Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of NrdR regulog to Streptococcus pyogenes M1 GAS

Reference regulog properties
Source regulog: NrdR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: NrdR
Regulation mode: repressor
Biological process: Deoxyribonucleotide biosynthesis
Effector: Deoxyribonucleotides
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes M1 GAS
Orthologous TF(s) SPy0338
Regulated genes 3
Built upon 63 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes M1 GAS
Locus tag Position Score Sequence
Position: -291
Score: 5.7
Sequence: ACACTATATCTTGTGT
Locus tag: SPy0425
SPy0425 -291 5.7 ACACTATATCTTGTGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nrdF1
Ortholog function: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
Streptococcus agalactiae 2603V/R SAG0418 -274 5.2 ACACAAGATATAGTGG
-242 4.3 ACACAAAACTTTGTGT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0474 -306 4.1 CTACTATATATTGTCA
-275 4.9 GCACTATATCTTGTGG
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_0524 -306 5.2 AATCTATATATTGTAT
-274 5.5 GCACTATATATTGTGT
Streptococcus pyogenes M1 GAS SPy0425 -323 4.4 AAACTATATCTTGTCA
-291 5.7 ACACTATATCTTGTGT
Position: -117
Score: 5.7
Sequence: ACACAATATGTTGTGT
Locus tag: SPy1374
SPy1374 -117 5.7 ACACAATATGTTGTGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ndrH
Ortholog function: Glutaredoxin-like protein NrdH
Streptococcus pyogenes M1 GAS SPy1374 -149 4.6 ACACAATATTTAGGTT
-117 5.7 ACACAATATGTTGTGT
Position: -91
Score: 5.2
Sequence: TATCAATATATTGTGT
Position: -59
Score: 5.8
Sequence: ACACAATATATTGATT
Locus tag: SPy2110
SPy2110 -91 5.2 TATCAATATATTGTGT
-59 5.8 ACACAATATATTGATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nrdD
Ortholog function: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Lactococcus lactis subsp. cremoris SK11 LACR_0277 -99 5.9 ACACAAGATATTGTGT
-68 5.2 ATTCTATATATTGTGT
Lactococcus lactis subsp. lactis Il1403 L70400 -99 5.9 ACACAAGATATTGTGT
-68 5 AACCTATATATTGTGT
Streptococcus agalactiae 2603V/R SAG2086 -118 5.7 AATCAATATATTGTGT
-86 5.8 ACACAATATATTGATT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_2078 -90 5.4 AATCAATATCTTGTGT
-58 5.8 ACACAATATATTGATT
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1861 -91 5.7 AATCAATATATTGTGT
-59 5.8 ACACAATATATTGATT
Streptococcus gallolyticus UCN34 GALLO_2185 -94 4.9 ACGCAATATCTTGTGG
-62 5.3 CCACAAGATATTGATT
Streptococcus gordonii str. Challis substr. CH1 SGO_2033 -106 5 TATCAATATCTTGTGT
-65 5.6 ACACAAGATATTGATT
Streptococcus mitis B6 smi_1912 -110 5.4 AATCAATATCTTGTGT
-69 5.3 CCACAAGATATTGATT
Streptococcus mutans UA159 SMU.2074 -92 5.2 TATCAATATATTGTGT
-61 5.5 CCACAATATATTGATT
Streptococcus pneumoniae TIGR4 SP_0202 -116 5.4 AATCAATATCTTGTGT
-75 5.6 ACACAAGATATTGATT
Streptococcus pyogenes M1 GAS SPy2110 -91 5.2 TATCAATATATTGTGT
-59 5.8 ACACAATATATTGATT
Streptococcus sanguinis SK36 SSA_2230 -217 5.3 AATCAATATGTTGTGT
-176 5 CCACAACATATTGATT
Streptococcus suis 05ZYH33 SSU05_2118 -56 5.6 ACACAAGATATTGATT
Streptococcus thermophilus CNRZ1066 str1963 -103 5 AATCAATATATAGTGG
-71 5.5 CCACAATATATTGATT
Streptococcus uberis 0140J SUB1772 -94 5.7 AATCAATATATTGTGT
-62 5.6 ACACAAGATATTGATT
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