Propagation of CcpA regulog to Lactobacillus helveticus DPC 4571

Reference regulog properties
Source regulog:	CcpA - Lactobacillaceae
Regulator type:	Transcription factor
Regulator family:	LacI
Regulation mode:
Biological process:	Carbon catabolism
Effector:	HPr, phosphocarrier protein; Fructose-1,6-bisphosphate
Phylum:	Firmicutes
Propagated regulon:
Target genome	Lactobacillus helveticus DPC 4571
Orthologous TF(s)	lhv_0457
Regulated genes	19

Built upon 561 sites [see more]

Predicted regulatory interactions in *Lactobacillus helveticus DPC 4571*
	Locus tag	Position	Score	Sequence
Position: -130 Score: 4.7 Sequence: GTAAAAGCGCTTACAT Locus tag: lhv_0152
	lhv_0152	-130	4.7	GTAAAAGCGCTTACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: LBA0143
Ortholog function: Maltodextrin glucosidase (EC 3.2.1.20); Alpha-glucosidase, family 31 of glycosyl hydrolase
Lactobacillus casei ATCC 334	LSEI_2769	-90	4.8	TTGAATGCGGTTACAA
Lactobacillus helveticus DPC 4571	lhv_0152	-130	4.7	GTAAAAGCGCTTACAT
Lactobacillus rhamnosus GG	LGG_02762	-77	4.8	ATGAATGCGGTTACAA

Position: -86 Score: 4.6 Sequence: GTGCAAACGTTTACAT Locus tag: lhv_0456
	lhv_0456	-86	4.6	GTGCAAACGTTTACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pepQ
Ortholog function: Xaa-Pro dipeptidase (EC 3.4.13.9)
Lactobacillus acidophilus NCFM	LBA0430	-85	4.6	TTGCAAACGTTTACAG
Lactobacillus brevis ATCC 367	LVIS_1204	-103	4.9	TTGAAAACGTTTTCGA
Lactobacillus casei ATCC 334	LSEI_0808	-229	4.2	ATGCAAGCGTTTTACT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	LBUL_1474	-89	4	GTGCAATCGCTTACAG
Lactobacillus helveticus DPC 4571	lhv_0456	-86	4.6	GTGCAAACGTTTACAT
Lactobacillus johnsonii NCC 533	LJ0490	-85	4.2	TTGCAACCGTTTACGA
Lactobacillus plantarum WCFS1	lp_2258	-158	5.2	TTGAAATCGCTTTCAT
Lactobacillus sakei subsp. sakei 23K	LSA0414	-120	4.1	ATGCAAGCGGTTTACA
Lactobacillus salivarius subsp. salivarius UCC118	LSL_0419	-125	4	TTGCAAGCGTTTCATA
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	LEUM_0543	-124	4.9	TTGCAAACGCTTACAA
		-102	4.2	TTATAAGTGTTTTCAT
Pediococcus pentosaceus ATCC 25745	PEPE_1251	-109	4.6	ATGAATACGTTATCAA

Position: -76 Score: 4.3 Sequence: ATGTAAACGTTTGCAC Locus tag: lhv_0457
	lhv_0457	-76	4.3	ATGTAAACGTTTGCAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: ccpA
Ortholog function: Carbon catabolism global transcriptional regulator CcpA, LacI family
Lactobacillus acidophilus NCFM	LBA0431	-75	4.4	CTGTAAACGTTTGCAA
Lactobacillus brevis ATCC 367	LVIS_1203	-107	4.7	TCGAAAACGTTTTCAA
		-49	4.1	TTGAAAACGGATGAAA
Lactobacillus casei ATCC 334	LSEI_0809	-94	4	AGTAAAACGCTTGCAT
Lactobacillus helveticus DPC 4571	lhv_0457	-76	4.3	ATGTAAACGTTTGCAC
Lactobacillus johnsonii NCC 533	LJ0491	-74	4	TCGTAAACGGTTGCAA
Lactobacillus plantarum WCFS1	lp_2256	-121	5.2	ATGAAAGCGATTTCAA
		-51	4	ATGAAAACGGATGAAA
Lactobacillus rhamnosus GG	LGG_00793	-95	4	AGTAAAACGCTTGCAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	LEUM_0544	-114	4.4	ATGAAAACACTTATAA
		-92	4.9	TTGTAAGCGTTTGCAA
Oenococcus oeni PSU-1	OEOE_0684	-59	4.6	ATGTAATCGCTTGCAT
Pediococcus pentosaceus ATCC 25745	PEPE_1250	-69	4.6	TTGATAACGTATTCAT

Position: -42 Score: 4.5 Sequence: ATAAAAGCGGATTCAT Locus tag: lhv_0480
	lhv_0480	-42	4.5	ATAAAAGCGGATTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: manL
Ortholog function: Mannose-specific PTS system, IIAB component (EC 2.7.1.69)
Lactobacillus acidophilus NCFM	LBA0452	-42	4.5	ATAAAAGCGGATTCAT
Lactobacillus fermentum IFO 3956	LAF_0391	-140	4.7	TAGTAAGCGTTTACAG
Lactobacillus helveticus DPC 4571	lhv_0480	-42	4.5	ATAAAAGCGGATTCAT
Lactobacillus johnsonii NCC 533	LJ0503	-106	4.4	ATGCAAGCATTTTCAA
		-68	4.1	AAGCAAACGTATACAT
Lactobacillus plantarum WCFS1	lp_0575	1	4	TGGTAAGCATTATCAT
Lactobacillus sakei subsp. sakei 23K	LSA0449	-136	4.2	AGTAAAGCGTTTTAAA
		-57	4.6	TTGTTAGCGTTTTTAT
Lactobacillus salivarius subsp. salivarius UCC118	LSL_0086	-109	4.3	TAGAAATCGTTTACAC
Lactobacillus salivarius subsp. salivarius UCC118	LSL_0654	-131	4.3	TAGTAAGTGTTTTCAA
		-61	4.1	ATGAAAAGGCTTTATT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	LEUM_1768	-100	4.7	ATGTAAACGGTAACAA
		-75	5.4	TTGAAAGCGTTTACAA
Pediococcus pentosaceus ATCC 25745	PEPE_1518	-146	4.5	TTGAAAGCGTTTTTTG

Position: -109 Score: 4.4 Sequence: ATGTAAGCTATTACAT Locus tag: lhv_0686
	lhv_0686	-109	4.4	ATGTAAGCTATTACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ptsH
Ortholog function: Phosphotransferase system, HPr-related protein
Lactobacillus acidophilus NCFM	LBA0639	-111	4.4	ATGTAAACTGTTACAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	LBUL_0512	-108	4.7	ATGAAAACATTTACAA
Lactobacillus helveticus DPC 4571	lhv_0686	-109	4.4	ATGTAAGCTATTACAT
Lactobacillus johnsonii NCC 533	LJ0816	-109	4.6	ATGTAAACATTTACAT
Lactobacillus plantarum WCFS1	lp_1273	-135	4	ATGAAAGGGCTTGTAT
Lactobacillus reuteri JCM 1112	LAR_1256	-102	4	TATTTAACGCTTACAA
Lactobacillus salivarius subsp. salivarius UCC118	LSL_0388	-91	4.1	TTGTTATCGTTTGCAT
		-68	4.2	ATGTAAACGTGTTCTT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	LEUM_1780	-157	5.3	ATGTAAACGTTTTCAT
		-63	4.7	TTGTAAGCGCTTTGAT
Pediococcus pentosaceus ATCC 25745	PEPE_0609	-127	4	ATGTAAGGGCTTGCTT

Position: -58 Score: 4.3 Sequence: AAGAAAAGGGTTTCAT Locus tag: lhv_0789
	lhv_0789	-58	4.3	AAGAAAAGGGTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pmi
Ortholog function: Mannose-6-phosphate isomerase (EC 5.3.1.8)
Lactobacillus acidophilus NCFM	LBA0745	-58	4.3	AAGAAAAGGGTTTCAT
Lactobacillus brevis ATCC 367	LVIS_1656	-86	4.8	TAGAAAGCGCTTGCAA
Lactobacillus helveticus DPC 4571	lhv_0789	-58	4.3	AAGAAAAGGGTTTCAT
Lactobacillus johnsonii NCC 533	LJ0916	-60	4.6	TTGAAAGTGGTTTCAA
Lactobacillus sakei subsp. sakei 23K	LSA1146	-99	4.1	ACGAAATCGCTTTAAA
Oenococcus oeni PSU-1	OEOE_0249	-30	4.9	ATGATAACGCTTACAT
Pediococcus pentosaceus ATCC 25745	PEPE_1334	-21	4.3	ATGAAAGGGGTTTTAT

Position: -14 Score: 4 Sequence: TAGGAAGCGGATTTAT Locus tag: lhv_0795
	lhv_0795	-14	4	TAGGAAGCGGATTTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pgi
Ortholog function: Glucose-6-phosphate isomerase (EC 5.3.1.9)
Lactobacillus acidophilus NCFM	LBA0752	-90	4.3	GTGAATGCGCTTATAA
Lactobacillus casei ATCC 334	LSEI_1126	-62	4	ATGAAACCACTCTCAT
Lactobacillus fermentum IFO 3956	LAF_1686	-63	4.4	GAGTTAGCGCTTTCAT
Lactobacillus fermentum IFO 3956	LAF_0411	-66	4.2	ATGGAAACGTTATCGT
Lactobacillus helveticus DPC 4571	lhv_0795	-14	4	TAGGAAGCGGATTTAT
Lactobacillus plantarum WCFS1	lp_2502	-77	3.8	GAGGAAGCGCTTTTCA
Lactobacillus reuteri JCM 1112	LAR_0415	-69	4.4	TTGAAACCGACTTCAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	LEUM_0355	-37	5	TTGTAACCGATTTCAT
Oenococcus oeni PSU-1	OEOE_0636	-118	3.9	TTGGAAGCTATTCCAA

Position: -236 Score: 5.2 Sequence: TTGTAAGCGATTTCAA Position: -149 Score: 4.7 Sequence: TAGGAACCGCTTTCAT Locus tag: lhv_0924
	lhv_0924	-236	5.2	TTGTAAGCGATTTCAA
		-149	4.7	TAGGAACCGCTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: lhv_0924
Ortholog function: Predicted transcriptional regulator, GntR family
Lactobacillus helveticus DPC 4571	lhv_0924	-236	5.2	TTGTAAGCGATTTCAA
		-149	4.7	TAGGAACCGCTTTCAT
Lactobacillus plantarum WCFS1	lp_0152	-193	4.2	ATGTAGCCGGTTACAT
Lactobacillus rhamnosus GG	LGG_02679	-170	4.7	TTAAATGCGCTTTCAT
Oenococcus oeni PSU-1	OEOE_1211	-167	4.4	ATGAAATCGCTACCAT
		-115	4	ATGTAAACTCTTTTTT
Pediococcus pentosaceus ATCC 25745	PEPE_1777	-141	4.7	TTGAATTCGCTTTCAT

Position: -34 Score: 4 Sequence: CTGAAAGCACTTACAG Locus tag: lhv_0941
	lhv_0941	-34	4	CTGAAAGCACTTACAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: bglB
Ortholog function: Beta-glucosidase (EC 3.2.1.21); 6-phospho-beta-glucosidase (EC 3.2.1.86)
Lactobacillus acidophilus NCFM	LBA0885	-35	4.8	ATGAAAGCGATTACAG
Lactobacillus helveticus DPC 4571	lhv_0941	-34	4	CTGAAAGCACTTACAG
Lactobacillus johnsonii NCC 533	LJ0194	-28	4.7	ATGTAAGCGATTGCAA
Lactobacillus plantarum WCFS1	lp_3011	-43	4.5	AGGAAAGCGTTTTCCA
Oenococcus oeni PSU-1	OEOE_1210	-93	4.5	ATGGTAGCGATTTCAT
Pediococcus pentosaceus ATCC 25745	PEPE_1776	-34	4.8	ATGAAAGCGAATTCAA

Position: -136 Score: 4.2 Sequence: ATGTAAGTGCTAACAT Locus tag: lhv_1049
	lhv_1049	-136	4.2	ATGTAAGTGCTAACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pfk
Ortholog function: 6-phosphofructokinase (EC 2.7.1.11)
Lactobacillus acidophilus NCFM	LBA0956	-134	4.2	ATGTAAGTGCTAACAT
Lactobacillus helveticus DPC 4571	lhv_1049	-136	4.2	ATGTAAGTGCTAACAT
Lactobacillus johnsonii NCC 533	LJ1079	-132	4.5	TTGAAAGCGAAAACAT
Pediococcus pentosaceus ATCC 25745	PEPE_1093	-116	4	AATAAAGCACTTACAT

Position: -35 Score: 4.6 Sequence: ATGAAAACGAATACAA Locus tag: lhv_1499
	lhv_1499	-35	4.6	ATGAAAACGAATACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: galM
Ortholog function: Aldose 1-epimerase (EC 5.1.3.3)
Lactobacillus acidophilus NCFM	LBA1457	-36	4.3	CTGAAAACGATTACAG
Lactobacillus casei ATCC 334	LSEI_0668	-65	4.7	ATAAAAACGGTTACAA
Lactobacillus helveticus DPC 4571	lhv_1499	-37	4.8	TTGAAAACGATTACAG
Lactobacillus johnsonii NCC 533	LJ0861	-36	5.1	ATGAAAACGATTACAA
Lactobacillus rhamnosus GG	LGG_00657	-64	4.7	ATAAAAACGGTTACAA

Position: -37 Score: 4.8 Sequence: TTGAAAACGATTACAG Locus tag: lhv_1501
	lhv_1501	-37	4.8	TTGAAAACGATTACAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: galK
Ortholog function: Galactokinase (EC 2.7.1.6)
Lactobacillus acidophilus NCFM	LBA1459	-36	4.3	CTGAAAACGATTACAG
Lactobacillus brevis ATCC 367	LVIS_1904	-98	4.7	ATGAAAACGTTTTATA
Lactobacillus fermentum IFO 3956	LAF_1792	-99	4.1	ATGTAAGCGCTCTATT
Lactobacillus helveticus DPC 4571	lhv_1501	-37	4.8	TTGAAAACGATTACAG
Lactobacillus johnsonii NCC 533	LJ0859	-36	5.1	ATGAAAACGATTACAA
Lactobacillus reuteri JCM 1112	LAR_1662	-125	4.5	GTGTAATCGTTTTCTT
		-93	4.4	TTGTAAGCGCTTATTG

Position: -41 Score: 4.6 Sequence: GTGTAAGCGATTTCTA Locus tag: lhv_1543
	lhv_1543	-41	4.6	GTGTAAGCGATTTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: lacS
Ortholog function: Lactose and galactose permease, GPH translocator family
Lactobacillus fermentum IFO 3956	LAF_0779	-92	4.2	TCGTAATCGGTTTCAT
Lactobacillus helveticus DPC 4571	lhv_1543	-41	4.6	GTGTAAGCGATTTCTA
Lactobacillus plantarum WCFS1	lp_3468	-177	4.2	AATAATACGCTTTCAT
		-66	4.6	ATGAAAGCGCTTATCA
Lactobacillus reuteri JCM 1112	LAR_1033	-42	4.7	TTGTAAGCGATTACAG
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	LEUM_1065	-80	4.5	CTGTAAGCGCTTCCAT

Position: -46 Score: 4.4 Sequence: ATAAAAGCTCTTTCAA Locus tag: lhv_1549
	lhv_1549	-46	4.4	ATAAAAGCTCTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: lacL
Ortholog function: Beta-galactosidase large subunit (EC 3.2.1.23)
Lactobacillus acidophilus NCFM	LBA1467	-47	5	ATAAAAGCGTTTTCAA
Lactobacillus brevis ATCC 367	LVIS_2259	-32	4.5	GTGTAAGCGTTTTATA
Lactobacillus fermentum IFO 3956	LAF_0247	-48	5	TTGAAACCGTTATCAT
Lactobacillus helveticus DPC 4571	lhv_1549	-46	4.4	ATAAAAGCTCTTTCAA
Lactobacillus johnsonii NCC 533	LJ0855	-45	4.4	ATAAAAGCGTCTTCAA
Lactobacillus plantarum WCFS1	lp_3483	-43	5	TTGTAAGCGTTTTTAT
Lactobacillus reuteri JCM 1112	LAR_0276	-53	4.4	ATGAAAGCGCTATACT
Lactobacillus sakei subsp. sakei 23K	LSA1711	-37	4.9	ATGAAACCGTTTTAAT
Lactobacillus salivarius subsp. salivarius UCC118	LSL_0376	-32	4.5	ATGTAAGCATTTTCTT
Pediococcus pentosaceus ATCC 25745	PEPE_0205	-41	4.8	TTGTAAGCGTTTTATA

Position: 12 Score: 4.3 Sequence: GAGAAAGCGGATACAA Locus tag: lhv_1846
	lhv_1846	12	4.3	GAGAAAGCGGATACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: fruR
Ortholog function: Fructose utilization transcriptional regulator FruR, DeoR family
Lactobacillus acidophilus NCFM	LBA1779	-37	4.2	GAGAAAGCGAATACAA
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	LBUL_1889	-164	4	GAGAAAGCCTTTACAA
Lactobacillus helveticus DPC 4571	lhv_1846	12	4.3	GAGAAAGCGGATACAA
Lactobacillus johnsonii NCC 533	LJ0570	-40	4.1	CTGAAAGCGTTTATCA
Lactobacillus plantarum WCFS1	lp_2095	-6	4.3	TTGAAAGTGCTTACAG
Lactobacillus sakei subsp. sakei 23K	LSA1048	-130	4	ATGAAAACCTTTACAC
		-40	4.3	TTGTAAACGATGACAT
Pediococcus pentosaceus ATCC 25745	PEPE_1166	-6	4.3	ATGAAAGTGCTTACAG

Position: -76 Score: 4.4 Sequence: TGTAAACCGCTTTCAA Locus tag: lhv_2000
	lhv_2000	-76	4.4	TGTAAACCGCTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: mapA
Ortholog function: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
Lactobacillus acidophilus NCFM	LBA1870	-74	4.4	TGTAAACCGCTTTCAA
		-48	4.6	ATGAAAGCGTAAACAA
Lactobacillus casei ATCC 334	LSEI_0982	-127	4.5	ATGATAGCGGTAACAT
Lactobacillus helveticus DPC 4571	lhv_2000	-76	4.4	TGTAAACCGCTTTCAA
Lactobacillus johnsonii NCC 533	LJ0213	-70	4.5	TGTTAAGCGCTTTCAA

Position: -61 Score: 4.3 Sequence: TTGATACCGGTAACAT Position: -34 Score: 4.3 Sequence: TTGAAAACGGTTTCCC Locus tag: lhv_2002
	lhv_2002	-61	4.3	TTGATACCGGTAACAT
		-34	4.3	TTGAAAACGGTTTCCC
Supported by regulated orthologs from reference regulons
Ortholog gene name: agl
Ortholog function: Oligo-1,6-glucosidase (EC 3.2.1.10)
Lactobacillus acidophilus NCFM	LBA1872	-49	5	TTGAAAACGGTTTCTT
Lactobacillus casei ATCC 334	LSEI_0980	-80	4.4	TTGATAACGGTAACAA
Lactobacillus helveticus DPC 4571	lhv_2002	-34	4.3	TTGAAAACGGTTTCCC
Lactobacillus johnsonii NCC 533	LJ0211	-53	5	TTGTAAGCGCTTATAA

Position: -178 Score: 4.5 Sequence: ATGAAAGCGCTATATT Locus tag: lhv_2003
	lhv_2003	-178	4.5	ATGAAAGCGCTATATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ackB
Ortholog function: Acetate kinase (EC 2.7.2.1)
Lactobacillus acidophilus NCFM	LBA1873	-72	4.4	ATGAAAGCGCTATACT
Lactobacillus helveticus DPC 4571	lhv_2003	-178	4.5	ATGAAAGCGCTATATT
Lactobacillus johnsonii NCC 533	LJ0485	-68	4.4	ATGAAAGCGCTATACT

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of CcpA regulog to Lactobacillus helveticus DPC 4571

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --