Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of CymR regulog to Staphylococcus epidermidis RP62A

Reference regulog properties
Source regulog: CymR - Staphylococcaceae
Regulator type: Transcription factor
Regulator family: Rrf2
Regulation mode: repressor
Biological process: Cysteine metabolism
Effector: O-acetyl-L-serine; CysK, cysteine synthetase
Phylum: Firmicutes
Propagated regulon:
Target genome Staphylococcus epidermidis RP62A
Orthologous TF(s) SERP1189
Regulated genes 7
Built upon 69 sites [see more]
Predicted regulatory interactions in Staphylococcus epidermidis RP62A
Locus tag Position Score Sequence
Position: -56
Score: 5.3
Sequence: TTATTCTTATTACATATGTCGGAATAC
Locus tag: SERP0063
SERP0063 -56 5.3 TTATTCTTATTACATATGTCGGAATAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyP
Ortholog function: L-cystine uptake protein tcyP
Staphylococcus aureus subsp. aureus N315 SA0368 -54 5.8 TTATTCTTAGCATACTAGTCGGAATTA
Staphylococcus capitis SK14 STACA0001_1450 -57 5.1 ATATCCTTATTATATATGTCGGAATAC
Staphylococcus epidermidis ATCC 12228 SE2354 -56 5.3 TTATTCTTATTACATATGTCGGAATAC
Staphylococcus carnosus subsp. carnosus TM300 Sca_0042 -269 5 TAAATACGATATATTTACTAAGGATTT
-151 4.3 TTTTACCTACATAACTACTATTTAAAA
Staphylococcus haemolyticus JCSC1435 SH2589 -49 5.4 TTATCCTTATTAAGTATGTCGGAATTA
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP2329 -63 4.6 ATATCCTTAGTATACGTATCGGATTTC
Macrococcus caseolyticus JCSC5402 MCCL_0267 32 5.5 TAATTCTTAgTAtTcTtATAGGAtTac
Position: -96
Score: 5.7
Sequence: TAATTCATATCTGATAAGTAAGAATTA
Locus tag: SERP0094
SERP0094 -96 5.7 TAATTCATATCTGATAAGTAAGAATTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: mccA
Ortholog function: cystathionine beta-synthase
Staphylococcus aureus subsp. aureus N315 SA0418 -88 5.8 TAATTCTTATCTGAAAAGTAAGAATTA
Staphylococcus capitis SK14 STACA0001_1480 -96 5.4 TAATTCATACCTGATAAGTAAGAATTT
Staphylococcus epidermidis ATCC 12228 SE2324 -96 5.7 TAATTCATATCTGATAAGTAAGAATTA
Staphylococcus carnosus subsp. carnosus TM300 Sca_0086 -92 5.6 TAATCCATATCAGTATAGTAGGAATAA
Staphylococcus haemolyticus JCSC1435 SH2549 -109 5.4 TAATTCATAGTGATTGAGTAAGAATTA
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP0252 -144 5.1 GTATGCTTACTGAAAAAGTAGGAATTA
-57 5 TAATTCTTATCGGTATAGTAAGGTATT
Macrococcus caseolyticus JCSC5402 MCCL_1789 -46 5.6 TAATCCCGAGTTATCTGATAAGAATAA
Position: -58
Score: 4.8
Sequence: TATATCCGATAGAAAAACTAAGTATTG
Locus tag: SERP0152
SERP0152 -58 4.8 TATATCCGATAGAAAAACTAAGTATTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysK
Ortholog function: cysteine synthase
Staphylococcus aureus subsp. aureus N315 SA0471 -55 5.1 TATATCCGATAAATAAACTAAGATTTC
Staphylococcus capitis SK14 STACA0001_2088 -57 4.9 TATATCCGATAGGAAAACTAAGTTTTA
Staphylococcus epidermidis ATCC 12228 SE2270 -58 4.8 TATATCCGATAGAAAAACTAAGTATTG
Staphylococcus carnosus subsp. carnosus TM300 Sca_0164 -143 4.4 GATATCCGATGAAATAGCTAAGATATA
Staphylococcus haemolyticus JCSC1435 SH2497 -56 4.9 TATATCCGATAGAAAAACTAAGTTTTA
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP2243 -55 5.1 TATATCCGATTGAAAAAGTAGGTTTTA
Macrococcus caseolyticus JCSC5402 MCCL_1900 -50 5.4 TAAATCCGATAAGCGTAATAAGAATAA
Position: -182
Score: 5.1
Sequence: TAATTATTACTTATTTTATCGGATTGA
Locus tag: SERP1741
SERP1741 -182 5.1 TAATTATTACTTATTTTATCGGATTGA
Supported by regulated orthologs from reference regulons
Ortholog gene name: luxS
Ortholog function: S-ribosylhomocysteinase
Staphylococcus aureus subsp. aureus N315 SA1936 -244 4.8 GAATTATTACTTATTCTATCGGTTTTA
Staphylococcus capitis SK14 STACA0001_0838 -193 5.5 TAATTATTACTTATTCTATCGGAATAA
Staphylococcus epidermidis ATCC 12228 SE1732 -182 5.6 TAATTATTACTTATTTTATCGGATTTA
Staphylococcus carnosus subsp. carnosus TM300 Sca_1637 -110 4.7 TTATCCCGAGTAAACTTATCAACTTAA
Staphylococcus haemolyticus JCSC1435 SH0901 -182 5.6 TAATTATTACTTATTTTATCGGATTTA
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP0751 -159 5.1 TAATTATTACTTATTCTATCGGGTTTA
Macrococcus caseolyticus JCSC5402 MCCL_1791 -46 5.6 TAATCCCGAGTTATCTGATAAGAATAA
Position: -40
Score: 6.2
Sequence: TTATTCCGATTAGAATAATAAGAATAA
Locus tag: SERP2005
SERP2005 -40 6.2 TTATTCCGATTAGAATAATAAGAATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: tcyA
Ortholog function: L-cystine uptake ABC transporter, L-cystine-binding protein TcyA
Staphylococcus aureus subsp. aureus N315 SA2202 -40 6.2 TTATTCCGATTAGAATAATAAGAATAA
Staphylococcus capitis SK14 STACA0001_1063 -40 6 TTATTCCGATTAGAATAATAAGATTAA
Staphylococcus epidermidis ATCC 12228 SE1993 -40 6.2 TTATTCCGATTAGAATAATAAGAATAA
Staphylococcus carnosus subsp. carnosus TM300 Sca_1910 -40 5.4 TTATTCCGATGAGAATGATAAGGATAA
Staphylococcus haemolyticus JCSC1435 SH0639 -41 5.9 TTATTCTGACTAATCTAATAGGAATAT
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP0242 -37 5.8 TTATTCCGATAAGAATAATAAGAATAG
Macrococcus caseolyticus JCSC5402 MCCL_1425 -38 5.3 CTATTCCGAGTAAATTGATATGAATAG
Position: -273
Score: 4.7
Sequence: CAAAACATAGTATTCCGATAAGAAATA
Locus tag: SERP2191
SERP2191 -273 4.7 CAAAACATAGTATTCCGATAAGAAATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysJ
Ortholog function: sulfite reductase [NADPH] flavoprotein, alpha-component
Staphylococcus aureus subsp. aureus N315 SA2413 -257 4.7 TAATAAATAGTAAATAAATAAAAAATA
Staphylococcus capitis SK14 STACA0001_1811 -246 4.7 TAAAGCATAGTATTCCGATAAGATATA
Staphylococcus epidermidis ATCC 12228 SE2180 -273 4.7 CAAAACATAGTATTCCGATAAGAAATA
Staphylococcus carnosus subsp. carnosus TM300 Sca_0059 -134 5.4 TAATTCTTAGTAAACCTATTGGAATTA
-52 5.9 TAATTCCTACTAAAAAACTAAGAATAA
Staphylococcus haemolyticus JCSC1435 SH0414 -152 4.5 TAAAACATAGTATTCTGATATGTTTTG
-68 5.6 TTATTCTGACAATTCTGATAGGTATTA
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP2408 -152 4.5 AATAACCTAGTATTCGTATCGGAAATA
-58 4.6 TTAAACCTATTTAGACAATAATTATAA
Position: -68
Score: 5
Sequence: TTATTCTGACAATTCTGATATGTTTTG
Locus tag: SERP2192
SERP2192 -68 5 TTATTCTGACAATTCTGATATGTTTTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: cysH
Ortholog function: phosphoadenosine phosphosulfate reductase
Staphylococcus capitis SK14 STACA0001_1812 -71 5.5 TTATTCTGACAATTCAGATAGGAATTT
Staphylococcus epidermidis ATCC 12228 SE2181 -68 5 TTATTCTGACAATTCTGATATGTTTTG
Staphylococcus haemolyticus JCSC1435 SH0413 -152 4.5 TAAAACATAGTATTCTGATATGTTTTG
-68 5.6 TTATTCTGACAATTCTGATAGGTATTA
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