Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of FruR regulog to Escherichia coli O157:H7 str. EC4206

Reference regulog properties
Source regulog: FruR - Enterobacteriales
Regulator type: Transcription factor
Regulator family: LacI
Regulation mode: activator (repressor)
Biological process: Central carbohydrate metabolism
Effector: Fructose-1-phosphate; Fructose-1,6-diphosphate
Phylum: Proteobacteria/gamma
Propagated regulon:
Target genome Escherichia coli O157:H7 str. EC4206
Orthologous TF(s) EschericcoliO157_010100004523
Regulated genes 16
Built upon 213 sites [see more]
Predicted regulatory interactions in Escherichia coli O157:H7 str. EC4206
Locus tag Position Score Sequence
Position: -146
Score: 4.4
Sequence: GCTGAAGCGATTTCGC
Locus tag: EschericcoliO157_010100000080
EschericcoliO157_010100000080 -146 4.4 GCTGAAGCGATTTCGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: ppc
Ortholog function: Phosphoenolpyruvate carboxylase (EC 4.1.1.31)
Escherichia coli str. K-12 substr. MG1655 b3956 -146 4.4 GCTGAAGCGATTTCGC
Salmonella typhimurium LT2 STM4119 -209 4.1 GCTGAACCGATTTCGC
Citrobacter koseri ATCC BAA-895 CKO_03038 -166 4.1 GCTGAACCGATTTCGC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_04245 -109 4.4 GCTGAAGCGATTTCGC
Enterobacter sp. 638 Ent638_4030 -126 4.1 GCTGAACCGTTTTCGC
Position: -121
Score: 5.1
Sequence: CCTGAATCAATTCAGC
Locus tag: EschericcoliO157_010100000345
EschericcoliO157_010100000345 -121 5.1 CCTGAATCAATTCAGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: pfkA
Ortholog function: 6-phosphofructokinase (EC 2.7.1.11)
Escherichia coli str. K-12 substr. MG1655 b3916 -121 5.1 CCTGAATCAATTCAGC
Salmonella typhimurium LT2 STM4062 -122 5.1 CCTGAATCAATTCAGC
Citrobacter koseri ATCC BAA-895 CKO_03085 -128 5.1 CCTGAATCAATTCAGC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_04223 -119 5.1 CCTGAATCAATTCAGC
Enterobacter sp. 638 Ent638_4056 -170 5.1 CCTGAATCAATTCAGC
Erwinia amylovora ATCC 49946 EAM_0103 -128 3.9 CCTCAACCAATTCAGC
Yersinia pestis KIM y0059 -144 4.9 CTTGAATCAATTCAGC
Serratia proteamaculans 568 Spro_4807 -141 4.9 CTTGAATCAATTCAGC
Erwinia carotovora subsp. atroseptica SCRI1043 ECA4307 -136 5.1 CCTGAATCAATTCAGC
Edwardsiella tarda EIB202 ETAE_3450 -219 5.1 CCTGAATCAATTCAGC
Proteus mirabilis HI4320 PMI3203 -119 5.1 GTTGAATCAATTCAGC
Photorhabdus luminescens subsp. laumondii TTO1 plu4774 -141 5.1 GTTGAATCAATTCAGC
Position: -123
Score: 4
Sequence: AGTTAACCGATTCAGT
Locus tag: EschericcoliO157_010100002610
EschericcoliO157_010100002610 -123 4 AGTTAACCGATTCAGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: mtlA
Ortholog function: mannitol-specific PTS system, IIABC components
Escherichia coli str. K-12 substr. MG1655 b3599 -123 4 AGTTAACCGATTCAGT
Salmonella typhimurium LT2 STM3685 -124 4.1 AGTTGAACGATTCAGT
Citrobacter koseri ATCC BAA-895 CKO_05054 -120 4.1 AGTTGAACGATTCAGT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03942 -125 3.7 AGCTAAACGATTCAGT
Enterobacter sp. 638 Ent638_0136 -122 3.7 AGTTGAACGATTCGGT
Serratia proteamaculans 568 Spro_0072 -64 4 GCTGGATCGTAACAAC
Position: -47
Score: 4.6
Sequence: GCTGAATCGTTAAGGT
Locus tag: EschericcoliO157_010100004175
EschericcoliO157_010100004175 -47 4.6 GCTGAATCGTTAAGGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nirB
Ortholog function: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)
Escherichia coli str. K-12 substr. MG1655 b3365 -47 4.6 GCTGAATCGTTAAGGT
Salmonella typhimurium LT2 STM3474 -47 4.6 GCTGAATCGTTAAGGT
Citrobacter koseri ATCC BAA-895 CKO_04789 -47 4.6 GCTGAATCGTTAAGGT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03752 -47 4.6 GCTGAATCGTTAAGGT
Enterobacter sp. 638 Ent638_3793 -47 4.6 GCTGAATCGTTAAGGT
Yersinia pestis KIM y3945 -168 4.4 GCTGATACCTTTCAGC
Serratia proteamaculans 568 Spro_4595 -169 4.3 ACTGGCTCGTTTCAGC
Proteus mirabilis HI4320 PMI1479 -93 4.7 GCTGAATTGATTAAGC
Position: -308
Score: 4.2
Sequence: ATTGAACCGATTCACT
Locus tag: EschericcoliO157_010100004748
EschericcoliO157_010100004748 -308 4.2 ATTGAACCGATTCACT
Supported by regulated orthologs from reference regulons
Ortholog gene name: aroP
Ortholog function: Aromatic amino acid transport protein AroP
Escherichia coli str. K-12 substr. MG1655 b0112 -305 4.2 ATTGAACCGATTCACT
Salmonella typhimurium LT2 STM0150 -325 4.4 TCTGAACCGATTCAAC
Citrobacter koseri ATCC BAA-895 CKO_03262 -303 4.4 TCTGAACCGATTCAAC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_00116 -408 4.4 TCTGAACCGATTCAAC
Enterobacter sp. 638 Ent638_0658 -304 4.4 TCTGAACCGATTCACC
Position: -251
Score: 4.2
Sequence: AGTGAATCGGTTCAAT
Locus tag: EschericcoliO157_010100004753
EschericcoliO157_010100004753 -251 4.2 AGTGAATCGGTTCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pdhR
Ortholog function: Transcriptional repressor for pyruvate dehydrogenase, GntR family
Escherichia coli str. K-12 substr. MG1655 b0113 -251 4.2 AGTGAATCGGTTCAAT
Salmonella typhimurium LT2 STM0151 -253 4.5 GTTGAATCGGTTCAGA
Citrobacter koseri ATCC BAA-895 CKO_03260 -253 4.5 GTTGAATCGGTTCAGA
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_00117 -251 4.5 GTTGAATCGGTTCAGA
Enterobacter sp. 638 Ent638_0659 -252 4.4 GGTGAATCGGTTCAGA
Erwinia amylovora ATCC 49946 EAM_0746 -213 4.2 GCTGGCTGGTTTCAAT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA3790 -254 4.1 ATTTAAACGGTTCAGC
Position: -102
Score: 5.1
Sequence: CTTGAAACGTTTCAGC
Position: -35
Score: 5.4
Sequence: GCTGAATCGTTTCAAT
Locus tag: EschericcoliO157_010100007686
EschericcoliO157_010100007686 -102 5.1 CTTGAAACGTTTCAGC
-35 5.4 GCTGAATCGTTTCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: fruB
Ortholog function: Fructose-specific phosphocarrier protein HPr (EC 2.7.1.69) / PTS system, fructose-specific IIA component (EC 2.7.1.69)
Escherichia coli str. K-12 substr. MG1655 b2169 -35 5.4 GCTGAATCGTTTCAAT
Salmonella typhimurium LT2 STM2206 -35 5.4 GCTGAATCGTTTCAAT
Citrobacter koseri ATCC BAA-895 CKO_00613 26 5.1 CTTGAAACGTTTCAGC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02600 -35 5.3 GCTGAAACGATTCAAT
Enterobacter sp. 638 Ent638_2763 -36 4.8 GCTGAAACGATTCAAG
Erwinia amylovora ATCC 49946 EAM_2223 -35 4.8 GCTGAAACGATTCAAA
Yersinia pestis KIM y2887 -36 5.3 GCTGAAACGATTCAAT
Serratia proteamaculans 568 Spro_3230 -35 5.3 GCTGAAACGATTCAAT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA2729 -37 5.3 GCTGAAACGATTCAAC
Edwardsiella tarda EIB202 ETAE_2303 -56 5.3 GCTGAAACGATTCAAT
Photorhabdus luminescens subsp. laumondii TTO1 plu1992 -104 5.3 GTTGAAACGTTTCAGT
Position: -283
Score: 3.6
Sequence: ACGGACACGATTCAAC
Locus tag: EschericcoliO157_010100008371
EschericcoliO157_010100008371 -283 3.6 ACGGACACGATTCAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: nuoA
Ortholog function: NADH dehydrogenase I chain A
Escherichia coli str. K-12 substr. MG1655 b2288 -283 3.6 ACGGACACGATTCAAC
Salmonella typhimurium LT2 STM2328 -283 3.6 ACGGACACGATTCAAC
Citrobacter koseri ATCC BAA-895 CKO_00508 -283 3.6 ACGGACACGATTCAAC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02678 -375 3.6 aCgGAcaCGATTCAaC
Enterobacter sp. 638 Ent638_2832 -283 3.6 ACGGACACGATTCAAC
Erwinia amylovora ATCC 49946 EAM_2292 -257 4.4 ACTGACTCGATTTAGC
Yersinia pestis KIM y1630 -257 4.4 ACTGACTCGATTTAGC
Serratia proteamaculans 568 Spro_3308 -263 4.3 ACTGACACGATTTAGC
Erwinia carotovora subsp. atroseptica SCRI1043 ECA3028 -258 4.4 ACTGACTCGATTTAGC
Edwardsiella tarda EIB202 ETAE_2385 -135 4.7 GCTGGAGCGATTCGGC
Proteus mirabilis HI4320 PMI1762 -244 4.3 aCTGAcaCGTTTtAGC
Photorhabdus luminescens subsp. laumondii TTO1 plu3089 -254 4.3 ACTGACACGTTTTAGC
Position: -134
Score: 4.9
Sequence: GCTGAAACGATAAAGT
Locus tag: EschericcoliO157_010100009436
EschericcoliO157_010100009436 -134 4.9 GCTGAAACGATAAAGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: glk
Ortholog function: Glucokinase (EC 2.7.1.2)
Escherichia coli str. K-12 substr. MG1655 b2388 -134 4.9 GCTGAAACGATAAAGT
Salmonella typhimurium LT2 STM2403 -134 4 GCTGAAACAAGAAAGT
Citrobacter koseri ATCC BAA-895 CKO_00412 -134 4.9 GCTGAAACGATAAAGT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02738 -193 4.9 GCTGAAACGATAAAGT
Enterobacter sp. 638 Ent638_2921 -134 4.5 GCTGAAACGGTAAAGT
Yersinia pestis KIM y1505 -125 4.6 GCTGAAACGTTTTTAT
Serratia proteamaculans 568 Spro_3407 -127 3.9 GCTGAAACGTTTTTTG
Position: -113
Score: 4.4
Sequence: ACTGAAACGTTTTTGC
Locus tag: EschericcoliO157_010100016795
EschericcoliO157_010100016795 -113 4.4 ACTGAAACGTTTTTGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: edd
Ortholog function: Phosphogluconate dehydratase (EC 4.2.1.12)
Escherichia coli str. K-12 substr. MG1655 b1851 -113 4.4 ACTGAAACGTTTTTGC
Salmonella typhimurium LT2 STM1885 -113 4.7 CCTGAAACGATTTTGC
Position: -82
Score: 4.5
Sequence: TCTGAATCGATTCGAT
Locus tag: EschericcoliO157_010100017005
EschericcoliO157_010100017005 -82 4.5 TCTGAATCGATTCGAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: manX
Ortholog function: PTS system, mannose-specific IIA component (EC 2.7.1.69) / PTS system, mannose-specific IIB component (EC 2.7.1.69)
Escherichia coli str. K-12 substr. MG1655 b1817 -82 4.5 TCTGAATCGATTCGAT
Position: -250
Score: 4.6
Sequence: CGTTAAGCGATTCAGC
Locus tag: EschericcoliO157_010100018045
EschericcoliO157_010100018045 -250 4.6 CGTTAAGCGATTCAGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: aceB
Ortholog function: Malate synthase (EC 2.3.3.9)
Escherichia coli str. K-12 substr. MG1655 b4014 -250 4.6 CGTTAAGCGATTCAGC
Salmonella typhimurium LT2 STM4183 -250 4.8 CCTAAAGCGTTTCAGC
Citrobacter koseri ATCC BAA-895 CKO_03906 -250 4.8 CCTAAAGCGTTTCAGC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_04395 -242 4.8 CCTAAAGCGTTTCAGC
Enterobacter sp. 638 Ent638_0218 -252 4.8 CCTAAAGCGTTTCAGC
Position: -221
Score: 4.9
Sequence: CTTGAATGGTTTCAGC
Locus tag: EschericcoliO157_010100027756
EschericcoliO157_010100027756 -221 4.9 CTTGAATGGTTTCAGC
Supported by regulated orthologs from reference regulons
Ortholog gene name: pykF
Ortholog function: Pyruvate kinase (EC 2.7.1.40)
Escherichia coli str. K-12 substr. MG1655 b1676 -221 4.9 CTTGAATGGTTTCAGC
Salmonella typhimurium LT2 STM1378 -221 4.9 CTTGAATGGTTTCAGC
Citrobacter koseri ATCC BAA-895 CKO_01709 -221 4.9 CTTGAATGGTTTCAGC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02133 -221 4.9 CTTGAATGGTTTCAGC
Enterobacter sp. 638 Ent638_1768 -221 5 GGTGAATGGTTTCAGC
Erwinia amylovora ATCC 49946 EAM_1657 -226 4.6 TTTGAATGGTTTCAGC
Yersinia pestis KIM y1944 -258 5.1 GTTGAATGGTTTCAGC
Serratia proteamaculans 568 Spro_2187 -239 5.1 GTTGAATGGTTTCAGC
Erwinia carotovora subsp. atroseptica SCRI1043 ECA1867 -241 4.7 ATTGAATGGTTTCAGC
Edwardsiella tarda EIB202 ETAE_1850 -230 5.1 GTTGAATGGTTTCAGC
Proteus mirabilis HI4320 PMI1405 -269 5 GTTGAAAGGTTTCAGC
Photorhabdus luminescens subsp. laumondii TTO1 plu2613 -344 5.1 GTTGAATGGTTTCAGC