Propagation of CymR regulog to Staphylococcus epidermidis ATCC 12228
| Source regulog: | CymR - Staphylococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | Rrf2 |
| Regulation mode: | repressor |
| Biological process: | Cysteine metabolism |
| Effector: | O-acetyl-L-serine; CysK, cysteine synthetase |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Staphylococcus epidermidis ATCC 12228 |
| Orthologous TF(s) | SE1308 |
| Regulated genes | 10 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -35
Score: 4.6 Sequence: AATACCTTAGTATTTATATCGGAAAAG
Locus tag: SE1646
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| SE1646 | -35 | 4.6 | AATACCTTAGTATTTATATCGGAAAAG | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: SA1850 | ||||
| Ortholog function: putative transporter for thiosulphate | ||||
| Staphylococcus epidermidis ATCC 12228 | SE1646 | -35 | 4.6 | AATACCTTAGTATTTATATCGGAAAAG |
| Macrococcus caseolyticus JCSC5402 | MCCL_0379 | -40 | 5.8 | TATTTCTTACTAAATCTATCGGAATTA |
|
Position: -182
Score: 5.6 Sequence: TAATTATTACTTATTTTATCGGATTTA
Locus tag: SE1732
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| SE1732 | -182 | 5.6 | TAATTATTACTTATTTTATCGGATTTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: luxS | ||||
| Ortholog function: S-ribosylhomocysteinase | ||||
| Staphylococcus aureus subsp. aureus N315 | SA1936 | -244 | 4.8 | GAATTATTACTTATTCTATCGGTTTTA |
| Staphylococcus capitis SK14 | STACA0001_0838 | -193 | 5.5 | TAATTATTACTTATTCTATCGGAATAA |
| Staphylococcus epidermidis ATCC 12228 | SE1732 | -182 | 5.6 | TAATTATTACTTATTTTATCGGATTTA |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_1637 | -110 | 4.7 | TTATCCCGAGTAAACTTATCAACTTAA |
| Staphylococcus haemolyticus JCSC1435 | SH0901 | -182 | 5.6 | TAATTATTACTTATTTTATCGGATTTA |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP0751 | -159 | 5.1 | TAATTATTACTTATTCTATCGGGTTTA |
| Macrococcus caseolyticus JCSC5402 | MCCL_1791 | -46 | 5.6 | TAATCCCGAGTTATCTGATAAGAATAA |
|
Position: -65
Score: 4.4 Sequence: TAAAGTCGAGTGTTAAACTATGAATAA
Locus tag: SE1858
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| SE1858 | -65 | 4.4 | TAAAGTCGAGTGTTAAACTATGAATAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: SA2080 | ||||
| Ortholog function: putative acyl-CoA dehydrogenase | ||||
| Staphylococcus aureus subsp. aureus N315 | SA2080 | -62 | 4.6 | TAAAGTCGAGTGTTAAACTAGGAATAA |
| Staphylococcus capitis SK14 | STACA0001_1208 | -57 | 4.2 | AAAAGTCGAGTGTTAAACTAGGATTAA |
| Staphylococcus epidermidis ATCC 12228 | SE1858 | -65 | 4.4 | TAAAGTCGAGTGTTAAACTATGAATAA |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_1777 | -56 | 4.4 | TTAATCCGAGTGATACACTAAACTTAA |
| Staphylococcus haemolyticus JCSC1435 | SH0767 | -266 | 4.4 | TAATGTCGAGTGATAAACTAGGTTTAA |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP0622 | -110 | 5.1 | TAAATCTTATCGGTAAAGTAAGGATTT |
| Macrococcus caseolyticus JCSC5402 | MCCL_0131 | -256 | 4.5 | TATTTCCTAGATAATAAATAATGTATT |
|
Position: -40
Score: 6.2 Sequence: TTATTCCGATTAGAATAATAAGAATAA
Locus tag: SE1993
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| SE1993 | -40 | 6.2 | TTATTCCGATTAGAATAATAAGAATAA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: tcyA | ||||
| Ortholog function: L-cystine uptake ABC transporter, L-cystine-binding protein TcyA | ||||
| Staphylococcus aureus subsp. aureus N315 | SA2202 | -40 | 6.2 | TTATTCCGATTAGAATAATAAGAATAA |
| Staphylococcus capitis SK14 | STACA0001_1063 | -40 | 6 | TTATTCCGATTAGAATAATAAGATTAA |
| Staphylococcus epidermidis ATCC 12228 | SE1993 | -40 | 6.2 | TTATTCCGATTAGAATAATAAGAATAA |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_1910 | -40 | 5.4 | TTATTCCGATGAGAATGATAAGGATAA |
| Staphylococcus haemolyticus JCSC1435 | SH0639 | -41 | 5.9 | TTATTCTGACTAATCTAATAGGAATAT |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP0242 | -37 | 5.8 | TTATTCCGATAAGAATAATAAGAATAG |
| Macrococcus caseolyticus JCSC5402 | MCCL_1425 | -38 | 5.3 | CTATTCCGAGTAAATTGATATGAATAG |
|
Position: -273
Score: 4.7 Sequence: CAAAACATAGTATTCCGATAAGAAATA
Locus tag: SE2180
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| SE2180 | -273 | 4.7 | CAAAACATAGTATTCCGATAAGAAATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysJ | ||||
| Ortholog function: sulfite reductase [NADPH] flavoprotein, alpha-component | ||||
| Staphylococcus aureus subsp. aureus N315 | SA2413 | -257 | 4.7 | TAATAAATAGTAAATAAATAAAAAATA |
| Staphylococcus capitis SK14 | STACA0001_1811 | -246 | 4.7 | TAAAGCATAGTATTCCGATAAGATATA |
| Staphylococcus epidermidis ATCC 12228 | SE2180 | -273 | 4.7 | CAAAACATAGTATTCCGATAAGAAATA |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_0059 | -134 | 5.4 | TAATTCTTAGTAAACCTATTGGAATTA |
| -52 | 5.9 | TAATTCCTACTAAAAAACTAAGAATAA | ||
| Staphylococcus haemolyticus JCSC1435 | SH0414 | -152 | 4.5 | TAAAACATAGTATTCTGATATGTTTTG |
| -68 | 5.6 | TTATTCTGACAATTCTGATAGGTATTA | ||
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP2408 | -152 | 4.5 | AATAACCTAGTATTCGTATCGGAAATA |
| -58 | 4.6 | TTAAACCTATTTAGACAATAATTATAA | ||
|
Position: -68
Score: 5 Sequence: TTATTCTGACAATTCTGATATGTTTTG
Locus tag: SE2181
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| SE2181 | -68 | 5 | TTATTCTGACAATTCTGATATGTTTTG | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysH | ||||
| Ortholog function: phosphoadenosine phosphosulfate reductase | ||||
| Staphylococcus capitis SK14 | STACA0001_1812 | -71 | 5.5 | TTATTCTGACAATTCAGATAGGAATTT |
| Staphylococcus epidermidis ATCC 12228 | SE2181 | -68 | 5 | TTATTCTGACAATTCTGATATGTTTTG |
| Staphylococcus haemolyticus JCSC1435 | SH0413 | -152 | 4.5 | TAAAACATAGTATTCTGATATGTTTTG |
| -68 | 5.6 | TTATTCTGACAATTCTGATAGGTATTA | ||
|
Position: -58
Score: 4.8 Sequence: TATATCCGATAGAAAAACTAAGTATTG
Locus tag: SE2270
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| SE2270 | -58 | 4.8 | TATATCCGATAGAAAAACTAAGTATTG | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cysK | ||||
| Ortholog function: cysteine synthase | ||||
| Staphylococcus aureus subsp. aureus N315 | SA0471 | -55 | 5.1 | TATATCCGATAAATAAACTAAGATTTC |
| Staphylococcus capitis SK14 | STACA0001_2088 | -57 | 4.9 | TATATCCGATAGGAAAACTAAGTTTTA |
| Staphylococcus epidermidis ATCC 12228 | SE2270 | -58 | 4.8 | TATATCCGATAGAAAAACTAAGTATTG |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_0164 | -143 | 4.4 | GATATCCGATGAAATAGCTAAGATATA |
| Staphylococcus haemolyticus JCSC1435 | SH2497 | -56 | 4.9 | TATATCCGATAGAAAAACTAAGTTTTA |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP2243 | -55 | 5.1 | TATATCCGATTGAAAAAGTAGGTTTTA |
| Macrococcus caseolyticus JCSC5402 | MCCL_1900 | -50 | 5.4 | TAAATCCGATAAGCGTAATAAGAATAA |
|
Position: -42
Score: 5.3 Sequence: ATATTCAGATAATTTTAATCGGAAATT
Locus tag: SE2322
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| SE2322 | -42 | 5.3 | ATATTCAGATAATTTTAATCGGAAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metN2 | ||||
| Ortholog function: methionine ABC transporter paralog, ATP-binding protein MetN2 | ||||
| Staphylococcus aureus subsp. aureus N315 | SA0420 | -42 | 5.8 | TTATTCCTAGTGGATTAATAAGAATTT |
| Staphylococcus capitis SK14 | STACA0001_1483 | -43 | 5.4 | ATATTCAGATAAGTATAATCAGAATTG |
| Staphylococcus epidermidis ATCC 12228 | SE2322 | -42 | 5.3 | ATATTCAGATAATTTTAATCGGAAATT |
|
Position: -96
Score: 5.7 Sequence: TAATTCATATCTGATAAGTAAGAATTA
Locus tag: SE2324
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| SE2324 | -96 | 5.7 | TAATTCATATCTGATAAGTAAGAATTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: mccA | ||||
| Ortholog function: cystathionine beta-synthase | ||||
| Staphylococcus aureus subsp. aureus N315 | SA0418 | -88 | 5.8 | TAATTCTTATCTGAAAAGTAAGAATTA |
| Staphylococcus capitis SK14 | STACA0001_1480 | -96 | 5.4 | TAATTCATACCTGATAAGTAAGAATTT |
| Staphylococcus epidermidis ATCC 12228 | SE2324 | -96 | 5.7 | TAATTCATATCTGATAAGTAAGAATTA |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_0086 | -92 | 5.6 | TAATCCATATCAGTATAGTAGGAATAA |
| Staphylococcus haemolyticus JCSC1435 | SH2549 | -109 | 5.4 | TAATTCATAGTGATTGAGTAAGAATTA |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP0252 | -144 | 5.1 | GTATGCTTACTGAAAAAGTAGGAATTA |
| -57 | 5 | TAATTCTTATCGGTATAGTAAGGTATT | ||
| Macrococcus caseolyticus JCSC5402 | MCCL_1789 | -46 | 5.6 | TAATCCCGAGTTATCTGATAAGAATAA |
|
Position: -56
Score: 5.3 Sequence: TTATTCTTATTACATATGTCGGAATAC
Locus tag: SE2354
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| SE2354 | -56 | 5.3 | TTATTCTTATTACATATGTCGGAATAC | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: tcyP | ||||
| Ortholog function: L-cystine uptake protein tcyP | ||||
| Staphylococcus aureus subsp. aureus N315 | SA0368 | -54 | 5.8 | TTATTCTTAGCATACTAGTCGGAATTA |
| Staphylococcus capitis SK14 | STACA0001_1450 | -57 | 5.1 | ATATCCTTATTATATATGTCGGAATAC |
| Staphylococcus epidermidis ATCC 12228 | SE2354 | -56 | 5.3 | TTATTCTTATTACATATGTCGGAATAC |
| Staphylococcus carnosus subsp. carnosus TM300 | Sca_0042 | -269 | 5 | TAAATACGATATATTTACTAAGGATTT |
| -151 | 4.3 | TTTTACCTACATAACTACTATTTAAAA | ||
| Staphylococcus haemolyticus JCSC1435 | SH2589 | -49 | 5.4 | TTATCCTTATTAAGTATGTCGGAATTA |
| Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 | SSP2329 | -63 | 4.6 | ATATCCTTAGTATACGTATCGGATTTC |
| Macrococcus caseolyticus JCSC5402 | MCCL_0267 | 32 | 5.5 | TAATTCTTAgTAtTcTtATAGGAtTac |