Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing iscS gene

Properties
Regulog: IscR - Clostridia-3
Regulator type: Transcription factor
Regulator family: Rrf2
Regulation mode: repressor
Biological process: Iron-sulfur cluster biogenesis
Effector: Iron-sulfur cluster redox state
Phylum: Firmicutes
Built upon 9 sites [see more]
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Blautia hansenii DSM 20583
Position: -43
Score: 5.57175
Sequence: AGAAATCAGAGTAAAACAGTCGGAATTGA
Locus tag: BLAHAN_03017
Name: iscR
Funciton: Iron-sulfur cluster assembly transcription factor IscR
Locus tag: BLAHAN_03016
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7)
Locus tag: BLAHAN_03015
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU/NifU-like
Locus tag: BLAHAN_03014
Name: trmU
Funciton: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61)
iscR-iscS-iscU-trmU -43 5.6 AGAAATCAGAGTAAAACAGTCGGAATTGA BLAHAN_03017
Bryantella formatexigens DSM 14469
Position: -53
Score: 6.20065
Sequence: AGAAATCCGAGTAATTTAGTAGGATTTAA
Locus tag: BRYFOR_01246
Name: iscR
Funciton: Iron-sulfur cluster assembly transcription factor IscR
Locus tag: BRYFOR_01247
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7)
Locus tag: BRYFOR_01248
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU/NifU-like
Locus tag: BRYFOR_01249
Name: trmU
Funciton: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61)
iscR-iscS-iscU-trmU -53 6.2 AGAAATCCGAGTAATTTAGTAGGATTTAA BRYFOR_01246
Clostridium nexile DSM 1787
Position: -51
Score: 5.91229
Sequence: ATAAACCCTAGTAATTCACTAGGAATTAA
Locus tag: CLONEX_03012
Name: iscR
Funciton: Iron-sulfur cluster assembly transcription factor IscR
Locus tag: CLONEX_03011
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7)
Locus tag: CLONEX_03010
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU/NifU-like
Locus tag: CLONEX_03009
Name: trmU
Funciton: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61)
iscR-iscS-iscU-trmU -51 5.9 ATAAACCCTAGTAATTCACTAGGAATTAA CLONEX_03012
Clostridium scindens ATCC 35704
Position: 18
Score: 5.74359
Sequence: AGAAATCCTAGCAAATTGCTAGGAATTAA
Locus tag: CLOSCI_01399
Name: iscR
Funciton: Iron-sulfur cluster assembly transcription factor IscR
Locus tag: CLOSCI_01400
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7)
Locus tag: CLOSCI_01401
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU/NifU-like
Locus tag: CLOSCI_01402
Name: trmU
Funciton: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61)
iscR-iscS-iscU-trmU 18 5.7 AGAAATCCTAGCAAATTGCTAGGAATTAA CLOSCI_01399
Dorea formicigenerans ATCC 27755
Position: -37
Score: 4.69748
Sequence: TAAATCCCCAGTATTTTGCTAGGGATTGG
Locus tag: DORFOR_01426
Name: iscR
Funciton: Iron-sulfur cluster assembly transcription factor IscR
Locus tag: DORFOR_01427
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7)
Locus tag: DORFOR_01428
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU/NifU-like
Locus tag: DORFOR_01429
Name: trmU
Funciton: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61)
iscR-iscS-iscU-trmU -37 4.7 TAAATCCCCAGTATTTTGCTAGGGATTGG DORFOR_01426
Dorea longicatena DSM 13814
Position: -43
Score: 5.39194
Sequence: AAAAATCCTAGTAAAATACTGGGGATTAA
Locus tag: DORLON_02444
Name: iscR
Funciton: Iron-sulfur cluster assembly transcription factor IscR
Locus tag: DORLON_02443
Name: null
Funciton: hypothetical protein
Locus tag: DORLON_02442
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7)
Locus tag: DORLON_02441
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU/NifU-like
Locus tag: DORLON_02440
Name: trmU
Funciton: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61)
iscR-DORLON_02443-iscS-iscU-trmU -43 5.4 AAAAATCCTAGTAAAATACTGGGGATTAA DORLON_02444
Eubacterium rectale ATCC 33656
Position: -45
Score: 5.32536
Sequence: TGAATGTATAGTAAAGCAGTAGGAAATGA
Locus tag: EUBREC_0307
Name: iscR
Funciton: Iron-sulfur cluster assembly transcription factor IscR
Locus tag: EUBREC_0308
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7)
Locus tag: EUBREC_0309
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU/NifU-like
Locus tag: EUBREC_0310
Name: trmU
Funciton: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61)
iscR-iscS-iscU-trmU -45 5.3 TGAATGTATAGTAAAGCAGTAGGAAATGA EUBREC_0307
Ruminococcus gnavus ATCC 29149
Position: -60
Score: 4.49887
Sequence: GGAAATCCTAGTAAAACAATAGGGATTGG
Locus tag: RUMGNA_01751
Name: iscR
Funciton: Iron-sulfur cluster assembly transcription factor IscR
Locus tag: RUMGNA_01752
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7)
Locus tag: RUMGNA_01753
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU/NifU-like
Locus tag: RUMGNA_01754
Name: trmU
Funciton: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61)
iscR-iscS-iscU-trmU -60 4.5 GGAAATCCTAGTAAAACAATAGGGATTGG RUMGNA_01751
Ruminococcus lactaris ATCC 29176
Position: -54
Score: 4.58676
Sequence: GAAAATCCTAGTACAATACTAGGGATAAT
Locus tag: RUMLAC_01913
Name: iscR
Funciton: Iron-sulfur cluster assembly transcription factor IscR
Locus tag: RUMLAC_01914
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7)
Locus tag: RUMLAC_01915
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU/NifU-like
Locus tag: RUMLAC_01916
Name: trmU
Funciton: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61)
iscR-iscS-iscU-trmU -54 4.6 GAAAATCCTAGTACAATACTAGGGATAAT RUMLAC_01913
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