Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing iscS2 gene

Properties
Regulog: IscR - Various betaproteobacteria
Regulator type: Transcription factor
Regulator family: Rrf2
Regulation mode: activator (repressor)
Biological process: Iron-sulfur cluster biogenesis
Effector: Iron-sulfur cluster redox state
Phylum: Proteobacteria
Built upon 27 sites [see more]
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Azoarcus sp. EbN1
Position: -91
Score: 5.56115
Sequence: GTAGTTGACCGATTTTGTCGGGTTA
Position: -63
Score: 5.84801
Sequence: ATAGTCGAGTGAAACGTTCGGGTAT
Locus tag: ebA6404
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: ebA6402
Name: iscS1
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: ebA6401
Name: iscS2
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: ebA6400
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: ebB230
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: ebA6397
Name: hscB
Funciton: Chaperone protein HscB
Locus tag: ebA6396
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: ebB229
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: ebA6395
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS1-iscS2-iscU-iscA-hscB-hscA-fdx-yfhJ -91 5.6 GTAGTTGACCGATTTTGTCGGGTTA ebA6404
-63 5.8 ATAGTCGAGTGAAACGTTCGGGTAT
Chromobacterium violaceum ATCC 12472
Position: -71
Score: 6.60071
Sequence: ATACTTGACTAATTTAGTCGGATAT
Locus tag: CV1095
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: CV1094
Name: iscS2
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: CV1093
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: CV1092
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: CV1091
Name: hscB
Funciton: Chaperone protein HscB
Locus tag: CV1090
Name: null
Funciton: hypothetical protein
Locus tag: CV1089
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: CV1088
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: CV1087
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS2-iscU-iscA-hscB-CV1090-hscA-fdx-yfhJ -71 6.6 ATACTTGACTAATTTAGTCGGATAT CV1095
Dechloromonas aromatica RCB
Position: -82
Score: 5.1747
Sequence: ATACCTGAGCAAAATAGTTGACTAA
Position: -69
Score: 6.25007
Sequence: ATAGTTGACTAATTTTCTCTGGTTT
Position: -40
Score: 5.46512
Sequence: ATAGTTGACCTTAATACTAGGTTAT
Locus tag: Daro_1948
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: Daro_1949
Name: iscS1
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: Daro_1950
Name: iscS2
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: Daro_1951
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: Daro_1952
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: Daro_1953
Name: hscB
Funciton: Chaperone protein HscB
Locus tag: Daro_1954
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: Daro_1955
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: Daro_1956
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS1-iscS2-iscU-iscA-hscB-hscA-fdx-yfhJ -82 5.2 ATACCTGAGCAAAATAGTTGACTAA Daro_1948
-69 6.3 ATAGTTGACTAATTTTCTCTGGTTT
-40 5.5 ATAGTTGACCTTAATACTAGGTTAT
Laribacter hongkongensis HLHK9
Position: -63
Score: 6.39685
Sequence: ATGGTTGACTAAATTAGTCGGGTTT
Locus tag: LHK_02866
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: LHK_02865
Name: iscS2
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: LHK_02864
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: LHK_02863
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: LHK_02862
Name: hscB
Funciton: Chaperone protein HscB
Locus tag: LHK_02861
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: LHK_02860
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: LHK_02859
Name: null
Funciton: YbaK/prolyl-tRNA synthetase associated region
Locus tag: LHK_02858
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS2-iscU-iscA-hscB-hscA-fdx-LHK_02859-yfhJ -63 6.4 ATGGTTGACTAAATTAGTCGGGTTT LHK_02866
Methylobacillus flagellatus KT
Position: -111
Score: 6.32029
Sequence: ATAGTTGACTAAAGTATTCAGGTAT
Locus tag: Mfla_0810
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: Mfla_0809
Name: iscS1
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: Mfla_0808
Name: iscS2
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: Mfla_0807
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: Mfla_0806
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: Mfla_0805
Name: hscB
Funciton: Chaperone protein HscB
Locus tag: Mfla_0804
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: Mfla_0803
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
iscR-iscS1-iscS2-iscU-iscA-hscB-hscA-fdx -111 6.3 ATAGTTGACTAAAGTATTCAGGTAT Mfla_0810
Methylophilales bacterium HTCC2181
Position: -58
Score: 5.64876
Sequence: ATACTTGATAGTTTTAGTCAAGTAT
Locus tag: MB2181_02930
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: MB2181_02925
Name: iscS1
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: MB2181_02920
Name: iscS2
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: MB2181_02915
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: MB2181_02910
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: MB2181_02905
Name: hscB
Funciton: Chaperone protein HscB
Locus tag: MB2181_02900
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: MB2181_02895
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
iscR-iscS1-iscS2-iscU-iscA-hscB-hscA-fdx -58 5.6 ATACTTGATAGTTTTAGTCAAGTAT MB2181_02930
Methylotenera mobilis JLW8
Position: -70
Score: 6.33884
Sequence: ATAGTTGACTAAAATTGTAAGGAAT
Locus tag: Mmol_1671
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: Mmol_1672
Name: iscS1
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: Mmol_1673
Name: iscS2
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
iscR-iscS1-iscS2 -70 6.3 ATAGTTGACTAAAATTGTAAGGAAT Mmol_1671
Neisseria meningitidis MC58
Position: -74
Score: 6.26978
Sequence: ATACTTGACTGAAACACTCAGATAT
Locus tag: NMB1378
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: NMB1379
Name: iscS2
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
iscR-iscS2 -74 6.3 ATACTTGACTGAAACACTCAGATAT NMB1378
Thauera sp. MZ1T
Position: -103
Score: 5.12715
Sequence: TTAGTTGACCGTTTTTGTCGGGATC
Position: -75
Score: 5.58039
Sequence: ATACTCGACAAAAATGATGGGATAT
Locus tag: Tmz1t_2207
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: Tmz1t_2206
Name: iscS1
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: Tmz1t_2205
Name: iscS2
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: Tmz1t_2204
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: Tmz1t_2203
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: Tmz1t_2202
Name: hscB
Funciton: Chaperone protein HscB
Locus tag: Tmz1t_2201
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: Tmz1t_2200
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: Tmz1t_2199
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS1-iscS2-iscU-iscA-hscB-hscA-fdx-yfhJ -103 5.1 TTAGTTGACCGTTTTTGTCGGGATC Tmz1t_2207
-75 5.6 ATACTCGACAAAAATGATGGGATAT
Thiobacillus denitrificans
Position: -88
Score: 6.17141
Sequence: ATAGTTGACTAAATTGCTAAGGTAA
Position: -60
Score: 6.48102
Sequence: ATAGTTGACTGAAATGCTCGGGAAT
Locus tag: Tbd_1163
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR
Locus tag: Tbd_1164
Name: iscS2
Funciton: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
Locus tag: Tbd_1165
Name: iscU
Funciton: Iron-sulfur cluster assembly scaffold protein IscU
Locus tag: Tbd_1166
Name: iscA
Funciton: Iron binding protein IscA for iron-sulfur cluster assembly
Locus tag: Tbd_1167
Name: hscB
Funciton: Chaperone protein HscB
Locus tag: Tbd_1168
Name: hscA
Funciton: Chaperone protein HscA
Locus tag: Tbd_1169
Name: fdx
Funciton: ferredoxin, 2Fe-2S type, ISC system
Locus tag: Tbd_1170
Name: yfhJ
Funciton: putative Fe-S cluster assembly protein
iscR-iscS2-iscU-iscA-hscB-hscA-fdx-yfhJ -88 6.2 ATAGTTGACTAAATTGCTAAGGTAA Tbd_1163
-60 6.5 ATAGTTGACTGAAATGCTCGGGAAT
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