Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing nanK gene

Properties
Regulog: SiaR - Pasteurellales
Regulator type: Transcription factor
Regulator family: RpiR
Regulation mode: repressor (activator)
Biological process: Sialic acid utilization
Effector: Glucosamine-6-phosphate
Phylum: Proteobacteria/gamma
Built upon 23 sites [see more]
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Actinobacillus pleuropneumoniae serovar 7 str. AP76
Position: -40
Score: 4.41535
Sequence: AATGGTGTATTTATTCATA
Locus tag: APP7_1836
Name: neuA
Funciton: Putative N-acylneuraminate cytidylyltransferase (EC 2.7.7.43)
Locus tag: APP7_1837
Name: nanE
Funciton: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Locus tag: APP7_1838
Name: nanK
Funciton: N-acetylmannosamine kinase (EC 2.7.1.60)
Locus tag: APP7_1839
Name: nanA
Funciton: N-acetylneuraminate lyase (EC 4.1.3.3)
Locus tag: APP7_1840
Name: nagB
Funciton: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
Locus tag: APP7_1841
Name: nagA
Funciton: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
neuA-nanE-nanK-nanA-nagB-nagA -40 4.4 AATGGTGTATTTATTCATA APP7_1836
Aggregatibacter aphrophilus NJ8700
Position: -156
Score: 5.29198
Sequence: AATGAAGTTTTATTTCAAA
Position: -117
Score: 4.76067
Sequence: TTTGAAATATCACTTCAAA
Locus tag: NT05HA_0545
Name: nanE
Funciton: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Locus tag: NT05HA_0546
Name: nanK
Funciton: N-acetylmannosamine kinase (EC 2.7.1.60)
Locus tag: NT05HA_0547
Name: siaR
Funciton: Sialic acid utilization regulator, RpiR family
Locus tag: NT05HA_0548
Name: nanA
Funciton: N-acetylneuraminate lyase (EC 4.1.3.3)
nanE-nanK-siaR-nanA -156 5.3 AATGAAGTTTTATTTCAAA NT05HA_0545
-117 4.8 TTTGAAATATCACTTCAAA
Haemophilus influenzae Rd KW20
Position: -163
Score: 4.76634
Sequence: TATGAAAAAACACTTCAAA
Locus tag: HI0145
Name: nanE
Funciton: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Locus tag: HI0144
Name: nanK
Funciton: N-acetylmannosamine kinase (EC 2.7.1.60)
Locus tag: HI0143
Name: siaR
Funciton: Sialic acid utilization regulator, RpiR family
Locus tag: HI0142
Name: nanA
Funciton: N-acetylneuraminate lyase (EC 4.1.3.3)
Locus tag: HI0141
Name: nagB
Funciton: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
Locus tag: HI0140
Name: nagA
Funciton: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
nanE-nanK-siaR-nanA-nagB-nagA -163 4.8 TATGAAAAAACACTTCAAA HI0145
Haemophilus parasuis SH0165
Position: -191
Score: 4.10276
Sequence: AATCGATTAAAACTCGTTT
Position: -43
Score: 4.63406
Sequence: TTTGGAGTAAATTTTCTTT
Locus tag: HAPS_1216
Name: nanE
Funciton: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Locus tag: HAPS_1215
Name: nanK
Funciton: N-acetylmannosamine kinase (EC 2.7.1.60)
nanE-nanK -191 4.1 AATCGATTAAAACTCGTTT HAPS_1216
-43 4.6 TTTGGAGTAAATTTTCTTT
Haemophilus somnus 2336
Position: -145
Score: 4.41624
Sequence: TATAGAGTTTTATTTCAGA
Position: -95
Score: 4.1005
Sequence: TCTGGAGTAAAACACCAAA
Locus tag: HSM_1111
Name: neuA
Funciton: Putative N-acylneuraminate cytidylyltransferase (EC 2.7.7.43)
Locus tag: HSM_1110
Name: nanE
Funciton: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Locus tag: HSM_1109
Name: nanK
Funciton: N-acetylmannosamine kinase (EC 2.7.1.60)
Locus tag: HSM_1108
Name: yhcH
Funciton: Uncharacterized protein yhcH
Locus tag: HSM_1107
Name: siaR
Funciton: Sialic acid utilization regulator, RpiR family
Locus tag: HSM_1106
Name: nanA
Funciton: N-acetylneuraminate lyase (EC 4.1.3.3)
neuA-nanE-nanK-yhcH-siaR-nanA -145 4.4 TATAGAGTTTTATTTCAGA HSM_1111
-95 4.1 TCTGGAGTAAAACACCAAA
Pasteurella multocida subsp. multocida str. Pm70
Position: -43
Score: 4.55186
Sequence: ATTGGAGTCAATCTTCTTT
Locus tag: PM1711
Name: nanE
Funciton: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Locus tag: PM1712
Name: nanK
Funciton: N-acetylmannosamine kinase (EC 2.7.1.60)
Locus tag: PM1713
Name: yhcH
Funciton: Uncharacterized protein yhcH
Locus tag: PM1714
Name: siaR
Funciton: Sialic acid utilization regulator, RpiR family
Locus tag: PM1715
Name: nanA
Funciton: N-acetylneuraminate lyase (EC 4.1.3.3)
nanE-nanK-yhcH-siaR-nanA -43 4.6 ATTGGAGTCAATCTTCTTT PM1711
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