Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagated regulons of Escherichia coli O157:H7 str. EC4486

Type Regulator Effector Pathway Genes Sites
TF AbgR p-aminobenzoyl-glutamate p-aminobenzoyl-glutamate utilization 2 4
TF AcrR Rhodamine 6G; Ethidium bromide; Proflavin Multidrug resistance 2 2
TF AgaR N-acetylgalactosamine-6-phosphate; Galactosamine-6-phosphate N-acetylgalactosamine utilization 2 3
TF AllR Allantoin Allantoin utilization 3 3
TF AraC Arabinose Arabinose utilization 3 4
TF ArgR Arginine Arginine biosynthesis; Arginine degradation 14 29
TF AscG Cellobiose-6-phosphate; Beta-glucoside-6-phosphate Beta-glucosides utilization; Cellobiose utilization 2 3
TF BetI Choline Glycine betaine synthesis 2 2
TF Crp Cyclic 3',5'-AMP Carbon catabolism 241 621
TF CueR Copper ion, (Cu+) Copper resistance 2 2
TF DeoR Deoxyribonucleoside utilization 3 4
TF EbgR Beta-galactosides Galactosides utilization 2 2
TF ExuR Galacturonate Galacturonate utilization 4 6
TF FabR Unsaturated acyl-ACP; Unsaturated acyl-CoA Fatty acid biosynthesis 3 3
TF FadR Palmitoyl-CoA; Oleoyl-CoA Fatty acid degradation 10 15
TF Fnr Oxygen Energy metabolism; Anaerobic metabolism 101 183
TF FruR Fructose-1-phosphate; Fructose-1,6-diphosphate Central carbohydrate metabolism 18 21
TF FucR L-fuculose-1-phosphate Fucose utilization 2 3
TF Fur Iron ion, (Fe2+) Iron homeostasis 37 135
TF GalR/GalS Galactose Galactose utilization 5 6
TF GcvA Glycine Glycine metabolism 1 1
TF GlpR Glycerol 3-phosphate Glycerol utilization 5 6
TF GntR Gluconate Gluconate utilization 3 6
TF HexR 2-keto-3-deoxy-6-phosphogluconate Central carbohydrate metabolism 2 2
TF IclR Pyruvate; Glyoxylate Glyoxylate bypass 1 1
TF IlvY 2-Acetolactate Branched-chain amino acid biosynthesis 2 4
TF IscR Iron-sulfur cluster redox state Iron-sulfur cluster biogenesis 2 3
TF KdgR 2-keto-3-deoxygluconate Pectin and polygalacturonate utlization 6 8
TF LeuO Guanosine 3',5'-bis(diphosphate) 2 4
TF LexA DNA damage SOS response 21 25
TF LldR L-lactate Lactate utilization 1 1
TF LsrR 4,5-dihydroxypentan-2,3-dione Quorum sensing; Biofilm formation 2 4
TF LysR LL-2,6-Diaminopimelate Lysine biosynthesis 2 2
TF MalI Maltose utilization 2 3
TF MarR Salicylate; Tetracycline; Chloramphenicol Antibiotic resistance 1 1
TF MetR Homocysteine Methionine biosynthesis 4 5
TF MntR Manganese ion, (Mn2+) Manganese homeostasis 3 3
TF ModE Molybdate Molybdopterin biosynthesis; Molybdenum homeostasis 4 4
TF MprA 2,4-Dinitrophenol; Carbonyl cyanide m-chlorophenylhydrazone Multidrug resistance 2 2
TF MurR N-acetylmuramate-6-phosphate N-acetylmuramate utilization 2 2
TF NadR NAD NAD biosynthesis 3 3
TF NagC N-acetylglucosamine-6-phosphate N-acetylglucosamine utilization 5 5
TF NanR N-acetylneuraminic acid Sialic acid utilization 1 1
TF NarP Nitrate; Nitrite Nitrate and nitrite respiration 20 21
TF NhaR Potassium ion Osmotic stress response 1 2
TF NikR Nickel ion, (Ni2+) Nickel homeostasis 1 1
TF NorR Nitric oxide Nitrosative stress response 2 2
TF NrdR Deoxyribonucleotides Ribonucleotide reductases 3 7
TF NsrR Nitric oxide Nitrosative stress response 10 14
TF NtrC Phosphorylated NtrB, signal histidine kinase Nitrogen assimilation 9 18
TF PdhR Pyruvate Pyruvate metabolism 4 5
TF PhnF Phosphonate utilization 1 1
TF PurR Hypoxanthine; Guanine Purine metabolism 21 26
TF QorR Energy metabolism 2 2
TF RbsR Ribose Ribose utilization 1 1
TF RcnR Nickel ion, (Ni2+); Cobalt ion, (Co2+) Cobalt resistance; Nickel resistance 2 2
TF RutR Uracil Pyrimidine utilization 2 2
TF SdaR Glycerate Glucarate utilization; Galactarate utilization 1 1
TF SorC Sorbose Sorbose utilization 1 1
TF SoxR Paraquat Superoxide stress response 2 2
TF TreR Trehalose-6-phosphate Trehalose utilization 1 1
TF TrpR Tryptophan Tryptophan biosynthesis 4 4
TF TyrR Tyrosine; Phenylalanine Aromatic amino acid metabolism 8 14
TF UlaR Ascorbate-6-phosphate Ascorbate utilization 2 4
TF UxuR Glucuronate Glucuronate utilization 7 11
TF ZntR Zinc ion, (Zn2+) Zinc resistance 1 1
TF Zur Zinc ion, (Zn2+) Zinc homeostasis 6 7
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