Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing iscA gene

Properties
Regulog: IscR - Enterobacteriales
Regulator type: Transcription factor
Regulator family: Rrf2
Regulation mode: activator (repressor)
Biological process: Iron-sulfur cluster biogenesis
Effector: Iron-sulfur cluster redox state
Phylum: Proteobacteria/gamma
Built upon 45 sites [see more]
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Citrobacter koseri ATCC BAA-895
Position: -132
Score: 6.84887
Sequence: ATACCTGACTAAATTAGTCAAGTAA
Position: -107
Score: 6.02522
Sequence: ATAGTTGACTGATTTAGTCGGGAAT
Locus tag: CKO_00250
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: CKO_00251
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: CKO_00252
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: CKO_00253
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: CKO_00254
Name: hscB
Funciton: co-chaperone protein HscB
Locus tag: CKO_00255
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: CKO_00256
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: CKO_00257
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS-iscU-iscA-hscB-hscA-fdx-yfhJ -132 6.8 ATACCTGACTAAATTAGTCAAGTAA CKO_00250
-107 6 ATAGTTGACTGATTTAGTCGGGAAT
Edwardsiella tarda EIB202
Position: -114
Score: 5.72339
Sequence: ATACCTGACTAAAATAGTAGGATAA
Position: -89
Score: 6.55613
Sequence: ATAGTTGACTGAAATAGTCAGGAAT
Locus tag: ETAE_2816
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: ETAE_2815
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: ETAE_2814
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: ETAE_2813
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: ETAE_2812
Name: hscB
Funciton: co-chaperone protein HscB
Locus tag: ETAE_2811
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: ETAE_2810
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: ETAE_2809
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS-iscU-iscA-hscB-hscA-fdx-yfhJ -114 5.7 ATACCTGACTAAAATAGTAGGATAA ETAE_2816
-89 6.6 ATAGTTGACTGAAATAGTCAGGAAT
Enterobacter sp. 638
Position: -131
Score: 6.77727
Sequence: ATACCTGACTAAAACAGTCAAGTAA
Position: -106
Score: 5.92881
Sequence: ATAGTTGACCAATTTAGTCGGGAAT
Locus tag: Ent638_3028
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: Ent638_3027
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: Ent638_3026
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: Ent638_3025
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: Ent638_3024
Name: hscB
Funciton: co-chaperone protein HscB
Locus tag: Ent638_3023
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: Ent638_3022
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: Ent638_3021
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS-iscU-iscA-hscB-hscA-fdx-yfhJ -131 6.8 ATACCTGACTAAAACAGTCAAGTAA Ent638_3028
-106 5.9 ATAGTTGACCAATTTAGTCGGGAAT
Erwinia carotovora subsp. atroseptica SCRI1043
Position: -105
Score: 5.16957
Sequence: ATACTTGAGTGTTTTACTCGGTTAA
Position: -80
Score: 6.24082
Sequence: ATAGTTGACTAAAACACTCGGGAAT
Locus tag: ECA3238
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: ECA3237
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: ECA3236
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: ECA3235
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: ECA3234
Name: hscB
Funciton: co-chaperone protein HscB
Locus tag: ECA3233
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: ECA3232
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: ECA3231
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS-iscU-iscA-hscB-hscA-fdx-yfhJ -105 5.2 ATACTTGAGTGTTTTACTCGGTTAA ECA3238
-80 6.2 ATAGTTGACTAAAACACTCGGGAAT
Escherichia coli str. K-12 substr. MG1655
Position: -133
Score: 6.70926
Sequence: ATACCCGACTAAATCAGTCAAGTAA
Position: -108
Score: 5.84037
Sequence: ATAGTTGACCAATTTACTCGGGAAT
Locus tag: b2531
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: b2530
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: b2529
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: b2528
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: b2527
Name: hscB
Funciton: co-chaperone protein HscB
Locus tag: b2526
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: b2525
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: b2524
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS-iscU-iscA-hscB-hscA-fdx-yfhJ -133 6.7 ATACCCGACTAAATCAGTCAAGTAA b2531
-108 5.8 ATAGTTGACCAATTTACTCGGGAAT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Position: -127
Score: 6.77727
Sequence: ATACCTGACTAAAACAGTCAAGTAA
Position: -102
Score: 6.06229
Sequence: ATAGTTGACCAAATTACTCGGGAAT
Locus tag: KPN_02863
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: KPN_02862
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: KPN_02861
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: KPN_02860
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: KPN_02859
Name: hscB
Funciton: co-chaperone protein HscB
Locus tag: KPN_02858
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: KPN_02857
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: KPN_02856
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS-iscU-iscA-hscB-hscA-fdx-yfhJ -127 6.8 ATACCTGACTAAAACAGTCAAGTAA KPN_02863
-102 6.1 ATAGTTGACCAAATTACTCGGGAAT
Photorhabdus luminescens subsp. laumondii TTO1
Position: -90
Score: 5.41002
Sequence: ATAGTTGAGTAAATTACTAGGTTAA
Position: -65
Score: 6.62142
Sequence: ATAGTTGACTAAAATACTCAGGAAT
Locus tag: plu3284
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: plu3283
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: plu3282
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: plu3281
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: plu3280
Name: hscB
Funciton: co-chaperone protein HscB
Locus tag: plu3279
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: plu3278
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: plu3277
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS-iscU-iscA-hscB-hscA-fdx-yfhJ -90 5.4 ATAGTTGAGTAAATTACTAGGTTAA plu3284
-65 6.6 ATAGTTGACTAAAATACTCAGGAAT
Proteus mirabilis HI4320
Position: -88
Score: 6.17671
Sequence: ATACCTGACTAAAACACTCAGATAA
Position: -63
Score: 6.57706
Sequence: ATAGTTGACTAAATTACTCAGGAAT
Locus tag: PMI1861
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: PMI1860
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: PMI1859
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: PMI1858
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: PMI1857
Name: hscB
Funciton: co-chaperone protein HscB
Locus tag: PMI1856
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: PMI1855
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: PMI1854
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS-iscU-iscA-hscB-hscA-fdx-yfhJ -88 6.2 ATACCTGACTAAAACACTCAGATAA PMI1861
-63 6.6 ATAGTTGACTAAATTACTCAGGAAT
Salmonella typhimurium LT2
Position: -132
Score: 6.53852
Sequence: ATACCTGACTAATTTACTCAAGTAA
Position: -107
Score: 6.06229
Sequence: ATAGTTGACCAAATTACTCGGGAAT
Locus tag: STM2544
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: STM2543
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: STM2542
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: STM2541
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: STM2540
Name: hscB
Funciton: co-chaperone protein HscB
Locus tag: STM2539
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: STM2538
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: STM2537
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS-iscU-iscA-hscB-hscA-fdx-yfhJ -132 6.5 ATACCTGACTAATTTACTCAAGTAA STM2544
-107 6.1 ATAGTTGACCAAATTACTCGGGAAT
Serratia proteamaculans 568
Position: -94
Score: 5.44909
Sequence: ATACTTGAGTAAATTACTAGGTTAA
Position: -69
Score: 6.20142
Sequence: ATAGTTGACTGATTTACTCAGGAAT
Locus tag: Spro_3628
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: Spro_3627
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: Spro_3626
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: Spro_3625
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: Spro_3624
Name: hscB
Funciton: co-chaperone protein HscB
Locus tag: Spro_3623
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: Spro_3622
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: Spro_3621
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS-iscU-iscA-hscB-hscA-fdx-yfhJ -94 5.4 ATACTTGAGTAAATTACTAGGTTAA Spro_3628
-69 6.2 ATAGTTGACTGATTTACTCAGGAAT
Yersinia pestis KIM
Position: -29
Score: 5.25629
Sequence: ATAGTTGAGTGAATTACTAGGTTAA
Position: -4
Score: 6.57761
Sequence: ATAGTTGACTAAAACACTCAAGAAT
Locus tag: y1333
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: y1334
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: y1335
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: y1336
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: y1337
Name: null
Funciton: hypothetical
Locus tag: y1338
Name: hscB
Funciton: co-chaperone protein HscB
Locus tag: y1339
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: y1340
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: y1341
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS-iscU-iscA-y1337-hscB-hscA-fdx-yfhJ -29 5.3 ATAGTTGAGTGAATTACTAGGTTAA y1333
-4 6.6 ATAGTTGACTAAAACACTCAAGAAT
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