Propagation of CymR regulog to Staphylococcus aureus subsp. aureus MRSA252
| Source regulog: | CymR - Staphylococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | Rrf2 |
| Regulation mode: | repressor |
| Biological process: | Cysteine metabolism |
| Effector: | O-acetyl-L-serine; CysK, cysteine synthetase |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Staphylococcus aureus subsp. aureus MRSA252 |
| Orthologous TF(s) | SAR1706 |
| Regulated genes | 11 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -69
Score: 4.8 Sequence: AATATCCTTGTAATCCGATAAGAATTA
Position: -60
Score: 4.9 Sequence: GTAATCCGATAAGAATTATAGTAATAT
Locus tag: SAR0172
|
||||
| SAR0172 | -69 | 4.8 | AATATCCTTGTAATCCGATAAGAATTA | |
| -60 | 4.9 | GTAATCCGATAAGAATTATAGTAATAT | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: SA0165 | ||||
| Ortholog function: hypothetical protein | ||||
| Staphylococcus aureus subsp. aureus N315 | SA0165 | -59 | 4.9 | GTAATCCGATAAGAATTATAGTAATAT |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP0460 | -69 | 4.8 | CATATCCTTGTAATCTGATAAGATTTA |
|
Position: -41
Score: 5.9 Sequence: TAATTCTTATTAAAATGGTAGGGATTA
Locus tag: SAR0173
|
||||
| SAR0173 | -41 | 5.9 | TAATTCTTATTAAAATGGTAGGGATTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: ssuB | ||||
| Ortholog function: sulfonate ABC transporter, ATPase component | ||||
| Staphylococcus aureus subsp. aureus N315 | SA0166 | -41 | 6 | TAATTCCTATTAAAATAGTAGGGATTA |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP0459 | -41 | 5.7 | CAATTCTTATTAAAACGATAAGAATAA |
|
Position: -77
Score: 4.8 Sequence: TAATCTTGAGTAGATTACTATGATATA
Locus tag: SAR0198
|
||||
| SAR0198 | -77 | 4.8 | TAATCTTGAGTAGATTACTATGATATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: SA0198 | ||||
| Ortholog function: oligopeptide transport ATP-binding protein | ||||
| Staphylococcus aureus subsp. aureus N315 | SA0198 | -77 | 4.8 | TAATCTTGAGTAGATTACTATGATATA |
|
Position: -54
Score: 5.8 Sequence: TTATTCTTAGTATACTGGTCGGAATTA
Locus tag: SAR0401
|
||||
| SAR0401 | -54 | 5.8 | TTATTCTTAGTATACTGGTCGGAATTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: tcyP | ||||
| Ortholog function: L-cystine uptake protein tcyP | ||||
| Staphylococcus aureus subsp. aureus N315 | SA0368 | -54 | 5.8 | TTATTCTTAGCATACTAGTCGGAATTA |
| Staphylococcus capitis SK14 | STACA0001_1450 | -57 | 5.1 | ATATCCTTATTATATATGTCGGAATAC |
| Staphylococcus epidermidis ATCC 12228 | SE2354 | -56 | 5.3 | TTATTCTTATTACATATGTCGGAATAC |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_0042 | -269 | 5 | TAAATACGATATATTTACTAAGGATTT |
| -151 | 4.3 | TTTTACCTACATAACTACTATTTAAAA | ||
| Staphylococcus haemolyticus JCSC1435 | SH2589 | -49 | 5.4 | TTATCCTTATTAAGTATGTCGGAATTA |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP2329 | -63 | 4.6 | ATATCCTTAGTATACGTATCGGATTTC |
| Macrococcus caseolyticus JCSC5402 | MCCL_0267 | 32 | 5.5 | TAATTCTTAgTAtTcTtATAGGAtTac |
|
Position: -88
Score: 5.8 Sequence: TAATTCTTATCTTAAAAGTAAGAATTA
Locus tag: SAR0459
|
||||
| SAR0459 | -88 | 5.8 | TAATTCTTATCTTAAAAGTAAGAATTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: mccA | ||||
| Ortholog function: cystathionine beta-synthase | ||||
| Staphylococcus aureus subsp. aureus N315 | SA0418 | -88 | 5.8 | TAATTCTTATCTGAAAAGTAAGAATTA |
| Staphylococcus capitis SK14 | STACA0001_1480 | -96 | 5.4 | TAATTCATACCTGATAAGTAAGAATTT |
| Staphylococcus epidermidis ATCC 12228 | SE2324 | -96 | 5.7 | TAATTCATATCTGATAAGTAAGAATTA |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_0086 | -92 | 5.6 | TAATCCATATCAGTATAGTAGGAATAA |
| Staphylococcus haemolyticus JCSC1435 | SH2549 | -109 | 5.4 | TAATTCATAGTGATTGAGTAAGAATTA |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP0252 | -144 | 5.1 | GTATGCTTACTGAAAAAGTAGGAATTA |
| -57 | 5 | TAATTCTTATCGGTATAGTAAGGTATT | ||
| Macrococcus caseolyticus JCSC5402 | MCCL_1789 | -46 | 5.6 | TAATCCCGAGTTATCTGATAAGAATAA |
|
Position: -42
Score: 5.8 Sequence: TTATTCCTAGTGGATTAATAAGAATTT
Locus tag: SAR0461
|
||||
| SAR0461 | -42 | 5.8 | TTATTCCTAGTGGATTAATAAGAATTT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metN2 | ||||
| Ortholog function: methionine ABC transporter paralog, ATP-binding protein MetN2 | ||||
| Staphylococcus aureus subsp. aureus N315 | SA0420 | -42 | 5.8 | TTATTCCTAGTGGATTAATAAGAATTT |
| Staphylococcus capitis SK14 | STACA0001_1483 | -43 | 5.4 | ATATTCAGATAAGTATAATCAGAATTG |
| Staphylococcus epidermidis ATCC 12228 | SE2322 | -42 | 5.3 | ATATTCAGATAATTTTAATCGGAAATT |
|
Position: -55
Score: 5.1 Sequence: TATATCCGATAAATAAACTAAGATTTC
Locus tag: SAR0514
|
||||
| SAR0514 | -55 | 5.1 | TATATCCGATAAATAAACTAAGATTTC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysK | ||||
| Ortholog function: cysteine synthase | ||||
| Staphylococcus aureus subsp. aureus N315 | SA0471 | -55 | 5.1 | TATATCCGATAAATAAACTAAGATTTC |
| Staphylococcus capitis SK14 | STACA0001_2088 | -57 | 4.9 | TATATCCGATAGGAAAACTAAGTTTTA |
| Staphylococcus epidermidis ATCC 12228 | SE2270 | -58 | 4.8 | TATATCCGATAGAAAAACTAAGTATTG |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_0164 | -143 | 4.4 | GATATCCGATGAAATAGCTAAGATATA |
| Staphylococcus haemolyticus JCSC1435 | SH2497 | -56 | 4.9 | TATATCCGATAGAAAAACTAAGTTTTA |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP2243 | -55 | 5.1 | TATATCCGATTGAAAAAGTAGGTTTTA |
| Macrococcus caseolyticus JCSC5402 | MCCL_1900 | -50 | 5.4 | TAAATCCGATAAGCGTAATAAGAATAA |
|
Position: -42
Score: 5.2 Sequence: TAATACATACTAAACTTATCGGAAATT
Locus tag: SAR2132
|
||||
| SAR2132 | -42 | 5.2 | TAATACATACTAAACTTATCGGAAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: SA1850 | ||||
| Ortholog function: putative transporter for thiosulphate | ||||
| Staphylococcus aureus subsp. aureus N315 | SA1850 | -40 | 5.2 | TAATACATACTAAACTTATCGGAAATG |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_1551 | -38 | 4.8 | TAAAACTTACTAACATTATCGGAAAAG |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP0834 | -37 | 5.1 | TTAATCTTATTGATTTTATCGGGAAAG |
|
Position: -243
Score: 4.8 Sequence: GAATTATTACTTATTCTATCGGTTTTA
Locus tag: SAR2222
|
||||
| SAR2222 | -243 | 4.8 | GAATTATTACTTATTCTATCGGTTTTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: luxS | ||||
| Ortholog function: S-ribosylhomocysteinase | ||||
| Staphylococcus aureus subsp. aureus N315 | SA1936 | -244 | 4.8 | GAATTATTACTTATTCTATCGGTTTTA |
| Staphylococcus capitis SK14 | STACA0001_0838 | -193 | 5.5 | TAATTATTACTTATTCTATCGGAATAA |
| Staphylococcus epidermidis ATCC 12228 | SE1732 | -182 | 5.6 | TAATTATTACTTATTTTATCGGATTTA |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_1637 | -110 | 4.7 | TTATCCCGAGTAAACTTATCAACTTAA |
| Staphylococcus haemolyticus JCSC1435 | SH0901 | -182 | 5.6 | TAATTATTACTTATTTTATCGGATTTA |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP0751 | -159 | 5.1 | TAATTATTACTTATTCTATCGGGTTTA |
| Macrococcus caseolyticus JCSC5402 | MCCL_1791 | -46 | 5.6 | TAATCCCGAGTTATCTGATAAGAATAA |
|
Position: -40
Score: 6.2 Sequence: TTATTCCGATTAGAATAATAAGAATAA
Locus tag: SAR2504
|
||||
| SAR2504 | -40 | 6.2 | TTATTCCGATTAGAATAATAAGAATAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: tcyA | ||||
| Ortholog function: L-cystine uptake ABC transporter, L-cystine-binding protein TcyA | ||||
| Staphylococcus aureus subsp. aureus N315 | SA2202 | -40 | 6.2 | TTATTCCGATTAGAATAATAAGAATAA |
| Staphylococcus capitis SK14 | STACA0001_1063 | -40 | 6 | TTATTCCGATTAGAATAATAAGATTAA |
| Staphylococcus epidermidis ATCC 12228 | SE1993 | -40 | 6.2 | TTATTCCGATTAGAATAATAAGAATAA |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_1910 | -40 | 5.4 | TTATTCCGATGAGAATGATAAGGATAA |
| Staphylococcus haemolyticus JCSC1435 | SH0639 | -41 | 5.9 | TTATTCTGACTAATCTAATAGGAATAT |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP0242 | -37 | 5.8 | TTATTCCGATAAGAATAATAAGAATAG |
| Macrococcus caseolyticus JCSC5402 | MCCL_1425 | -38 | 5.3 | CTATTCCGAGTAAATTGATATGAATAG |
|
Position: -254
Score: 4.7 Sequence: TAATAAATAGTAAATAAATAAAAAATA
Locus tag: SAR2698
|
||||
| SAR2698 | -254 | 4.7 | TAATAAATAGTAAATAAATAAAAAATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysJ | ||||
| Ortholog function: sulfite reductase [NADPH] flavoprotein, alpha-component | ||||
| Staphylococcus aureus subsp. aureus N315 | SA2413 | -257 | 4.7 | TAATAAATAGTAAATAAATAAAAAATA |
| Staphylococcus capitis SK14 | STACA0001_1811 | -246 | 4.7 | TAAAGCATAGTATTCCGATAAGATATA |
| Staphylococcus epidermidis ATCC 12228 | SE2180 | -273 | 4.7 | CAAAACATAGTATTCCGATAAGAAATA |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_0059 | -134 | 5.4 | TAATTCTTAGTAAACCTATTGGAATTA |
| -52 | 5.9 | TAATTCCTACTAAAAAACTAAGAATAA | ||
| Staphylococcus haemolyticus JCSC1435 | SH0414 | -152 | 4.5 | TAAAACATAGTATTCTGATATGTTTTG |
| -68 | 5.6 | TTATTCTGACAATTCTGATAGGTATTA | ||
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP2408 | -152 | 4.5 | AATAACCTAGTATTCGTATCGGAAATA |
| -58 | 4.6 | TTAAACCTATTTAGACAATAATTATAA | ||