Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of HrcA regulog to Thermotoga lettingae TMO

Reference regulog properties
Source regulog: HrcA - Thermotogales
Regulator type: Transcription factor
Regulator family: HrcA
Regulation mode: repressor
Biological process: Heat shock response
Effector: Heat shock
Phylum: Thermotogae
Propagated regulon:
Target genome Thermotoga lettingae TMO
Orthologous TF(s) Tlet_1782
Regulated genes 3
Built upon 50 sites [see more]
Predicted regulatory interactions in Thermotoga lettingae TMO
Locus tag Position Score Sequence
Position: -169
Score: 5.9
Sequence: GTATCAGTCTATAATTACGAGTGCTAT
Locus tag: Tlet_0014
Tlet_0014 -169 5.9 GTATCAGTCTATAATTACGAGTGCTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: dnaK
Ortholog function: Chaperone Hsp70
Thermotoga maritima MSB8 TM0373 -179 5.7 TTATCATTCAAACATTTCATTTGCTAT
Thermotoga sp. RQ2 TRQ2_0558 -179 5.9 TTATCATTCAAAAGTTTCATTTGCTAT
Thermotoga neapolitana DSM 4359 CTN_0304 -174 6.2 TTATCATTCATAAGTTTCGTTTGCTAT
Thermotoga petrophila RKU-1 Tpet_0544 -179 5.9 TTATCATTCAAAAGTTTCATTTGCTAT
Thermotoga naphthophila RKU-10 Tnap_0168 -179 5.9 TTATCATTCAAAAGTTTCATTTGCTAT
Thermotoga lettingae TMO Tlet_0014 -169 5.9 GTATCAGTCTATAATTACGAGTGCTAT
Thermosipho africanus TCF52B THA_1433 -159 5.2 ATAACAAACTTATGTAACAATTGCTAT
-59 6.3 TTATCACTCTTGACAAAAGACTGCTAA
Thermosipho melanesiensis BI429 Tmel_1128 -157 5.6 ATAACAAACGAATGTTACGATTGCTAT
-57 6.5 TTATCACTCTTGACAATAGAGTGATAA
Fervidobacterium nodosum Rt17-B1 Fnod_1209 -82 6.4 TTATCACTCTTGACAAATGATTGCTAA
Petrotoga mobilis SJ95 Pmob_1649 -205 5.7 TTTTCACTCTTAGATTAAGAGTGATAT
Thermotogales bacterium TBF 19.5.1 Kole_0886 -82 5.6 ATGGCAAACTTGACATTCGATTGCTAA
Position: -57
Score: 6.5
Sequence: TTAGCACTCAAACAGTTCGAGTGATAA
Locus tag: Tlet_0318
Tlet_0318 -57 6.5 TTAGCACTCAAACAGTTCGAGTGATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: groS
Ortholog function: GroES chaperonin
Thermotoga maritima MSB8 TM0505 -48 6.6 TTAGCAGTCGAATGATGAGAGTGCTAA
Thermotoga sp. RQ2 TRQ2_0431 -48 6.4 TTAGCAGTCGAACGATGAGAGTGCTAA
Thermotoga neapolitana DSM 4359 CTN_0166 -52 6.2 TTAGCAGTCATGAGTCGAGAGTGCTAA
Thermotoga neapolitana DSM 4359 CTN_0165 -52 6.2 TTAGCAGTCATGAGTCGAGAGTGCTAA
Thermotoga petrophila RKU-1 Tpet_0416 -48 6.4 TTAGCAGTCGAACGATGAGAGTGCTAA
Thermotoga naphthophila RKU-10 Tnap_0286 -48 6.1 TTAGCAGTCAGACGATGAGAGTGCTAA
Thermotoga lettingae TMO Tlet_0318 -57 6.5 TTAGCACTCAAACAGTTCGAGTGATAA
Thermosipho africanus TCF52B THA_270 -53 5.9 TTAGCAGTCAATGAATTAGAGTGACAA
Thermosipho melanesiensis BI429 Tmel_0053 -54 5.8 TTAGCAGTCGATGATTAAGAGTGACAA
Fervidobacterium nodosum Rt17-B1 Fnod_1544 -61 5.8 TTAACAAACGGAATATTAGAGTGATAA
Petrotoga mobilis SJ95 Pmob_1157 -85 6.9 TTAGCACTCTTAATATTTGATTGCTAA
Thermotogales bacterium TBF 19.5.1 Kole_1626 -71 6.3 TTAGCAGACTCATATAAAGAGTGCTAA
Position: -29
Score: 6.8
Sequence: TTAGCACTCAAATGATGAGAGTGATAA
Locus tag: Tlet_1782
Tlet_1782 -29 6.8 TTAGCACTCAAATGATGAGAGTGATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: hrcA
Ortholog function: Heat shock response regulator, HrcA family
Thermotoga maritima MSB8 TM0851 -30 6.5 TTAGCACTCAAAAGAAGGGAGTGCTAA
Thermotoga sp. RQ2 TRQ2_0076 -30 6.5 TTAGCACTCAAAAGAAGGGAGTGCTAA
Thermotoga neapolitana DSM 4359 CTN_1724 -28 6.6 TTAGCACTCAAAAGAAAGGAGTGCTAA
Thermotoga petrophila RKU-1 Tpet_0076 -30 6.5 TTAGCACTCAAAAGAAGGGAGTGCTAA
Thermotoga naphthophila RKU-10 Tnap_0076 -30 6.5 TTAGCACTCAAAAGAAGGGAGTGCTAA
Thermotoga lettingae TMO Tlet_1782 -29 6.8 TTAGCACTCAAATGATGAGAGTGATAA
Thermosipho africanus TCF52B THA_306 -28 5.8 TTATCAGACAAGGATAAAGAGTGATAA
Thermosipho melanesiensis BI429 Tmel_0089 -51 6.1 TTATCAGACATAGCATAAGAGTGATAA
Fervidobacterium nodosum Rt17-B1 Fnod_1242 -103 5.1 TTGGCAGATGGATAATAAGTTTGCTAA
Petrotoga mobilis SJ95 Pmob_1823 -28 5.8 TTAGCACTTAATATGCGGGAGTGATAA
Thermotogales bacterium TBF 19.5.1 Kole_1384 -28 5.6 TTAGCAGTCTCCAGGGAGGAGTGCTAA
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