Propagation of PurR regulog to Streptococcus suis SC84
| Source regulog: | PurR - Streptococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | PurR |
| Regulation mode: | repressor |
| Biological process: | Purine metabolism |
| Effector: | 5-phosphoribosyl 1-pyrophosphate |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Streptococcus suis SC84 |
| Orthologous TF(s) | SSUSC84_1802 |
| Regulated genes | 8 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -16
Score: 4.8 Sequence: AAAGGCGAACATT
Locus tag: SSUSC84_0025
|
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| SSUSC84_0025 | -16 | 4.8 | AAAGGCGAACATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: purC | ||||
| Ortholog function: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1622 | -132 | 4.8 | ATTTCCGAACATT |
| -115 | 5.1 | AAAACCGAACAAT | ||
| Lactococcus lactis subsp. lactis Il1403 | L177350 | -132 | 4.8 | ATTTCCGAACATT |
| -115 | 5.1 | AAAACCGAACAAT | ||
| Streptococcus agalactiae 2603V/R | SAG0024 | -108 | 4.9 | AAATACGAACGTT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0043 | -106 | 5.2 | AAAAACGAACATT |
| -13 | 4.2 | AAAGACGAATATT | ||
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0023 | -110 | 5.2 | AAAAACGAACATT |
| -16 | 4.3 | AAAGGCGAACAAA | ||
| Streptococcus gallolyticus UCN34 | GALLO_0025 | -109 | 4.3 | AATTTCGAACGTT |
| -16 | 4.3 | AAAGGCGAACAAA | ||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0034 | -16 | 4.8 | AAAGGCGAACATT |
| Streptococcus mitis B6 | smi_0066 | 155 | 4.3 | AAAGGCGAACTTT |
| Streptococcus mutans UA159 | SMU.29 | -109 | 4.8 | AAATGCGAACGAT |
| -16 | 4.7 | AAAGGCGAACAAT | ||
| Streptococcus pneumoniae TIGR4 | SP_0044 | -16 | 4.3 | AAAGGCGAACTTT |
| Streptococcus pyogenes M1 GAS | SPy0024 | -78 | 4.7 | AAAAACGAACCTT |
| Streptococcus sanguinis SK36 | SSA_0028 | -16 | 4.1 | AAAGGCGAATATT |
| Streptococcus suis 05ZYH33 | SSU05_0026 | -16 | 4.8 | AAAGGCGAACATT |
| Streptococcus thermophilus CNRZ1066 | str0030 | -109 | 4.9 | AAATCCGAACGTT |
| -16 | 4.6 | AAAGGCGAACGAT | ||
| Streptococcus uberis 0140J | SUB0025 | -108 | 5.2 | AAAAACGAACATT |
| -15 | 4.7 | AAAGGCGAACAAT | ||
|
Position: -88
Score: 4.5 Sequence: ATTCCCGAACATT
Locus tag: SSUSC84_0031
|
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| SSUSC84_0031 | -88 | 4.5 | ATTCCCGAACATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: purD | ||||
| Ortholog function: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1601 | -266 | 4.9 | AATTCCGAACAAT |
| Lactococcus lactis subsp. lactis Il1403 | L153005 | -224 | 5 | AATACCGAACAAT |
| Streptococcus agalactiae 2603V/R | SAG0043 | -88 | 4.5 | AAAAGCGAACAAA |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0051 | -108 | 4.9 | ATTAACGAACATT |
| -57 | 4.5 | ATAAACGAACAAA | ||
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0030 | -14 | 5 | ATAAACGAACAAT |
| Streptococcus gallolyticus UCN34 | GALLO_0032 | -116 | 4.3 | ATTTCCGAACAAA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_2092 | -121 | 4.5 | TAAAACGAACGAT |
| Streptococcus mitis B6 | smi_0073 | -56 | 4.6 | TAAAACGAACGTT |
| Streptococcus mutans UA159 | SMU.48 | -122 | 3.5 | ACTCCCGAACAAA |
| Streptococcus pneumoniae TIGR4 | SP_0051 | -56 | 4.2 | TAAAACGAACTTT |
| Streptococcus pyogenes M1 GAS | SPy0032 | -55 | 4.9 | AAAAGCGAACGTT |
| Streptococcus sanguinis SK36 | SSA_0037 | -121 | 4.5 | TAAAACGAACGAT |
| Streptococcus suis 05ZYH33 | SSU05_0033 | -88 | 4.5 | ATTCCCGAACATT |
| Streptococcus thermophilus CNRZ1066 | str0040 | -121 | 3.8 | ATCTCCGAACAAA |
| Streptococcus uberis 0140J | SUB0053 | -57 | 4 | ATTCACGAACAAA |
|
Position: -4
Score: 3.5 Sequence: AAGCATGAACATT
Locus tag: SSUSC84_0032
|
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| SSUSC84_0032 | -4 | 3.5 | AAGCATGAACATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: purE | ||||
| Ortholog function: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1599 | -266 | 4.9 | AATTCCGAACAAT |
| Lactococcus lactis subsp. lactis Il1403 | L152487 | -224 | 5 | AATACCGAACAAT |
| Streptococcus agalactiae 2603V/R | SAG0044 | -88 | 4.5 | AAAAGCGAACAAA |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0031 | -14 | 5 | ATAAACGAACAAT |
| Streptococcus gallolyticus UCN34 | GALLO_0034 | -116 | 4.3 | ATTTCCGAACAAA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_2090 | -121 | 4.5 | TAAAACGAACGAT |
| Streptococcus mitis B6 | smi_0074 | -56 | 4.6 | TAAAACGAACGTT |
| Streptococcus mutans UA159 | SMU.50 | -122 | 3.5 | ACTCCCGAACAAA |
| Streptococcus pneumoniae TIGR4 | SP_0053 | -56 | 4.2 | TAAAACGAACTTT |
| Streptococcus pyogenes M1 GAS | SPy0033 | -55 | 4.9 | AAAAGCGAACGTT |
| Streptococcus sanguinis SK36 | SSA_0039 | -121 | 4.5 | TAAAACGAACGAT |
| Streptococcus suis 05ZYH33 | SSU05_0034 | -88 | 4.5 | ATTCCCGAACATT |
| Streptococcus thermophilus CNRZ1066 | str0041 | -121 | 3.8 | ATCTCCGAACAAA |
| Streptococcus uberis 0140J | SUB0054 | -57 | 4 | ATTCACGAACAAA |
|
Position: -97
Score: 4.1 Sequence: AATTCCGTACGTT
Locus tag: SSUSC84_0615
|
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| SSUSC84_0615 | -97 | 4.1 | AATTCCGTACGTT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: fhs | ||||
| Ortholog function: Formate--tetrahydrofolate ligase (EC 6.3.4.3) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1007 | -134 | 4.8 | ATTTCCGAACAAT |
| Lactococcus lactis subsp. lactis Il1403 | L159505 | -131 | 4.8 | ATTTCCGAACAAT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1033 | -93 | 5.2 | AAAAACGAACATT |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0945 | -94 | 4.9 | AAAAGCGAACGTT |
| Streptococcus gallolyticus UCN34 | GALLO_1115 | -100 | 4.8 | AAACACGAACATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1210 | -95 | 4.8 | AAACACGAACAAT |
| Streptococcus mitis B6 | smi_1192 | -90 | 4.2 | TTTTACGAACGTT |
| Streptococcus mutans UA159 | SMU.1073 | -90 | 5.1 | AAATCCGAACATT |
| Streptococcus pneumoniae TIGR4 | SP_1229 | -172 | 4.6 | AAAAACGAAGATT |
| -89 | 4.7 | ATTTACGAACGTT | ||
| Streptococcus pyogenes M1 GAS | SPy1213 | -93 | 5.1 | AAAAACGAACAAT |
| Streptococcus sanguinis SK36 | SSA_1200 | -93 | 4.1 | TTTCCCGAACATT |
| Streptococcus suis 05ZYH33 | SSU05_0690 | -97 | 4.1 | AATTCCGTACGTT |
| Streptococcus thermophilus CNRZ1066 | str0791 | -94 | 5.2 | AAAACCGAACATT |
|
Position: -231
Score: 4.3 Sequence: AATTCTGAACATT
Position: -139
Score: 4.2 Sequence: ATATCCGAATATT
Position: -98
Score: 4.1 Sequence: AAACACAAACAAT
Locus tag: SSUSC84_0724
|
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| SSUSC84_0724 | -231 | 4.3 | AATTCTGAACATT | |
| -139 | 4.2 | ATATCCGAATATT | ||
| -98 | 4.1 | AAACACAAACAAT | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: guaC | ||||
| Ortholog function: GMP reductase (EC 1.7.1.7) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1256 | -232 | 4.7 | ATTTCCGAACGTT |
| Lactococcus lactis subsp. lactis Il1403 | L158186 | -227 | 3.9 | ATTTCCGAATGAT |
| Streptococcus agalactiae 2603V/R | SAG1087 | -149 | 5.2 | AAAAACGAACATT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0894 | -205 | 5.2 | AAAACCGAACATT |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1036 | -209 | 5 | AAAAACGAACGTT |
| Streptococcus gallolyticus UCN34 | GALLO_1025 | -260 | 5.2 | AAAAACGAACATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1159 | -146 | 4.7 | ATTTCCGAACGTT |
| Streptococcus mitis B6 | smi_1212 | -141 | 4.9 | AAATCCGAACGAT |
| Streptococcus pneumoniae TIGR4 | SP_1249 | -141 | 4.6 | AAACCCGAACGAT |
| Streptococcus pyogenes M1 GAS | SPy1135 | -205 | 4.7 | AAAACCGAACTTT |
| Streptococcus suis 05ZYH33 | SSU05_0815 | -87 | 4.3 | AATTCTGAACATT |
| Streptococcus uberis 0140J | SUB0865 | -187 | 4.6 | AAATCCGAACAAA |
|
Position: -82
Score: 3.8 Sequence: AAAGACGGACTTT
Locus tag: SSUSC84_1802
|
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| SSUSC84_1802 | -82 | 3.8 | AAAGACGGACTTT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: purR | ||||
| Ortholog function: Purine metabolism transcriptional regulator PurR, PurR family | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_2590 | 6 | 4.4 | AGAAACGAACGTT |
| Lactococcus lactis subsp. lactis Il1403 | L134453 | 6 | 4.4 | AGAAACGAACGTT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1941 | -85 | 4.6 | AAAAACGGACATT |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0264 | -109 | 5.2 | AAAAACGAACATT |
| Streptococcus gallolyticus UCN34 | GALLO_2000 | -87 | 3.9 | AAAAATGGACATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0202 | -85 | 4.6 | AAAAACGAGCATT |
| Streptococcus sanguinis SK36 | SSA_2114 | -56 | 3.9 | AAAAATGGACATT |
| Streptococcus uberis 0140J | SUB1636 | -88 | 4.2 | AAAGATGAACAAT |