Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing hisA gene

Properties
Regulog: HisR - Thermoanaerobacterales
Regulator type: Transcription factor
Regulator family: TrpR
Regulation mode: repressor
Biological process: Histidine biosynthesis
Effector: Histidine
Phylum: Firmicutes
Built upon 8 sites [see more]
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Anaerocellum thermophilum DSM 6725
Position: -36
Score: 5.80169
Sequence: CACTTCATTATGATAAAGTA
Locus tag: Athe_1480
Name: hisZ
Funciton: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)
Locus tag: Athe_1479
Name: hisG
Funciton: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)
Locus tag: Athe_1478
Name: hisD
Funciton: Histidinol dehydrogenase (EC 1.1.1.23)
Locus tag: Athe_1477
Name: hisC
Funciton: Histidinol-phosphate aminotransferase (EC 2.6.1.9)
Locus tag: Athe_1476
Name: hisB
Funciton: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)
Locus tag: Athe_1475
Name: hisH
Funciton: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)
Locus tag: Athe_1474
Name: hisA
Funciton: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)
Locus tag: Athe_1473
Name: hisF
Funciton: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Locus tag: Athe_1472
Name: hisIE
Funciton: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
hisZ-hisG-hisD-hisC-hisB-hisH-hisA-hisF-hisIE -36 5.8 CACTTCATTATGATAAAGTA Athe_1480
Caldicellulosiruptor saccharolyticus DSM 8903
Position: -37
Score: 5.56306
Sequence: CACTTCATCATGATAAAGCA
Locus tag: Csac_2027
Name: hisZ
Funciton: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)
Locus tag: Csac_2026
Name: hisG
Funciton: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)
Locus tag: Csac_2025
Name: hisD
Funciton: Histidinol dehydrogenase (EC 1.1.1.23)
Locus tag: Csac_2024
Name: hisC
Funciton: Histidinol-phosphate aminotransferase (EC 2.6.1.9)
Locus tag: Csac_2023
Name: hisB
Funciton: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)
Locus tag: Csac_2022
Name: hisH
Funciton: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)
Locus tag: Csac_2021
Name: hisA
Funciton: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)
Locus tag: Csac_2020
Name: hisF
Funciton: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Locus tag: Csac_2019
Name: hisIE
Funciton: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
hisZ-hisG-hisD-hisC-hisB-hisH-hisA-hisF-hisIE -37 5.6 CACTTCATCATGATAAAGCA Csac_2027
Carboxydothermus hydrogenoformans Z-2901
Position: -31
Score: 5.65222
Sequence: CACTTTAACAAAATAAAGTG
Locus tag: CHY_1084
Name: hisG
Funciton: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)
Locus tag: CHY_1085
Name: hisD
Funciton: Histidinol dehydrogenase (EC 1.1.1.23)
Locus tag: CHY_1086
Name: hisC
Funciton: Histidinol-phosphate aminotransferase (EC 2.6.1.9)
Locus tag: CHY_1087
Name: hisB
Funciton: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)
Locus tag: CHY_1088
Name: hisH
Funciton: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)
Locus tag: CHY_1089
Name: hisA
Funciton: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)
Locus tag: CHY_1090
Name: hisF
Funciton: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Locus tag: CHY_1091
Name: hisIE
Funciton: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
hisG-hisD-hisC-hisB-hisH-hisA-hisF-hisIE -31 5.7 CACTTTAACAAAATAAAGTG CHY_1084
Moorella thermoacetica ATCC 39073
Position: -32
Score: 5.39704
Sequence: TACGTTAACATAGTAAAGTA
Locus tag: Moth_2037
Name: hisZ
Funciton: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)
Locus tag: Moth_2036
Name: hisG
Funciton: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)
Locus tag: Moth_2035
Name: hisD
Funciton: Histidinol dehydrogenase (EC 1.1.1.23)
Locus tag: Moth_2034
Name: hisB
Funciton: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)
Locus tag: Moth_2033
Name: hisH
Funciton: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)
Locus tag: Moth_2032
Name: hisA
Funciton: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)
Locus tag: Moth_2031
Name: hisF
Funciton: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Locus tag: Moth_2030
Name: hisIE
Funciton: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
hisZ-hisG-hisD-hisB-hisH-hisA-hisF-hisIE -32 5.4 TACGTTAACATAGTAAAGTA Moth_2037
Thermoanaerobacter ethanolicus X514
Position: -45
Score: 5.32759
Sequence: TACTTTATCACGTTACAAAG
Locus tag: Teth514_0999
Name: hisZ
Funciton: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)
Locus tag: Teth514_1000
Name: hisG
Funciton: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)
Locus tag: Teth514_1001
Name: hisD
Funciton: Histidinol dehydrogenase (EC 1.1.1.23)
Locus tag: Teth514_1002
Name: hisC
Funciton: Histidinol-phosphate aminotransferase (EC 2.6.1.9)
Locus tag: Teth514_1003
Name: hisB
Funciton: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)
Locus tag: Teth514_1004
Name: hisH
Funciton: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)
Locus tag: Teth514_1005
Name: hisA
Funciton: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)
Locus tag: Teth514_1006
Name: hisF
Funciton: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Locus tag: Teth514_1007
Name: hisIE
Funciton: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
hisZ-hisG-hisD-hisC-hisB-hisH-hisA-hisF-hisIE -45 5.3 TACTTTATCACGTTACAAAG Teth514_0999
Thermoanaerobacter italicus Ab9
Position: -45
Score: 5.32759
Sequence: TACTTTATCACGTTACAAAG
Locus tag: Thit_1821
Name: hisZ
Funciton: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)
Locus tag: Thit_1820
Name: hisG
Funciton: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)
Locus tag: Thit_1819
Name: hisD
Funciton: Histidinol dehydrogenase (EC 1.1.1.23)
Locus tag: Thit_1818
Name: hisC
Funciton: Histidinol-phosphate aminotransferase (EC 2.6.1.9)
Locus tag: Thit_1817
Name: hisB
Funciton: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)
Locus tag: Thit_1816
Name: hisH
Funciton: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)
Locus tag: Thit_1815
Name: hisA
Funciton: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)
Locus tag: Thit_1814
Name: hisF
Funciton: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Locus tag: Thit_1813
Name: hisIE
Funciton: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
hisZ-hisG-hisD-hisC-hisB-hisH-hisA-hisF-hisIE -45 5.3 TACTTTATCACGTTACAAAG Thit_1821
Thermoanaerobacter tengcongensis MB4
Position: -43
Score: 5.32759
Sequence: TACTTTATCACGTTACAAAG
Locus tag: TTE2140
Name: hisZ
Funciton: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)
Locus tag: TTE2139
Name: hisG
Funciton: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)
Locus tag: TTE2138
Name: hisD
Funciton: Histidinol dehydrogenase (EC 1.1.1.23)
Locus tag: TTE2137
Name: hisC
Funciton: Histidinol-phosphate aminotransferase (EC 2.6.1.9)
Locus tag: TTE2136
Name: hisB
Funciton: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)
Locus tag: TTE2135
Name: hisH
Funciton: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)
Locus tag: TTE2134
Name: hisA
Funciton: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)
Locus tag: TTE2133
Name: hisF
Funciton: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Locus tag: TTE2132
Name: hisIE
Funciton: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
hisZ-hisG-hisD-hisC-hisB-hisH-hisA-hisF-hisIE -43 5.3 TACTTTATCACGTTACAAAG TTE2140
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