Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of NrdR regulog to Escherichia coli O157:H7 str. EC4115

Reference regulog properties
Source regulog: NrdR - Enterobacteriales
Regulator type: Transcription factor
Regulator family: NrdR
Regulation mode: repressor
Biological process: Ribonucleotide reductases
Effector: Deoxyribonucleotides
Phylum: Proteobacteria/gamma
Propagated regulon:
Target genome Escherichia coli O157:H7 str. EC4115
Orthologous TF(s) ECH74115_0495
Regulated genes 2
Built upon 70 sites [see more]
Predicted regulatory interactions in Escherichia coli O157:H7 str. EC4115
Locus tag Position Score Sequence
Position: -93
Score: 5.7
Sequence: CCCCTATATATAGTGT
Locus tag: ECH74115_3368
ECH74115_3368 -93 5.7 CCCCTATATATAGTGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nrdA
Ortholog function: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
Escherichia coli str. K-12 substr. MG1655 b2234 -93 5.7 CCCCTATATATAGTGT
-62 3.5 GTACTACAGGTAGTCT
Position: -89
Score: 5.5
Sequence: CAACTACATCTAGTAT
Locus tag: ECH74115_3917
ECH74115_3917 -89 5.5 CAACTACATCTAGTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nrdH
Ortholog function: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
Escherichia coli str. K-12 substr. MG1655 b2673 -120 4.8 TTGCTATATATTGTGT
-89 5.5 CAACTACATCTAGTAT
Salmonella typhimurium LT2 STM2805 -121 4.7 TTCCCATATCTTGTAT
-89 5.5 CAACTACATCTAGTAT
Enterobacter sp. 638 Ent638_3153 -106 4.6 TTCCCATATCTTGTGT
-75 5.5 CAACTACATCTAGTAT
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