Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of NiaR regulog to Streptococcus pyogenes MGAS6180

Reference regulog properties
Source regulog: NiaR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: NiaR
Regulation mode: repressor
Biological process: NAD biosynthesis
Effector: Niacin
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes MGAS6180
Orthologous TF(s) M28_Spy1157
Regulated genes 3
Built upon 23 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes MGAS6180
Locus tag Position Score Sequence
Position: -95
Score: 6.2
Sequence: TACAATTGTCTTGACACTTGTT
Locus tag: M28_Spy0168
M28_Spy0168 -95 6.2 TACAATTGTCTTGACACTTGTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nadC
Ortholog function: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
Streptococcus gallolyticus UCN34 GALLO_1935 -177 4.7 GCCAGGTGTCAAGACACCTGTA
Streptococcus pneumoniae TIGR4 SP_2016 -134 6 TACAATTGTCTTGACAATTGTC
-122 5.7 GACAATTGTCTTGACACTTGTT
Streptococcus pyogenes M1 GAS SPy0197 -122 6.2 TACAATTGTCTTGACACTTGTT
Position: -59
Score: 5.6
Sequence: TACAGGTGTCTTGATAGTTATT
Locus tag: M28_Spy1156
M28_Spy1156 -59 5.6 TACAGGTGTCTTGATAGTTATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: niaX
Ortholog function: Substrate-specific component NiaX of predicted niacin ECF transporter
Streptococcus agalactiae 2603V/R SAG1602 -58 6.4 TACAGGTGTCTTTACACCTGTA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1467 -59 6.1 TATAGGTGTCTTGACACTTGTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0638 -62 4.2 GCTAGGTGTCTTGACATCTGTC
Streptococcus gallolyticus UCN34 GALLO_0647 -191 5.8 TACAGGTGTCTTGACACCTGTG
Streptococcus gordonii str. Challis substr. CH1 SGO_1046 -32 6.2 TACTACTGTATATACACATAAA
Streptococcus mitis B6 smi_1196 -33 6.5 TACTAGTGTATATACAGTTAAA
Streptococcus mutans UA159 SMU.332 -67 6.3 AACTAGTGTCTTGACAGATGTA
Streptococcus pneumoniae TIGR4 SP_1233 20 6.2 TACTAGTGTATATGCAGTTAAA
Streptococcus pyogenes M1 GAS SPy1425 -59 5.6 TACAGGTGTCTTGATAGTTATT
Streptococcus sanguinis SK36 SSA_1348 -33 6.5 TACTAGTGTATATACAGATAAA
Streptococcus suis 05ZYH33 SSU05_2019 -173 5.8 TACAGGCGTCTTGACACCTGTA
Streptococcus thermophilus CNRZ1066 str0890 28 6.1 TACTATTGTATTTACAGAAAAA
Streptococcus uberis 0140J SUB1261 -58 6.3 TACAGGTGTCTTGACACCTGTA
Position: -85
Score: 4.7
Sequence: AATAGATGTCTTGATACCTGTA
Locus tag: M28_Spy1500
M28_Spy1500 -85 4.7 AATAGATGTCTTGATACCTGTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pncA
Ortholog function: Nicotinamidase (EC 3.5.1.19)
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1847 -88 4.8 GTTAGTTGTCTTGACACCTGTA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0388 -139 5.1 ATCTACTGTCTTGACAGCTGTC
Streptococcus pyogenes M1 GAS SPy1776 -88 4.7 AATAGATGTCTTGATACCTGTA
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