Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of PurR in Geobacillus kaustophilus HTA426

Properties
Regulator type: Transcription factor
TF locus tag: GK0040
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Bacillales
Statistics of regulated genes:
- Genes 23
- Operons 8
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 102 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -39
Score: 8.4
Sequence: TATATCGAACATTT-(17)-GAAAGTTCGTGTTT
Locus tag: GK1569
Name: null
Funciton: Uncharacterized FAD-dependent dehydrogenase
GK1569
Uncharacterized FAD-dependent dehydrogenase
Position: -120
Score: 8.7
Sequence: AAATCCGAATGATT-(17)-TTTCATTCATTTTT
Locus tag: GK3369
Name: glyA
Funciton: Serine hydroxymethyltransferase (EC 2.1.2.1)
GK3369
glyA
Serine hydroxymethyltransferase (EC 2.1.2.1)
Position: -57
Score: 9
Sequence: AAACACGTACATTT-(17)-TAATATTCGGTTTC
Locus tag: GK0040
Name: purR
Funciton: Transcriptional repressor of the purine biosinthesis, PurR family
Locus tag: GK0041
Name: yabJ
Funciton: Translation initiation inhibitor, yjgF family
GK0040
purR
Transcriptional repressor of the purine biosinthesis, PurR family
GK0041
yabJ
Translation initiation inhibitor, yjgF family
Position: -302
Score: 9.6
Sequence: AAACACGAACATTT-(16)-AAATGTTCGATTTT
Locus tag: GK0257
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: GK0258
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
Locus tag: GK0259
Name: purB
Funciton: Adenylosuccinate lyase (EC 4.3.2.2)
Locus tag: GK0260
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: GK0261
Name: purS
Funciton: Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
Locus tag: GK0262
Name: purQ
Funciton: Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: GK0263
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
Locus tag: GK0264
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: GK0265
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: GK0266
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
Locus tag: GK0267
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Locus tag: GK0268
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
GK0257
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
GK0258
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
GK0259
purB
Adenylosuccinate lyase (EC 4.3.2.2)
GK0260
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
GK0261
purS
Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
GK0262
purQ
Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
GK0263
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
GK0264
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
GK0265
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
GK0266
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
GK0267
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
GK0268
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Position: -113
Score: 9.4
Sequence: ATAAACGAATAAAA-(17)-TAATGTTCGTGTTT
Locus tag: GK3475
Name: purA
Funciton: Adenylosuccinate synthetase (EC 6.3.4.4)
GK3475
purA
Adenylosuccinate synthetase (EC 6.3.4.4)
Position: -63
Score: 8.4
Sequence: TTTTCCGAAAAATA-(17)-GAATGTTCGTTTTT
Locus tag: GK2397
Name: nusB
Funciton: Transcription termination factor
Locus tag: GK2396
Name: folD
Funciton: Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
GK2397
nusB
Transcription termination factor
GK2396
folD
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
Position: -292
Score: 9.6
Sequence: AAAAACGAACAAAA-(17)-AAATGTTCGTCTTT
Locus tag: GK0255
Name: pbuG
Funciton: Hypoxanthine/guanine permease PbuG
GK0255
pbuG
Hypoxanthine/guanine permease PbuG
Position: -436
Score: 8
Sequence: AAACAAGAACATTA-(17)-GAAAGTTCGATTAT
Locus tag: GK2425
Name: null
Funciton: Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10)
Locus tag: GK2424
Name: gcvPA
Funciton: Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein) (EC 1.4.4.2)
Locus tag: GK2423
Name: gcvPB
Funciton: Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein) (EC 1.4.4.2)
GK2425
Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10)
GK2424
gcvPA
Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein) (EC 1.4.4.2)
GK2423
gcvPB
Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein) (EC 1.4.4.2)
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