Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of PurR in Bacillus clausii KSM-K16

Properties
Regulator type: Transcription factor
TF locus tag: ABC0075
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Bacillales
Statistics of regulated genes:
- Genes 26
- Operons 9
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 102 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -59
Score: 8.5
Sequence: AAATACGGATGAAA-(16)-AAATATTCGGTTAT
Locus tag: ABC0075
Name: purR
Funciton: Transcriptional repressor of the purine biosinthesis, PurR family
Locus tag: ABC0076
Name: yabJ
Funciton: Translation initiation inhibitor, yjgF family
purR
Transcriptional repressor of the purine biosinthesis, PurR family
yabJ
Translation initiation inhibitor, yjgF family

Position: -470
Score: 6.8
Sequence: AATGCCGAAAACAA-(16)-TTTGGTTCGTTGTT
Position: -305
Score: 9
Sequence: AAAAACGAACAATG-(16)-AAATGTTCGACTAT
Locus tag: ABC1024
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: ABC1025
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
Locus tag: ABC1026
Name: purB
Funciton: Adenylosuccinate lyase (EC 4.3.2.2)
Locus tag: ABC1027
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: ABC1028
Name: purS
Funciton: Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
Locus tag: ABC1029
Name: purQ
Funciton: Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: ABC1030
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
Locus tag: ABC1031
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: ABC1032
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: ABC1033
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
Locus tag: ABC1034
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Locus tag: ABC1035
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purB
Adenylosuccinate lyase (EC 4.3.2.2)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purS
Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
purQ
Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)

Position: -65
Score: 7.2
Sequence: AAAGCCGAAAGATC-(16)-GGTCTTTCGGCTTT
Locus tag: ABC1443
Name: xpt
Funciton: Xanthine phosphoribosyltransferase (EC 2.4.2.22)
Locus tag: ABC1444
Name: null
Funciton: Xanthine permease
xpt
Xanthine phosphoribosyltransferase (EC 2.4.2.22)
Xanthine permease

Position: -73
Score: 7
Sequence: GATCATGTATATTA-(17)-TTTTGTTCTTTTAT
Position: -55
Score: 8.2
Sequence: ATGGGCGAATGATT-(17)-TAACATTCGTTTTT
Locus tag: ABC3216
Name: guaC
Funciton: GMP reductase (EC 1.7.1.7)
guaC
GMP reductase (EC 1.7.1.7)

Position: -125
Score: 6.4
Sequence: GAAACTGAATAAAA-(16)-TATCTTCCGGAAAA
Locus tag: ABC3863
Name: glyA
Funciton: Serine hydroxymethyltransferase (EC 2.1.2.1)
glyA
Serine hydroxymethyltransferase (EC 2.1.2.1)

Position: -258
Score: 8.7
Sequence: GAAGACGAATAATG-(16)-CATTGTTCGTTTTT
Locus tag: ABC0959
Name: pbuG
Funciton: Hypoxanthine/guanine permease PbuG
pbuG
Hypoxanthine/guanine permease PbuG

Position: -111
Score: 8.1
Sequence: TTATACGAATGTTG-(16)-AAATGTTCGTGTCT
Locus tag: ABC4100
Name: purA
Funciton: Adenylosuccinate synthetase (EC 6.3.4.4)
purA
Adenylosuccinate synthetase (EC 6.3.4.4)

Position: -480
Score: 6.8
Sequence: AGAACCGAACATTC-(16)-TAATGTTAATATCC
Locus tag: ABC2495
Name: gcvT
Funciton: Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10)
Locus tag: ABC2494
Name: gcvPA
Funciton: Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein) (EC 1.4.4.2)
Locus tag: ABC2493
Name: gcvPB
Funciton: Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein) (EC 1.4.4.2)
gcvT
Aminomethyltransferase (glycine cleavage system T protein) (EC 2.1.2.10)
gcvPA
Glycine dehydrogenase [decarboxylating] (glycine cleavage system P1 protein) (EC 1.4.4.2)
gcvPB
Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein) (EC 1.4.4.2)

Position: -109
Score: 7.6
Sequence: AAATCCGAACATTA-(16)-GAATGTAAAGAATT
Locus tag: ABC2870
Name: null
Funciton: N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)
Locus tag: ABC2869
Name: null
Funciton: Membrane protein
Locus tag: ABC2868
Name: null
Funciton: Hypothetical protein
N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)
Membrane protein
Hypothetical protein
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