Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of NrdR regulog to Thermotoga neapolitana DSM 4359

Reference regulog properties
Source regulog: NrdR - Thermotogales
Regulator type: Transcription factor
Regulator family: NrdR
Regulation mode: repressor
Biological process: Deoxyribonucleotide biosynthesis
Effector: Deoxyribonucleotides
Phylum: Thermotogae
Propagated regulon:
Target genome Thermotoga neapolitana DSM 4359
Orthologous TF(s) CTN_0895
Regulated genes 4
Built upon 60 sites [see more]
Predicted regulatory interactions in Thermotoga neapolitana DSM 4359
Locus tag Position Score Sequence
Position: -54
Score: 5.1
Sequence: CCACAACATATTGTGG
Locus tag: CTN_0313
CTN_0313 -54 5.1 CCACAACATATTGTGG
Supported by regulated orthologs from reference regulons
Ortholog gene name: nrdG
Ortholog function: Anaerobic ribonucleoside-triphosphate reductase-activating protein
Thermotoga maritima MSB8 TM0384 -85 4.1 CAACAATTTTTTGAGA
-55 5.3 CCACAATATATTGTGG
Thermotoga sp. RQ2 TRQ2_0549 -85 4.1 CAACAATTTTTTGAGA
-55 5.3 CCACAATATATTGTGG
Thermotoga neapolitana DSM 4359 CTN_0313 -84 4.5 CAACAATTTATTGAGA
-54 5.1 CCACAACATATTGTGG
Thermotoga petrophila RKU-1 Tpet_0535 -91 4.1 CAACAATTTTTTGAGA
-61 5.3 CCACAATATATTGTGG
Thermotoga naphthophila RKU-10 Tnap_0177 -85 4.1 CAACAATTTTTTGAGA
-55 5.3 CCACAATATATTGTGG
Position: -110
Score: 4.5
Sequence: ATACCATAAGTAGTGT
Locus tag: CTN_0535
CTN_0535 -110 4.5 ATACCATAAGTAGTGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: TM0152
Ortholog function: Conserved hypothetical protein
Thermotoga maritima MSB8 TM0152 -140 5.3 ATACAATATATGGTAT
-109 3.8 ATACTACAAAATGTAC
Thermotoga sp. RQ2 TRQ2_0796 -140 4.6 ATACAATATACGGTAT
-109 4.2 ATACTACAAAATGTAT
Thermotoga neapolitana DSM 4359 CTN_0535 -141 4.2 CTACTTCATGTTGTGT
-110 4.5 ATACCATAAGTAGTGT
Thermotoga petrophila RKU-1 Tpet_0773 -140 4.6 ATACAATATACGGTAT
-109 3.8 ATACTACAAAATGTAC
Thermotoga naphthophila RKU-10 Tnap_0782 -140 4.6 ATACAATATACGGTAT
-109 3.8 ATACTACAAAATGTAC
Thermotogales bacterium TBF 19.5.1 Kole_0584 -154 4.5 TTTCTATATGTTGTGA
-126 4.1 CTCCAATACATTGTGT
Position: -7
Score: 5
Sequence: ACACAATATGTTGTTA
Locus tag: CTN_0571
CTN_0571 -7 5 ACACAATATGTTGTTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: nrdJ
Ortholog function: B12-dependent ribonucleotide reductase (EC 1.17.4.1)
Thermotoga maritima MSB8 TM0118 -64 4.5 CTACCACATGTTGAAT
-34 5.3 ACACAATATGTTGTTT
Thermotoga sp. RQ2 TRQ2_0829 -64 4.3 CTACCAAATGTTGAAT
-34 5 ACACAATATGTTGTTA
Thermotoga neapolitana DSM 4359 CTN_0571 -37 4.4 CCACCACATGTTGAAT
-7 5 AcACAATATgTTGTta
Thermotoga petrophila RKU-1 Tpet_0806 -64 4.3 CTACCAAATGTTGAAT
-34 5 ACACAATATGTTGTTA
Thermotoga naphthophila RKU-10 Tnap_0748 -64 4.3 CTACCAAATGTTGAAT
-34 5 ACACAATATGTTGTTA
Thermotoga lettingae TMO Tlet_0333 -75 5.4 ACACAATATATAGTGT
-45 4.7 ATACAACTTGTAGTAT
Thermosipho africanus TCF52B THA_675 -91 5.3 AAACTATATATTGTAT
-59 5.5 ATACAATATATTGTGG
Thermosipho melanesiensis BI429 Tmel_0606 -103 5.4 ACACAATATATAGTAT
-71 5.5 ATACAATATATTGTGG
Fervidobacterium nodosum Rt17-B1 Fnod_0421 -128 4.5 TAACTATAAGTTGTGT
-98 5.1 ATACTATATATGGTAT
Petrotoga mobilis SJ95 Pmob_1872 -63 4.6 TTTCAATATATTGTCG
-32 4.9 GTACAATATATTGATT
Position: -55
Score: 4.8
Sequence: ACACAACATGTGGTAT
Locus tag: CTN_1290
CTN_1290 -55 4.8 ACACAACATGTGGTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (EC 2.1.1.14)
Thermotoga maritima MSB8 TM1286 -55 4.8 ACACAACATGTGGTAT
-25 4.3 ATACAACAAATGGAGG
Thermotoga sp. RQ2 TRQ2_1533 -55 4.8 ACACAACATGTGGTAT
-25 4.3 ATACAACAAATGGAGG
Thermotoga neapolitana DSM 4359 CTN_1290 -55 4.8 ACACAACATGTGGTAT
-25 4.3 ATACAACAAATGGAGG
Thermotoga petrophila RKU-1 Tpet_1489 -55 4.8 ACACAACATGTGGTAT
-25 4.3 ATACAACAAATGGAGG
Thermotoga naphthophila RKU-10 Tnap_1512 -55 4.8 ACACAACATGTGGTAT
-25 4.3 ATACAACAAATGGAGG