Orthologous regulated operons containing COG446 (HcaD) gene

Properties
Regulog:	HypR - Enterobacteriales
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:	activator (repressor)
Biological process:	Proline and 4-hydrohyproline utilization
Effector:	Proline; 4-hydroxyproline
Phylum:	Proteobacteria/gamma

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Orthologous operons
Operon	Position	Score	Sequence	Locus Tag of the First Gene
Erwinia amylovora ATCC 49946
Position: -81 Score: 3.93499 Sequence: ATCGTATACGAT Locus tag: EAM_2489 Name: COG531 (PotE) Funciton: Putative proline/hydroxyproline permease, PotE family Locus tag: EAM_2488 Name: hypD Funciton: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted Locus tag: EAM_2487 Name: hypR Funciton: Predicted regulator for proline and hydrohyproline utilization, GntR family Locus tag: EAM_2486 Name: hypE Funciton: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) Locus tag: EAM_2485 Name: hypO Funciton: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster Locus tag: EAM_2484 Name: EAM_2484 Funciton: Oxidase Locus tag: EAM_2483 Name: COG446 (HcaD) Funciton: Putative oxidoreductase in 4-hydroxyproline catabolic gene cluster Locus tag: EAM_2482 Name: hypH Funciton: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible Locus tag: EAM_2481 Name: hypS Funciton: Putative L-lactate/Malate dehydrogenase
COG531 (PotE)-hypD-hypR-hypE-hypO-EAM_2484-COG446 (HcaD)-hypH-hypS	-81	3.9	ATCGTATACGAT	EAM_2489

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --