Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of CmbR regulog to Streptococcus suis 98HAH33

Reference regulog properties
Source regulog: CmbR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LysR
Regulation mode: repressor (activator)
Biological process: Cysteine metabolism
Effector: O-acetyl-L-serine
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus suis 98HAH33
Orthologous TF(s) SSU98_0783, SSU98_1023, SSU98_1024
Regulated genes 5
Built upon 104 sites [see more]
Predicted regulatory interactions in Streptococcus suis 98HAH33
Locus tag Position Score Sequence
Position: -27
Score: 4.5
Sequence: GAGATAGTTTTTTTATATTAT
Locus tag: SSU98_0422
SSU98_0422 -27 4.5 GAGATAGTTTTTTTATATTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysK
Ortholog function: Cysteine synthase (EC 2.5.1.47)
Lactococcus lactis subsp. lactis Il1403 L0089 -79 5.3 GCTATAAAAAAATCTTATAGC
Lactococcus lactis subsp. lactis Il1403 L0088 -87 4.5 ATCATAAATTTTTTTTAGAGC
Streptococcus mitis B6 smi_2060 -98 5.3 GATATAAAAAAATCCTATCAC
Streptococcus thermophilus CNRZ1066 str0366 -16 5.2 ATGATAAAATTTTTTTATGGA
Streptococcus uberis 0140J SUB1379 -104 5.1 ATGATAAGCCTTTCCTATCAC
Position: -46
Score: 4.7
Sequence: GTTATAGCCAAAACTTATAAC
Locus tag: SSU98_1322
SSU98_1322 -46 4.7 GTTATAGCCAAAACTTATAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: metA
Ortholog function: Homoserine O-succinyltransferase (EC 2.3.1.46)
Lactococcus lactis subsp. lactis Il1403 L0101 -132 4.3 GCCATAGGCAAGTTTTATTAT
Streptococcus gallolyticus UCN34 GALLO_0824 -107 4.3 ATTATAGCTAAAAACTATAAC
Streptococcus pneumoniae TIGR4 SP_1576 -145 4.6 GATATAAAAATAGACTATAAC
Streptococcus suis 05ZYH33 SSU05_1306 -46 4.7 GTTATAGCCAAAACTTATAAC
Position: -120
Score: 5.1
Sequence: GTTATAAAGAAAAACTATAAC
Locus tag: SSU98_1571
SSU98_1571 -120 5.1 GTTATAAAGAAAAACTATAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: metB1
Ortholog function: Cystathionine gamma-synthase (EC 2.5.1.48)
Lactococcus lactis subsp. lactis Il1403 L0102 -132 4.3 GCCATAGGCAAGTTTTATTAT
Streptococcus gallolyticus UCN34 GALLO_1768 -142 5 GTTATAGTTTTTACTTATAGC
Streptococcus mutans UA159 SMU.1675 -110 4.3 CTTATAGTTTCTTTTTATAGC
Streptococcus suis 05ZYH33 SSU05_1562 -120 5.1 GTTATAAAGAAAAACTATAAC
Streptococcus thermophilus CNRZ1066 str0352 -132 4.5 GTTATAGTAATAAACTATATC
Position: -95
Score: 5.3
Sequence: CTGATAGTTATTTTTTATCAA
Locus tag: SSU98_1783
SSU98_1783 -95 5.3 CTGATAGTTATTTTTTATCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: yvdE
Ortholog function: Predicted glutamine amidotransferase, class I
Streptococcus gallolyticus UCN34 GALLO_1848 -98 5.2 GTGATAAAAAAAATCTATTGG
-61 5 AGGATAGAATAATCTTATCAC
Streptococcus gordonii str. Challis substr. CH1 SGO_0167 -97 5.5 TTGATAAAAAATTTTTATAAG
Streptococcus pneumoniae TIGR4 SP_2072 -64 5.2 TCCATAAAAAATGTTTATCAC
Streptococcus sanguinis SK36 SSA_2164 -100 5.8 CTGATAAAAAATTTTTATAAC
Streptococcus suis 05ZYH33 SSU05_1773 -95 5.3 CTGATAGTTATTTTTTATCAA
Position: -338
Score: 4.3
Sequence: TTCATAGATAAAATCTATACC
Position: -245
Score: 4.1
Sequence: TTTATATAGAAGAAATATCAA
Position: -202
Score: 4.5
Sequence: GTTATAGTCAAAAGTTATAAC
Locus tag: SSU98_1784
SSU98_1784 -338 4.3 TTCATAGATAAAATCTATACC
-245 4.1 TTTATATAGAAGAAATATCAA
-202 4.5 GTTATAGTCAAAAGTTATAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Lactococcus lactis subsp. cremoris SK11 LACR_1368 -39 4.7 TTGATAAGATAGACCTATTAA
Lactococcus lactis subsp. lactis Il1403 L0100 -76 4.1 ATCATATTAAAAATGTATTAT
-39 4.7 TTGATAAGATAGACCTATTAA
Streptococcus agalactiae 2603V/R SAG2049 -109 4.1 GCTAAAAATATAAAATATTAA
Streptococcus gallolyticus UCN34 GALLO_1316 -221 4.2 ATAATAAATTTTATTAATCTA
-172 4.6 GTTATAGTTAAAAACTATAAT
Streptococcus gordonii str. Challis substr. CH1 SGO_0310 -182 4.2 GTTATAGTTTTTGATTATACC
Streptococcus mutans UA159 SMU.873 -188 4.6 GTTATAGATGAAAACTATAAC
Streptococcus pneumoniae TIGR4 SP_0585 -218 4.9 CTTATAAGAATTACTAATAAC
Streptococcus sanguinis SK36 SSA_0416 -182 4.3 GTCATAATTTCTACCTATAGC
Streptococcus suis 05ZYH33 SSU05_1774 -237 4.3 TTCATAGATAAAATCTATACC
Streptococcus thermophilus CNRZ1066 str0785 -119 4.2 GCTATACAAATATCTAATTAA
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