Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of PurR in Bacillus subtilis subsp. subtilis str. 168

Properties
Regulator type: Transcription factor
TF locus tag: BSU00470
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Bacillales
Statistics of regulated genes:
- Genes 24
- Operons 10
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 102 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -279
Score: 8.6
Sequence: AAATACGAATGATA-(16)-TAAAGTTCGGGAAT
Locus tag: BSU22070
Name: xpt
Funciton: Xanthine phosphoribosyltransferase (EC 2.4.2.22)
Locus tag: BSU22060
Name: pbuX
Funciton: Xanthine permease
xpt
Xanthine phosphoribosyltransferase (EC 2.4.2.22)
pbuX
Xanthine permease

Position: -320
Score: 8.9
Sequence: TATTACGAACAAAA-(16)-TATTGTTCGCTTTT
Locus tag: BSU06370
Name: pbuG
Funciton: Hypoxanthine/guanine permease PbuG
pbuG
Hypoxanthine/guanine permease PbuG

Position: -149
Score: 9
Sequence: AAATCCGAATAATC-(16)-AAATATTCGGTAAT
Locus tag: BSU24320
Name: nusB
Funciton: Transcription termination factor
Locus tag: BSU24310
Name: folD
Funciton: Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
nusB
Transcription termination factor
folD
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)

Position: -57
Score: 9.2
Sequence: AAATCCGTATGTTA-(16)-AAATATTCGGATTT
Locus tag: BSU00470
Name: purR
Funciton: Transcriptional repressor of the purine biosinthesis, PurR family
Locus tag: BSU00480
Name: yabJ
Funciton: Translation initiation inhibitor, yjgF family
purR
Transcriptional repressor of the purine biosinthesis, PurR family
yabJ
Translation initiation inhibitor, yjgF family

Position: -128
Score: 8.2
Sequence: GGAAGCGAACGAAT-(17)-TAATGTTCGGATTT
Locus tag: BSU40420
Name: purA
Funciton: Adenylosuccinate synthetase (EC 6.3.4.4)
purA
Adenylosuccinate synthetase (EC 6.3.4.4)

Position: -57
Score: 9.2
Sequence: TAAGGCGAACATTT-(16)-AAATATTCGTTTTT
Locus tag: BSU32130
Name: guaC
Funciton: GMP reductase (EC 1.7.1.7)
guaC
GMP reductase (EC 1.7.1.7)

Position: -159
Score: 9.2
Sequence: AATTCCGAACTTTA-(17)-TAATATTCGTTTTT
Locus tag: BSU36900
Name: glyA
Funciton: Serine hydroxymethyltransferase (EC 2.1.2.1)
glyA
Serine hydroxymethyltransferase (EC 2.1.2.1)

Position: -55
Score: 9.2
Sequence: TAAAACGAATAATA-(17)-AAACGTTCGTAATT
Locus tag: BSU29990
Name: pbuO
Funciton: Xanthine/uracil/thiamine/ascorbate permease family protein
pbuO
Xanthine/uracil/thiamine/ascorbate permease family protein

Position: -323
Score: 9
Sequence: AAACACGAACATTA-(16)-TATCGTTCGATAAT
Locus tag: BSU06420
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: BSU06430
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
Locus tag: BSU06440
Name: purB
Funciton: Adenylosuccinate lyase (EC 4.3.2.2)
Locus tag: BSU06450
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: BSU06460
Name: purS
Funciton: Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
Locus tag: BSU06470
Name: purQ
Funciton: Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: BSU06480
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
Locus tag: BSU06490
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: BSU06500
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
Locus tag: BSU06510
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
Locus tag: BSU06520
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Locus tag: BSU06530
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purB
Adenylosuccinate lyase (EC 4.3.2.2)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purS
Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
purQ
Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)

Position: -206
Score: 8.6
Sequence: AAACACGAACTTTG-(17)-TTTTATTCGTTTAT
Position: -103
Score: 6.7
Sequence: AAATCAGAAAATTT-(17)-TAAAATAGGGTTTA
Locus tag: BSU12860
Name: steT
Funciton: Serine/threonine exchanger SteT
steT
Serine/threonine exchanger SteT
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