0865 -62 6.3 TAGAATTTGACTATTTTTGACCTT
Streptococcus mutans UA159 SMU.562 -74 6.6 TAAAGTTTGACCATTATTGACCAT
Streptococcus pneumoniae TIGR4 SP_0820 -62 6.3 TAGAATTTGACTATTTTTGACCTT
Streptococcus pyogenes M1 GAS SPy1509 -62 6.7 TAAAGTTTGACCATTTTTGACTAA
Streptococcus sanguinis SK36 SSA_0669 -73 6.2 AAAACTTTGACTATTTTTGACCTT
Streptococcus thermophilus CNRZ1066 str0602 -75 6.5 ATAGATTTGACCTTTTTTGACCAA
Streptococcus uberis 0140J SUB1281 -61 6.7 TAAAGTTTGACCATTTTTGACTAA
Position: -107
Score: 6.9
Sequence: TTTTTCTTGACTATTTTTGACCAA
Locus tag: MGAS10270_Spy1830
MGAS10270_Spy1830 -107 6.9 TTTTTCTTGACTATTTTTGACCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: groS
Ortholog function: Heat shock protein 60 family co-chaperone GroES
Lactococcus lactis subsp. cremoris SK11 LACR_0439 -95 5.9 TTTCTCTTGACTAAATCTGACCAT
Lactococcus lactis subsp. lactis Il1403 L198515 -96 5.9 TTTCTCTTGACTAAATCTGACCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2041 -106 6.9 TTTTTCTTGACTATTTTTGACCAA
Streptococcus gallolyticus UCN34 GALLO_0124 -134 6.8 TTTTTCTTGACTATTTCTGACCAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1886 -96 6.9 TTTTTCTTGACTATTTTTGACCAA
Streptococcus mitis B6 smi_0481 -102 6.8 TTTTTCTTGACTATTTCTGACCAA
Streptococcus mutans UA159 SMU.1955 -91 6.9 TTTTTCTTGACTATTTTTGACCAA
Streptococcus pneumoniae TIGR4 SP_1907 -102 6.2 TTTTTCTTGATTATTTCTGACCAA
Streptococcus pyogenes M1 GAS SPy2072 -107 6.9 TTTTTCTTGACTATTTTTGACCAA
Streptococcus sanguinis SK36 SSA_0225 -97 6.8 TTTTTCTTGACTATTTCTGACCAA
Streptococcus suis 05ZYH33 SSU05_0147 -66 6.5 ATGTTCTTGACTATTTTTGACCAA
Streptococcus uberis 0140J SUB1742 -108 6.6 TTTTTCTTGACTAATTTTGACCAA
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