Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of TyrR regulog to Salmonella enterica subsp. enterica serovar Typhi str. E98-2068

Reference regulog properties
Source regulog: TyrR - Enterobacteriales
Regulator type: Transcription factor
Regulator family: TyrR
Regulation mode: activator (repressor)
Biological process: Aromatic amino acid metabolism
Effector: Tyrosine; Phenylalanine
Phylum: Proteobacteria/gamma
Propagated regulon:
Target genome Salmonella enterica subsp. enterica serovar Typhi str. E98-2068
Orthologous TF(s) SentesTyp_010100030707, SentesTyp_010100034948, SentesTyp_010100001563, SentesTyp_010100033211, SentesTyp_010100035363
Regulated genes 8
Built upon 106 sites [see more]
Predicted regulatory interactions in Salmonella enterica subsp. enterica serovar Typhi str. E98-2068
Locus tag Position Score Sequence
Position: -107
Score: 5.8
Sequence: GTGTAAATTATTATTTACAT
Locus tag: SentesTyp_010100001283
SentesTyp_010100001283 -107 5.8 GTGTAAATTATTATTTACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: aroL
Ortholog function: Shikimate kinase III (EC 2.7.1.71)
Escherichia coli str. K-12 substr. MG1655 b0388 -182 5.6 ATGTAATTTATTATTTACAC
-106 5 GTGGAATTTTTTCTTTACAA
Salmonella typhimurium LT2 STM0388 -181 5.4 ATGTAATGAAAAATTTACAG
-107 5.8 GTGTAAATTATTATTTACAT
Citrobacter koseri ATCC BAA-895 CKO_02783 -238 5.4 ATGTAATGTTATTTTTACAC
-163 5 GTGGAATGATTTATTTACAT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_00332 -165 4.6 ATGCAATGATAAGTTTACAT
-101 5.3 GTGTAATTTTTTCTTTACGT
Enterobacter sp. 638 Ent638_0859 -182 4.5 ATGCAATGATTTCTTTACAG
-108 4.9 CTGTAATCCAATTTTTACAA
Erwinia amylovora ATCC 49946 EAM_0932 -126 4.5 CTGTAAATAAAACGTTACTG
Yersinia pestis KIM y0972 -174 5 GTGTATTATTAATTTTACGT
Serratia proteamaculans 568 Spro_1018 -122 4.9 TCGTAAATATTGAAATACAG
Proteus mirabilis HI4320 PMI0371 -57 5.5 TTGTAAATTTTAGATTACAC
Position: -89
Score: 4.2
Sequence: CTGTCAATATTTGTTGACAG
Locus tag: SentesTyp_010100001563
SentesTyp_010100001563 -89 4.2 CTGTCAATATTTGTTGACAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: tyrR
Ortholog function: Transcriptional regulator of aromatic amino acid biosynthesis
Escherichia coli str. K-12 substr. MG1655 b1323 -89 3.7 GTGTCAATGATTGTTGACAG
Salmonella typhimurium LT2 STM1683 -89 4.2 CTGTCAATATTTGTTGACAG
Citrobacter koseri ATCC BAA-895 CKO_01393 -90 4.2 CTGTCAATAATTGTTGACAG
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_01305 -90 4.2 CTGTCAATAATTGTTGACAG
Enterobacter sp. 638 Ent638_2152 -86 3.7 CTGTCAATATCTGTTGACAG
Erwinia amylovora ATCC 49946 EAM_1834 -96 3.9 CTGTCAACTTTTCATGACAG
Serratia proteamaculans 568 Spro_2617 -98 3.6 CTGTCAACTTTTGCTGACAG
Proteus mirabilis HI4320 PMI1369 -96 3.7 GTGTCAACTTTTGCTGACAA
Photorhabdus luminescens subsp. laumondii TTO1 plu2580 -178 3.7 TTTTATAATCAATCTTACAA
Position: -113
Score: 5.3
Sequence: ATGTAAAGTTTATTTTACGT
Locus tag: SentesTyp_010100002578
SentesTyp_010100002578 -113 5.3 ATGTAAAGTTTATTTTACGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: aroF
Ortholog function: 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (EC 2.5.1.54)
Escherichia coli str. K-12 substr. MG1655 b2601 -165 5.4 GTGTAAATTTATCTATACAG
-113 5.4 GTGTAAATAAAAATGTACGA
-90 4 ATGGATTGAAAACTTTACTT
Salmonella typhimurium LT2 STM2670 -164 4.5 GTGTAAAGTTTTTGATACGA
-113 5.3 GTGTAAAGTTTATTTTACGT
-90 4 ATGGATTGAAATCTTTACTT
Citrobacter koseri ATCC BAA-895 CKO_03921 -165 5.3 ATGTAAATTTTTATGTACGA
-112 5.4 ATGTAAAGTAAAATTTACGG
-89 4 GTGGATTGAAATCTTTACCG
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02923 -166 4.9 GTGTAAATATTGTTATACGC
-113 5.7 GTGTAAATTAAAATTTACGG
-90 4 ATGGATTGAATTCTTTACTT
Enterobacter sp. 638 Ent638_3080 -165 5.4 CTGTAATTTTATGTTTACGA
-112 5.7 GTGTAAATTAAAATTTACGG
-89 4 TTGGATTGAAATCTTTACTG
Erwinia amylovora ATCC 49946 EAM_2621 -202 5.3 CTGTAATCTTTTATTTACGC
-106 4.1 CTGGTAATTAATGTGTACAC
-73 4 ATGTACTCATTATGGTACAG
Yersinia pestis KIM y0903 -114 5.2 TAGTAATTATTTATTTACAA
-92 4.5 ATGGATTGAAAACTTTACAT
Serratia proteamaculans 568 Spro_0879 -122 5.1 TGGTAATTTTTTATTTACAG
-99 4.6 TCGGATTTAAAACTTTACAT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA3352 -156 5.2 TGGTAATTTTTTATTTACAC
-133 4.6 GTGGATTTAAATCTTTACGG
Edwardsiella tarda EIB202 ETAE_2837 -129 4.6 GTGTAAAGATGAATGTACGA
-117 4.6 ATGTACGATATTGTTTACAT
-95 4 ATGGATTGAAAAGTTTACTG
Proteus mirabilis HI4320 PMI0387 -244 5.6 GTGTAAAATTAAAATTACAG
-127 5.2 ATGTAAACATATGATTACGA
-85 4.5 ATGGATTGATTTCTTTACAT
Photorhabdus luminescens subsp. laumondii TTO1 plu1262 -140 5.5 TTGTAAACAATAATTTACAG
-98 4.3 TTGGATTGTATTCTTTACGA
Position: -77
Score: 4.9
Sequence: CTGTAAAGTTTTATTGACAG
Locus tag: SentesTyp_010100008382
SentesTyp_010100008382 -77 4.9 CTGTAAAGTTTTATTGACAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: ompF
Ortholog function: outer membrane porin F
Salmonella typhimurium LT2 STM0999 -77 4.7 CTGTAAAGTTTTATTGACGG
Enterobacter sp. 638 Ent638_1448 -77 4.5 CCGGAAATATTTATTGACAG
Position: -111
Score: 5.2
Sequence: TTGTAAATAAATCAATACAA
Locus tag: SentesTyp_010100019671
SentesTyp_010100019671 -111 5.2 TTGTAAATAAATCAATACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: aroP
Ortholog function: Aromatic amino acid transport protein AroP
Escherichia coli str. K-12 substr. MG1655 b0112 -89 5 ATGTAAACAAATTAATACAA
Salmonella typhimurium LT2 STM0150 -108 5.2 TTGTAAATAAATCAATACAA
Citrobacter koseri ATCC BAA-895 CKO_03262 -87 5 GcGTAAAcaTAttaaTACAa
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_00116 -192 4.8 CCGTAAACAAAACAATACAG
Enterobacter sp. 638 Ent638_0658 -87 4.4 CCGTAACGAAATAAATACAT
-64 4.5 ATGGAATTTCATAATTACAC
Erwinia amylovora ATCC 49946 EAM_0745 -187 4.4 GCGTAAAGTTTCCAATACAC
Yersinia pestis KIM y0765 -234 5.3 GTGTAATTAAATGATTACAT
Serratia proteamaculans 568 Spro_4013 -80 4.4 CCGTAAATAAAACAAAACAC
Erwinia carotovora subsp. atroseptica SCRI1043 ECA3791 -93 5.4 CCGTAAAAATAAAATTACAC
Edwardsiella tarda EIB202 ETAE_0657 -91 5.4 ATGTAAAAATAAAATTACGA
Position: -129
Score: 5.2
Sequence: GCGTAAAGTAAAATATACAG
Locus tag: SentesTyp_010100021345
SentesTyp_010100021345 -129 5.2 GCGTAAAGTAAAATATACAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: mtr
Ortholog function: Tryptophan-specific transport protein
Escherichia coli str. K-12 substr. MG1655 b3161 -129 5.3 CTGTAAAATAATATATACAG
Salmonella typhimurium LT2 STM3279 -129 5.2 GCGTAAAGTAAAATATACAG
Citrobacter koseri ATCC BAA-895 CKO_04558 -129 5.1 CCGTAAAGTAAAATATACAG
Enterobacter sp. 638 Ent638_3598 -128 5.2 GCGTAAAGTAATATATACAG
Position: -100
Score: 4.5
Sequence: CTGTAAACATTGTTTTCCAG
Locus tag: SentesTyp_010100033551
SentesTyp_010100033551 -100 4.5 CTGTAAACATTGTTTTCCAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: ipdC
Ortholog function: Indole-3-pyruvate decarboxylase (EC 4.1.1.74)
Salmonella typhimurium LT2 STM2405 -100 4.5 CTGTAAACATTGTTTTCCAG
Citrobacter koseri ATCC BAA-895 CKO_00409 -101 3.8 CTGTAAATCCTGCTTTCCAC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02740 -97 5 GCGTAATTATTGCTTTACAC
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