Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of HrcA regulog to Streptococcus pyogenes MGAS10270

Reference regulog properties
Source regulog: HrcA - Streptococcaceae
Regulator type: Transcription factor
Regulator family: HrcA
Regulation mode: repressor
Biological process: Heat shock response
Effector: Heat shock
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes MGAS10270
Orthologous TF(s) MGAS10270_Spy1568
Regulated genes 2
Built upon 49 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes MGAS10270
Locus tag Position Score Sequence
Position: -132
Score: 7.9
Sequence: TTAGCACTCTTTATAAAAGAGTGCTAA
Position: -48
Score: 7.6
Sequence: TTAGCAGTCTACTAAATAGAGTGCTAA
Locus tag: MGAS10270_Spy1568
MGAS10270_Spy1568 -132 7.9 TTAGCACTCTTTATAAAAGAGTGCTAA
-48 7.6 TTAGCAGTCTACTAAATAGAGTGCTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: hrcA
Ortholog function: Heat shock response transcriptional regulator HrcA, HrcA family
Lactococcus lactis subsp. cremoris SK11 LACR_1025 -141 8.1 TTAGCACTCTAATAAAAAGAGTGCTAA
-61 7 TTAGCACTTAGAGGTAAAGAGTGCTAA
Lactococcus lactis subsp. lactis Il1403 L0212 -214 7.8 TTAGCACTCTACCAAAAAGAGTGCTAA
-134 6.7 TTAGCACTTAGAGATGAAGAGTGCTAA
Streptococcus agalactiae 2603V/R SAG0095 -140 7.9 TTAGCACTCTTTGAATAAGAGTGCTAA
-58 7.2 TTAGCAGTCGATGTGTAAGAGTGCTAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1830 -47 7.1 TTAGCAGTCAGATACATAGAGTGCTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0400 -48 6.9 TTAGCAGTCCGATGTATAGAGTGCTAA
Streptococcus gallolyticus UCN34 GALLO_0241 -130 8 TTAGCACTCTACTAAAAAGAGTGCTAA
-47 7.1 TTAGCAGTCGAGGTATATGAGTGCTAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0400 -142 7.9 TTAGCACTCTTGCAAAAAGAGTGCTAA
-59 6.3 TTAGCACTCAAAGTGGTCGAGTGCTAA
Streptococcus mitis B6 smi_0353 -136 7.5 TTAGCACTCTTGATGAAAGAGTGCTAA
-53 6.5 TTAGCACTTGAGTGCATCGAGTGCTAA
Streptococcus mutans UA159 SMU.80 -143 7.5 TTAGCACTCAAGCAGAAAGAGTGCTAA
-59 7.2 TTAGCAGTCGTCTGTTAAGAGTGCTAA
Streptococcus pneumoniae TIGR4 SP_0515 -136 7.8 TTAGCACTCTTGATAAAAGAGTGCTAA
-53 6.5 TTAGCACTTGGATGCATTGAGTGCTAA
Streptococcus pyogenes M1 GAS SPy1763 -132 7.4 TTAGCGCTCTTTATAAAAGAGTGCTAA
-48 7.6 TTAGCAGTCTACTAAATAGAGTGCTAA
Streptococcus sanguinis SK36 SSA_2009 -142 8 TTAGCACTCTTGTAAAAAGAGTGCTAA
-59 7 TTAGCACTCGAGGTGATTGAGTGCTAA
Streptococcus suis 05ZYH33 SSU05_0298 -226 7.8 TTAGCACTCTAAGCAAAAGAGTGCTAA
-140 7.4 TTAGCACTCGATATCATAGAGTGCTAA
Streptococcus thermophilus CNRZ1066 str0118 -137 8 TTAGCACTCTTTCAAAAAGAGTGCTAA
-49 7.2 TTAGCAGTCGTTGTACGAGAGTGCTAA
Streptococcus uberis 0140J SUB1506 -45 7.1 TTAGCAGTCTTAGCATCAGAGTGCTAA
Position: -62
Score: 7.5
Sequence: TTAGCACTCGATGAACATGAGTGCTAA
Locus tag: MGAS10270_Spy1830
MGAS10270_Spy1830 -62 7.5 TTAGCACTCGATGAACATGAGTGCTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: groS
Ortholog function: Heat shock protein 60 family co-chaperone GroES
Lactococcus lactis subsp. cremoris SK11 LACR_0439 -51 7.1 TTAGCACACAACTATTAAGAGTGCTAA
Lactococcus lactis subsp. lactis Il1403 L198515 -52 7.9 TTAGCACTCGTTTAATAAGAGTGCTAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2041 -61 7.7 TTAGCACTCGTACAACAAGAGTGCTAA
Streptococcus gallolyticus UCN34 GALLO_0124 -86 7.5 TTAGCACTCGATGTATTAGAGTGCTAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1886 -50 7.3 TTAGCACTCGATAGACGAGAGTGCTAA
Streptococcus mitis B6 smi_0481 -57 7.7 TTAGCACTCATCTATAAAGAGTGCTAA
Streptococcus mutans UA159 SMU.1955 -46 7 TTAGCACTCAGTATATTGGAGTGCTAA
Streptococcus pneumoniae TIGR4 SP_1907 -57 7.6 TTAGCACTCAAGTTCAAAGAGTGCTAA
Streptococcus pyogenes M1 GAS SPy2072 -62 7.1 TTAGCCCTCGATGAACATGAGTGCTAA
Streptococcus sanguinis SK36 SSA_0225 -51 7.3 TTAGCACTCGATAGTTTAGAGTGCTAA
Streptococcus suis 05ZYH33 SSU05_0147 -20 7.7 TTAGCACTCGAATACAAAGAGTGCTAA
Streptococcus uberis 0140J SUB1742 -63 7.5 TTGGCACTCTTTTTTAAAGAGTGCTAA
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