Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of Rex regulog to Streptococcus agalactiae COH1

Reference regulog properties
Source regulog: Rex - Streptococcaceae
Regulator type: Transcription factor
Regulator family: Rex
Regulation mode: repressor
Biological process: Energy metabolism
Effector: NADH
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus agalactiae COH1
Orthologous TF(s) SAN_1220
Regulated genes 10
Built upon 161 sites [see more]
Predicted regulatory interactions in Streptococcus agalactiae COH1
Locus tag Position Score Sequence
Position: -48
Score: 3.8
Sequence: TTTTTAATATTTAATCAA
Position: -32
Score: 4.5
Sequence: AAGTTAATAAAATCACAT
Locus tag: SAN_1201
SAN_1201 -48 3.8 TTTTTAATATTTAATCAA
-32 4.5 AAGTTAATAAAATCACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nirC
Ortholog function: Formate/nitrite family of transporters
Streptococcus agalactiae 2603V/R SAG1084 -32 4.5 AAGTTAATAAAATCACAT
Streptococcus gordonii str. Challis substr. CH1 SGO_1137 -40 3.8 ATGATATATTGGTCATAA
Streptococcus mitis B6 smi_1009 -41 4.3 TTGTGATATAATTATCAG
Streptococcus pneumoniae TIGR4 SP_1215 -41 5 TTGTGATATAATTATCAA
Streptococcus sanguinis SK36 SSA_1098 -44 4.5 TTGTGATATACTATACAT
Position: -36
Score: 4.5
Sequence: TAATAAAATTTTTAACAA
Locus tag: SAN_1220
SAN_1220 -36 4.5 TAATAAAATTTTTAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: rex
Ortholog function: Redox-sensitive transcriptional regulator Rex, Rex family
Lactococcus lactis subsp. cremoris SK11 LACR_1156 -74 5.3 TTGATAAAATTATCACAA
Lactococcus lactis subsp. lactis Il1403 L71932 -75 5.3 TTGATAAAATTATCACAA
Streptococcus agalactiae 2603V/R SAG1100 -36 4.5 TAATAAAATTTTTAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1050 -31 4.4 TAGTTGCATATTTCACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1228 -54 4.7 TAGTTGATTTTTTCACAA
Streptococcus mitis B6 smi_1188 -57 5 TTGTTGATTTTTTCACAA
Streptococcus mutans UA159 SMU.1053 -117 4.4 TTGTTATAAAAAAAACTA
-58 4.5 ATGTTGCATTTTTCACAA
Streptococcus pneumoniae TIGR4 SP_1090 -57 5 TTGTTGATTTTTTCACAA
Streptococcus pyogenes M1 GAS SPy1120 -76 4.5 ATGTTGCATTTTTCACAA
Streptococcus sanguinis SK36 SSA_1216 -55 4.7 TAGTTGATTTTTTCACAA
Streptococcus suis 05ZYH33 SSU05_1069 -100 4.5 CTGTTGATTTTTTCACAA
Streptococcus thermophilus CNRZ1066 str1463 -39 4.6 TTGTTGCAATCTTCACAA
Streptococcus uberis 0140J SUB0845 -52 4.4 TTGTTACAATAGTAACAT
Position: -72
Score: 4
Sequence: TCGTGAAACTTTTAATTA
Position: -30
Score: 3.9
Sequence: TAGTAAATAAAAAAAGAA
Locus tag: SAN_0855
SAN_0855 -72 4 TCGTGAAACTTTTAATTA
-30 3.9 TAGTAAATAAAAAAAGAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: tpi
Ortholog function: Triosephosphate isomerase (EC 5.3.1.1)
Streptococcus agalactiae 2603V/R SAG0763 -72 4 TCGTGAAACTTTTAATTA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0629 -97 5.1 TTGTGAAAATATTCCTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1321 -97 5 TTGTGAAAATATTACTAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0762 -89 4.5 TTGATAAAAACTTAGCAA
Streptococcus pyogenes M1 GAS SPy0613 -97 5.1 TTGTGAAAATATTCCTAA
Streptococcus thermophilus CNRZ1066 str0488 -46 4.7 TTGTGATAAAATAAACGA
Streptococcus uberis 0140J SUB0605 -98 5.2 TTGTGAAAATTATCCCAA
Position: -60
Score: 4.2
Sequence: TTGTGCTAGAATTAACAT
Locus tag: SAN_0158
SAN_0158 -60 4.2 TTGTGCTAGAATTAACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: fba
Ortholog function: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)
Streptococcus gallolyticus UCN34 GALLO_0255 -60 4.2 TTGTGATAAAATGTACGT
Streptococcus gordonii str. Challis substr. CH1 SGO_1745 -61 4.6 AAGTGATAAAATAAACAA
Streptococcus mutans UA159 SMU.99 -61 4.6 AAGTGATAAAATAAACAA
Streptococcus pneumoniae TIGR4 SP_0605 -62 4.5 AAGTGATAAAATGAACAA
Streptococcus sanguinis SK36 SSA_1992 -62 4.6 AAGTGATAAAATAAACAA
Position: -166
Score: 4.3
Sequence: TTGTGAATTTGTGAAAAA
Position: -59
Score: 4.7
Sequence: TTGTGAATAATGTTATAA
Locus tag: SAN_1044
SAN_1044 -166 4.3 TTGTGAATTTGTGAAAAA
-59 4.7 TTGTGAATAATGTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: noxE
Ortholog function: NADH oxidase (EC 1.6.99.3)
Streptococcus agalactiae 2603V/R SAG0958 -165 4.3 TTGTGAATTTGTGAAAAA
-59 4.7 TTGTGAATAATGTTATAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0909 -23 4.6 TTGTGAAATGAGGAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1023 -81 4.3 TTGTGAAATGAGGAACAT
Streptococcus pyogenes M1 GAS SPy1150 -23 4.6 TTGTGAAATGAGGAACAA
Streptococcus thermophilus CNRZ1066 str1281 -91 4.6 TTGTTCAAAAAGTAACAA
Streptococcus uberis 0140J SUB0877 -170 4.6 TTGTGAATTTATGAACTA
-24 4.7 TTGTGAAAAGAGGAACAA
Position: -113
Score: 5.2
Sequence: TTGAAAAAAAGTTCACAA
Position: -90
Score: 5.5
Sequence: TTGTGAAACTATTTACAA
Position: -35
Score: 5.6
Sequence: TTGTGAAACATTTAACAA
Locus tag: SAN_0074
SAN_0074 -113 5.2 TTGAAAAAAAGTTCACAA
-90 5.5 TTGTGAAACTATTTACAA
-35 5.6 TTGTGAAACATTTAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhE
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)
Streptococcus agalactiae 2603V/R SAG0053 -113 5.2 TTGAAAAAAAGTTCACAA
-90 5.5 TTGTGAAACTATTTACAA
-35 5.6 TTGTGAAACATTTAACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0061 -112 5.2 TTGAAAAAAACTTCACAA
-89 5.4 TTGTGAAATGATTTACAA
-34 5.5 TTGTGAAACTTTTAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0043 -112 5 TTGAAAAAAACATCACAA
-89 5.4 TTGTGAAATGATTTACAA
-34 5.5 TTGTGAAACTTTTAACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0113 -140 5.1 TTGAAATATATTTCACAA
-51 5.8 TTGTGAAAAAATTAACAA
Streptococcus mitis B6 smi_0231 -209 4.5 TTGTGAAATAAAAAATAT
-191 5.1 TTGAAATAATTTTCACAA
-141 5.4 ATGAGAAAAATTTCACAA
-97 4.6 TTATGAAACTGTTTACAA
-53 5.8 TTGTGAAAAAATTAACAA
Streptococcus pneumoniae TIGR4 SP_2026 -208 4.5 TTGTGAAATAAAAAATAT
-190 5.1 TTGAAATAAATTTCACAA
-140 5.1 ATGAGAAAAGTTTCACAA
-96 4.6 TTATGAAACTGTTTACAA
-52 5.8 TTGTGAAAAAATTAACAA
Streptococcus sanguinis SK36 SSA_0068 -226 4.3 ATGTGAAATCTTTAAAAT
-156 5 TTGTTATGTATTTCACAA
-67 5.7 TTGTGAAATATTTAACAA
Streptococcus suis 05ZYH33 SSU05_0280 -129 4.5 TTGGGGAAAAGTTAACAA
Streptococcus uberis 0140J SUB0063 -116 5.2 TTGAAAAAAAGTTCACAA
-93 5.5 TTGTGAAACTATTTACAA
-38 5.5 TTGTGAAACTTTTAACAA
Position: -76
Score: 4.4
Sequence: AAGTTAATCTTTTCACAT
Locus tag: SAN_1899
SAN_1899 -76 4.4 AAGTTAATCTTTTCACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: gap
Ortholog function: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
Streptococcus agalactiae 2603V/R SAG1768 -76 4.4 AAGTTAATCTTTTCACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1936 -78 4.7 AAGTTAATCTTTTCACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0207 -158 4 ATTTGAAAGAATGAACAA
Streptococcus mutans UA159 SMU.360 -81 4.7 AAGTTAATCTTTTCACAA
Streptococcus pyogenes M1 GAS SPy0274 -79 4.7 AAGTTAATCTTTTCACAA
Streptococcus sanguinis SK36 SSA_2108 -157 4.8 TAGTGAAAGAATTCATAA
Streptococcus thermophilus CNRZ1066 str1788 -50 4.7 AAGTTAATCTTTTCACAA
Streptococcus uberis 0140J SUB1630 -78 4.7 AAGTTAATCTTTTCACAA
Position: -84
Score: 4.7
Sequence: TTGTGAAAAAGTAATCAA
Locus tag: SAN_1897
SAN_1897 -84 4.7 TTGTGAAAAAGTAATCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pgk
Ortholog function: Phosphoglycerate kinase (EC 2.7.2.3)
Lactococcus lactis subsp. cremoris SK11 LACR_0248 -91 4.5 TTGTGATATAATTAACCT
Lactococcus lactis subsp. lactis Il1403 L0010 -91 4.5 TTGTGATATAATTAACCT
Streptococcus agalactiae 2603V/R SAG1766 -84 4.7 TTGTGAAAAAGTAATCAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0272 -96 4.3 TTGTGAAATAGTTAATTT
Streptococcus gallolyticus UCN34 GALLO_1995 -137 4.4 TTGTAAAATGATACAGAA
-47 4.5 TTGTGATATAATTAGCAT
Streptococcus gordonii str. Challis substr. CH1 SGO_0209 -46 4.7 TTGTGATATAATTATCAT
Streptococcus mutans UA159 SMU.361 -47 4.7 TTGTGATATAATTATCAT
Streptococcus sanguinis SK36 SSA_0302 -87 4.5 TTGTGAAAATTTTCTTTA
Streptococcus suis 05ZYH33 SSU05_0157 -87 4.4 TTGTGAAAAAAATATCTT
Streptococcus uberis 0140J SUB1629 -96 4.5 TTGTGAAAAAAATAATTT
Position: -59
Score: 4.7
Sequence: TTGTGAATAATGTTATAA
Locus tag: SAN_1046
SAN_1046 -59 4.7 TTGTGAATAATGTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: noxE
Ortholog function: NADH oxidase (EC 1.6.99.3)
Streptococcus agalactiae 2603V/R SAG0958 -165 4.3 TTGTGAATTTGTGAAAAA
-59 4.7 TTGTGAATAATGTTATAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0909 -23 4.6 TTGTGAAATGAGGAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1023 -81 4.3 TTGTGAAATGAGGAACAT
Streptococcus pyogenes M1 GAS SPy1150 -23 4.6 TTGTGAAATGAGGAACAA
Streptococcus thermophilus CNRZ1066 str1281 -91 4.6 TTGTTCAAAAAGTAACAA
Streptococcus uberis 0140J SUB0877 -170 4.6 TTGTGAATTTATGAACTA
-24 4.7 TTGTGAAAAGAGGAACAA