Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulog MepR - Staphylococcaceae

Properties
Regulator type: Transcription factor
Regulator family: MarR
Regulation mode: repressor
Biological process: Multidrug resistance
Effector: Bis-indoles; Distamycin
Phylum: Firmicutes
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 12 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Staphylococcus aureus subsp. aureus N315 2 2
Staphylococcus capitis SK14
Staphylococcus epidermidis ATCC 12228
Staphylococcus carnosus subsp. carnosus TM300 2 2
Staphylococcus haemolyticus JCSC1435 3 2
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 2 2
Macrococcus caseolyticus JCSC5402
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
mepR
*
Staphylococcus aureus subsp. aureus N315

Site:
position = -34
score = 6.20324
sequence = TAGTTAGACATCTAACGA

Gene: SA0322: multidrug binding repressor, MarR family
 
Staphylococcus capitis SK14
 
Staphylococcus epidermidis ATCC 12228
*
Staphylococcus carnosus subsp. carnosus TM300

Site:
position = -34
score = 6.00734
sequence = TAGTTAGACTTCTAACGA

Gene: Sca_2432: multidrug binding repressor, MarR family
*
Staphylococcus haemolyticus JCSC1435

Site:
position = -32
score = 6.02966
sequence = TCGTTAGACATCTAACGA

Gene: SH0675: multidrug binding repressor, MarR family
*
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305

Site:
position = -32
score = 6.25564
sequence = TCGTTAGATATCTAATTA

Gene: SSP2141: multidrug binding repressor, MarR family
 
Macrococcus caseolyticus JCSC5402
multidrug binding repressor, MarR family
 
CRON 2.
mepA
*
Staphylococcus aureus subsp. aureus N315

Site:
position = -59
score = 6.04792
sequence = TAGTTAGATATCTAATTG

Site:
position = -44
score = 5.1297
sequence = TTGTTAGTAAGCTAATTA

Gene: SA0323: Na+-driven multidrug efflux pump, MATE family
 
Staphylococcus capitis SK14
 
Staphylococcus epidermidis ATCC 12228
*
Staphylococcus carnosus subsp. carnosus TM300

Site:
position = -63
score = 5.5635
sequence = TAGTTAGAACTTTAACTA

Site:
position = -48
score = 5.38158
sequence = CTATTAGAACTCTAACTA

Gene: Sca_2433: Na+-driven multidrug efflux pump, MATE family
*2
Staphylococcus haemolyticus JCSC1435

Gene: SH0677: Na+-driven multidrug efflux pump, MATE family

Site:
position = -49
score = 6.42922
sequence = TAGTTAGATATCTAATTA

Site:
position = -34
score = 5.45638
sequence = TTATTAGACATCTAACAT

Gene: SH0676: Na+-driven multidrug efflux pump, MATE family
*
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305

Site:
position = -51
score = 6.42922
sequence = TAGTTAGATATCTAATTA

Site:
position = -36
score = 5.22437
sequence = TTATTAGGTGTCTAAATA

Gene: SSP2140: Na+-driven multidrug efflux pump, MATE family
 
Macrococcus caseolyticus JCSC5402
Na+-driven multidrug efflux pump, MATE family
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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