Propagation of LexA regulog to Lactobacillus plantarum WCFS1
| Source regulog: | LexA - Lactobacillaceae |
| Regulator type: | Transcription factor |
| Regulator family: | LexA |
| Regulation mode: | repressor |
| Biological process: | SOS response |
| Effector: | DNA damage |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Lactobacillus plantarum WCFS1 |
| Orthologous TF(s) | lp_2063 |
| Regulated genes | 9 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -52
Score: 4.6 Sequence: ACGAACAGATGTTTTA
Locus tag: lp_0308
|
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| lp_0308 | -52 | 4.6 | ACGAACAGATGTTTTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: srmB | ||||
| Ortholog function: DinG family ATP-dependent helicase | ||||
| Lactobacillus brevis ATCC 367 | LVIS_1870 | -70 | 4.1 | TCGAACACGCGTTCAA |
| Lactobacillus casei ATCC 334 | LSEI_0288 | -55 | 4.5 | GAGAATGTATGTTCTA |
| Lactobacillus plantarum WCFS1 | lp_0308 | -52 | 4.6 | ACGAACAGATGTTTTA |
| Lactobacillus rhamnosus GG | LGG_00328 | -55 | 4.3 | CAGAATGTATGTTCTA |
|
Position: -146
Score: 5 Sequence: GCGAAAGTATGTTCGA
Locus tag: lp_0772
|
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| lp_0772 | -146 | 5 | GCGAAAGTATGTTCGA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: uvrB | ||||
| Ortholog function: Excinuclease ABC, subunit B | ||||
| Lactobacillus acidophilus NCFM | LBA0688 | -87 | 4.6 | GCGAAAACACGTTCGT |
| Lactobacillus brevis ATCC 367 | LVIS_0648 | -101 | 4.9 | GCGAAAGTATGTTCGG |
| Lactobacillus casei ATCC 334 | LSEI_0956 | -206 | 5 | GCGAAAGTATGTTCGC |
| -127 | 4.2 | ACGAAATTTTGTTTGG | ||
| Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 | LBUL_0549 | -64 | 4.1 | TAGAATCTATGTTCGG |
| Lactobacillus fermentum IFO 3956 | LAF_0353 | -99 | 4.7 | ACGAATAAACGTTCGT |
| Lactobacillus helveticus DPC 4571 | lhv_0729 | -86 | 4.6 | GCGAAAACACGTTCGT |
| Lactobacillus johnsonii NCC 533 | LJ0863 | -86 | 5 | GCGAAAATACGTTCGC |
| Lactobacillus plantarum WCFS1 | lp_0772 | -146 | 5 | GCGAAAGTATGTTCGA |
| Lactobacillus reuteri JCM 1112 | LAR_0372 | -132 | 4.4 | ACGAATACATGTTTGG |
| Lactobacillus rhamnosus GG | LGG_00923 | -271 | 5 | GCGAAAGTATGTTCGC |
| Lactobacillus sakei subsp. sakei 23K | LSA0523 | -190 | 4.9 | GCGAAAATACGTTCGG |
| Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 | LEUM_0392 | -89 | 4.9 | TAGAACGTTTGTTCGT |
| Oenococcus oeni PSU-1 | OEOE_0372 | -50 | 4.2 | GGGAACTAATGTTCGC |
| Pediococcus pentosaceus ATCC 25745 | PEPE_0448 | -127 | 4.9 | GCGAAAGTATGTTCGG |
|
Position: -185
Score: 4.9 Sequence: GCGAACGTGTGTTTGC
Locus tag: lp_1840
|
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| lp_1840 | -185 | 4.9 | GCGAACGTGTGTTTGC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: parE | ||||
| Ortholog function: Topoisomerase IV subunit B (EC 5.99.1.-) | ||||
| Lactobacillus brevis ATCC 367 | LVIS_0804 | -70 | 4.7 | TTGAACATACGTTCGG |
| Lactobacillus plantarum WCFS1 | lp_1840 | -185 | 4.9 | GCGAACGTGTGTTTGC |
| Lactobacillus reuteri JCM 1112 | LAR_0752 | -45 | 4.6 | TCGAACATACGTTTAG |
| Lactobacillus rhamnosus GG | LGG_01419 | -179 | 4.5 | ACGAACACACATTCGA |
| Lactobacillus sakei subsp. sakei 23K | LSA0976 | -113 | 4.7 | GCGAACATACATTTGG |
| Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 | LEUM_1364 | -36 | 4.3 | ACGAACACTGGTTCGT |
| Oenococcus oeni PSU-1 | OEOE_1026 | -8 | 4.8 | ACGAATGAATGTTCGC |
|
Position: -191
Score: 4.3 Sequence: TAGAACAACTGTTTGG
Locus tag: lp_1899
|
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| lp_1899 | -191 | 4.3 | TAGAACAACTGTTTGG | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: dnaE | ||||
| Ortholog function: DNA polymerase III alpha subunit (EC 2.7.7.7) | ||||
| Lactobacillus brevis ATCC 367 | LVIS_0763 | -86 | 4.7 | ACGAACATTTGTTCAT |
| Lactobacillus plantarum WCFS1 | lp_1899 | -191 | 4.3 | TAGAACAACTGTTTGG |
| Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 | LEUM_0774 | -29 | 4.5 | GAAAACGGATGTTCGT |
| Oenococcus oeni PSU-1 | OEOE_1000 | -45 | 5 | GCGAACATACTTTCGT |
|
Position: -81
Score: 5 Sequence: CCGAACATTTGTTTGA
Locus tag: lp_2063
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| lp_2063 | -81 | 5 | CCGAACATTTGTTTGA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: lexA | ||||
| Ortholog function: SOS-response regulator and protease LexA, LexA family (EC 3.4.21.88) | ||||
| Lactobacillus acidophilus NCFM | LBA1280 | -80 | 4.1 | AAGAACGCCTGTTTGA |
| Lactobacillus casei ATCC 334 | LSEI_1968 | -53 | 4.1 | TCAAAAGTTTTTTTGT |
| Lactobacillus casei ATCC 334 | LSEI_0730 | -61 | 5 | GCAAACGTTCGTTCGC |
| Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 | LBUL_1265 | -85 | 4.1 | TAGAACGCCCGTTTGC |
| Lactobacillus fermentum IFO 3956 | LAF_0708 | -79 | 4.9 | TCGAACGTACGTTTTA |
| Lactobacillus helveticus DPC 4571 | lhv_1364 | -82 | 4.8 | TAGAACATTCGTTTGA |
| Lactobacillus johnsonii NCC 533 | LJ1508 | -71 | 4.1 | AAGAACGCCTGTTTGC |
| Lactobacillus plantarum WCFS1 | lp_2063 | -81 | 5 | CCGAACATTTGTTTGA |
| Lactobacillus reuteri JCM 1112 | LAR_0650 | -71 | 5.2 | GCGAACGTACGTTTGA |
| Lactobacillus rhamnosus GG | LGG_00717 | -60 | 4.7 | GCAAACGTCCGTTCGT |
| Lactobacillus sakei subsp. sakei 23K | LSA1275 | -70 | 4.7 | ACGAACACTTGTTTGA |
| Lactobacillus salivarius subsp. salivarius UCC118 | LSL_0540 | -74 | 4.6 | ACGAACGTTAGTTTGA |
| Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 | LEUM_1204 | -75 | 5 | ACGAACAAACGTTTGA |
| Oenococcus oeni PSU-1 | OEOE_0970 | -76 | 4.9 | ACGAACATGTGTTTGT |
| Pediococcus pentosaceus ATCC 25745 | PEPE_0870 | -68 | 5.1 | GCGAACATTTGTTTGA |
|
Position: -85
Score: 4.8 Sequence: TTGAACGTATGTTCGT
Locus tag: lp_2280
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| lp_2280 | -85 | 4.8 | TTGAACGTATGTTCGT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: dinP | ||||
| Ortholog function: DNA polymerase IV (EC 2.7.7.7) | ||||
| Lactobacillus brevis ATCC 367 | LVIS_1226 | -49 | 4.2 | GCAAACGCCCGTTCGG |
| Lactobacillus plantarum WCFS1 | lp_2280 | -85 | 4.8 | TTGAACGTATGTTCGT |
| Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 | LEUM_1586 | -32 | 3.9 | AAGAACACTTGTTCCT |
|
Position: -90
Score: 4.8 Sequence: ACGAACTTTTGTTCGC
Locus tag: lp_2301
|
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| lp_2301 | -90 | 4.8 | ACGAACTTTTGTTCGC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: recA | ||||
| Ortholog function: DNA recombinase A | ||||
| Lactobacillus acidophilus NCFM | LBA0666 | -82 | 4.2 | TTGAACATTAGTTTGT |
| Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 | LBUL_0535 | -84 | 4.1 | TTGAACGTTAGTTCGG |
| Lactobacillus fermentum IFO 3956 | LAF_0511 | -89 | 3.9 | CCGAACCCCTGTTCGA |
| Lactobacillus helveticus DPC 4571 | lhv_0713 | -82 | 4.1 | TTGAACGTTAGTTTGT |
| Lactobacillus plantarum WCFS1 | lp_2301 | -90 | 4.8 | ACGAACTTTTGTTCGC |
| Lactobacillus reuteri JCM 1112 | LAR_0509 | -89 | 4.3 | ACGAACTTTTGTTCAC |
| Lactobacillus sakei subsp. sakei 23K | LSA0487 | -94 | 4.9 | AAGAACGTTTGTTCGA |
| Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 | LEUM_0584 | -82 | 5.2 | ACGAACAAATGTTCGA |
| Oenococcus oeni PSU-1 | OEOE_1382 | -57 | 5.2 | ACGAACAAATGTTCGT |
| Pediococcus pentosaceus ATCC 25745 | PEPE_1276 | -84 | 4.8 | TCGAACTTTTGTTCGC |
|
Position: -32
Score: 4.3 Sequence: GAGAACGTTTGTTCAG
Locus tag: lp_2694
|
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| lp_2694 | -32 | 4.3 | GAGAACGTTTGTTCAG | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: addB | ||||
| Ortholog function: ATP-dependent nuclease, subunit B | ||||
| Lactobacillus acidophilus NCFM | LBA1166 | -8 | 4.1 | GCGAACAAATGATCAA |
| Lactobacillus brevis ATCC 367 | LVIS_2268 | -202 | 4.4 | TTGAACGTGTGTTCGT |
| Lactobacillus fermentum IFO 3956 | LAF_0036 | -75 | 4.1 | GCGAACATTCATTCCC |
| Lactobacillus helveticus DPC 4571 | lhv_1274 | -8 | 4.1 | GCGAACAAATGATCAA |
| Lactobacillus plantarum WCFS1 | lp_2694 | -32 | 4.3 | GAGAACGTTTGTTCAG |
| Lactobacillus reuteri JCM 1112 | LAR_0047 | -67 | 4.8 | AAGAATATATGTTCGT |
| Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 | LEUM_1482 | -62 | 4.3 | ACGAACAATCGTGCGC |
|
Position: -192
Score: 4.9 Sequence: AAGAACATATGTTCTT
Locus tag: lp_3023
|
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| lp_3023 | -192 | 4.9 | AAGAACATATGTTCTT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: umuC | ||||
| Ortholog function: UV-damage repair protein | ||||
| Lactobacillus fermentum IFO 3956 | LAF_1605 | -67 | 3.9 | CCGAACACTTGTTCCG |
| Lactobacillus plantarum WCFS1 | lp_3023 | -192 | 4.9 | AAGAACATATGTTCTT |
| Lactobacillus reuteri JCM 1112 | LAR_1238 | -59 | 4.8 | TTGAACATATGTTTGA |