Propagation of FruR regulog to Yersinia pestis Nepal516

Reference regulog properties
Source regulog:	FruR - Enterobacteriales
Regulator type:	Transcription factor
Regulator family:	LacI
Regulation mode:	activator (repressor)
Biological process:	Central carbohydrate metabolism
Effector:	Fructose-1-phosphate; Fructose-1,6-diphosphate
Phylum:	Proteobacteria/gamma
Propagated regulon:
Target genome	Yersinia pestis Nepal516
Orthologous TF(s)	YPN_0410
Regulated genes	17

Built upon 213 sites [see more]

Predicted regulatory interactions in *Yersinia pestis Nepal516*
	Locus tag	Position	Score	Sequence
Position: -332 Score: 5.1 Sequence: GCTGAATCGATTTACC Locus tag: YPN_1389
	YPN_1389	-332	5.1	GCTGAATCGATTTACC
Supported by regulated orthologs from reference regulons
Ortholog gene name: ptsH
Ortholog function: PTS family, Hpr protein, phosphohistidinoprotein-hexose phosphotransferase
Escherichia coli str. K-12 substr. MG1655	b2415	-219	4.7	GCTGAATCGATTTTAT
Salmonella typhimurium LT2	STM2431	-219	4.7	GCTGAATCGATTTTAT
Citrobacter koseri ATCC BAA-895	CKO_00377	-219	5.1	GCTGAATCGATTTAAT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02762	-216	4.7	GCTGAATCGATTTTAT
Enterobacter sp. 638	Ent638_2943	-154	4.7	GCTGAATCGATTTTAT
Erwinia amylovora ATCC 49946	EAM_2391	-229	5.1	GCTGAATCGATTTACC
Yersinia pestis KIM	y1488	-332	5.1	GCTGAATCGATTTACC
Serratia proteamaculans 568	Spro_3448	-231	5	GCTGAATCGATTTACT
Edwardsiella tarda EIB202	ETAE_1132	-211	5.1	GCTGAATCGATTTAAC

Position: -128 Score: 4.6 Sequence: GCTGAAACGTTTTTAT Locus tag: YPN_1405
	YPN_1405	-128	4.6	GCTGAAACGTTTTTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: glk
Ortholog function: Glucokinase (EC 2.7.1.2)
Escherichia coli str. K-12 substr. MG1655	b2388	-134	4.9	GCTGAAACGATAAAGT
Salmonella typhimurium LT2	STM2403	-134	4	GCTGAAACAAGAAAGT
Citrobacter koseri ATCC BAA-895	CKO_00412	-134	4.9	GCTGAAACGATAAAGT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02738	-193	4.9	GCTGAAACGATAAAGT
Enterobacter sp. 638	Ent638_2921	-134	4.5	GCTGAAACGGTAAAGT
Yersinia pestis KIM	y1505	-125	4.6	GCTGAAACGTTTTTAT
Serratia proteamaculans 568	Spro_3407	-127	3.9	GCTGAAACGTTTTTTG

Position: -87 Score: 3.7 Sequence: ATTGACACGATTCCGC Locus tag: YPN_1623
	YPN_1623	-87	3.7	ATTGACACGATTCCGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: gapA
Ortholog function: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
Escherichia coli str. K-12 substr. MG1655	b1779	-87	3.7	ATTGACACGATTCCGC
Salmonella typhimurium LT2	STM1290	-87	3.7	ATTGACACGATTCCGC
Citrobacter koseri ATCC BAA-895	CKO_01800	-87	3.7	ATTGACACGATTCCGC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_01197	-87	3.7	ATTGACACGATTCCGC
Enterobacter sp. 638	Ent638_1675	-87	3.7	ATTGACACGATTCCGC
Erwinia amylovora ATCC 49946	EAM_1931	-78	3.7	ATTGACACGATTCCGC
Yersinia pestis KIM	y2165	-78	3.7	ATTGACACGATTCCGC
Serratia proteamaculans 568	Spro_2728	-87	3.7	ATTGACACGATTCCGC
Erwinia carotovora subsp. atroseptica SCRI1043	ECA2344	-93	3.7	ATTGACACGATTCCGC
Edwardsiella tarda EIB202	ETAE_1483	-87	3.7	ATTGACACGATTCCGC
Proteus mirabilis HI4320	PMI1504	-88	3.7	ATTGACACGATTCCGC
Photorhabdus luminescens subsp. laumondii TTO1	plu2558	-88	3.7	ATTGACACGATTCCGC

Position: -309 Score: 4.7 Sequence: GCTGAATGGTGTCAGC Locus tag: YPN_1646
	YPN_1646	-309	4.7	GCTGAATGGTGTCAGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: adhE
Ortholog function: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10)
Escherichia coli str. K-12 substr. MG1655	b1241	-264	4.6	GCTGAAAGGTGTCAGC
Salmonella typhimurium LT2	STM1749	-265	4.6	GCTGAAAGGTGTCAGC
Citrobacter koseri ATCC BAA-895	CKO_01318	-265	4.6	GCTGAAAGGTGTCAGC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02199	-260	4.5	GCTGAAAGGTATCAGC
Enterobacter sp. 638	Ent638_2304	-276	4.5	GCTGAAAGGTATCAGC
Erwinia amylovora ATCC 49946	EAM_1900	-246	4.6	GCTGAATGGTATCAGC
Yersinia pestis KIM	y2023	-309	4.7	GCTGAATGGTGTCAGC
Serratia proteamaculans 568	Spro_2704	-301	4.7	GCTGAATGGTGTCAGC
Erwinia carotovora subsp. atroseptica SCRI1043	ECA2326	-338	4.7	GCTGAATGGTGTCAGC
Edwardsiella tarda EIB202	ETAE_1508	-288	4.7	GCTGAATGGTGTCAGC
Proteus mirabilis HI4320	PMI1486	-269	4.6	GCTGAAAGGTGTCAGC
Photorhabdus luminescens subsp. laumondii TTO1	plu2496	-162	4.5	GCTGAAAGGAATCAGC

Position: -258 Score: 5.1 Sequence: GTTGAATGGTTTCAGC Locus tag: YPN_1847
	YPN_1847	-258	5.1	GTTGAATGGTTTCAGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: pykF
Ortholog function: Pyruvate kinase (EC 2.7.1.40)
Escherichia coli str. K-12 substr. MG1655	b1676	-221	4.9	CTTGAATGGTTTCAGC
Salmonella typhimurium LT2	STM1378	-221	4.9	CTTGAATGGTTTCAGC
Citrobacter koseri ATCC BAA-895	CKO_01709	-221	4.9	CTTGAATGGTTTCAGC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02133	-221	4.9	CTTGAATGGTTTCAGC
Enterobacter sp. 638	Ent638_1768	-221	5	GGTGAATGGTTTCAGC
Erwinia amylovora ATCC 49946	EAM_1657	-226	4.6	TTTGAATGGTTTCAGC
Yersinia pestis KIM	y1944	-258	5.1	GTTGAATGGTTTCAGC
Serratia proteamaculans 568	Spro_2187	-239	5.1	GTTGAATGGTTTCAGC
Erwinia carotovora subsp. atroseptica SCRI1043	ECA1867	-241	4.7	ATTGAATGGTTTCAGC
Edwardsiella tarda EIB202	ETAE_1850	-230	5.1	GTTGAATGGTTTCAGC
Proteus mirabilis HI4320	PMI1405	-269	5	GTTGAAAGGTTTCAGC
Photorhabdus luminescens subsp. laumondii TTO1	plu2613	-344	5.1	GTTGAATGGTTTCAGC

Position: -276 Score: 3.7 Sequence: GTTGAGTGGAATCAGT Position: -193 Score: 4.4 Sequence: GGTTGATCGATTCACC Locus tag: YPN_1863
	YPN_1863	-276	3.7	GTTGAGTGGAATCAGT
		-193	4.4	GGTTGATCGATTCACC
Supported by regulated orthologs from reference regulons
Ortholog gene name: ppsA
Ortholog function: Phosphoenolpyruvate synthase (EC 2.7.9.2)
Escherichia coli str. K-12 substr. MG1655	b1702	-102	4.6	GCTTGAACGATTCACC
Salmonella typhimurium LT2	STM1349	-103	4.6	GCTTGAACGATTCACC
Citrobacter koseri ATCC BAA-895	CKO_01725	-102	4.6	GCTTGAACGATTCACC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02160	-108	4.6	GCTTGAACGATTCACC
Enterobacter sp. 638	Ent638_1745	-103	4.4	GCTTACACGATTCACC
Erwinia amylovora ATCC 49946	EAM_1646	-104	3.7	GCCAGAGCGATTCAAC
Yersinia pestis KIM	y1930	-193	4.4	GGTTGATCGATTCACC
Serratia proteamaculans 568	Spro_2174	-132	4.4	GGTTGATCGATTCACC
Erwinia carotovora subsp. atroseptica SCRI1043	ECA1853	-117	4.4	GGTTGATCGATTCACC
Edwardsiella tarda EIB202	ETAE_1789	-113	4.4	GGTGTAACGATTCACC
Proteus mirabilis HI4320	PMI1421	-124	4.4	GGTTGATCGATTCACC
Photorhabdus luminescens subsp. laumondii TTO1	plu2628	-114	4.4	GGTTGATCGATTCACC

Position: 15 Score: 3.6 Sequence: CCTGAATTGATTGAGA Locus tag: YPN_2144
	YPN_2144	15	3.6	CCTGAATTGATTGAGA
Supported by regulated orthologs from reference regulons
Ortholog gene name: nuoH
Ortholog function: NADH dehydrogenase I chain H
Escherichia coli str. K-12 substr. MG1655	b2282	-283	3.6	ACGGACACGATTCAAC
Salmonella typhimurium LT2	STM2322	-283	3.6	ACGGACACGATTCAAC
Citrobacter koseri ATCC BAA-895	CKO_00514	-283	3.6	ACGGACACGATTCAAC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02672	-375	3.6	aCgGAcaCGATTCAaC
Enterobacter sp. 638	Ent638_2826	-283	3.6	ACGGACACGATTCAAC
Erwinia amylovora ATCC 49946	EAM_2286	-257	4.4	ACTGACTCGATTTAGC
Yersinia pestis KIM	y1636	-257	4.4	ACTGACTCGATTTAGC
Serratia proteamaculans 568	Spro_3302	-263	4.3	ACTGACACGATTTAGC
Erwinia carotovora subsp. atroseptica SCRI1043	ECA3022	-258	4.4	ACTGACTCGATTTAGC
Edwardsiella tarda EIB202	ETAE_2379	-135	4.7	GCTGGAGCGATTCGGC
Proteus mirabilis HI4320	PMI1756	-244	4.3	aCTGAcaCGTTTtAGC
Photorhabdus luminescens subsp. laumondii TTO1	plu3083	-254	4.3	ACTGACACGTTTTAGC

Position: -257 Score: 4.4 Sequence: ACTGACTCGATTTAGC Position: -72 Score: 3.5 Sequence: TTTGAATCGATGTGGT Locus tag: YPN_2150
	YPN_2150	-257	4.4	ACTGACTCGATTTAGC
		-72	3.5	TTTGAATCGATGTGGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nuoA
Ortholog function: NADH dehydrogenase I chain A
Escherichia coli str. K-12 substr. MG1655	b2288	-283	3.6	ACGGACACGATTCAAC
Salmonella typhimurium LT2	STM2328	-283	3.6	ACGGACACGATTCAAC
Citrobacter koseri ATCC BAA-895	CKO_00508	-283	3.6	ACGGACACGATTCAAC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02678	-375	3.6	aCgGAcaCGATTCAaC
Enterobacter sp. 638	Ent638_2832	-283	3.6	ACGGACACGATTCAAC
Erwinia amylovora ATCC 49946	EAM_2292	-257	4.4	ACTGACTCGATTTAGC
Yersinia pestis KIM	y1630	-257	4.4	ACTGACTCGATTTAGC
Serratia proteamaculans 568	Spro_3308	-263	4.3	ACTGACACGATTTAGC
Erwinia carotovora subsp. atroseptica SCRI1043	ECA3028	-258	4.4	ACTGACTCGATTTAGC
Edwardsiella tarda EIB202	ETAE_2385	-135	4.7	GCTGGAGCGATTCGGC
Proteus mirabilis HI4320	PMI1762	-244	4.3	aCTGAcaCGTTTtAGC
Photorhabdus luminescens subsp. laumondii TTO1	plu3089	-254	4.3	ACTGACACGTTTTAGC

Position: -157 Score: 5 Sequence: CCTGAATCGATTCATT Locus tag: YPN_2365
	YPN_2365	-157	5	CCTGAATCGATTCATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: manX
Ortholog function: PTS system, mannose-specific IIA component (EC 2.7.1.69) / PTS system, mannose-specific IIB component (EC 2.7.1.69)
Yersinia pestis KIM	y2551	-157	5	CCTGAATCGATTCATT

Position: -102 Score: 4.9 Sequence: ATTGAAACGTTTCAGC Position: -36 Score: 5.3 Sequence: GCTGAAACGATTCAAT Locus tag: YPN_2681
	YPN_2681	-102	4.9	ATTGAAACGTTTCAGC
		-36	5.3	GCTGAAACGATTCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: fruB
Ortholog function: Fructose-specific phosphocarrier protein HPr (EC 2.7.1.69) / PTS system, fructose-specific IIA component (EC 2.7.1.69)
Escherichia coli str. K-12 substr. MG1655	b2169	-35	5.4	GCTGAATCGTTTCAAT
Salmonella typhimurium LT2	STM2206	-35	5.4	GCTGAATCGTTTCAAT
Citrobacter koseri ATCC BAA-895	CKO_00613	26	5.1	CTTGAAACGTTTCAGC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02600	-35	5.3	GCTGAAACGATTCAAT
Enterobacter sp. 638	Ent638_2763	-36	4.8	GCTGAAACGATTCAAG
Erwinia amylovora ATCC 49946	EAM_2223	-35	4.8	GCTGAAACGATTCAAA
Yersinia pestis KIM	y2887	-36	5.3	GCTGAAACGATTCAAT
Serratia proteamaculans 568	Spro_3230	-35	5.3	GCTGAAACGATTCAAT
Erwinia carotovora subsp. atroseptica SCRI1043	ECA2729	-37	5.3	GCTGAAACGATTCAAC
Edwardsiella tarda EIB202	ETAE_2303	-56	5.3	GCTGAAACGATTCAAT
Photorhabdus luminescens subsp. laumondii TTO1	plu1992	-104	5.3	GTTGAAACGTTTCAGT

Position: -277 Score: 4.5 Sequence: GCAGAATCGATTCGGC Locus tag: YPN_2867
	YPN_2867	-277	4.5	GCAGAATCGATTCGGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: gpmA
Ortholog function: Phosphoglycerate mutase (EC 5.4.2.1)
Erwinia amylovora ATCC 49946	EAM_1194	-204	4.5	GGTGAAACGTATCAGT
Yersinia pestis KIM	y3048	-193	4.5	GCAGAATCGATTCGGC
Serratia proteamaculans 568	Spro_1288	-151	4.1	GCCTGAACGATTCAGC
Erwinia carotovora subsp. atroseptica SCRI1043	ECA1382	-150	4.5	GCTGAAACGGTAAAGC
Proteus mirabilis HI4320	PMI0590	-180	4.4	GCTTTATCGATTAAGC

Position: -161 Score: 5.4 Sequence: GCTGAAGCGTTTCAGT Locus tag: YPN_3121
	YPN_3121	-161	5.4	GCTGAAGCGTTTCAGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: epd
Ortholog function: D-erythrose-4-phosphate dehydrogenase (EC 1.2.1.72)
Escherichia coli str. K-12 substr. MG1655	b2927	-137	5.4	GCTGAAGCGTTTCAGT
Salmonella typhimurium LT2	STM3070	-137	5.4	GCTGAAGCGTTTCAGT
Citrobacter koseri ATCC BAA-895	CKO_04297	-137	5.4	GCTGAAGCGTTTCAGT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_03356	-137	5.4	GCTGAAGCGTTTCAGT
Enterobacter sp. 638	Ent638_3340	-139	5.4	GCTGAAGCGTTTCAGT
Erwinia amylovora ATCC 49946	EAM_2813	-131	5.4	GCTGAAGCGTTTCAGT
Yersinia pestis KIM	y3309	-161	5.4	GCTGAAGCGTTTCAGT
Serratia proteamaculans 568	Spro_3946	-211	5.4	GCTGAAGCGTTTCAGT
Erwinia carotovora subsp. atroseptica SCRI1043	ECA3913	-119	5.4	GCTGAAGCGTTTCAGT
Edwardsiella tarda EIB202	ETAE_2958	-136	5.4	GCTGAAGCGTTTCAGT
Proteus mirabilis HI4320	PMI0241	-135	5.1	GCTGAACCGTTTCAGT
Photorhabdus luminescens subsp. laumondii TTO1	plu0955	-139	5.2	GCTGAATCGTTTCATT

Position: -178 Score: 5 Sequence: CTTGAAGCGTTTCAGT Locus tag: YPN_3642
	YPN_3642	-178	5	CTTGAAGCGTTTCAGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: dctA
Ortholog function: Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate, aspartate
Erwinia amylovora ATCC 49946	EAM_3380	-136	4.4	ACTGAAGTGATTCAGC
Yersinia pestis KIM	y3836	-178	5	CTTGAAGCGTTTCAGT
Serratia proteamaculans 568	Spro_0153	-162	4.6	GCTGGCGCGTTTCAGC
Erwinia carotovora subsp. atroseptica SCRI1043	ECA4362	-159	4.3	GCTGACGTGATTCAGC
Edwardsiella tarda EIB202	ETAE_3379	-157	4	TCTTATGCGTTTCAGC

Position: -144 Score: 4.9 Sequence: CTTGAATCAATTCAGC Locus tag: YPN_3770
	YPN_3770	-144	4.9	CTTGAATCAATTCAGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: pfkA
Ortholog function: 6-phosphofructokinase (EC 2.7.1.11)
Escherichia coli str. K-12 substr. MG1655	b3916	-121	5.1	CCTGAATCAATTCAGC
Salmonella typhimurium LT2	STM4062	-122	5.1	CCTGAATCAATTCAGC
Citrobacter koseri ATCC BAA-895	CKO_03085	-128	5.1	CCTGAATCAATTCAGC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_04223	-119	5.1	CCTGAATCAATTCAGC
Enterobacter sp. 638	Ent638_4056	-170	5.1	CCTGAATCAATTCAGC
Erwinia amylovora ATCC 49946	EAM_0103	-128	3.9	CCTCAACCAATTCAGC
Yersinia pestis KIM	y0059	-144	4.9	CTTGAATCAATTCAGC
Serratia proteamaculans 568	Spro_4807	-141	4.9	CTTGAATCAATTCAGC
Erwinia carotovora subsp. atroseptica SCRI1043	ECA4307	-136	5.1	CCTGAATCAATTCAGC
Edwardsiella tarda EIB202	ETAE_3450	-219	5.1	CCTGAATCAATTCAGC
Proteus mirabilis HI4320	PMI3203	-119	5.1	GTTGAATCAATTCAGC
Photorhabdus luminescens subsp. laumondii TTO1	plu4774	-141	5.1	GTTGAATCAATTCAGC

Position: -255 Score: 4.9 Sequence: GCTGAAGCGATACAAC Locus tag: YPN_3892
	YPN_3892	-255	4.9	GCTGAAGCGATACAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: crp
Ortholog function: Catabolite gene activator (cAMP receptor protein), CRP family
Escherichia coli str. K-12 substr. MG1655	b3357	-220	4.3	GCTGAAGCGAGACACC
Salmonella typhimurium LT2	STM3466	-225	4.3	GCTGAAGCGAGACACC
Citrobacter koseri ATCC BAA-895	CKO_04777	-227	4.3	GCTGAAGCGAGACACC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_03743	-224	4.3	GCTGAAGCGAGACACC
Enterobacter sp. 638	Ent638_3784	-228	4.3	GCTGAAGCGAGACACC
Erwinia amylovora ATCC 49946	EAM_3225	-284	4.4	GCTGAAGCGAGACAAC
Yersinia pestis KIM	y3956	-255	4.9	GCTGAAGCGATACAAC
Serratia proteamaculans 568	Spro_4580	-300	4.4	GCTGAAGCGAGACAAC
Erwinia carotovora subsp. atroseptica SCRI1043	ECA4064	-296	4.4	GCTGAAGCGAGACAAC
Edwardsiella tarda EIB202	ETAE_3299	-242	4.5	GCTGAAGCGAGACAGT
Photorhabdus luminescens subsp. laumondii TTO1	plu0395	-241	4.2	GCTGAAACAATACAAG

Position: -168 Score: 4.4 Sequence: GCTGATACCTTTCAGC Locus tag: YPN_3903
	YPN_3903	-168	4.4	GCTGATACCTTTCAGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: nirB
Ortholog function: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)
Escherichia coli str. K-12 substr. MG1655	b3365	-47	4.6	GCTGAATCGTTAAGGT
Salmonella typhimurium LT2	STM3474	-47	4.6	GCTGAATCGTTAAGGT
Citrobacter koseri ATCC BAA-895	CKO_04789	-47	4.6	GCTGAATCGTTAAGGT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_03752	-47	4.6	GCTGAATCGTTAAGGT
Enterobacter sp. 638	Ent638_3793	-47	4.6	GCTGAATCGTTAAGGT
Yersinia pestis KIM	y3945	-168	4.4	GCTGATACCTTTCAGC
Serratia proteamaculans 568	Spro_4595	-169	4.3	ACTGGCTCGTTTCAGC
Proteus mirabilis HI4320	PMI1479	-93	4.7	GCTGAATTGATTAAGC

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of FruR regulog to Yersinia pestis Nepal516

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --